Mathieu Lupien

Affiliations
  • Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Department of Medical Biophysics, University of Toronto, Toronto, Ontario, Canada.
  • Princess Margaret Cancer Centre, University Health Network, Toronto, Ontario, Canada.

Publications (43)

Genome-wide germline correlates of the epigenetic landscape of prostate cancer.

Nature medicine
Avec: Kathleen E Houlahan , Yu-Jia Shiah , Alexander Gusev , Jiapei Yuan , Musaddeque Ahmed , Anamay Shetty , Susmita G Ramanand , Cindy Q Yao , Connor Bell , Edward O'Connor , Vincent Huang , Michael Fraser , Lawrence E Heisler , Julie Livingstone , Takafumi N Yamaguchi , Alexandre Rouette , Adrien Foucal , Shadrielle Melijah G Espiritu , Ankit Sinha , Michelle Sam , Lee Timms , Jeremy Johns , Ada Wong , Alex Murison , Michèle Orain , Valérie Picard , Hélène Hovington , Alain Bergeron , Louis Lacombe , Mathieu Lupien , Yves Fradet , Bernard Têtu , John D McPherson , Bogdan Pasaniuc , Thomas Kislinger , Melvin L K Chua , Mark M Pomerantz , Theodorus van der Kwast , Matthew L Freedman , Ram S Mani , Housheng H He , Robert G Bristow , Paul C Boutros

High-resolution structural genomics reveals new therapeutic vulnerabilities in glioblastoma.

Genome research
Avec: Michael J Johnston , Ana Nikolic , Nicoletta Ninkovic , Paul Guilhamon , Florence M G Cavalli , Steven Seaman , Franz J Zemp , John Lee , Aly Abdelkareem , Katrina Ellestad , Alex Murison , Michelle M Kushida , Fiona J Coutinho , Yussanne Ma , Andrew J Mungall , Richard Moore , Marco A Marra , Michael D Taylor , Peter B Dirks , Trevor J Pugh , Sorana Morrissy , Bradley St Croix , Douglas J Mahoney , Mathieu Lupien , Marco Gallo

A chemical toolbox for the study of bromodomains and epigenetic signaling.

Nature communications
Avec: Qin Wu , David Heidenreich , Stanley Zhou , Suzanne Ackloo , Andreas Krämer , Kiran Nakka , Evelyne Lima-Fernandes , Genevieve Deblois , Shili Duan , Ravi N Vellanki , Fengling Li , Masoud Vedadi , Jeffrey Dilworth , Mathieu Lupien , Paul E Brennan , Cheryl H Arrowsmith , Susanne Müller , Oleg Fedorov , Panagis Filippakopoulos , Stefan Knapp

Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas.

Cancer cell
Avec: Brian Krug , Nicolas De Jay , Ashot S Harutyunyan , Shriya Deshmukh , Dylan M Marchione , Paul Guilhamon , Kelsey C Bertrand , Leonie G Mikael , Melissa K McConechy , Carol C L Chen , Sima Khazaei , Robert F Koncar , Sameer Agnihotri , Damien Faury , Benjamin Ellezam , Alexander G Weil , Josie Ursini-Siegel , Daniel D De Carvalho , Peter B Dirks , Peter W Lewis , Paolo Salomoni , Mathieu Lupien , Cheryl Arrowsmith , Paul F Lasko , Benjamin A Garcia , Claudia L Kleinman , Nada Jabado , Stephen C Mack

The Mitochondrial Transacylase, Tafazzin, Regulates for AML Stemness by Modulating Intracellular Levels of Phospholipids.

Cell stem cell
Avec: Ayesh K Seneviratne , Mingjing Xu , Juan J Aristizabal Henao , Val A Fajardo , Zhenyue Hao , Veronique Voisin , G Wei Xu , Rose Hurren , S Kim , Neil MacLean , Xiaoming Wang , Marcela Gronda , Danny Jeyaraju , Yulia Jitkova , Troy Ketela , Michael Mullokandov , David Sharon , Geethu Thomas , Raphaël Chouinard-Watkins , James R Hawley , Caitlin Schafer , Helen Loo Yau , Zaza Khuchua , Ahmed Aman , Rima Al-Awar , Atan Gross , Steven M Claypool , Richard P Bazinet , Mathieu Lupien , Steven Chan , Daniel D De Carvalho , Mark D Minden , Gary D Bader , Ken D Stark , Paul LeBlanc , Aaron D Schimmer

TFEB-mediated endolysosomal activity controls human hematopoietic stem cell fate.

