Nima Mosammaparast

Affiliations

Department of Pathology and Immunology, Division of Laboratory and Genomic Medicine, Washington University School of Medicine, St. Louis, MO 63110, USA.

Publications (34)

Perturbing cohesin dynamics drives MRE11 nuclease-dependent replication fork slowing.

Nucleic acids research

Avec: Denisse Carvajal-Maldonado , Andrea K Byrum , Jessica Jackson , Sarah Wessel , Delphine Lemaçon , Laure Guitton-Sert , Annabel Quinet , Stephanie Tirman , Simona Graziano , Jean-Yves Masson , David Cortez , Susana Gonzalo , Nima Mosammaparast , Alessandro Vindigni

The ASCC2 CUE domain in the ALKBH3-ASCC DNA repair complex recognizes adjacent ubiquitins in K63-linked polyubiquitin.

The Journal of biological chemistry

Avec: Patrick M Lombardi , Sara Haile , Timur Rusanov , Rebecca Rodell , Rita Anoh , Julia G Baer , Kate A Burke , Lauren N Gray , Abigail R Hacker , Kayla R Kebreau , Christine K Ngandu , Hannah A Orland , Emmanuella Osei-Asante , Dhane P Schmelyun , Devin E Shorb , Shaheer H Syed , Julianna M Veilleux , Ananya Majumdar , Nima Mosammaparast , Cynthia Wolberger

SMYD3 Impedes Small Cell Lung Cancer Sensitivity to Alkylation Damage through RNF113A Methylation-Phosphorylation Cross-talk.

Cancer discovery

Avec: Valentina Lukinović , Simone Hausmann , Gael S Roth , Clement Oyeniran , Tanveer Ahmad , Ning Tsao , Joshua R Brickner , Alexandre G Casanova , Florent Chuffart , Ana Morales Benitez , Jessica Vayr , Rebecca Rodell , Marianne Tardif , Pascal W T C Jansen , Yohann Couté , Michiel Vermeulen , Pierre Hainaut , Pawel K Mazur , Nima Mosammaparast , Nicolas Reynoird

The debranching enzyme Dbr1 regulates lariat turnover and intron splicing.

Research square

Avec: Luke Buerer , Nathaniel E Clark , Anastasia Welch , Chaorui Duan , Allison J Taggart , Brittany A Townley , Jing Wang , Rachel Soemedi , Stephen Rong , Chien-Ling Lin , Yi Zeng , Adam Katolik , Jonathan P Staley , Masad J Damha , Nima Mosammaparast , William G Fairbrother

The complexity and regulation of repair of alkylation damage to nucleic acids.

Critical reviews in biochemistry and molecular biology

Avec: Ning Tsao , Orlando D Schärer , Nima Mosammaparast

Defining and Modulating 'BRCAness'.

Trends in cell biology

Avec: Andrea K Byrum , Alessandro Vindigni , Nima Mosammaparast

Intersections between transcription-coupled repair and alkylation damage reversal.

DNA repair

Avec: Joshua R Brickner , Brittany A Townley , Nima Mosammaparast

Competitive binding of E3 ligases TRIM26 and WWP2 controls SOX2 in glioblastoma.

Nature communications

Avec: Tatenda Mahlokozera , Bhuvic Patel , Hao Chen , Patrick Desouza , Xuan Qu , Diane D Mao , Daniel Hafez , Wei Yang , Rukayat Taiwo , Mounica Paturu , Afshin Salehi , Amit D Gujar , Gavin P Dunn , Nima Mosammaparast , Allegra A Petti , Hiroko Yano , Albert H Kim

Rapid profiling of DNA replication dynamics using mass spectrometry-based analysis of nascent DNA.

The Journal of cell biology

Avec: Mohamed E Ashour , Andrea K Byrum , Alice Meroni , Jun Xia , Saurabh Singh , Roberto Galletto , Susan M Rosenberg , Alessandro Vindigni , Nima Mosammaparast

Aberrant RNA methylation triggers recruitment of an alkylation repair complex.

