Matthew Kulke

Affiliations

Division of Hematology Oncology, Department of Medicine, Boston University School of Medicine, Boston, MA.

Publications (26)

Multicohort Retrospective Validation of a Predictive Biomarker for Topoisomerase I Inhibitors.

Clinical colorectal cancer

Avec: Koji Ando , Al Ozonoff , Shin-Yin Lee , Michael Voisine , Julian-Taylor Parker , Ryota Nakanishi , Sho Nishimura , Jing Yang , Zhao Grace , Ben Tran , Thomas J Diefenbach , Yoshihiko Maehara , Hiroshi Yasui , Tomoyuki Irino , Ravi Salgia , Masanori Terashima , Peter Gibbs , Ramesh K Ramanathan , Eiji Oki , Masaki Mori , Matthew Kulke , Kevan Hartshorn , Ajit Bharti

Replica-Based Protein Structure Sampling Methods II: Advanced Hybrid Solvent TIGER2hs.

The journal of physical chemistry. B

Avec: Norman Geist , Martin Kulke , Lukas Schulig , Andreas Link , Walter Langel

Reversible Unwrapping Algorithm for Constant-Pressure Molecular Dynamics Simulations.

Journal of chemical theory and computation

Avec: Martin Kulke , Josh V Vermaas

Long-Range Electron Transport Rates Depend on Wire Dimensions in Cytochrome Nanowires.

Small (Weinheim an der Bergstrasse, Germany)

Avec: Martin Kulke , Dayna M Olson , Jingcheng Huang , David M Kramer , Josh V Vermaas

Specific domain V reduction of beta-2-glycoprotein I induces protein flexibility and alters pathogenic antibody binding.

Scientific reports

Avec: Ina Buchholz , Thomas McDonnell , Peter Nestler , Sudarat Tharad , Martin Kulke , Anna Radziszewska , Vera M Ripoll , Frank Schmidt , Elke Hammer , Jose L Toca-Herrera , Anisur Rahman , Mihaela Delcea

Identification of a HTT-specific binding motif in DNAJB1 essential for suppression and disaggregation of HTT.

Nature communications

Avec: S M Ayala Mariscal , M L Pigazzini , Y Richter , M Özel , I L Grothaus , J Protze , K Ziege , M Kulke , M ElBediwi , J V Vermaas , L Colombi Ciacchi , S Köppen , F Liu , J Kirstein

Nanoscale simulation of the thylakoid membrane response to extreme temperatures.

Plant, cell & environment

Avec: Martin Kulke , Sarathi M Weraduwage , Thomas D Sharkey , Josh V Vermaas

Phosphorylation of Fibronectin Influences the Structural Stability of the Predicted Interchain Domain.

Journal of chemical information and modeling

Avec: Martin Kulke , Myriam Uhrhan , Norman Geist , Dorothea Brüggemann , Bastian Ohler , Walter Langel , Susan Köppen

Evaluation of meaningful change in bowel movement frequency for patients with carcinoid syndrome.

Journal of patient-reported outcomes

Avec: Stacie Hudgens , John Ramage , Matthew Kulke , Emily Bergsland , Lowell Anthony , Martyn Caplin , Kjell Öberg , Marianne Pavel , Jonathon Gable , Phillip Banks , Qi Melissa Yang , Pablo Lapuerta

Weight Maintenance up to 48 Weeks in Patients With Carcinoid Syndrome Treated With Telotristat Ethyl: Pooled Data From the Open-Label Extensions of the Phase III Clinical Trials TELESTAR and TELECAST.

Clinical therapeutics

Avec: Rajaventhan Srirajaskanthan , Marianne Pavel , Matthew Kulke , Dominique Clement , Aude Houchard , Lucie Keeber , Martin O Weickert

Recurrence Patterns After Surgical Resection of Gastroenteropancreatic Neuroendocrine Tumors: Analysis From the National Comprehensive Cancer Network Oncology Outcomes Database.

Pancreas

Avec: Hilary Chan , Li Zhang , Michael A Choti , Matthew Kulke , James C Yao , Eric K Nakakura , Mark Bloomston , Al B Benson , Manisha H Shah , Jonathan R Strosberg , Emily K Bergsland , Katherine Van Loon

Fundamental Redesign of the TIGER2hs Kernel to Address Severe Parameter Sensitivity.

Journal of chemical information and modeling

Avec: Lukas Schulig , Norman Geist , Mihaela Delcea , Andreas Link , Martin Kulke

Site-specific modification of native IgGs with flexible drug-load.

Chembiochem : a European journal of chemical biology

Avec: Jöri E Wehrmüller , Julia C Frei , Torsten Hechler , Michael Kulke , Andreas Pahl , Martin Béhé , Roger Schibli , Philipp R Spycher

Unveiling the N-Terminal Homodimerization of BCL11B by Hybrid Solvent Replica-Exchange Simulations.

