Megerditch Kiledjian

Affiliations

Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, New Jersey, USA. Electronic address: kiledjian@biology.rutgers.edu.

Publications (12)

Recent insights into noncanonical 5' capping and decapping of RNA.

The Journal of biological chemistry

Avec: Selom K Doamekpor , Sunny Sharma , Megerditch Kiledjian , Liang Tong

mRNA-Decapping Associated DcpS Enzyme Controls Critical Steps of Neuronal Development.

Cerebral cortex (New York, N.Y. : 1991)

Avec: Iva Salamon , Geeta Palsule , Xiaobing Luo , Alfonso Roque , Shawn Tucai , Ishan Khosla , Nicole Volk , Wendy Liu , Huijuan Cui , Valentina Dal Pozzo , Petronio Zalamea , Xinfu Jiao , Gabriella D'Arcangelo , Ronald P Hart , Mladen-Roko Rasin , Megerditch Kiledjian

Structural and mechanistic basis of mammalian Nudt12 RNA deNADding.

Nature chemical biology

Avec: Ewa Grudzien-Nogalska , Yixuan Wu , Xinfu Jiao , Huijuan Cui , Maria K Mateyak , Ronald P Hart , Liang Tong , Megerditch Kiledjian

SOD1 regulates ribosome biogenesis in KRAS mutant non-small cell lung cancer.

Nature communications

Avec: Xiaowen Wang , Hong Zhang , Russell Sapio , Jun Yang , Justin Wong , Xin Zhang , Jessie Y Guo , Sharon Pine , Holly Van Remmen , Hong Li , Eileen White , Chen Liu , Megerditch Kiledjian , Dimitri G Pestov , X F Steven Zheng

Preparation of RNAs with non-canonical 5' ends using novel di- and trinucleotide reagents for co-transcriptional capping.

Frontiers in molecular biosciences

Avec: Anaïs Depaix , Ewa Grudzien-Nogalska , Bartlomiej Fedorczyk , Megerditch Kiledjian , Jacek Jemielity , Joanna Kowalska

InsP

Proceedings of the National Academy of Sciences of the United States of America

Avec: Soumyadip Sahu , Zhenzhen Wang , Xinfu Jiao , Chunfang Gu , Nikolaus Jork , Christopher Wittwer , Xingyao Li , Sarah Hostachy , Dorothea Fiedler , Huanchen Wang , Henning J Jessen , Megerditch Kiledjian , Stephen B Shears

Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs.

Nucleic acids research

Avec: Sunny Sharma , Ewa Grudzien-Nogalska , Keith Hamilton , Xinfu Jiao , Jun Yang , Liang Tong , Megerditch Kiledjian

DXO/Rai1 enzymes remove 5'-end FAD and dephospho-CoA caps on RNAs.

Nucleic acids research

Avec: Selom K Doamekpor , Ewa Grudzien-Nogalska , Agnieszka Mlynarska-Cieslak , Joanna Kowalska , Megerditch Kiledjian , Liang Tong

Identification of a novel deFADding activity in human, yeast and bacterial 5' to 3' exoribonucleases.

Nucleic acids research

Avec: Sunny Sharma , Jun Yang , Selom K Doamekpor , Ewa Grudizen-Nogalska , Liang Tong , Megerditch Kiledjian

Xrn1 is a deNADding enzyme modulating mitochondrial NAD-capped RNA.

Nature communications

Avec: Sunny Sharma , Jun Yang , Ewa Grudzien-Nogalska , Jessica Shivas , Kelvin Y Kwan , Megerditch Kiledjian

Biallelic NUDT2 variants defective in mRNA decapping cause a neurodevelopmental disease.

Brain : a journal of neurology

Avec: Ralf A Husain , Xinfu Jiao , J Christopher Hennings , Jan Giesecke , Geeta Palsule , Stefanie Beck-Wödl , Dina Osmanović , Kathrine Bjørgo , Asif Mir , Muhammad Ilyas , Saad M Abbasi , Stephanie Efthymiou , Natalia Dominik , Reza Maroofian , Henry Houlden , Julia Rankin , Alistair T Pagnamenta , Marwan Nashabat , Waleed Altwaijri , Majid Alfadhel , Muhammad Umair , Ebtissal Khouj , William Reardon , Ayman W El-Hattab , Mohammed Mekki , Gunnar Houge , Christian Beetz , Peter Bauer , Audrey Putoux , Gaetan Lesca , Damien Sanlaville , Fowzan S Alkuraya , Robert W Taylor , Hans-Joachim Mentzel , Christian A Hübner , Peter Huppke , Ronald P Hart , Tobias B Haack , Megerditch Kiledjian , Ignacio Rubio

NADcapPro and circNC: methods for accurate profiling of NAD and non-canonical RNA caps in eukaryotes.

