Michelle Lockley

Affiliations

Centre for Cancer Genomics and Computational Biology, Barts Cancer Institute, Queen Mary University of London, London, UK.

Publications (25)

A multicentre retrospective cohort study of ovarian germ cell tumours: Evidence for chemotherapy de-escalation and alignment of paediatric and adult practice.

European journal of cancer (Oxford, England : 1990)

Avec: C Newton , K Murali , A Ahmad , H Hockings , R Graham , V Liberale , S-J Sarker , J Ledermann , D M Berney , J Shamash , S Banerjee , S Stoneham , M Lockley

A novel cell line panel reveals non-genetic mediators of platinum resistance and phenotypic diversity in high grade serous ovarian cancer.

Gynecologic oncology

Avec: J I Hoare , H Hockings , J Saxena , V L Silva , M J Haughey , G E Wood , F Nicolini , H Mirza , I A McNeish , W Huang , E Maniati , T A Graham , M Lockley

Extracellular matrix educates an immunoregulatory tumor macrophage phenotype found in ovarian cancer metastasis.

Nature communications

Avec: E H Puttock , E J Tyler , M Manni , E Maniati , C Butterworth , M Burger Ramos , E Peerani , P Hirani , V Gauthier , Y Liu , G Maniscalco , V Rajeeve , P Cutillas , C Trevisan , M Pozzobon , M Lockley , J Rastrick , H Läubli , A White , O M T Pearce

Adaptive therapy achieves long-term control of chemotherapy resistance in high grade ovarian cancer.

bioRxiv : the preprint server for biology

Avec: Helen Hockings , Eszter Lakatos , Weini Huang , Maximilian Mossner , Mohammed Ateeb Khan , Stephen Metcalf , Francesco Nicolini , Kane Smith , Ann-Marie Baker , Trevor A Graham , Michelle Lockley

Adolescent and Young Adult Germ Cell Tumors: Epidemiology, Genomics, Treatment, and Survivorship.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology

Avec: Lois B Travis , Darren R Feldman , Chunkit Fung , Jenny N Poynter , Michelle Lockley , A Lindsay Frazier

Comparison of overall and patterns of care in patients with a malignant ovarian germ cell tumor by age in the United States: a National Cancer Database (2004-2016) analysis.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Avec: Shannon M Sullivan , Sara Stoneham , Michelle Lockley , A Lindsay Frazier , Deborah F Billmire , Jenny N Poynter

Venous thromboembolism during neoadjuvant chemotherapy for ovarian cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Avec: Samuel Oxley , Sarah Ahmed , Kathryn Baxter , Dominic Blake , Victoria Braden , Mark R Brincat , Stacey Bryan , James Dilley , Stephen Dobbs , Andrew Durden , Nana Gomes , Ben Johnston , Sonali Kaushik , Fani Kokka , Michelle Lockley , Jack Lowe-Zinola , Ranjit Manchanda , Aiste McCormick , Charlotte Nott , Gemma Louise Owens , Aayushi Pandya , Jessica Prince , Neil Ryan , Nicole Ryan , Michail Sideris , Sameera Tanna , Justin Waters , Nathan Zamesa , Mari Thomas , Adeola Olaitan

Mainstreamed genetic testing for women with ovarian cancer: first-year experience.

Journal of medical genetics

Avec: Belinda Rahman , Anne Lanceley , Rebecca S Kristeleit , Jonathan A Ledermann , Michelle Lockley , Mary McCormack , Tim Mould , Lucy Side

Ovarian cancer in adolescents and young adults.

Pediatric blood & cancer

Avec: Michelle Lockley , Sara J Stoneham , Thomas A Olson

Pathological chemotherapy response score is prognostic in tubo-ovarian high-grade serous carcinoma: A systematic review and meta-analysis of individual patient data.