Cell stem cell
Avec: Laura García-Prat , Kerstin B Kaufmann , Florin Schneiter , Veronique Voisin , Alex Murison , Jocelyn Chen , Michelle Chan-Seng-Yue , Olga I Gan , Jessica L McLeod , Sabrina A Smith , Michelle C Shoong , Darrien Parris , Kristele Pan , Andy G X Zeng , Gabriela Krivdova , Kinam Gupta , Shin-Ichiro Takayanagi , Elvin Wagenblast , Weijia Wang , Mathieu Lupien , Timm Schroeder , Stephanie Z Xie , John E Dick

Copy-scAT: Deconvoluting single-cell chromatin accessibility of genetic subclones in cancer.

Science advances
Avec: Ana Nikolic , Divya Singhal , Katrina Ellestad , Michael Johnston , Yaoqing Shen , Aaron Gillmor , Sorana Morrissy , J Gregory Cairncross , Steven Jones , Mathieu Lupien , Jennifer A Chan , Paola Neri , Nizar Bahlis , Marco Gallo

ecDNAs personify cancer gangsters.

Molecular cell
Avec: Tina Keshavarzian , Mathieu Lupien

The chromatin and single-cell transcriptional landscapes of CD4 T cells in inflammatory bowel disease link risk loci with a proinflammatory Th17 cell population.

Frontiers in immunology
Avec: Tiago S Medina , Alex Murison , Michelle Smith , Gabriela S Kinker , Ankur Chakravarthy , Glauco A F Vitiello , Williams Turpin , Shu Yi Shen , Helen L Yau , Olga F Sarmento , William Faubion , Mathieu Lupien , Mark S Silverberg , Cheryl H Arrowsmith , Daniel D De Carvalho

Candidate Cancer Driver Mutations in Distal Regulatory Elements and Long-Range Chromatin Interaction Networks.

Molecular cell
Avec: Helen Zhu , Liis Uusküla-Reimand , Keren Isaev , Lina Wadi , Azad Alizada , Shimin Shuai , Vincent Huang , Dike Aduluso-Nwaobasi , Marta Paczkowska , Diala Abd-Rabbo , Oliver Ocsenas , Minggao Liang , J Drew Thompson , Yao Li , Luyao Ruan , Michal Krassowski , Irakli Dzneladze , Jared T Simpson , Mathieu Lupien , Lincoln D Stein , Paul C Boutros , Michael D Wilson , Jüri Reimand

Mutations in Noncoding

Molecular cancer research : MCR
Avec: Samah El Ghamrasni , Rene Quevedo , James Hawley , Parisa Mazrooei , Youstina Hanna , Iulia Cirlan , Helen Zhu , Jeff P Bruce , Leslie E Oldfield , S Y Cindy Yang , Paul Guilhamon , Jüri Reimand , Dave W Cescon , Susan J Done , Mathieu Lupien , Trevor J Pugh

PRMT inhibition induces a viral mimicry response in triple-negative breast cancer.

Nature chemical biology
Avec: Qin Wu , David Y Nie , Wail Ba-Alawi , YiShuai Ji , ZiWen Zhang , Jennifer Cruickshank , Jillian Haight , Felipe E Ciamponi , Jocelyn Chen , Shili Duan , Yudao Shen , Jing Liu , Sajid A Marhon , Parinaz Mehdipour , Magdalena M Szewczyk , Nergiz Dogan-Artun , WenJun Chen , Lan Xin Zhang , Genevieve Deblois , Panagiotis Prinos , Katlin B Massirer , Dalia Barsyte-Lovejoy , Jian Jin , Daniel D De Carvalho , Benjamin Haibe-Kains , XiaoJia Wang , David W Cescon , Mathieu Lupien , Cheryl H Arrowsmith

Gradient of Developmental and Injury Response transcriptional states defines functional vulnerabilities underpinning glioblastoma heterogeneity.

