Maria Musgaard

Affiliations

Department of Biochemistry, University of Oxford, Oxford, United Kingdom.
Present address: OMass Therapeutics, Oxford, United Kingdom.

Publications (15)

Small-molecule positive allosteric modulation of homomeric kainate receptors GluK1-3: development of screening assays and insight into GluK3 structure.

The FEBS journal

Avec: Yasmin Bay , Raminta Venskutonytė , Stine M Frantsen , Thor S Thorsen , Maria Musgaard , Karla Frydenvang , Pierre Francotte , Bernard Pirotte , Philip C Biggin , Anders S Kristensen , Thomas Boesen , Darryl S Pickering , Michael Gajhede , Jette S Kastrup

Identification and functional evaluation of GRIA1 missense and truncation variants in individuals with ID: An emerging neurodevelopmental syndrome.

American journal of human genetics

Avec: Vardha Ismail , Linda G Zachariassen , Annie Godwin , Mane Sahakian , Sian Ellard , Karen L Stals , Emma Baple , Kate Tatton Brown , Nicola Foulds , Gabrielle Wheway , Matthew O Parker , Signe M Lyngby , Miriam G Pedersen , Julie Desir , Allan Bayat , Maria Musgaard , Matthew Guille , Anders S Kristensen , Diana Baralle

Identification of compounds that bind the centriolar protein SAS-6 and inhibit its oligomerization.

The Journal of biological chemistry

Avec: Julia M C Busch , Minos-Timotheos Matsoukas , Maria Musgaard , Georgios A Spyroulias , Philip C Biggin , Ioannis Vakonakis

A dynamically interacting flexible loop assists oligomerisation of the Caenorhabditis elegans centriolar protein SAS-6.

Scientific reports

Avec: Julia M C Busch , Michèle C Erat , Iris D Blank , Maria Musgaard , Philip C Biggin , Ioannis Vakonakis

Multiscale molecular dynamics simulations predict arachidonic acid binding sites in human ASIC1a and ASIC3 transmembrane domains.

The Journal of general physiology

Avec: Anna Ananchenko , Maria Musgaard

Coupling structure with function in acid-sensing ion channels: challenges in pursuit of proton sensors.

The Journal of physiology

Avec: Matthew L Rook , Maria Musgaard , David M MacLean

β11-12 linker isomerization governs acid-sensing ion channel desensitization and recovery.

eLife

Avec: Matthew L Rook , Abby Williamson , John D Lueck , Maria Musgaard , David M Maclean

A single historical substitution drives an increase in acetylcholine receptor complexity.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Johnathon R Emlaw , Christian J G Tessier , Gregory D McCluskey , Melissa S McNulty , Yusuf Sheikh , Kelly M Burkett , Maria Musgaard , Corrie J B daCosta

Statin activation of skeletal ryanodine receptors (RyR1) is a class effect but separable from HMG-CoA reductase inhibition.

British journal of pharmacology

Avec: Chris Lindsay , Maria Musgaard , Angela J Russell , Rebecca Sitsapesan

Gain-of-function and loss-of-function variants in GRIA3 lead to distinct neurodevelopmental phenotypes.

Brain : a journal of neurology

Avec: Berardo Rinaldi , Allan Bayat , Linda G Zachariassen , Jia-Hui Sun , Yu-Han Ge , Dan Zhao , Kristine Bonde , Laura H Madsen , Ilham Abdimunim Ali Awad , Duygu Bagiran , Amal Sbeih , Syeda Maidah Shah , Shaymaa El-Sayed , Signe M Lyngby , Miriam G Pedersen , Charlotte Stenum-Berg , Louise Claudia Walker , Ilona Krey , Andrée Delahaye-Duriez , Lisa T Emrick , Krystal Sully , Chaya N Murali , Lindsay C Burrage , Julie Ana Plaud Gonzalez , Mered Parnes , Jennifer Friedman , Bertrand Isidor , Jérémie Lefranc , Sylvia Redon , Delphine Heron , Cyril Mignot , Boris Keren , Mélanie Fradin , Christele Dubourg , Sandra Mercier , Thomas Besnard , Benjamin Cogne , Wallid Deb , Clotilde Rivier , Donatella Milani , Maria Francesca Bedeschi , Claudia Di Napoli , Federico Grilli , Paola Marchisio , Suzanna Koudijs , Danielle Veenma , Emanuela Argilli , Sally Ann Lynch , Ping Yee Billie Au , Fernando Eduardo Ayala Valenzuela , Carolyn Brown , Diane Masser-Frye , Marilyn Jones , Leslie Patron Romero , Wenhui Laura Li , Erin Thorpe , Laura Hecher , Jessika Johannsen , Jonas Denecke , Vanda McNiven , Anna Szuto , Emma Wakeling , Vincent Cruz , Valerie Sency , Heng Wang , Juliette Piard , Fanny Kortüm , Theresia Herget , Tatjana Bierhals , Angelo Condell , Bruria Ben Zeev , Simranpreet Kaur , John Christodoulou , Amelie Piton , Christiane Zweier , Cornelia Kraus , Alessia Micalizzi , Marina Trivisano , Nicola Specchio , Gaetan Lesca , Rikke S Møller , Zeynep Tümer , Maria Musgaard , Benedicte Gerard , Johannes R Lemke , Yun Stone Shi , Anders S Kristensen

