Neil Parrott

Affiliations

Pharmaceutical Sciences, Roche Pharma Research and Early Development, Roche Innovation Centre Basel, Basel, Switzerland.

Publications (12)

Characterization of the Ontogeny of Hepatic UDP-Glucuronosyltransferase Enzymes Based on Glucuronidation Activity Measured in Human Liver Microsomes.

Journal of clinical pharmacology

Avec: Justine Badée , Nahong Qiu , Abby C Collier , Ryan H Takahashi , William F Forrest , Neil Parrott , Stephan Schmidt , Stephen Fowler

Food Effect Projections via Physiologically Based Pharmacokinetic Modeling: Predictive Case Studies.

Journal of pharmaceutical sciences

Avec: Christophe Tistaert , Tycho Heimbach , Binfeng Xia , Neil Parrott , Tanay S Samant , Filippos Kesisoglou

Global Sensitivity Analysis of the Rodgers and Rowland Model for Prediction of Tissue: Plasma Partitioning Coefficients: Assessment of the Key Physiological and Physicochemical Factors That Determine Small-Molecule Tissue Distribution.

The AAPS journal

Avec: Estelle Yau , Andrés Olivares-Morales , Michael Gertz , Neil Parrott , Adam S Darwich , Leon Aarons , Kayode Ogungbenro

Best Practices in the Development and Validation of Physiologically Based Biopharmaceutics Modeling. A Workshop Summary Report.

Journal of pharmaceutical sciences

Avec: Neil Parrott , Sandra Suarez-Sharp , Filippos Kesisoglou , Shriram M Pathak , David Good , Christian Wagner , André Dallmann , James Mullin , Nikunjkumar Patel , Arian Emami Riedmaier , Amitava Mitra , Kimberly Raines , James Butler , Maziar Kakhi , Min Li , Yang Zhao , Eleftheria Tsakalozou , Talia Flanagan , Jennifer Dressman , Xavier Pepin

In Vitro to In Vivo Extrapolation of Metabolic Clearance for UGT Substrates Using Short-Term Suspension and Long-Term Co-cultured Human Hepatocytes.

The AAPS journal

Avec: Luca Docci , Florian Klammers , Aynur Ekiciler , Birgit Molitor , Kenichi Umehara , Isabelle Walter , Stephan Krähenbühl , Neil Parrott , Stephen Fowler

Characterization of Hepatic UDP-Glucuronosyltransferase Enzyme Abundance-Activity Correlations and Population Variability Using a Proteomics Approach and Comparison with Cytochrome P450 Enzymes.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Ryan H Takahashi , William F Forrest , Alexander D Smith , Justine Badee , NaHong Qiu , Stephan Schmidt , Abby C Collier , Neil Parrott , Stephen Fowler

Estimation of Fraction Metabolized by Cytochrome P450 Enzymes Using Long-Term Cocultured Human Hepatocytes.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Florian Klammers , Andreas Goetschi , Aynur Ekiciler , Isabelle Walter , Neil Parrott , Stephen Fowler , Kenichi Umehara

Design and Measurement of Drug Tissue Concentration Asymmetry and Tissue Exposure-Effect (Tissue PK-PD) Evaluation.

Journal of medicinal chemistry

Avec: Richard Zang , Aline Barth , Harvey Wong , Jan Marik , Jie Shen , Julie Lade , Kerri Grove , Matthew R Durk , Neil Parrott , Patrick J Rudewicz , Sylvia Zhao , Tao Wang , Zhengyin Yan , Donglu Zhang

Gastrointestinal Fluid Volumes in Pediatrics: A Retrospective MRI Study.

Pharmaceutics

Avec: Matthias Van der Veken , Michael Aertsen , Joachim Brouwers , Cordula Stillhart , Neil Parrott , Patrick Augustijns

Current State and Future Expectations of Translational Modeling Strategies to Support Drug Product Development, Manufacturing Changes and Controls: A Workshop Summary Report.

Journal of pharmaceutical sciences

Avec: Xavier J H Pepin , Neil Parrott , Jennifer Dressman , Poonam Delvadia , Amitava Mitra , Xinyuan Zhang , Andrew Babiskin , Vidula Kolhatkar , Sandra Suarez-Sharp

Application of the Extended Clearance Classification System (ECCS) in Drug Discovery and Development: Selection of Appropriate In Vitro Tools and Clearance Prediction.

Drug metabolism and disposition: the biological fate of chemicals

Avec: Kenichi Umehara , Carina Cantrill , Matthias Beat Wittwer , Elisa Di Lenarda , Florian Klammers , Aynur Ekiciler , Neil Parrott , Stephen Fowler , Mohammed Ullah

Impact of gastrointestinal physiology on drug absorption in special populations--An UNGAP review.

European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences

Avec: Cordula Stillhart , Katarina Vučićević , Patrick Augustijns , Abdul W Basit , Hannah Batchelor , Talia R Flanagan , Ina Gesquiere , Rick Greupink , Daniel Keszthelyi , Mikko Koskinen , Christine M Madla , Christophe Matthys , Goran Miljuš , Miriam G Mooij , Neil Parrott , Anna-Lena Ungell , Saskia N de Wildt , Mine Orlu , Sandra Klein , Anette Müllertz

Réseau de co-auteurs

Stephen Fowler 5 collaborations

Florian Klammers 3 collaborations

Aynur Ekiciler 3 collaborations

Kenichi Umehara 3 collaborations

Abby C Collier 2 collaborations

Ryan H Takahashi 2 collaborations

William F Forrest 2 collaborations

Stephan Schmidt 2 collaborations

Filippos Kesisoglou 2 collaborations

Sandra Suarez-Sharp 2 collaborations

Amitava Mitra 2 collaborations

Jennifer Dressman 2 collaborations

Isabelle Walter 2 collaborations

Cordula Stillhart 2 collaborations

Patrick Augustijns 2 collaborations

Justine Badée 1 collaboration

Nahong Qiu 1 collaboration

Christophe Tistaert 1 collaboration

Tycho Heimbach 1 collaboration

Binfeng Xia 1 collaboration

Tanay S Samant 1 collaboration

Estelle Yau 1 collaboration

Andrés Olivares-Morales 1 collaboration

Michael Gertz 1 collaboration

Adam S Darwich 1 collaboration

Leon Aarons 1 collaboration

Kayode Ogungbenro 1 collaboration

Shriram M Pathak 1 collaboration

David Good 1 collaboration

Christian Wagner 1 collaboration

André Dallmann 1 collaboration

James Mullin 1 collaboration

Nikunjkumar Patel 1 collaboration

Arian Emami Riedmaier 1 collaboration

Kimberly Raines 1 collaboration

James Butler 1 collaboration

Maziar Kakhi 1 collaboration

Min Li 1 collaboration

Yang Zhao 1 collaboration

Eleftheria Tsakalozou 1 collaboration

Talia Flanagan 1 collaboration

Xavier Pepin 1 collaboration

Luca Docci 1 collaboration

Birgit Molitor 1 collaboration

Stephan Krähenbühl 1 collaboration

Alexander D Smith 1 collaboration

Justine Badee 1 collaboration

NaHong Qiu 1 collaboration

Andreas Goetschi 1 collaboration

Richard Zang 1 collaboration

Aline Barth 1 collaboration

Harvey Wong 1 collaboration

Jan Marik 1 collaboration

Jie Shen 1 collaboration

Julie Lade 1 collaboration

Kerri Grove 1 collaboration

Matthew R Durk 1 collaboration

Patrick J Rudewicz 1 collaboration

Sylvia Zhao 1 collaboration

Tao Wang 1 collaboration

Zhengyin Yan 1 collaboration

Donglu Zhang 1 collaboration

Matthias Van der Veken 1 collaboration

Michael Aertsen 1 collaboration

Joachim Brouwers 1 collaboration

Xavier J H Pepin 1 collaboration

Poonam Delvadia 1 collaboration

Xinyuan Zhang 1 collaboration

Andrew Babiskin 1 collaboration

Vidula Kolhatkar 1 collaboration

Carina Cantrill 1 collaboration

Matthias Beat Wittwer 1 collaboration

Elisa Di Lenarda 1 collaboration

Mohammed Ullah 1 collaboration

Katarina Vučićević 1 collaboration

Abdul W Basit 1 collaboration

Hannah Batchelor 1 collaboration

Talia R Flanagan 1 collaboration

Ina Gesquiere 1 collaboration

Rick Greupink 1 collaboration

Daniel Keszthelyi 1 collaboration

Mikko Koskinen 1 collaboration

Christine M Madla 1 collaboration

Christophe Matthys 1 collaboration

Goran Miljuš 1 collaboration

Miriam G Mooij 1 collaboration

Anna-Lena Ungell 1 collaboration

Saskia N de Wildt 1 collaboration

Mine Orlu 1 collaboration

Sandra Klein 1 collaboration

Anette Müllertz 1 collaboration