Nature cancer
Avec: Laura M Richards , Owen K N Whitley , Graham MacLeod , Florence M G Cavalli , Fiona J Coutinho , Julia E Jaramillo , Nataliia Svergun , Mazdak Riverin , Danielle C Croucher , Michelle Kushida , Kenny Yu , Paul Guilhamon , Naghmeh Rastegar , Moloud Ahmadi , Jasmine K Bhatti , Danielle A Bozek , Naijin Li , Lilian Lee , Clare Che , Erika Luis , Nicole I Park , Zhiyu Xu , Troy Ketela , Richard A Moore , Marco A Marra , Julian Spears , Michael D Cusimano , Sunit Das , Mark Bernstein , Benjamin Haibe-Kains , Mathieu Lupien , H Artee Luchman , Samuel Weiss , Stephane Angers , Peter B Dirks , Gary D Bader , Trevor J Pugh

A noncoding single-nucleotide polymorphism at 8q24 drives

Science (New York, N.Y.)
Avec: Connor Yanchus , Kristen L Drucker , Thomas M Kollmeyer , Ricky Tsai , Warren Winick-Ng , Minggao Liang , Ahmad Malik , Judy Pawling , Silvana B De Lorenzo , Asma Ali , Paul A Decker , Matt L Kosel , Arijit Panda , Khalid N Al-Zahrani , Lingyan Jiang , Jared W L Browning , Chris Lowden , Michael Geuenich , J Javier Hernandez , Jessica T Gosio , Musaddeque Ahmed , Sampath Kumar Loganathan , Jacob Berman , Daniel Trcka , Kulandaimanuvel Antony Michealraj , Jerome Fortin , Brittany Carson , Ethan W Hollingsworth , Sandra Jacinto , Parisa Mazrooei , Lily Zhou , Andrew Elia , Mathieu Lupien , Housheng Hansen He , Daniel J Murphy , Liguo Wang , Alexej Abyzov , James W Dennis , Philipp G Maass , Kieran Campbell , Michael D Wilson , Daniel H Lachance , Margaret Wrensch , John Wiencke , Tak Mak , Len A Pennacchio , Diane E Dickel , Axel Visel , Jeffrey Wrana , Michael D Taylor , Gelareh Zadeh , Peter Dirks , Jeanette E Eckel-Passow , Liliana Attisano , Ana Pombo , Cristiane M Ida , Evgeny Z Kvon , Robert B Jenkins , Daniel Schramek

3-D chromatin conformation, accessibility, and gene expression profiling of triple-negative breast cancer.

BMC genomic data
Avec: Pere Llinàs-Arias , Miquel Ensenyat-Méndez , Javier I J Orozco , Sandra Íñiguez-Muñoz , Betsy Valdez , Chuan Wang , Anja Mezger , Eunkyoung Choi , Yan Zhou Tran , Liqun Yao , Franziska Bonath , Remi-André Olsen , Mattias Ormestad , Manel Esteller , Mathieu Lupien , Diego M Marzese

Chromatin insulation orchestrates matrix metalloproteinase gene cluster expression reprogramming in aggressive breast cancer tumors.

Molecular cancer
Avec: Pere Llinàs-Arias , Miquel Ensenyat-Mendez , Sandra Íñiguez-Muñoz , Javier I J Orozco , Betsy Valdez , Matthew P Salomon , Chikako Matsuba , Maria Solivellas-Pieras , Andrés F Bedoya-López , Borja Sesé , Anja Mezger , Mattias Ormestad , Fernando Unzueta , Siri H Strand , Alexander D Boiko , E Shelley Hwang , Javier Cortés , Maggie L DiNome , Manel Esteller , Mathieu Lupien , Diego M Marzese

Epigenomic heterogeneity as a source of tumour evolution.

Nature reviews. Cancer
Avec: Marthe Laisné , Mathieu Lupien , Céline Vallot

Noncoding mutations target cis-regulatory elements of the FOXA1 plexus in prostate cancer.

Nature communications
Avec: Stanley Zhou , James R Hawley , Fraser Soares , Giacomo Grillo , Mona Teng , Seyed Ali Madani Tonekaboni , Junjie Tony Hua , Ken J Kron , Parisa Mazrooei , Musaddeque Ahmed , Christopher Arlidge , Hwa Young Yun , Julie Livingstone , Vincent Huang , Takafumi N Yamaguchi , Shadrielle M G Espiritu , Yanyun Zhu , Tesa M Severson , Alex Murison , Sarina Cameron , Wilbert Zwart , Theodorus van der Kwast , Trevor J Pugh , Michael Fraser , Paul C Boutros , Robert G Bristow , Housheng Hansen He , Mathieu Lupien

Telomere dysfunction cooperates with epigenetic alterations to impair murine embryonic stem cell fate commitment.

eLife
Avec: Mélanie Criqui , Aditi Qamra , Tsz Wai Chu , Monika Sharma , Julissa Tsao , Danielle A Henry , Dalia Barsyte-Lovejoy , Cheryl H Arrowsmith , Neil Winegarden , Mathieu Lupien , Lea Harrington

Disrupting Mitochondrial Copper Distribution Inhibits Leukemic Stem Cell Self-Renewal.

