Nancy Holroyd

Affiliations

Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, CB10 1SA, UK.

Publications (18)

Sex chromosome evolution in parasitic nematodes of humans.

Nature communications

Avec: Jeremy M Foster , Alexandra Grote , John Mattick , Alan Tracey , Yu-Chih Tsai , Matthew Chung , James A Cotton , Tyson A Clark , Adam Geber , Nancy Holroyd , Jonas Korlach , Yichao Li , Silvia Libro , Sara Lustigman , Michelle L Michalski , Michael Paulini , Matthew B Rogers , Laura Teigen , Alan Twaddle , Lonnie Welch , Matthew Berriman , Julie C Dunning Hotopp , Elodie Ghedin

Complete representation of a tapeworm genome reveals chromosomes capped by centromeres, necessitating a dual role in segregation and protection.

BMC biology

Avec: Peter D Olson , Alan Tracey , Andrew Baillie , Katherine James , Stephen R Doyle , Sarah K Buddenborg , Faye H Rodgers , Nancy Holroyd , Matt Berriman

Genomic and transcriptomic variation defines the chromosome-scale assembly of Haemonchus contortus, a model gastrointestinal worm.

Communications biology

Avec: Stephen R Doyle , Alan Tracey , Roz Laing , Nancy Holroyd , David Bartley , Wojtek Bazant , Helen Beasley , Robin Beech , Collette Britton , Karen Brooks , Umer Chaudhry , Kirsty Maitland , Axel Martinelli , Jennifer D Noonan , Michael Paulini , Michael A Quail , Elizabeth Redman , Faye H Rodgers , Guillaume Sallé , Muhammad Zubair Shabbir , Geetha Sankaranarayanan , Janneke Wit , Kevin L Howe , Neil Sargison , Eileen Devaney , Matthew Berriman , John S Gilleard , James A Cotton

Population genomic evidence that human and animal infections in Africa come from the same populations of Dracunculus medinensis.

PLoS neglected tropical diseases

Avec: Caroline Durrant , Elizabeth A Thiele , Nancy Holroyd , Stephen R Doyle , Guillaume Sallé , Alan Tracey , Geetha Sankaranarayanan , Magda E Lotkowska , Hayley M Bennett , Thomas Huckvale , Zahra Abdellah , Ouakou Tchindebet , Mesfin Wossen , Makoy Samuel Yibi Logora , Cheick Oumar Coulibaly , Adam Weiss , Albrecht I Schulte-Hostedde , Jeremy M Foster , Christopher A Cleveland , Michael J Yabsley , Ernesto Ruiz-Tiben , Matthew Berriman , Mark L Eberhard , James A Cotton

Multiscale three-dimensional imaging of intact human organs down to the cellular scale using hierarchical phase-contrast tomography.

bioRxiv : the preprint server for biology

Avec: C Walsh , P Tafforeau , Willi L Wagner , D J Jafree , A Bellier , C Werlein , M P Kühnel , E Boller , S Walker-Samuel , J L Robertus , D A Long , J Jacob , S Marussi , E Brown , N Holroyd , D D Jonigk , M Ackermann , P D Lee

Whole-genome sequencing of Schistosoma mansoni reveals extensive diversity with limited selection despite mass drug administration.

Nature communications

Avec: Duncan J Berger , Thomas Crellen , Poppy H L Lamberton , Fiona Allan , Alan Tracey , Jennifer D Noonan , Narcis B Kabatereine , Edridah M Tukahebwa , Moses Adriko , Nancy Holroyd , Joanne P Webster , Matthew Berriman , James A Cotton

Modular type I polyketide synthase acyl carrier protein domains share a common N-terminally extended fold.

Scientific reports

Avec: Luisa Moretto , Rachel Heylen , Natalie Holroyd , Steven Vance , R William Broadhurst

Deciphering the role of miR-71 in Echinococcus multilocularis early development in vitro.