Communications biology

Avec: Sunny Sharma , Jun Yang , John Favate , Premal Shah , Megerditch Kiledjian

Réseau de co-auteurs

Sunny Sharma 5 collaborations

Liang Tong 5 collaborations

Xinfu Jiao 5 collaborations

Ewa Grudzien-Nogalska 5 collaborations

Jun Yang 5 collaborations

Selom K Doamekpor 3 collaborations

Ronald P Hart 3 collaborations

Geeta Palsule 2 collaborations

Huijuan Cui 2 collaborations

Joanna Kowalska 2 collaborations

Iva Salamon 1 collaboration

Xiaobing Luo 1 collaboration

Alfonso Roque 1 collaboration

Shawn Tucai 1 collaboration

Ishan Khosla 1 collaboration

Nicole Volk 1 collaboration

Wendy Liu 1 collaboration

Valentina Dal Pozzo 1 collaboration

Petronio Zalamea 1 collaboration

Gabriella D'Arcangelo 1 collaboration

Mladen-Roko Rasin 1 collaboration

Yixuan Wu 1 collaboration

Maria K Mateyak 1 collaboration

Xiaowen Wang 1 collaboration

Hong Zhang 1 collaboration

Russell Sapio 1 collaboration

Justin Wong 1 collaboration

Xin Zhang 1 collaboration

Jessie Y Guo 1 collaboration

Sharon Pine 1 collaboration

Holly Van Remmen 1 collaboration

Hong Li 1 collaboration

Eileen White 1 collaboration

Chen Liu 1 collaboration

Dimitri G Pestov 1 collaboration

X F Steven Zheng 1 collaboration

Anaïs Depaix 1 collaboration

Bartlomiej Fedorczyk 1 collaboration

Jacek Jemielity 1 collaboration

Soumyadip Sahu 1 collaboration

Zhenzhen Wang 1 collaboration

Chunfang Gu 1 collaboration

Nikolaus Jork 1 collaboration

Christopher Wittwer 1 collaboration

Xingyao Li 1 collaboration

Sarah Hostachy 1 collaboration

Dorothea Fiedler 1 collaboration

Huanchen Wang 1 collaboration

Henning J Jessen 1 collaboration

Stephen B Shears 1 collaboration

Keith Hamilton 1 collaboration

Agnieszka Mlynarska-Cieslak 1 collaboration

Ewa Grudizen-Nogalska 1 collaboration

Jessica Shivas 1 collaboration

Kelvin Y Kwan 1 collaboration

Ralf A Husain 1 collaboration

J Christopher Hennings 1 collaboration

Jan Giesecke 1 collaboration

Stefanie Beck-Wödl 1 collaboration

Dina Osmanović 1 collaboration

Kathrine Bjørgo 1 collaboration

Asif Mir 1 collaboration

Muhammad Ilyas 1 collaboration

Saad M Abbasi 1 collaboration

Stephanie Efthymiou 1 collaboration

Natalia Dominik 1 collaboration

Reza Maroofian 1 collaboration

Henry Houlden 1 collaboration

Julia Rankin 1 collaboration

Alistair T Pagnamenta 1 collaboration

Marwan Nashabat 1 collaboration

Waleed Altwaijri 1 collaboration

Majid Alfadhel 1 collaboration

Muhammad Umair 1 collaboration

Ebtissal Khouj 1 collaboration

William Reardon 1 collaboration

Ayman W El-Hattab 1 collaboration

Mohammed Mekki 1 collaboration

Gunnar Houge 1 collaboration

Christian Beetz 1 collaboration

Peter Bauer 1 collaboration

Audrey Putoux 1 collaboration

Gaetan Lesca 1 collaboration

Damien Sanlaville 1 collaboration

Fowzan S Alkuraya 1 collaboration

Robert W Taylor 1 collaboration

Hans-Joachim Mentzel 1 collaboration

Christian A Hübner 1 collaboration

Peter Huppke 1 collaboration

Tobias B Haack 1 collaboration

Ignacio Rubio 1 collaboration

John Favate 1 collaboration

Premal Shah 1 collaboration