Mutational Analysis and Modeling of Negative Allosteric Modulator Binding Sites in AMPA Receptors.

Molecular pharmacology

Avec: Charlotte Stenum-Berg , Maria Musgaard , Sergei Chavez-Abiega , Christine L Thisted , Lorenzo Barrella , Philip C Biggin , Anders S Kristensen

The V2475F CPVT1 mutation yields distinct RyR2 channel populations that differ in their responses to cytosolic Ca

The Journal of physiology

Avec: Abigail D Wilson , Jianshu Hu , Charalampos Sigalas , Elisa Venturi , Héctor H Valdivia , Carmen R Valdivia , Ming Lei , Maria Musgaard , Rebecca Sitsapesan

Mutation of a conserved glutamine residue does not abolish desensitization of acid-sensing ion channel 1.

The Journal of general physiology

Avec: Matthew L Rook , Megan Miaro , Tyler Couch , Dana L Kneisley , Maria Musgaard , David M MacLean

Molecular Investigation of Chicken Acid-Sensing Ion Channel 1 β11-12 Linker Isomerization and Channel Kinetics.

Frontiers in cellular neuroscience

Avec: Matthew L Rook , Anna Ananchenko , Maria Musgaard , David M MacLean

Ligand-induced conformational changes in the β1-adrenergic receptor revealed by hydrogen-deuterium exchange mass spectrometry.

Nature communications

Avec: Joanna Toporowska , Parth Kapoor , Maria Musgaard , Karolina Gherbi , Kathy Sengmany , Feng Qu , Mark Soave , Hsin-Yung Yen , Kjetil Hansen , Ali Jazayeri , Jonathan T S Hopper , Argyris Politis