Gynecologic oncology

Avec: Paul A Cohen , Aime Powell , Steffen Böhm , C Blake Gilks , Colin J R Stewart , Tarek M Meniawy , Max Bulsara , Stefanie Avril , Eleanor C Brockbank , Tjalling Bosse , Gustavo Rubino de Azevedo Focchi , Raji Ganesan , Rosalind M Glasspool , Brooke E Howitt , Hyun-Soo Kim , Jung-Yun Lee , Nhu D Le , Michelle Lockley , Ranjit Manchanda , Trupti Mandalia , W Glenn McCluggage , Iain McNeish , Divya Midha , Radhika Srinivasan , Yun Yi Tan , Rachael van der Griend , Mayu Yunokawa , Gian F Zannoni , Auteur inconnu , Naveena Singh

Chloroxine overrides DNA damage tolerance to restore platinum sensitivity in high-grade serous ovarian cancer.

Cell death & disease

Avec: Vera L Silva , Jayeta Saxena , Francesco Nicolini , Joseph I Hoare , Stephen Metcalf , Sarah A Martin , Michelle Lockley

The avoiding late diagnosis of ovarian cancer (ALDO) project; a pilot national surveillance programme for women with pathogenic germline variants in

Journal of medical genetics

Avec: Sue Philpott , Maria Raikou , Ranjit Manchanda , Michelle Lockley , Naveena Singh , Malcolm Scott , D Gareth Evans , Julian Adlard , Munaza Ahmed , Richard Edmondson , Emma Roisin Woodward , Athena Lamnisos , Janos Balega , Angela F Brady , Aarti Sharma , Louise Izatt , Anjana Kulkarni , Vishakha Tripathi , Joyce S Solomons , Kevin Hayes , Helen Hanson , Katie Snape , Lucy Side , Steve Skates , Alistair McGuire , Adam N Rosenthal

Correction: Safety and utility of image-guided research biopsies in relapsed high-grade serous ovarian carcinoma-experience of the BriTROC consortium.

British journal of cancer

Avec: T Goranova , D Ennis , A M Piskorz , G Macintyre , L A Lewsley , J Stobo , C Wilson , D Kay , R M Glasspool , M Lockley , E Brockbank , A Montes , A Walther , S Sundar , R Edmondson , G D Hall , A Clamp , C Gourley , M Hall , C Fotopoulou , H Gabra , S Freeman , L Moore , M Jimenez-Linan , J Paul , J D Brenton , I A McNeish , Auteur inconnu

Histopathologic response to neoadjuvant chemotherapy as a prognostic biomarker in tubo-ovarian high-grade serous carcinoma: updated Chemotherapy Response Score (CRS) results.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Avec: Steffen Böhm , Nhu Le , Michelle Lockley , Elly Brockbank , Asma Faruqi , Ian Said , Arjun Jeyarajah , Rekha Wuntakal , Blake Gilks , Naveena Singh

Advancing clinical and translational research in germ cell tumours (GCT): recommendations from the Malignant Germ Cell International Consortium.

British journal of cancer

Avec: Adriana Fonseca , João Lobo , Florette K Hazard , Joanna Gell , Peter K Nicholls , Robert S Weiss , Lindsay Klosterkemper , Samuel L Volchenboum , James C Nicholson , A Lindsay Frazier , James F Amatruda , Aditya Bagrodia , Michelle Lockley , Matthew J Murray

Patient decision aids in mainstreaming genetic testing for women with ovarian cancer: A prospective cohort study.

BJOG : an international journal of obstetrics and gynaecology

Avec: Monika Sobocan , Dhivya Chandrasekaran , Michail Sideris , Oleg Blyuss , Caitlin Fierheller , Ashwin Kalra , Jacqueline Sia , Rowan E Miller , Tina Mills-Baldock , Shanthini M Crusz , Li Sun , Olivia Evans , Sadiyah Robbani , Lucy A Jenkins , Munaza Ahmed , Ajith Kumar , Mary Quigley , Michelle Lockley , Asma Faruqi , Laura Casey , Elly Brockbank , Saurabh Phadnis , Giorgia Trevisan , Naveena Singh , Rosa Legood , Ranjit Manchanda

Hearing preservation in paediatric cochlear implantation with the Nucleus Slim Straight Electrode - our experience.