Cell stem cell
Avec: Rashim Pal Singh , Danny V Jeyaraju , Veronique Voisin , Rose Hurren , Changjiang Xu , James R Hawley , Samir H Barghout , Dilshad H Khan , Marcela Gronda , Xiaoming Wang , Yulia Jitkova , David Sharon , Sanduni Liyanagae , Neil MacLean , Ayesh K Seneviratene , Sara Mirali , Adina Borenstein , Geethu E Thomas , Joelle Soriano , Elias Orouji , Mark D Minden , Andrea Arruda , Steven M Chan , Gary D Bader , Mathieu Lupien , Aaron D Schimmer

Characterization of inv(3) cell line OCI-AML-20 with stroma-dependent CD34 expression.

Experimental hematology
Avec: Genna M Luciani , Lihua Xie , David Dilworth , Anne Tierens , Yoni Moskovitz , Alex Murison , Magdalena M Szewczyk , Amanda Mitchell , Mathieu Lupien , Liran Shlush , John E Dick , Cheryl H Arrowsmith , Dalia Barsyte-Lovejoy , Mark D Minden

Reorganization of the 3D Genome Pinpoints Noncoding Drivers of Primary Prostate Tumors.

Cancer research
Avec: James R Hawley , Stanley Zhou , Christopher Arlidge , Giacomo Grillo , Ken J Kron , Rupert Hugh-White , Theodorus H van der Kwast , Michael Fraser , Paul C Boutros , Robert G Bristow , Mathieu Lupien

Pioneer of prostate cancer: past, present and the future of FOXA1.

Protein & cell
Avec: Mona Teng , Stanley Zhou , Changmeng Cai , Mathieu Lupien , Housheng Hansen He

Cancer-associated chromatin variants uncover the oncogenic role of transposable elements.

Current opinion in genetics & development
Avec: Giacomo Grillo , Mathieu Lupien

Transposable Elements Are Co-opted as Oncogenic Regulatory Elements by Lineage-Specific Transcription Factors in Prostate Cancer.

Cancer discovery
Avec: Giacomo Grillo , Tina Keshavarzian , Simon Linder , Christopher Arlidge , Lisanne Mout , Ankita Nand , Mona Teng , Aditi Qamra , Stanley Zhou , Ken J Kron , Alex Murison , James R Hawley , Michael Fraser , Theodorus H van der Kwast , Ganesh V Raj , Housheng Hansen He , Wilbert Zwart , Mathieu Lupien

Detection of metabolic adaptation in a triple-negative breast cancer animal model with [

European journal of nuclear medicine and molecular imaging
Avec: Andres A Kohan , Mathieu Lupien , David Cescon , Geneviève Deblois , Manuela Ventura , Ur Metser , Patrick Veit-Haibach

Human papillomavirus integration transforms chromatin to drive oncogenesis.

Genome biology
Avec: Mehran Karimzadeh , Christopher Arlidge , Ariana Rostami , Mathieu Lupien , Scott V Bratman , Michael M Hoffman

Integrated analyses highlight interactions between the three-dimensional genome and DNA, RNA and epigenomic alterations in metastatic prostate cancer.

Nature genetics
Avec: Shuang G Zhao , Matthew Bootsma , Stanley Zhou , Raunak Shrestha , Thaidy Moreno-Rodriguez , Arian Lundberg , Chu Pan , Christopher Arlidge , James R Hawley , Adam Foye , Alana S Weinstein , Martin Sjöström , Meng Zhang , Haolong Li , Lisa N Chesner , Nicholas R Rydzewski , Kyle T Helzer , Yue Shi , Auteur inconnu , Molly Lynch , Scott M Dehm , Joshua M Lang , Joshi J Alumkal , Hansen H He , Alexander W Wyatt , Rahul Aggarwal , Wilbert Zwart , Eric J Small , David A Quigley , Mathieu Lupien , Felix Y Feng

An Atlas of Accessible Chromatin in Advanced Prostate Cancer Reveals the Epigenetic Evolution during Tumor Progression.

