Murat Saparbaev

Affiliations

Department of Molecular Biology and Genetics, Faculty of Biology and Biotechnology, al-Farabi Kazakh National University, Almaty, Kazakhstan.
Groupe ≪Mechanisms of DNA Repair and Carcinogenesis≫, Equipe Labellisée LIGUE 2016, CNRS UMR9019, Université Paris-Saclay, Gustave Roussy Cancer Campus, Villejuif, France.

Publications (23)

Role of Base Excision Repair Pathway in the Processing of Complex DNA Damage Generated by Oxidative Stress and Anticancer Drugs.

Frontiers in cell and developmental biology

Avec: Yeldar Baiken , Damira Kanayeva , Sabira Taipakova , Regina Groisman , Alexander A Ishchenko , Dinara Begimbetova , Bakhyt Matkarimov , Murat Saparbaev

Comparative Analysis of Exo- and Endonuclease Activities of APE1-like Enzymes.

International journal of molecular sciences

Avec: Anastasiia T Davletgildeeva , Alexandra A Kuznetsova , Darya S Novopashina , Alexander A Ishchenko , Murat Saparbaev , Olga S Fedorova , Nikita A Kuznetsov

Conformational Dynamics of Human ALKBH2 Dioxygenase in the Course of DNA Repair as Revealed by Stopped-Flow Fluorescence Spectroscopy.

Molecules (Basel, Switzerland)

Avec: Lyubov Yu Kanazhevskaya , Denis A Smyshliaev , Nadezhda A Timofeyeva , Alexander A Ishchenko , Murat Saparbaev , Nikita A Kuznetsov , Olga S Fedorova

Pre-steady-state kinetic and mutational insights into mechanisms of endo- and exonuclease DNA processing by mutant forms of human AP endonuclease.

Biochimica et biophysica acta. General subjects

Avec: Artemiy S Bakman , Alexander A Ishchenko , Murat Saparbaev , Olga S Fedorova , Nikita A Kuznetsov

Wheat Germination Is Dependent on Plant Target of Rapamycin Signaling.

Frontiers in cell and developmental biology

Avec: Bauyrzhan Smailov , Sanzhar Alybayev , Izat Smekenov , Aibek Mursalimov , Murat Saparbaev , Dos Sarbassov , Amangeldy Bissenbaev

Fluorescently labeled human apurinic/apyrimidinic endonuclease APE1 reveals effects of DNA polymerase β on the APE1-DNA interaction.

DNA repair

Avec: Artemiy S Bakman , Aleksandra A Kuznetsova , Lyudmila V Yanshole , Alexander A Ishchenko , Murat Saparbaev , Olga S Fedorova , Nikita A Kuznetsov

NEIL3-mediated proteasomal degradation facilitates the repair of cisplatin-induced DNA damage in human cells.

Scientific reports

Avec: Umit Aliyaskarova , Yeldar Baiken , Flore Renaud , Sophie Couve , Alexei F Kisselev , Murat Saparbaev , Regina Groisman

An Insight into the Mechanism of DNA Cleavage by DNA Endonuclease from the Hyperthermophilic Archaeon

International journal of molecular sciences

Avec: Anastasiia T Davletgildeeva , Aleksandra A Kuznetsova , Alexander A Ishchenko , Murat Saparbaev , Nikita A Kuznetsov

Mechanism of stimulation of DNA binding of the transcription factors by human apurinic/apyrimidinic endonuclease 1, APE1.

DNA repair

Avec: Milena Bazlekowa-Karaban , Paulina Prorok , Sonia Baconnais , Sabira Taipakova , Zhiger Akishev , Dominika Zembrzuska , Alexander V Popov , Anton V Endutkin , Regina Groisman , Alexander A Ishchenko , Bakhyt T Matkarimov , Amangeldy Bissenbaev , Eric Le Cam , Dmitry O Zharkov , Barbara Tudek , Murat Saparbaev

DNA-Histone Cross-Links: Formation and Repair.