PLoS neglected tropical diseases

Avec: Matías Gastón Pérez , Markus Spiliotis , Natalia Rego , Natalia Macchiaroli , Laura Kamenetzky , Nancy Holroyd , Marcela Alejandra Cucher , Klaus Brehm , Mara Cecilia Rosenzvit

Nearly Complete Genome Sequence of Brugia malayi Strain FR3.

Microbiology resource announcements

Avec: Alan Tracey , Jeremy M Foster , Michael Paulini , Alexandra Grote , John Mattick , Yu-Chih Tsai , Matthew Chung , James A Cotton , Tyson A Clark , Adam Geber , Nancy Holroyd , Jonas Korlach , Silvia Libro , Sara Lustigman , Michelle L Michalski , Matthew B Rogers , Alan Twaddle , Julie C Dunning Hotopp , Matthew Berriman , Elodie Ghedin

Genome-wide analysis of Schistosoma mansoni reveals limited population structure and possible praziquantel drug selection pressure within Ugandan hot-spot communities.

PLoS neglected tropical diseases

Avec: Tushabe John Vianney , Duncan J Berger , Stephen R Doyle , Geetha Sankaranarayanan , Joel Serubanja , Prossy Kabuubi Nakawungu , Fred Besigye , Richard E Sanya , Nancy Holroyd , Fiona Allan , Emily L Webb , Alison M Elliott , Matthew Berriman , James A Cotton

Genomic landscape of drug response reveals mediators of anthelmintic resistance.

Cell reports

Avec: Stephen R Doyle , Roz Laing , David Bartley , Alison Morrison , Nancy Holroyd , Kirsty Maitland , Alistair Antonopoulos , Umer Chaudhry , Ilona Flis , Sue Howell , Jennifer McIntyre , John S Gilleard , Andy Tait , Barbara Mable , Ray Kaplan , Neil Sargison , Collette Britton , Matthew Berriman , Eileen Devaney , James A Cotton

A drug repurposing screen for whipworms informed by comparative genomics.

PLoS neglected tropical diseases

Avec: Avril Coghlan , Frederick A Partridge , María Adelaida Duque-Correa , Gabriel Rinaldi , Simon Clare , Lisa Seymour , Cordelia Brandt , Tapoka T Mkandawire , Catherine McCarthy , Nancy Holroyd , Marina Nick , Anwen E Brown , Sirapat Tonitiwong , David B Sattelle , Matthew Berriman

Genome-wide transcriptome analysis of

Frontiers in cellular and infection microbiology

Avec: Michaela Herz , Magdalena Zarowiecki , Leonie Wessels , Katharina Pätzel , Ruth Herrmann , Christiane Braun , Nancy Holroyd , Thomas Huckvale , Monika Bergmann , Markus Spiliotis , Uriel Koziol , Matthew Berriman , Klaus Brehm

The global diversity of Haemonchus contortus is shaped by human intervention and climate.

Nature communications

Avec: G Sallé , S R Doyle , J Cortet , J Cabaret , M Berriman , N Holroyd , J A Cotton

Population genomic and evolutionary modelling analyses reveal a single major QTL for ivermectin drug resistance in the pathogenic nematode, Haemonchus contortus.

BMC genomics

Avec: Stephen R Doyle , Christopher J R Illingworth , Roz Laing , David J Bartley , Elizabeth Redman , Axel Martinelli , Nancy Holroyd , Alison A Morrison , Andrew Rezansoff , Alan Tracey , Eileen Devaney , Matthew Berriman , Neil Sargison , James A Cotton , John S Gilleard

Daily rhythms in gene expression of the human parasite Schistosoma mansoni.

BMC biology

Avec: Kate A Rawlinson , Adam J Reid , Zhigang Lu , Patrick Driguez , Anna Wawer , Avril Coghlan , Geetha Sankaranarayanan , Sarah K Buddenborg , Carmen Diaz Soria , Catherine McCarthy , Nancy Holroyd , Mandy Sanders , Karl F Hoffmann , David Wilcockson , Gabriel Rinaldi , Matthew Berriman

Extracellular non-coding RNA signatures of the metacestode stage of Echinococcus multilocularis.

PLoS neglected tropical diseases

Avec: María Eugenia Ancarola , Gabriel Lichtenstein , Johannes Herbig , Nancy Holroyd , Mara Mariconti , Enrico Brunetti , Matthew Berriman , Krystyna Albrecht , Antonio Marcilla , Mara Cecilia Rosenzvit , Laura Kamenetzky , Klaus Brehm , Marcela Cucher

Challenges and opportunities of integrating imaging and mathematical modelling to interrogate biological processes.

The international journal of biochemistry & cell biology

Avec: Maxime Berg , Natalie Holroyd , Claire Walsh , Hannah West , Simon Walker-Samuel , Rebecca Shipley

Réseau de co-auteurs

Matthew Berriman 12 collaborations

James A Cotton 8 collaborations

Alan Tracey 7 collaborations

Stephen R Doyle 6 collaborations

Geetha Sankaranarayanan 4 collaborations

Jeremy M Foster 3 collaborations

Michael Paulini 3 collaborations

Roz Laing 3 collaborations

Neil Sargison 3 collaborations

Eileen Devaney 3 collaborations

John S Gilleard 3 collaborations

Klaus Brehm 3 collaborations

Alexandra Grote 2 collaborations

John Mattick 2 collaborations

Yu-Chih Tsai 2 collaborations

Matthew Chung 2 collaborations

Tyson A Clark 2 collaborations

Adam Geber 2 collaborations

Jonas Korlach 2 collaborations

Silvia Libro 2 collaborations

Sara Lustigman 2 collaborations

Michelle L Michalski 2 collaborations

Matthew B Rogers 2 collaborations

Alan Twaddle 2 collaborations

Julie C Dunning Hotopp 2 collaborations

Elodie Ghedin 2 collaborations

Sarah K Buddenborg 2 collaborations

Faye H Rodgers 2 collaborations

David Bartley 2 collaborations

Collette Britton 2 collaborations

Umer Chaudhry 2 collaborations

Kirsty Maitland 2 collaborations

Axel Martinelli 2 collaborations

Jennifer D Noonan 2 collaborations

Elizabeth Redman 2 collaborations

Guillaume Sallé 2 collaborations

Thomas Huckvale 2 collaborations

N Holroyd 2 collaborations

Duncan J Berger 2 collaborations

Fiona Allan 2 collaborations

Natalie Holroyd 2 collaborations

Markus Spiliotis 2 collaborations

Laura Kamenetzky 2 collaborations

Mara Cecilia Rosenzvit 2 collaborations

Avril Coghlan 2 collaborations

Gabriel Rinaldi 2 collaborations

Catherine McCarthy 2 collaborations

Yichao Li 1 collaboration

Laura Teigen 1 collaboration

Lonnie Welch 1 collaboration

Peter D Olson 1 collaboration

Andrew Baillie 1 collaboration

Katherine James 1 collaboration

Matt Berriman 1 collaboration

Wojtek Bazant 1 collaboration

Helen Beasley 1 collaboration

Robin Beech 1 collaboration

Karen Brooks 1 collaboration

Michael A Quail 1 collaboration

Muhammad Zubair Shabbir 1 collaboration

Janneke Wit 1 collaboration

Kevin L Howe 1 collaboration

Caroline Durrant 1 collaboration

Elizabeth A Thiele 1 collaboration

Magda E Lotkowska 1 collaboration

Hayley M Bennett 1 collaboration

Zahra Abdellah 1 collaboration

Ouakou Tchindebet 1 collaboration

Mesfin Wossen 1 collaboration

Makoy Samuel Yibi Logora 1 collaboration

Cheick Oumar Coulibaly 1 collaboration

Adam Weiss 1 collaboration

Albrecht I Schulte-Hostedde 1 collaboration

Christopher A Cleveland 1 collaboration

Michael J Yabsley 1 collaboration