Cancer research
Avec: Raunak Shrestha , Lisa N Chesner , Meng Zhang , Stanley Zhou , Adam Foye , Arian Lundberg , Alana S Weinstein , Martin Sjöström , Xiaolin Zhu , Thaidy Moreno-Rodriguez , Haolong Li , Su C/Pcf West Coast Prostate Cancer Dream Team , Joshi J Alumkal , Rahul Aggarwal , Eric J Small , Mathieu Lupien , David A Quigley , Felix Y Feng

TULIPs decorate the three-dimensional genome of PFA ependymoma.

Cell
Avec: Michael J Johnston , John J Y Lee , Bo Hu , Ana Nikolic , Elham Hasheminasabgorji , Audrey Baguette , Seungil Paik , Haifen Chen , Sachin Kumar , Carol C L Chen , Selin Jessa , Polina Balin , Vernon Fong , Melissa Zwaig , Kulandaimanuvel Antony Michealraj , Xun Chen , Yanlin Zhang , Srinidhi Varadharajan , Pierre Billon , Nikoleta Juretic , Craig Daniels , Amulya Nageswara Rao , Caterina Giannini , Eric M Thompson , Miklos Garami , Peter Hauser , Timea Pocza , Young Shin Ra , Byung-Kyu Cho , Seung-Ki Kim , Kyu-Chang Wang , Ji Yeoun Lee , Wieslawa Grajkowska , Marta Perek-Polnik , Sameer Agnihotri , Stephen Mack , Benjamin Ellezam , Alex Weil , Jeremy Rich , Guillaume Bourque , Jennifer A Chan , V Wee Yong , Mathieu Lupien , Jiannis Ragoussis , Claudia Kleinman , Jacek Majewski , Mathieu Blanchette , Nada Jabado , Michael D Taylor , Marco Gallo

Identification of leukemia stem cell subsets with distinct transcriptional, epigenetic and functional properties.

Leukemia
Avec: Héléna Boutzen , Alex Murison , Alexa Oriecuia , Suraj Bansal , Christopher Arlidge , Jean C Y Wang , Mathieu Lupien , Kerstin B Kaufmann , John E Dick

Functional Enhancers Shape Extrachromosomal Oncogene Amplifications.

Cell
Avec: Andrew R Morton , Nergiz Dogan-Artun , Zachary J Faber , Graham MacLeod , Cynthia F Bartels , Megan S Piazza , Kevin C Allan , Stephen C Mack , Xiuxing Wang , Ryan C Gimple , Qiulian Wu , Brian P Rubin , Shashirekha Shetty , Stephane Angers , Peter B Dirks , Richard C Sallari , Mathieu Lupien , Jeremy N Rich , Peter C Scacheri

Cistrome Partitioning Reveals Convergence of Somatic Mutations and Risk Variants on Master Transcription Regulators in Primary Prostate Tumors.

Cancer cell
Avec: Parisa Mazrooei , Ken J Kron , Yanyun Zhu , Stanley Zhou , Giacomo Grillo , Tahmid Mehdi , Musaddeque Ahmed , Tesa M Severson , Paul Guilhamon , Nicholas Sinnott Armstrong , Vincent Huang , Takafumi N Yamaguchi , Michael Fraser , Theodorus van der Kwast , Paul C Boutros , Housheng Hansen He , Andries M Bergman , Robert G Bristow , Wilbert Zwart , Mathieu Lupien

Targeting bivalency de-represses Indian Hedgehog and inhibits self-renewal of colorectal cancer-initiating cells.

Nature communications
Avec: Evelyne Lima-Fernandes , Alex Murison , Tiago da Silva Medina , Yadong Wang , Anqi Ma , Cherry Leung , Genna M Luciani , Jennifer Haynes , Aaron Pollett , Constanze Zeller , Shili Duan , Antonija Kreso , Dalia Barsyte-Lovejoy , Bradly G Wouters , Jian Jin , Daniel D De Carvalho , Mathieu Lupien , Cheryl H Arrowsmith , Catherine A O'Brien

Identifying clusters of

Genome research
Avec: Seyed Ali Madani Tonekaboni , Parisa Mazrooei , Victor Kofia , Benjamin Haibe-Kains , Mathieu Lupien

The Proteogenomic Landscape of Curable Prostate Cancer.