International journal of audiology

Avec: Simone Schaefer , Mark Sladen , Jaya Nichani , Kerri Millward , Morag Lockley , Martin O'Driscoll , Karolina Kluk , Iain A Bruce

Single-agent carboplatin AUC10 in metastatic seminoma: A multi-centre UK study of 216 patients.

European journal of cancer (Oxford, England : 1990)

Avec: Constantine Alifrangis , Anand Sharma , Shafi Chowdhury , Sarah Duncan , Marina Milic , Andrew Gogbashian , Samita Agarwal , Anju Sahdev , Peter Wilson , Stephen Harland , Sara Stoneham , Michelle Lockley , Gordon Rustin , Timothy Oliver , Daniel Berney , Jonathan Shamash

Objective responses to first-line neoadjuvant carboplatin-paclitaxel regimens for ovarian, fallopian tube, or primary peritoneal carcinoma (ICON8): post-hoc exploratory analysis of a randomised, phase 3 trial.

The Lancet. Oncology

Avec: Robert D Morgan , Iain A McNeish , Adrian D Cook , Elizabeth C James , Rosemary Lord , Graham Dark , Rosalind M Glasspool , Jonathan Krell , Christine Parkinson , Christopher J Poole , Marcia Hall , Dolores Gallardo-Rincón , Michelle Lockley , Sharadah Essapen , Jeff Summers , Anjana Anand , Abel Zachariah , Sarah Williams , Rachel Jones , Kate Scatchard , Axel Walther , Jae-Weon Kim , Sudha Sundar , Gordon C Jayson , Jonathan A Ledermann , Andrew R Clamp

Ovarian germ cell tumour classification: views from the testis.

Histopathology

Avec: Daniel M Berney , Sara Stoneham , Rupali Arora , Jonathan Shamash , Michelle Lockley

Mainstreamed genetic testing in ovarian cancer: patient experience of the testing process.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society

Avec: Laura McLeavy , Belinda Rahman , Rebecca Kristeleit , Jonathan Ledermann , Michelle Lockley , Mary McCormack , Tim Mould , Lucy Side , Anne Lanceley

Implementation of Multigene Germline and Parallel Somatic Genetic Testing in Epithelial Ovarian Cancer: SIGNPOST Study.

Cancers

Avec: Dhivya Chandrasekaran , Monika Sobocan , Oleg Blyuss , Rowan E Miller , Olivia Evans , Shanthini M Crusz , Tina Mills-Baldock , Li Sun , Rory F L Hammond , Faiza Gaba , Lucy A Jenkins , Munaza Ahmed , Ajith Kumar , Arjun Jeyarajah , Alexandra C Lawrence , Elly Brockbank , Saurabh Phadnis , Mary Quigley , Fatima El Khouly , Rekha Wuntakal , Asma Faruqi , Giorgia Trevisan , Laura Casey , George J Burghel , Helene Schlecht , Michael Bulman , Philip Smith , Naomi L Bowers , Rosa Legood , Michelle Lockley , Andrew Wallace , Naveena Singh , D Gareth Evans , Ranjit Manchanda

LiquidCNA: Tracking subclonal evolution from longitudinal liquid biopsies using somatic copy number alterations.

iScience

Avec: Eszter Lakatos , Helen Hockings , Maximilian Mossner , Weini Huang , Michelle Lockley , Trevor A Graham

Surgical management and outcomes for stage 1 malignant ovarian germ cell tumours: A UK multicentre retrospective cohort study.

European journal of obstetrics, gynecology, and reproductive biology

Avec: Radha Graham , Nicola D MacDonald , Michelle Lockley , Rowan Miller , John Butler , Krithika Murali , Shah-Jalal Sarker , Susana Banerjee , Sara Stoneham , Jonathan Shamash , Viola Liberale , Daniel M Berney , Claire Newton

Cost-Effectiveness of Unselected Multigene Germline and Somatic Genetic Testing for Epithelial Ovarian Cancer.

Journal of the National Comprehensive Cancer Network : JNCCN

Avec: Ranjit Manchanda , Li Sun , Monika Sobocan , Isabel V Rodriguez , Xia Wei , Ashwin Kalra , Samuel Oxley , Michail Sideris , Caitlin T Fierheller , Robert D Morgan , Dhivya Chandrasekaran , Kelly Rust , Pavlina Spiliopoulou , Rowan E Miller , Shanthini M Crusz , Michelle Lockley , Naveena Singh , Asma Faruqi , Laura Casey , Elly Brockbank , Saurabh Phadnis , Tina Mills-Baldock , Fatima El-Khouly , Lucy A Jenkins , Andrew Wallace , Munaza Ahmed , Ajith Kumar , Elizabeth M Swisher , Charlie Gourley , Barbara M Norquist , D Gareth Evans , Rosa Legood

Réseau de co-auteurs

Ranjit Manchanda 6 collaborations

Naveena Singh 6 collaborations

M Lockley 4 collaborations

Sara Stoneham 4 collaborations

Munaza Ahmed 4 collaborations

Elly Brockbank 4 collaborations

Asma Faruqi 4 collaborations

A Lindsay Frazier 3 collaborations

Michail Sideris 3 collaborations

Lucy Side 3 collaborations

D Gareth Evans 3 collaborations

Monika Sobocan 3 collaborations

Dhivya Chandrasekaran 3 collaborations

Rowan E Miller 3 collaborations

Tina Mills-Baldock 3 collaborations

Shanthini M Crusz 3 collaborations

Li Sun 3 collaborations

Lucy A Jenkins 3 collaborations

Ajith Kumar 3 collaborations

Laura Casey 3 collaborations

Saurabh Phadnis 3 collaborations

Rosa Legood 3 collaborations

Jonathan Shamash 3 collaborations

H Hockings 2 collaborations

I A McNeish 2 collaborations

E Maniati 2 collaborations

Helen Hockings 2 collaborations

Eszter Lakatos 2 collaborations

Weini Huang 2 collaborations

Maximilian Mossner 2 collaborations

Stephen Metcalf 2 collaborations

Francesco Nicolini 2 collaborations

Trevor A Graham 2 collaborations

Jenny N Poynter 2 collaborations

Samuel Oxley 2 collaborations

Belinda Rahman 2 collaborations

Anne Lanceley 2 collaborations

Jonathan A Ledermann 2 collaborations

Mary McCormack 2 collaborations

Tim Mould 2 collaborations

Steffen Böhm 2 collaborations

Rosalind M Glasspool 2 collaborations

None None 2 collaborations

Arjun Jeyarajah 2 collaborations

Rekha Wuntakal 2 collaborations

Oleg Blyuss 2 collaborations

Ashwin Kalra 2 collaborations

Olivia Evans 2 collaborations

Mary Quigley 2 collaborations

Giorgia Trevisan 2 collaborations

Robert D Morgan 2 collaborations

Daniel M Berney 2 collaborations

Andrew Wallace 2 collaborations

C Newton 1 collaboration

K Murali 1 collaboration

A Ahmad 1 collaboration

R Graham 1 collaboration

V Liberale 1 collaboration

S-J Sarker 1 collaboration

J Ledermann 1 collaboration

D M Berney 1 collaboration

J Shamash 1 collaboration

S Banerjee 1 collaboration

S Stoneham 1 collaboration

J I Hoare 1 collaboration

J Saxena 1 collaboration

V L Silva 1 collaboration

M J Haughey 1 collaboration

G E Wood 1 collaboration

F Nicolini 1 collaboration

H Mirza 1 collaboration

W Huang 1 collaboration

T A Graham 1 collaboration

E H Puttock 1 collaboration

E J Tyler 1 collaboration

M Manni 1 collaboration

C Butterworth 1 collaboration

M Burger Ramos 1 collaboration

E Peerani 1 collaboration

P Hirani 1 collaboration

V Gauthier 1 collaboration

Y Liu 1 collaboration

G Maniscalco 1 collaboration

V Rajeeve 1 collaboration

P Cutillas 1 collaboration

C Trevisan 1 collaboration

