Manikkam Suthanthiran

Affiliations

Division of Nephrology and Hypertension, Department of Medicine, Weill Cornell Medical College, New York, New York, USA.
Department of Transplantation Medicine, NewYork-Presbyterian/Weill Cornell Medical Center, New York, New York, USA.

Publications (37)

Urinary cell transcriptomics and acute rejection in human kidney allografts.

JCI insight

Avec: Akanksha Verma , Thangamani Muthukumar , Hua Yang , Michelle Lubetzky , Michael F Cassidy , John R Lee , Darshana M Dadhania , Catherine Snopkowski , Divya Shankaranarayanan , Steven P Salvatore , Vijay K Sharma , Jenny Z Xiang , Iwijn De Vlaminck , Surya V Seshan , Franco B Mueller , Karsten Suhre , Olivier Elemento , Manikkam Suthanthiran

Butyrate-producing gut bacteria and viral infections in kidney transplant recipients: A pilot study.

Transplant infectious disease : an official journal of the Transplantation Society

Avec: John R Lee , Jennifer Huang , Matthew Magruder , Lisa T Zhang , Catherine Gong , Adam N Sholi , Shady Albakry , Emmanuel Edusei , Thangamani Muthukumar , Michelle Lubetzky , Darshana M Dadhania , Ying Taur , Eric G Pamer , Manikkam Suthanthiran

Measurement Biases Distort Cell-Free DNA Fragmentation Profiles and Define the Sensitivity of Metagenomic Cell-Free DNA Sequencing Assays.

Clinical chemistry

Avec: Adrienne Chang , Omary Mzava , Joan S Lenz , Alexandre P Cheng , Philip Burnham , S Timothy Motley , Crissa Bennett , John T Connelly , Darshana M Dadhania , Manikkam Suthanthiran , John R Lee , Amy Steadman , Iwijn De Vlaminck

Validation of a noninvasive prognostic signature for allograft failure following BK virus associated nephropathy.

Clinical transplantation

Avec: Essa Abuhelaiqa , Catherine Snopkowski , Carol Li , Steve Salvatore , John R Lee , Thangamani Muthukumar , Jun B Lee , Choli Hartono , Ruchuang Ding , Surya V Seshan , Manikkam Suthanthiran , Darshana M Dadhania

Blockade of store-operated calcium entry by BTP2 preserves anti-inflammatory gene expression in human peripheral blood mononuclear cells.

Human immunology

Avec: Divya Shankaranarayanan , Madhav Mantri , Mila Lagman , Carol Li , Vijay K Sharma , Thangamani Muthukumar , Jenny Z Xiang , Iwijn De Vlaminck , Khaled Machaca , Manikkam Suthanthiran

MicroRNAs and Transplantation.

Clinics in laboratory medicine

Avec: Zahraa Khan , Manikkam Suthanthiran , Thangamani Muthukumar

Gut microbiota dysbiosis and diarrhea in kidney transplant recipients.

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons

Avec: John Richard Lee , Matthew Magruder , Lisa Zhang , Lars F Westblade , Michael J Satlin , Amy Robertson , Emmanuel Edusei , Carl Crawford , Lilan Ling , Ying Taur , Jonas Schluter , Michelle Lubetzky , Darshana Dadhania , Eric Pamer , Manikkam Suthanthiran

Kidney allograft recipients, immunosuppression, and coronavirus disease-2019: a report of consecutive cases from a New York City transplant center.

Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association

Avec: Michelle Lubetzky , Meredith J Aull , Rebecca Craig-Schapiro , John R Lee , Jehona Marku-Podvorica , Thalia Salinas , Laura Gingras , Jun B Lee , Samuel Sultan , Rosy Priya Kodiyanplakkal , Choli Hartono , Stuart Saal , Thangamani Muthukumar , Sandip Kapur , Manikkam Suthanthiran , Darshana M Dadhania

Selective modulation of gene expression in activated normal human peripheral blood mononuclear cells by store-operated calcium entry blocker BTP2.

Research square

Avec: Divya Shankaranarayanan , Madhav Mantri , Mila Lagman , Carol Li , Vijay K Sharma , Thangamani Muthukumar , Jenny Z Xiang , Iwijn De Vlaminck , Khaled Machaca , Manikkam Suthanthiran

Evaluation of Immunocompetence and Biomarkers of Tolerance in Chimeric and Immunosuppression-free Kidney Allograft Recipients.