Cancer cell
Avec: Ankit Sinha , Vincent Huang , Julie Livingstone , Jenny Wang , Natalie S Fox , Natalie Kurganovs , Vladimir Ignatchenko , Katharina Fritsch , Nilgun Donmez , Lawrence E Heisler , Yu-Jia Shiah , Cindy Q Yao , Javier A Alfaro , Stas Volik , Anna Lapuk , Michael Fraser , Ken Kron , Alex Murison , Mathieu Lupien , Cenk Sahinalp , Colin C Collins , Bernard Tetu , Mehdi Masoomian , David M Berman , Theodorus van der Kwast , Robert G Bristow , Thomas Kislinger , Paul C Boutros

C3D: a tool to predict 3D genomic interactions between cis-regulatory elements.

Bioinformatics (Oxford, England)
Avec: Tahmid Mehdi , Swneke D Bailey , Paul Guilhamon , Mathieu Lupien

Metabolic Regulation of the Epigenome Drives Lethal Infantile Ependymoma.

Cell
Avec: Kulandaimanuvel Antony Michealraj , Sachin A Kumar , Leo J Y Kim , Florence M G Cavalli , David Przelicki , John B Wojcik , Alberto Delaidelli , Andrea Bajic , Olivier Saulnier , Graham MacLeod , Ravi N Vellanki , Maria C Vladoiu , Paul Guilhamon , Winnie Ong , John J Y Lee , Yanqing Jiang , Borja L Holgado , Alex Rasnitsyn , Ahmad A Malik , Ricky Tsai , Cory M Richman , Kyle Juraschka , Joonas Haapasalo , Evan Y Wang , Pasqualino De Antonellis , Hiromichi Suzuki , Hamza Farooq , Polina Balin , Kaitlin Kharas , Randy Van Ommeren , Olga Sirbu , Avesta Rastan , Stacey L Krumholtz , Michelle Ly , Moloud Ahmadi , Geneviève Deblois , Dilakshan Srikanthan , Betty Luu , James Loukides , Xiaochong Wu , Livia Garzia , Vijay Ramaswamy , Evgeny Kanshin , María Sánchez-Osuna , Ibrahim El-Hamamy , Fiona J Coutinho , Panagiotis Prinos , Sheila Singh , Laura K Donovan , Craig Daniels , Daniel Schramek , Mike Tyers , Samuel Weiss , Lincoln D Stein , Mathieu Lupien , Bradly G Wouters , Benjamin A Garcia , Cheryl H Arrowsmith , Poul H Sorensen , Stephane Angers , Nada Jabado , Peter B Dirks , Stephen C Mack , Sameer Agnihotri , Jeremy N Rich , Michael D Taylor

Author Correction: Human somatic cell mutagenesis creates genetically tractable sarcomas.

Nature genetics
Avec: Sam D Molyneux , Paul D Waterhouse , Dawne Shelton , Yang W Shao , Christopher M Watling , Qing-Lian Tang , Isaac S Harris , Brendan C Dickson , Pirashaanthy Tharmapalan , Geir K Sandve , Xiaoyang Zhang , Swneke D Bailey , Hal Berman , Jay S Wunder , Zsuzsanna Izsvák , Mathieu Lupien , Tak W Mak , Rama Khokha

The Transition from Quiescent to Activated States in Human Hematopoietic Stem Cells Is Governed by Dynamic 3D Genome Reorganization.

Cell stem cell
Avec: Naoya Takayama , Alex Murison , Shin-Ichiro Takayanagi , Christopher Arlidge , Stanley Zhou , Laura Garcia-Prat , Michelle Chan-Seng-Yue , Sasan Zandi , Olga I Gan , Héléna Boutzen , Kerstin B Kaufmann , Aaron Trotman-Grant , Erwin Schoof , Ken Kron , Noelia Díaz , John J Y Lee , Tiago Medina , Daniel D De Carvalho , Michael D Taylor , Juan M Vaquerizas , Stephanie Z Xie , John E Dick , Mathieu Lupien

Large organized chromatin lysine domains help distinguish primitive from differentiated cell populations.

Nature communications
Avec: Seyed Ali Madani Tonekaboni , Benjamin Haibe-Kains , Mathieu Lupien

In vivo CRISPR screens identify a dual function of MEN1 in regulating tumor-microenvironment interactions.