Réseau de co-auteurs

Philip C Biggin 4 collaborations

Anders S Kristensen 4 collaborations

Matthew L Rook 4 collaborations

David M MacLean 3 collaborations

Linda G Zachariassen 2 collaborations

Signe M Lyngby 2 collaborations

Miriam G Pedersen 2 collaborations

Allan Bayat 2 collaborations

Julia M C Busch 2 collaborations

Ioannis Vakonakis 2 collaborations

Anna Ananchenko 2 collaborations

Rebecca Sitsapesan 2 collaborations

Charlotte Stenum-Berg 2 collaborations

Yasmin Bay 1 collaboration

Raminta Venskutonytė 1 collaboration

Stine M Frantsen 1 collaboration

Thor S Thorsen 1 collaboration

Karla Frydenvang 1 collaboration

Pierre Francotte 1 collaboration

Bernard Pirotte 1 collaboration

Thomas Boesen 1 collaboration

Darryl S Pickering 1 collaboration

Michael Gajhede 1 collaboration

Jette S Kastrup 1 collaboration

Vardha Ismail 1 collaboration

Annie Godwin 1 collaboration

Mane Sahakian 1 collaboration

Sian Ellard 1 collaboration

Karen L Stals 1 collaboration

Emma Baple 1 collaboration

Kate Tatton Brown 1 collaboration

Nicola Foulds 1 collaboration

Gabrielle Wheway 1 collaboration

Matthew O Parker 1 collaboration

Julie Desir 1 collaboration

Matthew Guille 1 collaboration

Diana Baralle 1 collaboration

Minos-Timotheos Matsoukas 1 collaboration

Georgios A Spyroulias 1 collaboration

Michèle C Erat 1 collaboration

Iris D Blank 1 collaboration

Abby Williamson 1 collaboration

John D Lueck 1 collaboration

David M Maclean 1 collaboration

Johnathon R Emlaw 1 collaboration

Christian J G Tessier 1 collaboration

Gregory D McCluskey 1 collaboration

Melissa S McNulty 1 collaboration

Yusuf Sheikh 1 collaboration

Kelly M Burkett 1 collaboration

Corrie J B daCosta 1 collaboration

Chris Lindsay 1 collaboration

Angela J Russell 1 collaboration

Berardo Rinaldi 1 collaboration

Jia-Hui Sun 1 collaboration

Yu-Han Ge 1 collaboration

Dan Zhao 1 collaboration

Kristine Bonde 1 collaboration

Laura H Madsen 1 collaboration

Ilham Abdimunim Ali Awad 1 collaboration

Duygu Bagiran 1 collaboration

Amal Sbeih 1 collaboration

Syeda Maidah Shah 1 collaboration

Shaymaa El-Sayed 1 collaboration

Louise Claudia Walker 1 collaboration

Ilona Krey 1 collaboration

Andrée Delahaye-Duriez 1 collaboration

Lisa T Emrick 1 collaboration

Krystal Sully 1 collaboration

Chaya N Murali 1 collaboration

Lindsay C Burrage 1 collaboration

Julie Ana Plaud Gonzalez 1 collaboration

Mered Parnes 1 collaboration

Jennifer Friedman 1 collaboration

Bertrand Isidor 1 collaboration

Jérémie Lefranc 1 collaboration

Sylvia Redon 1 collaboration

Delphine Heron 1 collaboration

Cyril Mignot 1 collaboration

Boris Keren 1 collaboration

Mélanie Fradin 1 collaboration

Christele Dubourg 1 collaboration

Sandra Mercier 1 collaboration

Thomas Besnard 1 collaboration

Benjamin Cogne 1 collaboration

Wallid Deb 1 collaboration

Clotilde Rivier 1 collaboration

Donatella Milani 1 collaboration

Maria Francesca Bedeschi 1 collaboration

Claudia Di Napoli 1 collaboration

Federico Grilli 1 collaboration

Paola Marchisio 1 collaboration

Suzanna Koudijs 1 collaboration

Danielle Veenma 1 collaboration

Emanuela Argilli 1 collaboration

Sally Ann Lynch 1 collaboration

Ping Yee Billie Au 1 collaboration

Fernando Eduardo Ayala Valenzuela 1 collaboration

Carolyn Brown 1 collaboration

Diane Masser-Frye 1 collaboration

Marilyn Jones 1 collaboration

Leslie Patron Romero 1 collaboration

Wenhui Laura Li 1 collaboration

Erin Thorpe 1 collaboration

Laura Hecher 1 collaboration

Jessika Johannsen 1 collaboration

Jonas Denecke 1 collaboration

Vanda McNiven 1 collaboration

Anna Szuto 1 collaboration

Emma Wakeling 1 collaboration

Vincent Cruz 1 collaboration

Valerie Sency 1 collaboration

Heng Wang 1 collaboration

Juliette Piard 1 collaboration

Fanny Kortüm 1 collaboration

Theresia Herget 1 collaboration

Tatjana Bierhals 1 collaboration

Angelo Condell 1 collaboration

Bruria Ben Zeev 1 collaboration

Simranpreet Kaur 1 collaboration

John Christodoulou 1 collaboration

Amelie Piton 1 collaboration

Christiane Zweier 1 collaboration

Cornelia Kraus 1 collaboration

Alessia Micalizzi 1 collaboration

Marina Trivisano 1 collaboration

Nicola Specchio 1 collaboration

Gaetan Lesca 1 collaboration

Rikke S Møller 1 collaboration

Zeynep Tümer 1 collaboration

Benedicte Gerard 1 collaboration

Johannes R Lemke 1 collaboration

Yun Stone Shi 1 collaboration

Sergei Chavez-Abiega 1 collaboration

Christine L Thisted 1 collaboration

Lorenzo Barrella 1 collaboration

Abigail D Wilson 1 collaboration

Jianshu Hu 1 collaboration

Charalampos Sigalas 1 collaboration

Elisa Venturi 1 collaboration

Héctor H Valdivia 1 collaboration

Carmen R Valdivia 1 collaboration

Ming Lei 1 collaboration

Megan Miaro 1 collaboration

Tyler Couch 1 collaboration

Dana L Kneisley 1 collaboration

Joanna Toporowska 1 collaboration

Parth Kapoor 1 collaboration

Karolina Gherbi 1 collaboration

Kathy Sengmany 1 collaboration

Feng Qu 1 collaboration

Mark Soave 1 collaboration

Hsin-Yung Yen 1 collaboration

Kjetil Hansen 1 collaboration

Ali Jazayeri 1 collaboration

Jonathan T S Hopper 1 collaboration

Argyris Politis 1 collaboration