Transplantation

Avec: Joseph R Leventhal , John Galvin , Michael G Ison , Chris Yuhsuen Feng , Ruchuang Ding , John R Lee , Carol Li , James M Mathew , Lorenzo Gallon , Meg Gibson , Dianne Belshe , David J Tollerud , Eric Gornstein , Manikkam Suthanthiran , Suzanne T Ildstad

Separating the signal from the noise in metagenomic cell-free DNA sequencing.

Microbiome

Avec: Philip Burnham , Nardhy Gomez-Lopez , Michael Heyang , Alexandre Pellan Cheng , Joan Sesing Lenz , Darshana M Dadhania , John Richard Lee , Manikkam Suthanthiran , Roberto Romero , Iwijn De Vlaminck

A cell-free DNA metagenomic sequencing assay that integrates the host injury response to infection.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Alexandre Pellan Cheng , Philip Burnham , John Richard Lee , Matthew Pellan Cheng , Manikkam Suthanthiran , Darshana Dadhania , Iwijn De Vlaminck

Serum MicroRNA Transcriptomics and Acute Rejection or Recurrent Hepatitis C Virus in Human Liver Allograft Recipients: A Pilot Study.

Transplantation

Avec: Thangamani Muthukumar , Kemal M Akat , Hua Yang , Joseph E Schwartz , Carol Li , Heejung Bang , Iddo Z Ben-Dov , John R Lee , David Ikle , Anthony J Demetris , Thomas Tuschl , Manikkam Suthanthiran

T-Cell-Positive, B-Cell-Negative Flow Cytometry Crossmatch: Frequency, HLA Locus Specificity, and Mechanisms Among 3073 Clinical Flow Cytometry Crossmatch Tests.

Experimental and clinical transplantation : official journal of the Middle East Society for Organ Transplantation

Avec: Prabhakar Putheti , Vijay K Sharma , Rex Friedlander , Arvind Menon , Darshana Dadhania , Thangamani Muthukumar , Manikkam Suthanthiran

Development of a Bak gene based standard curve for absolute quantification of BK virus in real time quantitative PCR assay and noninvasive diagnosis of BK virus nephropathy in kidney allograft recipients.

Journal of immunological methods

Avec: Carol Li , Clayton Hughes , Ruchuang Ding , Catherine Snopkowski , Thalia Salinas , Joseph Schwartz , Darshana Dadhania , Manikkam Suthanthiran

Urinary cell mRNA profiling of kidney allograft recipients: Development of a portable protocol for noninvasive diagnosis of T cell mediated rejection and BK virus nephropathy.

Journal of immunological methods

Avec: Thalia Salinas , Carol Li , Catherine Snopkowski , Gabriel Stryjniak , Divya Shankaranarayanan , Shady Albakry , Ruchuang Ding , Vijay K Sharma , Steven P Salvatore , Surya V Seshan , Darshana M Dadhania , Thangamani Muthukumar , Manikkam Suthanthiran

Transcriptomic signatures of chronic active antibody-mediated rejection deciphered by RNA sequencing of human kidney allografts.

Kidney international

Avec: Yajas Shah , Hua Yang , Franco B Mueller , Carol Li , Shab E Gul Rahim , Elly Varma , Thalia Salinas , Darshana M Dadhania , Steven Salvatore , Surya V Seshan , Vijay K Sharma , Olivier Elemento , Manikkam Suthanthiran , Thangamani Muthukumar

A quantitative comparison of urine centrifugation and filtration for the isolation and analysis of urinary nucleic acid biomarkers.

Scientific reports

Avec: Liz-Audrey Kounatse Djomnang , Carol Li , Omary Mzava , Alexandre Pellan Cheng , Adrienne Chang , Joan Sesing Lenz , Manikkam Suthanthiran , John R Lee , Darshana M Dadhania , Iwijn De Vlaminck

Urinary Cell mRNA Profiles Predictive of Human Kidney Allograft Status.

Clinical journal of the American Society of Nephrology : CJASN

Avec: Michelle L Lubetzky , Thalia Salinas , Joseph E Schwartz , Manikkam Suthanthiran

FOXP3 mRNA Profile Prognostic of Acute T Cell-mediated Rejection and Human Kidney Allograft Survival.

Transplantation

Avec: Danny Luan , Darshana M Dadhania , Ruchuang Ding , Thangamani Muthukumar , Michelle Lubetzky , John R Lee , Vijay K Sharma , Phyllis August , Franco B Mueller , Joseph E Schwartz , Manikkam Suthanthiran

Gastrointestinal pathogen colonization and the microbiome in asymptomatic kidney transplant recipients.

Transplant infectious disease : an official journal of the Transplantation Society

Avec: Lars F Westblade , Michael J Satlin , Shady Albakry , Brittany Botticelli , Amy Robertson , Tricia Alston , Matthew Magruder , Lisa T Zhang , Emmanuel Edusei , Kevin Chan , Michelle Lubetzky , Darshana M Dadhania , Eric G Pamer , Manikkam Suthanthiran , John R Lee

Kidney Allograft Function Is a Confounder of Urine Metabolite Profiles in Kidney Allograft Recipients.

Metabolites

Avec: Karsten Suhre , Darshana M Dadhania , John Richard Lee , Thangamani Muthukumar , Qiuying Chen , Steven S Gross , Manikkam Suthanthiran

Detection of infiltrating fibroblasts by single-cell transcriptomics in human kidney allografts.

PloS one

Avec: Hemant Suryawanshi , Hua Yang , Michelle Lubetzky , Pavel Morozov , Mila Lagman , Gaurav Thareja , Alicia Alonso , Carol Li , Catherine Snopkowski , Aziz Belkadi , Franco B Mueller , John R Lee , Darshana M Dadhania , Steven P Salvatore , Surya V Seshan , Vijay K Sharma , Karsten Suhre , Manikkam Suthanthiran , Thomas Tuschl , Thangamani Muthukumar

Design and Methods of the Validating Injury to the Renal Transplant Using Urinary Signatures (VIRTUUS) Study in Children.

Transplantation direct

Avec: Juhi Kumar , Kévin Contrepois , Michael Snyder , Paul C Grimm , Asha Moudgil , Jodi M Smith , Amy E Bobrowski , Priya S Verghese , David Hooper , Elizabeth Ingulli , Rachel Lestz , Patricia Weng , Janaiya L Reason , Tom D Blydt-Hansen , Manikkam Suthanthiran , Brendan Keating , Sandra Amaral

A universal urinary cell gene signature of acute rejection in kidney allografts.

Journal of immunological methods

Avec: Thalia Salinas , Carol Li , Catherine Snopkowski , Vijay K Sharma , Darshana M Dadhania , Karsten Suhre , Thangamani Muthukumar , Manikkam Suthanthiran

Chronic reduction of store operated Ca

The Journal of physiology

Avec: Fang Yu , Raphael Courjaret , Asha Elmi , Ethel Alcantara Adap , Nelson N Orie , Fawzi Zghyer , Satanay Hubrack , Sajad Hayat , Nidal Asaad , Stefan Worgall , Manikkam Suthanthiran , Vidya Mohamed Ali , Khaled Machaca

Urine as liquid gold: the transcriptional landscape of acute rejection defined by urinary cell mRNA profiling of kidney allograft recipients.

Current opinion in organ transplantation

Avec: Manikkam Suthanthiran

Antibiotic subclasses differentially perturb the gut microbiota in kidney transplant recipients.

Frontiers in transplantation

Avec: Hanbo Dong , Runzhe Li , Ni Zhao , Darshana M Dadhania , Manikkam Suthanthiran , John R Lee , Wodan Ling

Urinary Cell Transcriptome Profiling and Identification of ITM2A, SLAMF6, and IKZF3 as Biomarkers of Acute Rejection in Human Kidney Allografts.

Transplantation direct

Avec: Bryan J Dooley , Akanksha Verma , Ruchuang Ding , Hua Yang , Thangamani Muthukumar , Michele Lubetzky , Divya Shankaranarayanan , Olivier Elemento , Manikkam Suthanthiran

Landscape of innate immune system transcriptome and acute T cell-mediated rejection of human kidney allografts.

JCI insight

Avec: Franco B Mueller , Hua Yang , Michelle Lubetzky , Akanksha Verma , John R Lee , Darshana M Dadhania , Jenny Z Xiang , Steven P Salvatore , Surya V Seshan , Vijay K Sharma , Olivier Elemento , Manikkam Suthanthiran , Thangamani Muthukumar

Gut uropathogen abundance is a risk factor for development of bacteriuria and urinary tract infection.

Nature communications

Avec: Matthew Magruder , Adam N Sholi , Catherine Gong , Lisa Zhang , Emmanuel Edusei , Jennifer Huang , Shady Albakry , Michael J Satlin , Lars F Westblade , Carl Crawford , Darshana M Dadhania , Michelle Lubetzky , Ying Taur , Eric Littman , Lilan Ling , Philip Burnham , Iwijn De Vlaminck , Eric Pamer , Manikkam Suthanthiran , John Richard Lee

A metagenomic DNA sequencing assay that is robust against environmental DNA contamination.

bioRxiv : the preprint server for biology

Avec: Omary Mzava , Alexandre Pellan Cheng , Adrienne Chang , Sami Smalling , Liz-Audrey Djomnang Kounatse , Joan Lenz , Randy Longman , Amy Steadman , Mirella Salvatore , Manikkam Suthanthiran , John R Lee , Christopher E Mason , Darshana Dadhania , Iwijn De Vlaminck

Deep sequencing of DNA from urine of kidney allograft recipients to estimate donor/recipient-specific DNA fractions.

PloS one

Avec: Aziz Belkadi , Gaurav Thareja , Darshana Dadhania , John R Lee , Thangamani Muthukumar , Catherine Snopkowski , Carol Li , Anna Halama , Sara Abdelkader , Silvana Abdulla , Yasmin Mahmoud , Joel Malek , Manikkam Suthanthiran , Karsten Suhre

Urinary cell mRNA profiling of kidney allograft recipients: A systematic investigation of a filtration based protocol for the simplification of urine processing.

Journal of immunological methods

Avec: Catherine Snopkowski , Thalia Salinas , Carol Li , Gabriel Stryjniak , Ruchuang Ding , Vijay Sharma , Manikkam Suthanthiran

Urinary Cell Gene Signature of Acute Rejection in Kidney Allografts.

medRxiv : the preprint server for health sciences

Avec: Thalia Salinas , Carol Li , Catherine Snopkowski , Vijay K Sharma , Darshana M Dadhania , Karsten Suhre , Thangamani Muthukumar , Manikkam Suthanthiran

A metagenomic DNA sequencing assay that is robust against environmental DNA contamination.

Nature communications

Avec: Omary Mzava , Alexandre Pellan Cheng , Adrienne Chang , Sami Smalling , Liz-Audrey Kounatse Djomnang , Joan Sesing Lenz , Randy Longman , Amy Steadman , Luis G Gómez-Escobar , Edward J Schenck , Mirella Salvatore , Michael J Satlin , Manikkam Suthanthiran , John R Lee , Christopher E Mason , Darshana Dadhania , Iwijn De Vlaminck

RNA-sequencing of Human Kidney Allografts and Delineation of T-Cell Genes, Gene Sets, and Pathways Associated With Acute T Cell-mediated Rejection.

Transplantation

Avec: Franco B Mueller , Hua Yang , Carol Li , Darshana M Dadhania , Jenny Z Xiang , Steven P Salvatore , Surya V Seshan , Vijay K Sharma , Manikkam Suthanthiran , Thangamani Muthukumar

Réseau de co-auteurs

Thangamani Muthukumar 20 collaborations

Darshana M Dadhania 19 collaborations

John R Lee 16 collaborations

Carol Li 15 collaborations

Vijay K Sharma 12 collaborations

Iwijn De Vlaminck 10 collaborations

Michelle Lubetzky 9 collaborations

Catherine Snopkowski 9 collaborations

Thalia Salinas 8 collaborations

Hua Yang 7 collaborations

Surya V Seshan 7 collaborations

Ruchuang Ding 7 collaborations

Darshana Dadhania 7 collaborations

Franco B Mueller 6 collaborations

Karsten Suhre 6 collaborations

Divya Shankaranarayanan 5 collaborations

Steven P Salvatore 5 collaborations

Jenny Z Xiang 5 collaborations

John Richard Lee 5 collaborations

Alexandre Pellan Cheng 5 collaborations

Olivier Elemento 4 collaborations

Matthew Magruder 4 collaborations

Shady Albakry 4 collaborations

Emmanuel Edusei 4 collaborations

Adrienne Chang 4 collaborations

Omary Mzava 4 collaborations

Philip Burnham 4 collaborations

Michael J Satlin 4 collaborations

Akanksha Verma 3 collaborations

Ying Taur 3 collaborations

Amy Steadman 3 collaborations

Mila Lagman 3 collaborations

Khaled Machaca 3 collaborations

Lars F Westblade 3 collaborations

Joan Sesing Lenz 3 collaborations

Joseph E Schwartz 3 collaborations

Jennifer Huang 2 collaborations

Lisa T Zhang 2 collaborations

Catherine Gong 2 collaborations

Adam N Sholi 2 collaborations

Eric G Pamer 2 collaborations

Jun B Lee 2 collaborations

Choli Hartono 2 collaborations

Madhav Mantri 2 collaborations

Lisa Zhang 2 collaborations

Amy Robertson 2 collaborations

Carl Crawford 2 collaborations

Lilan Ling 2 collaborations

Eric Pamer 2 collaborations

Thomas Tuschl 2 collaborations

Gabriel Stryjniak 2 collaborations

Liz-Audrey Kounatse Djomnang 2 collaborations

Gaurav Thareja 2 collaborations

Aziz Belkadi 2 collaborations

Sami Smalling 2 collaborations

Randy Longman 2 collaborations

Mirella Salvatore 2 collaborations

Christopher E Mason 2 collaborations

Michael F Cassidy 1 collaboration

Joan S Lenz 1 collaboration

Alexandre P Cheng 1 collaboration

S Timothy Motley 1 collaboration

Crissa Bennett 1 collaboration

John T Connelly 1 collaboration

Essa Abuhelaiqa 1 collaboration

Steve Salvatore 1 collaboration

Zahraa Khan 1 collaboration

Jonas Schluter 1 collaboration

Meredith J Aull 1 collaboration

Rebecca Craig-Schapiro 1 collaboration

Jehona Marku-Podvorica 1 collaboration

Laura Gingras 1 collaboration

Samuel Sultan 1 collaboration

Rosy Priya Kodiyanplakkal 1 collaboration

Stuart Saal 1 collaboration

Sandip Kapur 1 collaboration

Joseph R Leventhal 1 collaboration

John Galvin 1 collaboration

Michael G Ison 1 collaboration

Chris Yuhsuen Feng 1 collaboration

James M Mathew 1 collaboration

Lorenzo Gallon 1 collaboration

Meg Gibson 1 collaboration

Dianne Belshe 1 collaboration

David J Tollerud 1 collaboration

Eric Gornstein 1 collaboration

Suzanne T Ildstad 1 collaboration

Nardhy Gomez-Lopez 1 collaboration

Michael Heyang 1 collaboration

Roberto Romero 1 collaboration

Matthew Pellan Cheng 1 collaboration

Kemal M Akat 1 collaboration

Heejung Bang 1 collaboration

Iddo Z Ben-Dov 1 collaboration

David Ikle 1 collaboration

Anthony J Demetris 1 collaboration

Prabhakar Putheti 1 collaboration

Rex Friedlander 1 collaboration

Arvind Menon 1 collaboration

Clayton Hughes 1 collaboration

Joseph Schwartz 1 collaboration

Yajas Shah 1 collaboration

Shab E Gul Rahim 1 collaboration

Elly Varma 1 collaboration

Steven Salvatore 1 collaboration

Michelle L Lubetzky 1 collaboration

Danny Luan 1 collaboration

Phyllis August 1 collaboration

Brittany Botticelli 1 collaboration

Tricia Alston 1 collaboration

Kevin Chan 1 collaboration

Qiuying Chen 1 collaboration

Steven S Gross 1 collaboration

Hemant Suryawanshi 1 collaboration

Pavel Morozov 1 collaboration

Alicia Alonso 1 collaboration

Juhi Kumar 1 collaboration

Kévin Contrepois 1 collaboration

Michael Snyder 1 collaboration

Paul C Grimm 1 collaboration

Asha Moudgil 1 collaboration

Jodi M Smith 1 collaboration

Amy E Bobrowski 1 collaboration

Priya S Verghese 1 collaboration

David Hooper 1 collaboration

Elizabeth Ingulli 1 collaboration

Rachel Lestz 1 collaboration

Patricia Weng 1 collaboration

Janaiya L Reason 1 collaboration

Tom D Blydt-Hansen 1 collaboration

Brendan Keating 1 collaboration

Sandra Amaral 1 collaboration

Fang Yu 1 collaboration

Raphael Courjaret 1 collaboration

Asha Elmi 1 collaboration

Ethel Alcantara Adap 1 collaboration

Nelson N Orie 1 collaboration

Fawzi Zghyer 1 collaboration

Satanay Hubrack 1 collaboration

Sajad Hayat 1 collaboration

Nidal Asaad 1 collaboration

Stefan Worgall 1 collaboration

Vidya Mohamed Ali 1 collaboration

Hanbo Dong 1 collaboration

Runzhe Li 1 collaboration

Ni Zhao 1 collaboration

Wodan Ling 1 collaboration

Bryan J Dooley 1 collaboration

Michele Lubetzky 1 collaboration

Eric Littman 1 collaboration

Liz-Audrey Djomnang Kounatse 1 collaboration

Joan Lenz 1 collaboration

Anna Halama 1 collaboration

Sara Abdelkader 1 collaboration

Silvana Abdulla 1 collaboration

Yasmin Mahmoud 1 collaboration

Joel Malek 1 collaboration

Vijay Sharma 1 collaboration

Luis G Gómez-Escobar 1 collaboration

Edward J Schenck 1 collaboration