Molecular cell

Avec: Ning Tsao , Joshua R Brickner , Rebecca Rodell , Adit Ganguly , Matthew Wood , Clement Oyeniran , Tanveer Ahmad , Hua Sun , Albino Bacolla , Lisheng Zhang , Valentina Lukinović , Jennifer M Soll , Brittany A Townley , Alexandre G Casanova , John A Tainer , Chuan He , Alessandro Vindigni , Nicolas Reynoird , Nima Mosammaparast

The Shu complex prevents mutagenesis and cytotoxicity of single-strand specific alkylation lesions.

eLife

Avec: Braulio Bonilla , Alexander J Brown , Sarah R Hengel , Kyle S Rapchak , Debra Mitchell , Catherine A Pressimone , Adeola A Fagunloye , Thong T Luong , Reagan A Russell , Rudri K Vyas , Tony M Mertz , Hani S Zaher , Nima Mosammaparast , Ewa P Malc , Piotr A Mieczkowski , Steven A Roberts , Kara A Bernstein

RAD51 Foci as a Biomarker Predictive of Platinum Chemotherapy Response in Ovarian Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Amanda J Compadre , Lillian N van Biljon , Mark C Valentine , Alba Llop-Guevara , Emily Graham , Bisiayo Fashemi , Andrea Herencia-Ropero , Emilee N Kotnik , Isaac Cooper , Shariska P Harrington , Lindsay M Kuroki , Carolyn K McCourt , Andrea R Hagemann , Premal H Thaker , David G Mutch , Matthew A Powell , Lulu Sun , Nima Mosammaparast , Violeta Serra , Peinan Zhao , Elena Lomonosova , Dineo Khabele , Mary M Mullen

Nuclease-independent functions of RAG1 direct distinct DNA damage responses in B cells.

EMBO reports

Avec: Rachel Johnston , Brendan Mathias , Stephanie J Crowley , Haley A Schmidt , Lynn S White , Nima Mosammaparast , Abby M Green , Jeffrey J Bednarski

Extended DNA threading through a dual-engine motor module of the activating signal co-integrator 1 complex.

Nature communications

Avec: Junqiao Jia , Tarek Hilal , Katherine E Bohnsack , Aleksandar Chernev , Ning Tsao , Juliane Bethmann , Aruna Arumugam , Lane Parmely , Nicole Holton , Bernhard Loll , Nima Mosammaparast , Markus T Bohnsack , Henning Urlaub , Markus C Wahl

A functional link between lariat debranching enzyme and the intron-binding complex is defective in non-photosensitive trichothiodystrophy.

Molecular cell

Avec: Brittany A Townley , Luke Buerer , Ning Tsao , Albino Bacolla , Fadhel Mansoori , Timur Rusanov , Nathanial Clark , Negar Goodarzi , Nicolas Schmidt , Sridhar Nonavinkere Srivatsan , Hua Sun , Reilly A Sample , Joshua R Brickner , Drew McDonald , Miaw-Sheue Tsai , Matthew J Walter , David F Wozniak , Alex S Holehouse , Vladimir Pena , John A Tainer , William G Fairbrother , Nima Mosammaparast

TCAF1 promotes TRPV2-mediated Ca

Nature communications

Avec: Lingzhen Kong , Chen Cheng , Abigael Cheruiyot , Jiayi Yuan , Yichan Yang , Sydney Hwang , Daniel Foust , Ning Tsao , Emily Wilkerson , Nima Mosammaparast , Michael B Major , David W Piston , Shan Li , Zhongsheng You

Barrier-to-Autointegration Factor 1 Protects against a Basal cGAS-STING Response.

mBio

Avec: Hongming Ma , Wei Qian , Monika Bambouskova , Patrick L Collins , Sofia I Porter , Andrea K Byrum , Rong Zhang , Maxim Artyomov , Eugene M Oltz , Nima Mosammaparast , Jonathan J Miner , Michael S Diamond

XLF and H2AX function in series to promote replication fork stability.

The Journal of cell biology

Avec: Bo-Ruei Chen , Annabel Quinet , Andrea K Byrum , Jessica Jackson , Matteo Berti , Saravanabhavan Thangavel , Andrea L Bredemeyer , Issa Hindi , Nima Mosammaparast , Jessica K Tyler , Alessandro Vindigni , Barry P Sleckman

53BP1 Enforces Distinct Pre- and Post-resection Blocks on Homologous Recombination.

Molecular cell

Avec: Elsa Callen , Dali Zong , Wei Wu , Nancy Wong , Andre Stanlie , Momoko Ishikawa , Raphael Pavani , Lavinia C Dumitrache , Andrea K Byrum , Carlos Mendez-Dorantes , Paula Martinez , Andres Canela , Yaakov Maman , Amanda Day , Michael J Kruhlak , Maria A Blasco , Jeremy M Stark , Nima Mosammaparast , Peter J McKinnon , André Nussenzweig

RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex.

