Mike R Bowl

Affiliations

M Bowl, Radcliffe Department of Medicine, Oxford Centre for Diabetes Endocrinology and Metabolism, Oxford, United Kingdom of Great Britain and Northern Ireland.

Publications (19)

Rare disease gene association discovery from burden analysis of the 100,000 Genomes Project data.

medRxiv : the preprint server for health sciences

Avec: Valentina Cipriani , Letizia Vestito , Emma F Magavern , Julius Ob Jacobsen , Gavin Arno , Elijah R Behr , Katherine A Benson , Marta Bertoli , Detlef Bockenhauer , Michael R Bowl , Kate Burley , Li F Chan , Patrick Chinnery , Peter Conlon , Marcos Costa , Alice E Davidson , Sally J Dawson , Elhussein Elhassan , Sarah E Flanagan , Marta Futema , Daniel P Gale , Sonia García-Ruiz , Cecilia Gonzalez Corcia , Helen R Griffin , Sophie Hambleton , Amy R Hicks , Henry Houlden , Richard S Houlston , Sarah A Howles , Robert Kleta , Iris Lekkerkerker , Siying Lin , Petra Liskova , Hannah Mitchison , Heba Morsy , Andrew D Mumford , William G Newman , Ruxandra Neatu , Edel A O'Toole , Albert Cm Ong , Alistair T Pagnamenta , Shamima Rahman , Neil Rajan , Peter N Robinson , Mina Ryten , Omid Sadeghi-Alavijeh , John A Sayer , Claire L Shovlin , Jenny C Taylor , Omri Teltsh , Ian Tomlinson , Arianna Tucci , Clare Turnbull , Albertien M van Eerde , James S Ware , Laura M Watts , Andrew R Webster , Sarah K Westbury , Sean L Zheng , Mark Caulfield , Damian Smedley

Forward genetics identifies a novel sleep mutant with sleep state inertia and REM sleep deficits.

Science advances

Avec: Gareth T Banks , Mathilde C C Guillaumin , Ines Heise , Petrina Lau , Minghui Yin , Nora Bourbia , Carlos Aguilar , Michael R Bowl , Chris Esapa , Laurence A Brown , Sibah Hasan , Erica Tagliatti , Elizabeth Nicholson , Rasneer Sonia Bains , Sara Wells , Vladyslav V Vyazovskiy , Kirill Volynski , Stuart N Peirson , Patrick M Nolan

Age-Related Hearing Loss.

Cold Spring Harbor perspectives in medicine

Avec: Michael R Bowl , Sally J Dawson

The epilepsy-associated protein TBC1D24 is required for normal development, survival and vesicle trafficking in mammalian neurons.

Human molecular genetics

Avec: Mattéa J Finelli , Davide Aprile , Enrico Castroflorio , Alexander Jeans , Matteo Moschetta , Lauren Chessum , Matteo T Degiacomi , Julia Grasegger , Alexis Lupien-Meilleur , Andrew Bassett , Elsa Rossignol , Philippe M Campeau , Michael R Bowl , Fabio Benfenati , Anna Fassio , Peter L Oliver

Loss of Baiap2l2 destabilizes the transducing stereocilia of cochlear hair cells and leads to deafness.

The Journal of physiology

Avec: Adam J Carlton , Julia Halford , Anna Underhill , Jing-Yi Jeng , Matthew R Avenarius , Merle L Gilbert , Federico Ceriani , Kimimuepigha Ebisine , Steve D M Brown , Michael R Bowl , Peter G Barr-Gillespie , Walter Marcotti

Pathophysiological changes in inner hair cell ribbon synapses in the ageing mammalian cochlea.

The Journal of physiology

Avec: Jing-Yi Jeng , Federico Ceriani , Jennifer Olt , Steve D M Brown , Matthew C Holley , Michael R Bowl , Stuart L Johnson , Walter Marcotti

Studies of mice deleted for Sox3 and uc482: relevance to X-linked hypoparathyroidism.

Endocrine connections

Avec: Katie U Gaynor , Irina V Grigorieva , Samantha M Mirczuk , Sian Piret , Kreepa G Kooblall , Mark Stevenson , Karine Rizzoti , Mike R Bowl , M Andrew Nesbit , Paul T Christie , William D Fraser , Tertius Hough , Michael P Whyte , Robin Lovell-Badge , Rajesh Thakker

Biophysical and morphological changes in inner hair cells and their efferent innervation in the ageing mouse cochlea.

The Journal of physiology

Avec: Jing-Yi Jeng , Adam J Carlton , Stuart L Johnson , Steve D M Brown , Matthew C Holley , Michael R Bowl , Walter Marcotti

Structural basis for tunable control of actin dynamics by myosin-15 in mechanosensory stereocilia.

Science advances

Avec: Rui Gong , Fangfang Jiang , Zane G Moreland , Matthew J Reynolds , Santiago Espinosa de Los Reyes , Pinar Gurel , Arik Shams , James B Heidings , Michael R Bowl , Jonathan E Bird , Gregory M Alushin

A biallelic variant in CLRN2 causes non-syndromic hearing loss in humans.

Human genetics

Avec: Barbara Vona , Neda Mazaheri , Sheng-Jia Lin , Lucy A Dunbar , Reza Maroofian , Hela Azaiez , Kevin T Booth , Sandrine Vitry , Aboulfazl Rad , Franz Rüschendorf , Pratishtha Varshney , Ben Fowler , Christian Beetz , Kumar N Alagramam , David Murphy , Gholamreza Shariati , Alireza Sedaghat , Henry Houlden , Cassidy Petree , Shruthi VijayKumar , Richard J H Smith , Thomas Haaf , Aziz El-Amraoui , Michael R Bowl , Gaurav K Varshney , Hamid Galehdari

Neuroplastin genetically interacts with Cadherin 23 and the encoded isoform Np55 is sufficient for cochlear hair cell function and hearing.

PLoS genetics

Avec: Sherylanne Newton , Fanbo Kong , Adam J Carlton , Carlos Aguilar , Andrew Parker , Gemma F Codner , Lydia Teboul , Sara Wells , Steve D M Brown , Walter Marcotti , Michael R Bowl

Absence of Embigin accelerates hearing loss and causes sub-viability, brain and heart defects in C57BL/6N mice due to interaction with

iScience

Avec: Sherylanne Newton , Carlos Aguilar , Rosie K Bunton-Stasyshyn , Marisa Flook , Michelle Stewart , Walter Marcotti , Steve Brown , Michael R Bowl

BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing.

Cell reports

Avec: Adam J Carlton , Jing-Yi Jeng , Fiorella C Grandi , Francesca De Faveri , Ana E Amariutei , Lara De Tomasi , Andrew O'Connor , Stuart L Johnson , David N Furness , Steve D M Brown , Federico Ceriani , Michael R Bowl , Mirna Mustapha , Walter Marcotti

Clarin-2 is essential for hearing by maintaining stereocilia integrity and function.

EMBO molecular medicine

Avec: Lucy A Dunbar , Pranav Patni , Carlos Aguilar , Philomena Mburu , Laura Corns , Helena Rr Wells , Sedigheh Delmaghani , Andrew Parker , Stuart Johnson , Debbie Williams , Christopher T Esapa , Michelle M Simon , Lauren Chessum , Sherylanne Newton , Joanne Dorning , Prashanthini Jeyarajan , Susan Morse , Andrea Lelli , Gemma F Codner , Thibault Peineau , Suhasini R Gopal , Kumar N Alagramam , Ronna Hertzano , Didier Dulon , Sara Wells , Frances M Williams , Christine Petit , Sally J Dawson , Steve Dm Brown , Walter Marcotti , Aziz El-Amraoui , Michael R Bowl

Age-related changes in the biophysical and morphological characteristics of mouse cochlear outer hair cells.

The Journal of physiology

Avec: Jing-Yi Jeng , Stuart L Johnson , Adam J Carlton , Lara De Tomasi , Richard J Goodyear , Francesca De Faveri , David N Furness , Sara Wells , Steve D M Brown , Matthew C Holley , Guy P Richardson , Mirna Mustapha , Michael R Bowl , Walter Marcotti

Clarin-2 gene supplementation durably preserves hearing in a model of progressive hearing loss.

Molecular therapy : the journal of the American Society of Gene Therapy

Avec: Clara Mendia , Thibault Peineau , Mina Zamani , Chloé Felgerolle , Nawal Yahiaoui , Nele Christophersen , Samantha Papal , Audrey Maudoux , Reza Maroofian , Pranav Patni , Sylvie Nouaille , Michael R Bowl , Sedigheh Delmaghani , Hamid Galehdari , Barbara Vona , Didier Dulon , Sandrine Vitry , Aziz El-Amraoui

AAV-mediated rescue of

Molecular therapy. Methods & clinical development

Avec: Jing-Yi Jeng , Adam J Carlton , Richard J Goodyear , Colbie Chinowsky , Federico Ceriani , Stuart L Johnson , Tsung-Chang Sung , Yelena Dayn , Guy P Richardson , Michael R Bowl , Steve D M Brown , Uri Manor , Walter Marcotti

Expanding the spectrum of phenotypes for MPDZ: Report of four unrelated families and review of the literature.