International journal of molecular sciences

Avec: Lukas Schulig , Piotr Grabarczyk , Norman Geist , Martin Delin , Hannes Forkel , Martin Kulke , Mihaela Delcea , Christian A Schmidt , Andreas Link

HDP-101, an Anti-BCMA Antibody-Drug Conjugate, Safely Delivers Amanitin to Induce Cell Death in Proliferating and Resting Multiple Myeloma Cells.

Molecular cancer therapeutics

Avec: Vianihuini Figueroa-Vazquez , Jonathan Ko , Christian Breunig , Anja Baumann , Nicola Giesen , Anikó Pálfi , Christoph Müller , Christian Lutz , Torsten Hechler , Michael Kulke , Carsten Müller-Tidow , Alwin Krämer , Hartmut Goldschmidt , Andreas Pahl , Marc S Raab

Characterization of promoter elements of isoprene-responsive genes and the ability of isoprene to bind START domain transcription factors.

Plant direct

Avec: Sarathi M Weraduwage , Abira Sahu , Martin Kulke , Josh V Vermaas , Thomas D Sharkey

Electron transfer in a crystalline cytochrome with four hemes.

The Journal of chemical physics

Avec: William W Parson , Jingcheng Huang , Martin Kulke , Josh V Vermaas , David M Kramer

Diagnosis and Management of Parathyroid Carcinoma.

Clinical pharmacology and therapeutics

Avec: Alexander Lazzaro , Grace Qing Zhao , Matthew Kulke

Molecular dynamics simulations to the bidirectional adhesion signaling pathway of integrin α

Proteins

Avec: Martin Kulke , Walter Langel

Drug-induced activation of integrin alpha IIb beta 3 leads to minor localized structural changes.

PloS one

Avec: Una Janke , Martin Kulke , Ina Buchholz , Norman Geist , Walter Langel , Mihaela Delcea

Targeted immunotherapy for HER2-low breast cancer with 17p loss.

Science translational medicine

Avec: Yujing Li , Yifan Sun , Michael Kulke , Torsten Hechler , Kevin Van der Jeught , Tianhan Dong , Bin He , Kathy D Miller , Milan Radovich , Bryan P Schneider , Andreas Pahl , Xinna Zhang , Xiongbin Lu

Updated Efficacy and Safety Outcomes for Patients with Well-Differentiated Pancreatic Neuroendocrine Tumors Treated with Sunitinib.

Targeted oncology

Avec: Nicola Fazio , Matthew Kulke , Brad Rosbrook , Kathrine Fernandez , Eric Raymond

A Hypothesized Mechanism for Chronic Pancreatitis Caused by the N34S Mutation of Serine Protease Inhibitor Kazal-Type 1 Based on Conformational Studies.

Journal of inflammation research

Avec: Martin Kulke , Felix Nagel , Lukas Schulig , Norman Geist , Marcel Gabor , Julia Mayerle , Markus M Lerch , Andreas Link , Mihaela Delcea

LongBondEliminator: A Molecular Simulation Tool to Remove Ring Penetrations in Biomolecular Simulation Systems.

Biomolecules

Avec: Daipayan Sarkar , Martin Kulke , Josh V Vermaas

PLAT domain protein 1 (PLAT1/PLAFP) binds to the Arabidopsis thaliana plasma membrane and inserts a lipid.

Plant science : an international journal of experimental plant biology

Avec: Martin Kulke , Evan Kurtz , Duncan M Boren , Dayna M Olson , Amanda M Koenig , Susanne Hoffmann-Benning , Josh V Vermaas

The isoprene-responsive phosphoproteome provides new insights into the putative signalling pathways and novel roles of isoprene.

Plant, cell & environment

Avec: Sarathi M Weraduwage , Douglas Whitten , Martin Kulke , Abira Sahu , Josh V Vermaas , Thomas D Sharkey

Réseau de co-auteurs

Martin Kulke 16 collaborations

Josh V Vermaas 8 collaborations

Norman Geist 6 collaborations

Mihaela Delcea 5 collaborations

Lukas Schulig 4 collaborations

Andreas Link 4 collaborations

Walter Langel 4 collaborations

Sarathi M Weraduwage 3 collaborations

Thomas D Sharkey 3 collaborations

Torsten Hechler 3 collaborations

Michael Kulke 3 collaborations

Andreas Pahl 3 collaborations

Dayna M Olson 2 collaborations

Jingcheng Huang 2 collaborations

David M Kramer 2 collaborations

Ina Buchholz 2 collaborations

Marianne Pavel 2 collaborations

Abira Sahu 2 collaborations

Koji Ando 1 collaboration

Al Ozonoff 1 collaboration

Shin-Yin Lee 1 collaboration

Michael Voisine 1 collaboration

Julian-Taylor Parker 1 collaboration

Ryota Nakanishi 1 collaboration

Sho Nishimura 1 collaboration

Jing Yang 1 collaboration

Zhao Grace 1 collaboration

Ben Tran 1 collaboration

Thomas J Diefenbach 1 collaboration

Yoshihiko Maehara 1 collaboration

Hiroshi Yasui 1 collaboration

Tomoyuki Irino 1 collaboration

Ravi Salgia 1 collaboration

Masanori Terashima 1 collaboration

Peter Gibbs 1 collaboration

Ramesh K Ramanathan 1 collaboration

Eiji Oki 1 collaboration

Masaki Mori 1 collaboration

Kevan Hartshorn 1 collaboration

Ajit Bharti 1 collaboration

Thomas McDonnell 1 collaboration

Peter Nestler 1 collaboration

Sudarat Tharad 1 collaboration

Anna Radziszewska 1 collaboration

Vera M Ripoll 1 collaboration

Frank Schmidt 1 collaboration

Elke Hammer 1 collaboration

Jose L Toca-Herrera 1 collaboration

Anisur Rahman 1 collaboration

S M Ayala Mariscal 1 collaboration

M L Pigazzini 1 collaboration

Y Richter 1 collaboration

M Özel 1 collaboration

I L Grothaus 1 collaboration

J Protze 1 collaboration

K Ziege 1 collaboration

M Kulke 1 collaboration

M ElBediwi 1 collaboration

J V Vermaas 1 collaboration

L Colombi Ciacchi 1 collaboration

S Köppen 1 collaboration

F Liu 1 collaboration

J Kirstein 1 collaboration

Myriam Uhrhan 1 collaboration

Dorothea Brüggemann 1 collaboration

Bastian Ohler 1 collaboration

Susan Köppen 1 collaboration

Stacie Hudgens 1 collaboration

John Ramage 1 collaboration

Emily Bergsland 1 collaboration

Lowell Anthony 1 collaboration

Martyn Caplin 1 collaboration

Kjell Öberg 1 collaboration

Jonathon Gable 1 collaboration

Phillip Banks 1 collaboration

Qi Melissa Yang 1 collaboration

Pablo Lapuerta 1 collaboration

Rajaventhan Srirajaskanthan 1 collaboration

Dominique Clement 1 collaboration

Aude Houchard 1 collaboration

Lucie Keeber 1 collaboration

Martin O Weickert 1 collaboration

Hilary Chan 1 collaboration

Li Zhang 1 collaboration

Michael A Choti 1 collaboration

James C Yao 1 collaboration

Eric K Nakakura 1 collaboration

Mark Bloomston 1 collaboration

Al B Benson 1 collaboration

Manisha H Shah 1 collaboration

Jonathan R Strosberg 1 collaboration

Emily K Bergsland 1 collaboration

Katherine Van Loon 1 collaboration

Jöri E Wehrmüller 1 collaboration

Julia C Frei 1 collaboration

Martin Béhé 1 collaboration

Roger Schibli 1 collaboration

Philipp R Spycher 1 collaboration

Piotr Grabarczyk 1 collaboration

Martin Delin 1 collaboration

Hannes Forkel 1 collaboration

Christian A Schmidt 1 collaboration

Vianihuini Figueroa-Vazquez 1 collaboration

Jonathan Ko 1 collaboration

Christian Breunig 1 collaboration

Anja Baumann 1 collaboration

Nicola Giesen 1 collaboration

Anikó Pálfi 1 collaboration

Christoph Müller 1 collaboration

Christian Lutz 1 collaboration

Carsten Müller-Tidow 1 collaboration

Alwin Krämer 1 collaboration

Hartmut Goldschmidt 1 collaboration

Marc S Raab 1 collaboration

William W Parson 1 collaboration

Alexander Lazzaro 1 collaboration

Grace Qing Zhao 1 collaboration

Una Janke 1 collaboration

Yujing Li 1 collaboration

Yifan Sun 1 collaboration

Kevin Van der Jeught 1 collaboration

Tianhan Dong 1 collaboration

Bin He 1 collaboration

Kathy D Miller 1 collaboration

Milan Radovich 1 collaboration

Bryan P Schneider 1 collaboration

Xinna Zhang 1 collaboration

Xiongbin Lu 1 collaboration

Nicola Fazio 1 collaboration

Brad Rosbrook 1 collaboration

Kathrine Fernandez 1 collaboration

Eric Raymond 1 collaboration

Felix Nagel 1 collaboration

Marcel Gabor 1 collaboration

Julia Mayerle 1 collaboration

Markus M Lerch 1 collaboration

Daipayan Sarkar 1 collaboration

Evan Kurtz 1 collaboration

Duncan M Boren 1 collaboration

Amanda M Koenig 1 collaboration

Susanne Hoffmann-Benning 1 collaboration

Douglas Whitten 1 collaboration