Nature genetics
Avec: Peiran Su , Yin Liu , Tianyi Chen , Yibo Xue , Yong Zeng , Guanghui Zhu , Sujun Chen , Mona Teng , Xinpei Ci , Mengdi Guo , Michael Y He , Jun Hao , Vivian Chu , Wenxi Xu , Shiyan Wang , Parinaz Mehdipour , Xin Xu , Sajid A Marhon , Fraser Soares , Nhu-An Pham , Bell Xi Wu , Peter Hyunwuk Her , Shengrui Feng , Najd Alshamlan , Maryam Khalil , Rehna Krishnan , Fangyou Yu , Chang Chen , Francis Burrows , Razqallah Hakem , Mathieu Lupien , Shane Harding , Benjamin H Lok , Catherine O'Brien , Alejandro Berlin , Daniel D De Carvalho , David G Brooks , Daniel Schramek , Ming-Sound Tsao , Housheng Hansen He

GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer.

Nature communications
Avec: Qin Wu , Wail Ba-Alawi , Genevieve Deblois , Jennifer Cruickshank , Shili Duan , Evelyne Lima-Fernandes , Jillian Haight , Seyed Ali Madani Tonekaboni , Anne-Marie Fortier , Hellen Kuasne , Trevor D McKee , Hassan Mahmoud , Michelle Kushida , Sarina Cameron , Nergiz Dogan-Artun , WenJun Chen , Yan Nie , Lan Xin Zhang , Ravi N Vellanki , Stanley Zhou , Panagiotis Prinos , Bradly G Wouters , Peter B Dirks , Susan J Done , Morag Park , David W Cescon , Benjamin Haibe-Kains , Mathieu Lupien , Cheryl H Arrowsmith