Cell reports

Avec: Deepti Soodgupta , Lynn S White , Wei Yang , Rachel Johnston , Jared M Andrews , Masako Kohyama , Kenneth M Murphy , Nima Mosammaparast , Jacqueline E Payton , Jeffrey J Bednarski

Mechanisms of damage tolerance and repair during DNA replication.

Nucleic acids research

Avec: Mohamed Elsaid Ashour , Nima Mosammaparast

Protocol to analyze and quantify protein-methylated RNA interactions in mammalian cells with a combination of RNA immunoprecipitation and nucleoside mass spectrometry.

STAR protocols

Avec: Ning Tsao , Jennifer M Soll , Nima Mosammaparast

Use of High-Performance Liquid Chromatography-Mass Spectrometry (HPLC-MS) to Quantify Modified Nucleosides.

Methods in molecular biology (Clifton, N.J.)

Avec: Rebecca Rodell , Ning Tsao , Adit Ganguly , Nima Mosammaparast

How RNA impacts DNA repair.

DNA repair

Avec: Ning Tsao , Mohamed E Ashour , Nima Mosammaparast

Mitotic regulators TPX2 and Aurora A protect DNA forks during replication stress by counteracting 53BP1 function.

The Journal of cell biology

Avec: Andrea K Byrum , Denisse Carvajal-Maldonado , Miranda C Mudge , David Valle-Garcia , Mona C Majid , Romil Patel , Mathew E Sowa , Steven P Gygi , J Wade Harper , Yang Shi , Alessandro Vindigni , Nima Mosammaparast

RNA Modifications: Reversal Mechanisms and Cancer.

Biochemistry

Avec: Roopa Thapar , Albino Bacolla , Clement Oyeniran , Joshua R Brickner , Naga Babu Chinnam , Nima Mosammaparast , John A Tainer

Homologous recombination deficiency real-time clinical assays, ready or not?

Gynecologic oncology

Avec: Katherine Fuh , Mary Mullen , Barbara Blachut , Elizabeth Stover , Panagiotis Konstantinopoulos , Joyce Liu , Ursula Matulonis , Dineo Khabele , Nima Mosammaparast , Alessandro Vindigni

GAS6/AXL Inhibition Enhances Ovarian Cancer Sensitivity to Chemotherapy and PARP Inhibition through Increased DNA Damage and Enhanced Replication Stress.

Molecular cancer research : MCR

Avec: Mary M Mullen , Elena Lomonosova , Michael D Toboni , Alyssa Oplt , Emily Cybulla , Barbara Blachut , Peinan Zhao , Hollie Noia , Daniel Wilke , Erinn B Rankin , Lindsay M Kuroki , Andrea R Hagemann , Ian S Hagemann , Carolyn K McCourt , Premal H Thaker , David G Mutch , Matthew A Powell , Nima Mosammaparast , Alessandro Vindigni , Katherine C Fuh

ALKBH3 partner ASCC3 mediates P-body formation and selective clearance of MMS-induced 1-methyladenosine and 3-methylcytosine from mRNA.

Journal of translational medicine

Avec: Kristian Lied Wollen , Lars Hagen , Cathrine B Vågbø , Renana Rabe , Tobias S Iveland , Per Arne Aas , Animesh Sharma , Bjørnar Sporsheim , Hilde O Erlandsen , Vuk Palibrk , Magnar Bjørås , Davi M Fonseca , Nima Mosammaparast , Geir Slupphaug

Immunoaffinity Purification of Epitope-Tagged DNA Repair Complexes from Human Cells.

Methods in molecular biology (Clifton, N.J.)

Avec: Brittany A Townley , Jennifer M Soll , Nima Mosammaparast

YTHDC1 cooperates with the THO complex to prevent RNA damage-induced DNA breaks.

bioRxiv : the preprint server for biology

Avec: Ning Tsao , Jennifer Olabode , Rebecca Rodell , Hua Sun , Joshua R Brickner , Miaw-Sheue Tsai , Elizabeth A Pollina , Chun-Kan Chen , Nima Mosammaparast

ASCC1 structures and bioinformatics reveal a novel Helix-Clasp-Helix RNA-binding motif linked to a two-histidine phosphodiesterase.

The Journal of biological chemistry

Avec: Naga Babu Chinnam , Roopa Thapar , Andrew S Arvai , Altaf H Sarker , Jennifer M Soll , Tanmoy Paul , Aleem Syed , Daniel J Rosenberg , Michal Hammel , Albino Bacolla , Panagiotis Katsonis , