Nathan Mbong

Affiliations

Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

Publications (5)

Multiomic Profiling of Central Nervous System Leukemia Identifies mRNA Translation as a Therapeutic Target.

Blood cancer discovery

Avec: Robert J Vanner , Stephanie M Dobson , Olga I Gan , Jessica McLeod , Erwin M Schoof , Ildiko Grandal , Jeff A Wintersinger , Laura Garcia-Prat , Mohsen Hosseini , Stephanie Z Xie , Liqing Jin , Nathan Mbong , Veronique Voisin , Michelle Chan-Seng-Yue , James A Kennedy , Esmé Waanders , Quaid Morris , Bo Porse , Steven M Chan , Cynthia J Guidos , Jayne S Danska , Mark D Minden , Charles G Mullighan , John E Dick

CC-90009, a novel cereblon E3 ligase modulator, targets acute myeloid leukemia blasts and leukemia stem cells.

Blood

Avec: Christine Surka , Liqing Jin , Nathan Mbong , Chin-Chun Lu , In Sock Jang , Emily Rychak , Derek Mendy , Thomas Clayton , Elizabeth Tindall , Christy Hsu , Celia Fontanillo , Eileen Tran , Adrian Contreras , Stanley W K Ng , Mary Matyskiela , Kai Wang , Philip Chamberlain , Brian Cathers , James Carmichael , Joshua Hansen , Jean C Y Wang , Mark D Minden , Jinhong Fan , Daniel W Pierce , Michael Pourdehnad , Mark Rolfe , Antonia Lopez-Girona , John E Dick , Gang Lu

Identification of the global miR-130a targetome reveals a role for TBL1XR1 in hematopoietic stem cell self-renewal and t(8;21) AML.

Cell reports

Avec: Gabriela Krivdova , Veronique Voisin , Erwin M Schoof , Sajid A Marhon , Alex Murison , Jessica L McLeod , Martino M Gabra , Andy G X Zeng , Stefan Aigner , Brian A Yee , Alexander A Shishkin , Eric L Van Nostrand , Karin G Hermans , Aaron C Trotman-Grant , Nathan Mbong , James A Kennedy , Olga I Gan , Elvin Wagenblast , Daniel D De Carvalho , Leonardo Salmena , Mark D Minden , Gary D Bader , Gene W Yeo , John E Dick , Eric R Lechman

KDM6 demethylases integrate DNA repair gene regulation and loss of KDM6A sensitizes human acute myeloid leukemia to PARP and BCL2 inhibition.

Leukemia

Avec: Liberalis Debraj Boila , Subhadeep Ghosh , Subham K Bandyopadhyay , Liqing Jin , Alex Murison , Andy G X Zeng , Wasim Shaikh , Satyaki Bhowmik , Siva Sai Naga Anurag Muddineni , Mayukh Biswas , Sayantani Sinha , Shankha Subhra Chatterjee , Nathan Mbong , Olga I Gan , Anwesha Bose , Sayan Chakraborty , Andrea Arruda , James A Kennedy , Amanda Mitchell , Eric R Lechman , Debasis Banerjee , Michael Milyavsky , Mark D Minden , John E Dick , Amitava Sengupta

A primary hierarchically organized patient-derived model enables in depth interrogation of stemness driven by the coding and non-coding genome.

Leukemia

Avec: Héléna Boutzen , Seyed Ali Madani Tonekaboni , Michelle Chan-Seng-Yue , Alex Murison , Naoya Takayama , Nathan Mbong , Elvin Wagenblast , Elias Orouji , Andrea Arruda , Amanda Mitchell , Faiyaz Notta , Mark D Minden , Mathieu Lupien , Kerstin B Kaufmann , John E Dick

Réseau de co-auteurs

Mark D Minden 5 collaborations

John E Dick 5 collaborations

Olga I Gan 3 collaborations

Liqing Jin 3 collaborations

James A Kennedy 3 collaborations

Alex Murison 3 collaborations

Erwin M Schoof 2 collaborations

Veronique Voisin 2 collaborations

Michelle Chan-Seng-Yue 2 collaborations

Andy G X Zeng 2 collaborations

Elvin Wagenblast 2 collaborations

Eric R Lechman 2 collaborations

Andrea Arruda 2 collaborations

Amanda Mitchell 2 collaborations

Robert J Vanner 1 collaboration

Stephanie M Dobson 1 collaboration

Jessica McLeod 1 collaboration

Ildiko Grandal 1 collaboration

Jeff A Wintersinger 1 collaboration

Laura Garcia-Prat 1 collaboration

Mohsen Hosseini 1 collaboration

Stephanie Z Xie 1 collaboration

Esmé Waanders 1 collaboration

Quaid Morris 1 collaboration

Bo Porse 1 collaboration

Steven M Chan 1 collaboration

Cynthia J Guidos 1 collaboration

Jayne S Danska 1 collaboration

Charles G Mullighan 1 collaboration

Christine Surka 1 collaboration

Chin-Chun Lu 1 collaboration

In Sock Jang 1 collaboration

Emily Rychak 1 collaboration

Derek Mendy 1 collaboration

Thomas Clayton 1 collaboration

Elizabeth Tindall 1 collaboration

Christy Hsu 1 collaboration

Celia Fontanillo 1 collaboration

Eileen Tran 1 collaboration

Adrian Contreras 1 collaboration

Stanley W K Ng 1 collaboration

Mary Matyskiela 1 collaboration

Kai Wang 1 collaboration

Philip Chamberlain 1 collaboration

Brian Cathers 1 collaboration

James Carmichael 1 collaboration

Joshua Hansen 1 collaboration

Jean C Y Wang 1 collaboration

Jinhong Fan 1 collaboration

Daniel W Pierce 1 collaboration

Michael Pourdehnad 1 collaboration

Mark Rolfe 1 collaboration

Antonia Lopez-Girona 1 collaboration

Gang Lu 1 collaboration

Gabriela Krivdova 1 collaboration

Sajid A Marhon 1 collaboration

Jessica L McLeod 1 collaboration

Martino M Gabra 1 collaboration

Stefan Aigner 1 collaboration

Brian A Yee 1 collaboration

Alexander A Shishkin 1 collaboration

Eric L Van Nostrand 1 collaboration

Karin G Hermans 1 collaboration

Aaron C Trotman-Grant 1 collaboration

Daniel D De Carvalho 1 collaboration

Leonardo Salmena 1 collaboration

Gary D Bader 1 collaboration

Gene W Yeo 1 collaboration

Liberalis Debraj Boila 1 collaboration

Subhadeep Ghosh 1 collaboration

Subham K Bandyopadhyay 1 collaboration

Wasim Shaikh 1 collaboration

Satyaki Bhowmik 1 collaboration

Siva Sai Naga Anurag Muddineni 1 collaboration

Mayukh Biswas 1 collaboration

Sayantani Sinha 1 collaboration

Shankha Subhra Chatterjee 1 collaboration

Anwesha Bose 1 collaboration

Sayan Chakraborty 1 collaboration

Debasis Banerjee 1 collaboration

Michael Milyavsky 1 collaboration

Amitava Sengupta 1 collaboration

Héléna Boutzen 1 collaboration

Seyed Ali Madani Tonekaboni 1 collaboration

Naoya Takayama 1 collaboration

Elias Orouji 1 collaboration

Faiyaz Notta 1 collaboration

Mathieu Lupien 1 collaboration

Kerstin B Kaufmann 1 collaboration