Clinical genetics

Avec: Aboulfazl Rad , Oliver Bartsch , Somayeh Bakhtiari , Changlian Zhu , Yiran Xu , Fabíola P Monteiro , Fernando Kok , Anneke T Vulto-van Silfhout , Michael C Kruer , Michael R Bowl , Barbara Vona

CIB2 function is distinct from Whirlin in the development of cochlear stereocilia staircase pattern.

bioRxiv : the preprint server for biology

Avec: Arnaud P J Giese , Andrew Parker , Sakina Rehman , Steve D M Brown , Saima Riazuddin , Craig W Vander Kooi , Michael R Bowl , Zubair M Ahmed

Réseau de co-auteurs

Michael R Bowl 18 collaborations

Walter Marcotti 9 collaborations

Steve D M Brown 8 collaborations

Adam J Carlton 6 collaborations

Jing-Yi Jeng 6 collaborations

Stuart L Johnson 5 collaborations

Carlos Aguilar 4 collaborations

Sara Wells 4 collaborations

Federico Ceriani 4 collaborations

Sally J Dawson 3 collaborations

Matthew C Holley 3 collaborations

Barbara Vona 3 collaborations

Aziz El-Amraoui 3 collaborations

Sherylanne Newton 3 collaborations

Andrew Parker 3 collaborations

Henry Houlden 2 collaborations

Lauren Chessum 2 collaborations

Lucy A Dunbar 2 collaborations

Reza Maroofian 2 collaborations

Sandrine Vitry 2 collaborations

Aboulfazl Rad 2 collaborations

Kumar N Alagramam 2 collaborations

Hamid Galehdari 2 collaborations

Gemma F Codner 2 collaborations

Francesca De Faveri 2 collaborations

Lara De Tomasi 2 collaborations

David N Furness 2 collaborations

Mirna Mustapha 2 collaborations

Pranav Patni 2 collaborations

Sedigheh Delmaghani 2 collaborations

Thibault Peineau 2 collaborations

Didier Dulon 2 collaborations

Richard J Goodyear 2 collaborations

Guy P Richardson 2 collaborations

Valentina Cipriani 1 collaboration

Letizia Vestito 1 collaboration

Emma F Magavern 1 collaboration

Julius Ob Jacobsen 1 collaboration

Gavin Arno 1 collaboration

Elijah R Behr 1 collaboration

Katherine A Benson 1 collaboration

Marta Bertoli 1 collaboration

Detlef Bockenhauer 1 collaboration

Kate Burley 1 collaboration

Li F Chan 1 collaboration

Patrick Chinnery 1 collaboration

Peter Conlon 1 collaboration

Marcos Costa 1 collaboration

Alice E Davidson 1 collaboration

Elhussein Elhassan 1 collaboration

Sarah E Flanagan 1 collaboration

Marta Futema 1 collaboration

Daniel P Gale 1 collaboration

Sonia García-Ruiz 1 collaboration

Cecilia Gonzalez Corcia 1 collaboration

Helen R Griffin 1 collaboration

Sophie Hambleton 1 collaboration

Amy R Hicks 1 collaboration

Richard S Houlston 1 collaboration

Sarah A Howles 1 collaboration

Robert Kleta 1 collaboration

Iris Lekkerkerker 1 collaboration

Siying Lin 1 collaboration

Petra Liskova 1 collaboration

Hannah Mitchison 1 collaboration

Heba Morsy 1 collaboration

Andrew D Mumford 1 collaboration

William G Newman 1 collaboration

Ruxandra Neatu 1 collaboration

Edel A O'Toole 1 collaboration

Albert Cm Ong 1 collaboration

Alistair T Pagnamenta 1 collaboration

Shamima Rahman 1 collaboration

Neil Rajan 1 collaboration

Peter N Robinson 1 collaboration

Mina Ryten 1 collaboration

Omid Sadeghi-Alavijeh 1 collaboration

John A Sayer 1 collaboration

Claire L Shovlin 1 collaboration

Jenny C Taylor 1 collaboration

Omri Teltsh 1 collaboration

Ian Tomlinson 1 collaboration

Arianna Tucci 1 collaboration

Clare Turnbull 1 collaboration

Albertien M van Eerde 1 collaboration

James S Ware 1 collaboration

Laura M Watts 1 collaboration

Andrew R Webster 1 collaboration

Sarah K Westbury 1 collaboration

Sean L Zheng 1 collaboration

Mark Caulfield 1 collaboration

Damian Smedley 1 collaboration

Gareth T Banks 1 collaboration

Mathilde C C Guillaumin 1 collaboration

Ines Heise 1 collaboration

Petrina Lau 1 collaboration

Minghui Yin 1 collaboration

Nora Bourbia 1 collaboration

Chris Esapa 1 collaboration

Laurence A Brown 1 collaboration

Sibah Hasan 1 collaboration

Erica Tagliatti 1 collaboration