M Pozzobon 1 collaboration

J Rastrick 1 collaboration

H Läubli 1 collaboration

A White 1 collaboration

O M T Pearce 1 collaboration

Mohammed Ateeb Khan 1 collaboration

Kane Smith 1 collaboration

Ann-Marie Baker 1 collaboration

Lois B Travis 1 collaboration

Darren R Feldman 1 collaboration

Chunkit Fung 1 collaboration

Shannon M Sullivan 1 collaboration

Deborah F Billmire 1 collaboration

Sarah Ahmed 1 collaboration

Kathryn Baxter 1 collaboration

Dominic Blake 1 collaboration

Victoria Braden 1 collaboration

Mark R Brincat 1 collaboration

Stacey Bryan 1 collaboration

James Dilley 1 collaboration

Stephen Dobbs 1 collaboration

Andrew Durden 1 collaboration

Nana Gomes 1 collaboration

Ben Johnston 1 collaboration

Sonali Kaushik 1 collaboration

Fani Kokka 1 collaboration

Jack Lowe-Zinola 1 collaboration

Aiste McCormick 1 collaboration

Charlotte Nott 1 collaboration

Gemma Louise Owens 1 collaboration

Aayushi Pandya 1 collaboration

Jessica Prince 1 collaboration

Neil Ryan 1 collaboration

Nicole Ryan 1 collaboration

Sameera Tanna 1 collaboration

Justin Waters 1 collaboration

Nathan Zamesa 1 collaboration

Mari Thomas 1 collaboration

Adeola Olaitan 1 collaboration

Rebecca S Kristeleit 1 collaboration

Sara J Stoneham 1 collaboration

Thomas A Olson 1 collaboration

Paul A Cohen 1 collaboration

Aime Powell 1 collaboration

C Blake Gilks 1 collaboration

Colin J R Stewart 1 collaboration

Tarek M Meniawy 1 collaboration

Max Bulsara 1 collaboration

Stefanie Avril 1 collaboration

Eleanor C Brockbank 1 collaboration

Tjalling Bosse 1 collaboration

Gustavo Rubino de Azevedo Focchi 1 collaboration

Raji Ganesan 1 collaboration

Brooke E Howitt 1 collaboration

Hyun-Soo Kim 1 collaboration

Jung-Yun Lee 1 collaboration

Nhu D Le 1 collaboration

Trupti Mandalia 1 collaboration

W Glenn McCluggage 1 collaboration

Iain McNeish 1 collaboration

Divya Midha 1 collaboration

Radhika Srinivasan 1 collaboration

Yun Yi Tan 1 collaboration

Rachael van der Griend 1 collaboration

Mayu Yunokawa 1 collaboration

Gian F Zannoni 1 collaboration

Vera L Silva 1 collaboration

Jayeta Saxena 1 collaboration

Joseph I Hoare 1 collaboration

Sarah A Martin 1 collaboration

Sue Philpott 1 collaboration

Maria Raikou 1 collaboration

Malcolm Scott 1 collaboration

Julian Adlard 1 collaboration

Richard Edmondson 1 collaboration

Emma Roisin Woodward 1 collaboration

Athena Lamnisos 1 collaboration

Janos Balega 1 collaboration

Angela F Brady 1 collaboration

Aarti Sharma 1 collaboration

Louise Izatt 1 collaboration

Anjana Kulkarni 1 collaboration

Vishakha Tripathi 1 collaboration

Joyce S Solomons 1 collaboration

Kevin Hayes 1 collaboration

Helen Hanson 1 collaboration

Katie Snape 1 collaboration

Steve Skates 1 collaboration

Alistair McGuire 1 collaboration

Adam N Rosenthal 1 collaboration

T Goranova 1 collaboration

D Ennis 1 collaboration

A M Piskorz 1 collaboration

G Macintyre 1 collaboration

L A Lewsley 1 collaboration

J Stobo 1 collaboration

C Wilson 1 collaboration

D Kay 1 collaboration

R M Glasspool 1 collaboration

E Brockbank 1 collaboration

A Montes 1 collaboration

A Walther 1 collaboration

S Sundar 1 collaboration

R Edmondson 1 collaboration