Ernesto Ruiz-Tiben 1 collaboration

Mark L Eberhard 1 collaboration

C Walsh 1 collaboration

P Tafforeau 1 collaboration

Willi L Wagner 1 collaboration

D J Jafree 1 collaboration

A Bellier 1 collaboration

C Werlein 1 collaboration

M P Kühnel 1 collaboration

E Boller 1 collaboration

S Walker-Samuel 1 collaboration

J L Robertus 1 collaboration

D A Long 1 collaboration

J Jacob 1 collaboration

S Marussi 1 collaboration

E Brown 1 collaboration

D D Jonigk 1 collaboration

M Ackermann 1 collaboration

P D Lee 1 collaboration

Thomas Crellen 1 collaboration

Poppy H L Lamberton 1 collaboration

Narcis B Kabatereine 1 collaboration

Edridah M Tukahebwa 1 collaboration

Moses Adriko 1 collaboration

Joanne P Webster 1 collaboration

Luisa Moretto 1 collaboration

Rachel Heylen 1 collaboration

Steven Vance 1 collaboration

R William Broadhurst 1 collaboration

Matías Gastón Pérez 1 collaboration

Natalia Rego 1 collaboration

Natalia Macchiaroli 1 collaboration

Marcela Alejandra Cucher 1 collaboration

Tushabe John Vianney 1 collaboration

Joel Serubanja 1 collaboration

Prossy Kabuubi Nakawungu 1 collaboration

Fred Besigye 1 collaboration

Richard E Sanya 1 collaboration

Emily L Webb 1 collaboration

Alison M Elliott 1 collaboration

Alison Morrison 1 collaboration

Alistair Antonopoulos 1 collaboration

Ilona Flis 1 collaboration

Sue Howell 1 collaboration

Jennifer McIntyre 1 collaboration

Andy Tait 1 collaboration

Barbara Mable 1 collaboration

Ray Kaplan 1 collaboration

Frederick A Partridge 1 collaboration

María Adelaida Duque-Correa 1 collaboration

Simon Clare 1 collaboration

Lisa Seymour 1 collaboration

Cordelia Brandt 1 collaboration

Tapoka T Mkandawire 1 collaboration

Marina Nick 1 collaboration

Anwen E Brown 1 collaboration

Sirapat Tonitiwong 1 collaboration

David B Sattelle 1 collaboration

Michaela Herz 1 collaboration

Magdalena Zarowiecki 1 collaboration

Leonie Wessels 1 collaboration

Katharina Pätzel 1 collaboration

Ruth Herrmann 1 collaboration

Christiane Braun 1 collaboration

Monika Bergmann 1 collaboration

Uriel Koziol 1 collaboration

G Sallé 1 collaboration

S R Doyle 1 collaboration

J Cortet 1 collaboration

J Cabaret 1 collaboration

M Berriman 1 collaboration

J A Cotton 1 collaboration

Christopher J R Illingworth 1 collaboration

David J Bartley 1 collaboration

Alison A Morrison 1 collaboration

Andrew Rezansoff 1 collaboration

Kate A Rawlinson 1 collaboration

Adam J Reid 1 collaboration

Zhigang Lu 1 collaboration

Patrick Driguez 1 collaboration

Anna Wawer 1 collaboration

Carmen Diaz Soria 1 collaboration

Mandy Sanders 1 collaboration

Karl F Hoffmann 1 collaboration

David Wilcockson 1 collaboration

María Eugenia Ancarola 1 collaboration

Gabriel Lichtenstein 1 collaboration

Johannes Herbig 1 collaboration

Mara Mariconti 1 collaboration

Enrico Brunetti 1 collaboration

Krystyna Albrecht 1 collaboration

Antonio Marcilla 1 collaboration

Marcela Cucher 1 collaboration

Maxime Berg 1 collaboration

Claire Walsh 1 collaboration

Hannah West 1 collaboration

Simon Walker-Samuel 1 collaboration

Rebecca Shipley 1 collaboration