Elizabeth Nicholson 1 collaboration

Rasneer Sonia Bains 1 collaboration

Vladyslav V Vyazovskiy 1 collaboration

Kirill Volynski 1 collaboration

Stuart N Peirson 1 collaboration

Patrick M Nolan 1 collaboration

Mattéa J Finelli 1 collaboration

Davide Aprile 1 collaboration

Enrico Castroflorio 1 collaboration

Alexander Jeans 1 collaboration

Matteo Moschetta 1 collaboration

Matteo T Degiacomi 1 collaboration

Julia Grasegger 1 collaboration

Alexis Lupien-Meilleur 1 collaboration

Andrew Bassett 1 collaboration

Elsa Rossignol 1 collaboration

Philippe M Campeau 1 collaboration

Fabio Benfenati 1 collaboration

Anna Fassio 1 collaboration

Peter L Oliver 1 collaboration

Julia Halford 1 collaboration

Anna Underhill 1 collaboration

Matthew R Avenarius 1 collaboration

Merle L Gilbert 1 collaboration

Kimimuepigha Ebisine 1 collaboration

Peter G Barr-Gillespie 1 collaboration

Jennifer Olt 1 collaboration

Katie U Gaynor 1 collaboration

Irina V Grigorieva 1 collaboration

Samantha M Mirczuk 1 collaboration

Sian Piret 1 collaboration

Kreepa G Kooblall 1 collaboration

Mark Stevenson 1 collaboration

Karine Rizzoti 1 collaboration

M Andrew Nesbit 1 collaboration

Paul T Christie 1 collaboration

William D Fraser 1 collaboration

Tertius Hough 1 collaboration

Michael P Whyte 1 collaboration

Robin Lovell-Badge 1 collaboration

Rajesh Thakker 1 collaboration

Rui Gong 1 collaboration

Fangfang Jiang 1 collaboration

Zane G Moreland 1 collaboration

Matthew J Reynolds 1 collaboration

Santiago Espinosa de Los Reyes 1 collaboration

Pinar Gurel 1 collaboration

Arik Shams 1 collaboration

James B Heidings 1 collaboration

Jonathan E Bird 1 collaboration

Gregory M Alushin 1 collaboration

Neda Mazaheri 1 collaboration

Sheng-Jia Lin 1 collaboration

Hela Azaiez 1 collaboration

Kevin T Booth 1 collaboration

Franz Rüschendorf 1 collaboration

Pratishtha Varshney 1 collaboration

Ben Fowler 1 collaboration

Christian Beetz 1 collaboration

David Murphy 1 collaboration

Gholamreza Shariati 1 collaboration

Alireza Sedaghat 1 collaboration

Cassidy Petree 1 collaboration

Shruthi VijayKumar 1 collaboration

Richard J H Smith 1 collaboration

Thomas Haaf 1 collaboration

Gaurav K Varshney 1 collaboration

Fanbo Kong 1 collaboration

Lydia Teboul 1 collaboration

Rosie K Bunton-Stasyshyn 1 collaboration

Marisa Flook 1 collaboration

Michelle Stewart 1 collaboration

Steve Brown 1 collaboration

Fiorella C Grandi 1 collaboration

Ana E Amariutei 1 collaboration

Andrew O'Connor 1 collaboration

Philomena Mburu 1 collaboration

Laura Corns 1 collaboration

Helena Rr Wells 1 collaboration

Stuart Johnson 1 collaboration

Debbie Williams 1 collaboration

Christopher T Esapa 1 collaboration

Michelle M Simon 1 collaboration

Joanne Dorning 1 collaboration

Prashanthini Jeyarajan 1 collaboration

Susan Morse 1 collaboration

Andrea Lelli 1 collaboration

Suhasini R Gopal 1 collaboration

Ronna Hertzano 1 collaboration

Frances M Williams 1 collaboration

Christine Petit 1 collaboration

Steve Dm Brown 1 collaboration

Clara Mendia 1 collaboration

Mina Zamani 1 collaboration

Chloé Felgerolle 1 collaboration

Nawal Yahiaoui 1 collaboration

Nele Christophersen 1 collaboration

Samantha Papal 1 collaboration

Audrey Maudoux 1 collaboration

Sylvie Nouaille 1 collaboration

Colbie Chinowsky 1 collaboration

Tsung-Chang Sung 1 collaboration

Yelena Dayn 1 collaboration

Uri Manor 1 collaboration

Oliver Bartsch 1 collaboration

Somayeh Bakhtiari 1 collaboration

Changlian Zhu 1 collaboration

Yiran Xu 1 collaboration

Fabíola P Monteiro 1 collaboration

Fernando Kok 1 collaboration

Anneke T Vulto-van Silfhout 1 collaboration

Michael C Kruer 1 collaboration

Arnaud P J Giese 1 collaboration

Sakina Rehman 1 collaboration

Saima Riazuddin 1 collaboration

Craig W Vander Kooi 1 collaboration

Zubair M Ahmed 1 collaboration