Réseau de co-auteurs

Alex Murison 11 collaborations
Stanley Zhou 10 collaborations
Cheryl H Arrowsmith 8 collaborations
Paul Guilhamon 7 collaborations
Daniel D De Carvalho 7 collaborations
Christopher Arlidge 7 collaborations
Michael Fraser 6 collaborations
Paul C Boutros 6 collaborations
Peter B Dirks 6 collaborations
James R Hawley 6 collaborations
Housheng Hansen He 6 collaborations
Vincent Huang 5 collaborations
Robert G Bristow 5 collaborations
Michael D Taylor 5 collaborations
Parisa Mazrooei 5 collaborations
Benjamin Haibe-Kains 5 collaborations
Giacomo Grillo 5 collaborations
Musaddeque Ahmed 4 collaborations
Theodorus van der Kwast 4 collaborations
Trevor J Pugh 4 collaborations
Shili Duan 4 collaborations
John E Dick 4 collaborations
Dalia Barsyte-Lovejoy 4 collaborations
Mona Teng 4 collaborations
Seyed Ali Madani Tonekaboni 4 collaborations
Ken J Kron 4 collaborations
Wilbert Zwart 4 collaborations
Julie Livingstone 3 collaborations
Takafumi N Yamaguchi 3 collaborations
Ana Nikolic 3 collaborations
Florence M G Cavalli 3 collaborations
Fiona J Coutinho 3 collaborations
Marco Gallo 3 collaborations
Qin Wu 3 collaborations
Evelyne Lima-Fernandes 3 collaborations
Genevieve Deblois 3 collaborations
Ravi N Vellanki 3 collaborations
Sameer Agnihotri 3 collaborations
Nada Jabado 3 collaborations
Stephen C Mack 3 collaborations
Veronique Voisin 3 collaborations
Mark D Minden 3 collaborations
Gary D Bader 3 collaborations
Kerstin B Kaufmann 3 collaborations
Nergiz Dogan-Artun 3 collaborations
Panagiotis Prinos 3 collaborations
Graham MacLeod 3 collaborations
Stephane Angers 3 collaborations
Kulandaimanuvel Antony Michealraj 3 collaborations
Daniel Schramek 3 collaborations
John J Y Lee 3 collaborations
Bradly G Wouters 3 collaborations
Yu-Jia Shiah 2 collaborations
Cindy Q Yao 2 collaborations
Lawrence E Heisler 2 collaborations
Ankit Sinha 2 collaborations
Thomas Kislinger 2 collaborations
Michael J Johnston 2 collaborations
Katrina Ellestad 2 collaborations
Marco A Marra 2 collaborations
Sorana Morrissy 2 collaborations
Carol C L Chen 2 collaborations
Benjamin Ellezam 2 collaborations
Benjamin A Garcia 2 collaborations
Rose Hurren 2 collaborations
Neil MacLean 2 collaborations
Xiaoming Wang 2 collaborations
Marcela Gronda 2 collaborations
Yulia Jitkova 2 collaborations
Troy Ketela 2 collaborations
David Sharon 2 collaborations
Aaron D Schimmer 2 collaborations
Jocelyn Chen 2 collaborations
Michelle Chan-Seng-Yue 2 collaborations
Olga I Gan 2 collaborations
Shin-Ichiro Takayanagi 2 collaborations
Stephanie Z Xie 2 collaborations
Jennifer A Chan 2 collaborations
Tina Keshavarzian 2 collaborations
Helen Zhu 2 collaborations
Minggao Liang 2 collaborations
Lincoln D Stein 2 collaborations
Michael D Wilson 2 collaborations
Jüri Reimand 2 collaborations
Susan J Done 2 collaborations
Wail Ba-Alawi 2 collaborations
Jennifer Cruickshank 2 collaborations
Jillian Haight 2 collaborations
Sajid A Marhon 2 collaborations
Parinaz Mehdipour 2 collaborations
Magdalena M Szewczyk 2 collaborations
WenJun Chen 2 collaborations
Lan Xin Zhang 2 collaborations
Jian Jin 2 collaborations
David W Cescon 2 collaborations
Michelle Kushida 2 collaborations
Moloud Ahmadi 2 collaborations
Samuel Weiss 2 collaborations
Ricky Tsai 2 collaborations
Pere Llinàs-Arias 2 collaborations
Javier I J Orozco 2 collaborations
Sandra Íñiguez-Muñoz 2 collaborations
Betsy Valdez 2 collaborations
Anja Mezger 2 collaborations
Mattias Ormestad 2 collaborations
Manel Esteller 2 collaborations
Diego M Marzese 2 collaborations
Fraser Soares 2 collaborations
Yanyun Zhu 2 collaborations
Tesa M Severson 2 collaborations
Sarina Cameron 2 collaborations
Aditi Qamra 2 collaborations
Genna M Luciani 2 collaborations
Theodorus H van der Kwast 2 collaborations
Geneviève Deblois 2 collaborations
Raunak Shrestha 2 collaborations
Thaidy Moreno-Rodriguez 2 collaborations
Arian Lundberg 2 collaborations
Adam Foye 2 collaborations
Alana S Weinstein 2 collaborations
Martin Sjöström 2 collaborations
Meng Zhang 2 collaborations
Haolong Li 2 collaborations
Lisa N Chesner 2 collaborations
Joshi J Alumkal 2 collaborations
Rahul Aggarwal 2 collaborations
Eric J Small 2 collaborations
David A Quigley 2 collaborations
Felix Y Feng 2 collaborations
Polina Balin 2 collaborations
Craig Daniels 2 collaborations
Héléna Boutzen 2 collaborations
Jeremy N Rich 2 collaborations
Tahmid Mehdi 2 collaborations
Ken Kron 2 collaborations
Swneke D Bailey 2 collaborations
Kathleen E Houlahan 1 collaboration
Alexander Gusev 1 collaboration
Jiapei Yuan 1 collaboration
Anamay Shetty 1 collaboration
Susmita G Ramanand 1 collaboration
Connor Bell 1 collaboration
Edward O'Connor 1 collaboration
Alexandre Rouette 1 collaboration
Adrien Foucal 1 collaboration
Shadrielle Melijah G Espiritu 1 collaboration
Michelle Sam 1 collaboration
Lee Timms 1 collaboration
Jeremy Johns 1 collaboration
Ada Wong 1 collaboration
Michèle Orain 1 collaboration
Valérie Picard 1 collaboration
Hélène Hovington 1 collaboration
Alain Bergeron 1 collaboration
Louis Lacombe 1 collaboration
Yves Fradet 1 collaboration
Bernard Têtu 1 collaboration
John D McPherson 1 collaboration
Bogdan Pasaniuc 1 collaboration
Melvin L K Chua 1 collaboration
Mark M Pomerantz 1 collaboration
Matthew L Freedman 1 collaboration
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