Frontiers in cell and developmental biology

Avec: Manideep C Pachva , Alexei F Kisselev , Bakhyt T Matkarimov , Murat Saparbaev , Regina Groisman

The

Frontiers in cell and developmental biology

Avec: Sabira Taipakova , Aigerim Kuanbay , Christine Saint-Pierre , Didier Gasparutto , Yeldar Baiken , Regina Groisman , Alexander A Ishchenko , Murat Saparbaev , Amangeldy K Bissenbaev

The Impact of Human DNA Glycosylases on the Activity of DNA Polymerase β toward Various Base Excision Repair Intermediates.

International journal of molecular sciences

Avec: Artemiy S Bakman , Stanislav S Boichenko , Aleksandra A Kuznetsova , Alexander A Ishchenko , Murat Saparbaev , Nikita A Kuznetsov

Coordination between human DNA polymerase β and apurinic/apyrimidinic endonuclease 1 in the course of DNA repair.

Biochimie

Avec: Artemiy S Bakman , Stanislav S Boichenko , Aleksandra A Kuznetsova , Alexander A Ishchenko , Murat Saparbaev , Nikita A Kuznetsov

DCLRE1B/Apollo germline mutations associated with renal cell carcinoma impair telomere protection.

Biochimica et biophysica acta. Molecular basis of disease

Avec: Charlie Bories , Thomas Lejour , Florine Adolphe , Laëtitia Kermasson , Sophie Couvé , Laura Tanguy , Gabriela Luszczewska , Manon Watzky , Victoria Poillerat , Pauline Garnier , Regina Groisman , Sophie Ferlicot , Stéphane Richard , Murat Saparbaev , Patrick Revy , Sophie Gad , Flore Renaud

Reading Targeted DNA Damage in the Active Demethylation Pathway: Role of Accessory Domains of Eukaryotic AP Endonucleases and Thymine-DNA Glycosylases.

Journal of molecular biology

Avec: Alexander V Popov , Inga R Grin , Antonina P Dvornikova , Bakhyt T Matkarimov , Regina Groisman , Murat Saparbaev , Dmitry O Zharkov

The Enigma of Substrate Recognition and Catalytic Efficiency of APE1-Like Enzymes.

Frontiers in cell and developmental biology

Avec: Anastasiia T Davletgildeeva , Alexander A Ishchenko , Murat Saparbaev , Olga S Fedorova , Nikita A Kuznetsov

Common Kinetic Mechanism of Abasic Site Recognition by Structurally Different Apurinic/Apyrimidinic Endonucleases.

International journal of molecular sciences

Avec: Alexandra A Kuznetsova , Svetlana I Senchurova , Alexander A Ishchenko , Murat Saparbaev , Olga S Fedorova , Nikita A Kuznetsov

The mechanism of damage recognition by apurinic/apyrimidinic endonuclease Nfo from Escherichia coli.

Biochimica et biophysica acta. General subjects

Avec: Svetlana I Senchurova , Victoria N Syryamina , Aleksandra A Kuznetsova , Darya S Novopashina , Alexander A Ishchenko , Murat Saparbaev , Sergei A Dzuba , Olga S Fedorova , Nikita A Kuznetsov

Cloning and characterization of the major AP endonuclease from Staphylococcus aureus.

DNA repair

Avec: Aigerim Turgimbayeva , Ulan Zein , Dmitry O Zharkov , Yerlan Ramankulov , Murat Saparbaev , Sailau Abeldenov

Kinetic Features of 3'-5'-Exonuclease Activity of Apurinic/Apyrimidinic Endonuclease Apn2 from

International journal of molecular sciences

Avec: Aleksandra A Kuznetsova , Anastasia A Gavrilova , Alexander A Ishchenko , Murat Saparbaev , Olga S Fedorova , Nikita A Kuznetsov

Modulation of the Apurinic/Apyrimidinic Endonuclease Activity of Human APE1 and of Its Natural Polymorphic Variants by Base Excision Repair Proteins.

International journal of molecular sciences

Avec: Olga A Kladova , Irina V Alekseeva , Murat Saparbaev , Olga S Fedorova , Nikita A Kuznetsov

Evolutionary Origins of DNA Repair Pathways: Role of Oxygen Catastrophe in the Emergence of DNA Glycosylases.

Cells

Avec: Paulina Prorok , Inga R Grin , Bakhyt T Matkarimov , Alexander A Ishchenko , Jacques Laval , Dmitry O Zharkov , Murat Saparbaev

Individual Contributions of Amido Acid Residues Tyr122, Ile168, and Asp173 to the Activity and Substrate Specificity of Human DNA Dioxygenase ABH2.

Cells

Avec: Anastasiia T Davletgildeeva , Timofey E Tyugashev , Mingxing Zhao , Nikita A Kuznetsov , Alexander A Ishchenko , Murat Saparbaev , Aleksandra A Kuznetsova

Réseau de co-auteurs

Alexander A Ishchenko 16 collaborations

Nikita A Kuznetsov 13 collaborations

Olga S Fedorova 9 collaborations

Regina Groisman 7 collaborations

Aleksandra A Kuznetsova 7 collaborations

Anastasiia T Davletgildeeva 4 collaborations

Artemiy S Bakman 4 collaborations

Bakhyt T Matkarimov 4 collaborations

Dmitry O Zharkov 4 collaborations

Yeldar Baiken 3 collaborations

Sabira Taipakova 3 collaborations

Alexandra A Kuznetsova 2 collaborations

Darya S Novopashina 2 collaborations

Amangeldy Bissenbaev 2 collaborations

Flore Renaud 2 collaborations

Alexei F Kisselev 2 collaborations

Paulina Prorok 2 collaborations

Alexander V Popov 2 collaborations

Stanislav S Boichenko 2 collaborations

Inga R Grin 2 collaborations

Svetlana I Senchurova 2 collaborations

Damira Kanayeva 1 collaboration

Dinara Begimbetova 1 collaboration

Bakhyt Matkarimov 1 collaboration

Lyubov Yu Kanazhevskaya 1 collaboration

Denis A Smyshliaev 1 collaboration

Nadezhda A Timofeyeva 1 collaboration

Bauyrzhan Smailov 1 collaboration

Sanzhar Alybayev 1 collaboration

Izat Smekenov 1 collaboration

Aibek Mursalimov 1 collaboration

Dos Sarbassov 1 collaboration

Lyudmila V Yanshole 1 collaboration

Umit Aliyaskarova 1 collaboration

Sophie Couve 1 collaboration

Milena Bazlekowa-Karaban 1 collaboration

Sonia Baconnais 1 collaboration

Zhiger Akishev 1 collaboration

Dominika Zembrzuska 1 collaboration

Anton V Endutkin 1 collaboration

Eric Le Cam 1 collaboration

Barbara Tudek 1 collaboration

Manideep C Pachva 1 collaboration

Aigerim Kuanbay 1 collaboration

Christine Saint-Pierre 1 collaboration

Didier Gasparutto 1 collaboration

Amangeldy K Bissenbaev 1 collaboration

Charlie Bories 1 collaboration

Thomas Lejour 1 collaboration

Florine Adolphe 1 collaboration

Laëtitia Kermasson 1 collaboration

Sophie Couvé 1 collaboration

Laura Tanguy 1 collaboration

Gabriela Luszczewska 1 collaboration

Manon Watzky 1 collaboration

Victoria Poillerat 1 collaboration

Pauline Garnier 1 collaboration

Sophie Ferlicot 1 collaboration

Stéphane Richard 1 collaboration

Patrick Revy 1 collaboration

Sophie Gad 1 collaboration

Antonina P Dvornikova 1 collaboration

Victoria N Syryamina 1 collaboration

Sergei A Dzuba 1 collaboration

Aigerim Turgimbayeva 1 collaboration

Ulan Zein 1 collaboration

Yerlan Ramankulov 1 collaboration

Sailau Abeldenov 1 collaboration

Anastasia A Gavrilova 1 collaboration

Olga A Kladova 1 collaboration

Irina V Alekseeva 1 collaboration

Jacques Laval 1 collaboration

Timofey E Tyugashev 1 collaboration

Mingxing Zhao 1 collaboration