G D Hall 1 collaboration

A Clamp 1 collaboration

C Gourley 1 collaboration

M Hall 1 collaboration

C Fotopoulou 1 collaboration

H Gabra 1 collaboration

S Freeman 1 collaboration

L Moore 1 collaboration

M Jimenez-Linan 1 collaboration

J Paul 1 collaboration

J D Brenton 1 collaboration

Nhu Le 1 collaboration

Ian Said 1 collaboration

Blake Gilks 1 collaboration

Adriana Fonseca 1 collaboration

João Lobo 1 collaboration

Florette K Hazard 1 collaboration

Joanna Gell 1 collaboration

Peter K Nicholls 1 collaboration

Robert S Weiss 1 collaboration

Lindsay Klosterkemper 1 collaboration

Samuel L Volchenboum 1 collaboration

James C Nicholson 1 collaboration

James F Amatruda 1 collaboration

Aditya Bagrodia 1 collaboration

Matthew J Murray 1 collaboration

Caitlin Fierheller 1 collaboration

Jacqueline Sia 1 collaboration

Sadiyah Robbani 1 collaboration

Simone Schaefer 1 collaboration

Mark Sladen 1 collaboration

Jaya Nichani 1 collaboration

Kerri Millward 1 collaboration

Morag Lockley 1 collaboration

Martin O'Driscoll 1 collaboration

Karolina Kluk 1 collaboration

Iain A Bruce 1 collaboration

Constantine Alifrangis 1 collaboration

Anand Sharma 1 collaboration

Shafi Chowdhury 1 collaboration

Sarah Duncan 1 collaboration

Marina Milic 1 collaboration

Andrew Gogbashian 1 collaboration

Samita Agarwal 1 collaboration

Anju Sahdev 1 collaboration

Peter Wilson 1 collaboration

Stephen Harland 1 collaboration

Gordon Rustin 1 collaboration

Timothy Oliver 1 collaboration

Daniel Berney 1 collaboration

Iain A McNeish 1 collaboration

Adrian D Cook 1 collaboration

Elizabeth C James 1 collaboration

Rosemary Lord 1 collaboration

Graham Dark 1 collaboration

Jonathan Krell 1 collaboration

Christine Parkinson 1 collaboration

Christopher J Poole 1 collaboration

Marcia Hall 1 collaboration

Dolores Gallardo-Rincón 1 collaboration

Sharadah Essapen 1 collaboration

Jeff Summers 1 collaboration

Anjana Anand 1 collaboration

Abel Zachariah 1 collaboration

Sarah Williams 1 collaboration

Rachel Jones 1 collaboration

Kate Scatchard 1 collaboration

Axel Walther 1 collaboration

Jae-Weon Kim 1 collaboration

Sudha Sundar 1 collaboration

Gordon C Jayson 1 collaboration

Andrew R Clamp 1 collaboration

Rupali Arora 1 collaboration

Laura McLeavy 1 collaboration

Rebecca Kristeleit 1 collaboration

Jonathan Ledermann 1 collaboration

Rory F L Hammond 1 collaboration

Faiza Gaba 1 collaboration

Alexandra C Lawrence 1 collaboration

Fatima El Khouly 1 collaboration

George J Burghel 1 collaboration

Helene Schlecht 1 collaboration

Michael Bulman 1 collaboration

Philip Smith 1 collaboration

Naomi L Bowers 1 collaboration

Radha Graham 1 collaboration

Nicola D MacDonald 1 collaboration

Rowan Miller 1 collaboration

John Butler 1 collaboration

Krithika Murali 1 collaboration

Shah-Jalal Sarker 1 collaboration

Susana Banerjee 1 collaboration

Viola Liberale 1 collaboration

Claire Newton 1 collaboration

Isabel V Rodriguez 1 collaboration

Xia Wei 1 collaboration

Caitlin T Fierheller 1 collaboration

Kelly Rust 1 collaboration

Pavlina Spiliopoulou 1 collaboration

Fatima El-Khouly 1 collaboration

Elizabeth M Swisher 1 collaboration

Charlie Gourley 1 collaboration

Barbara M Norquist 1 collaboration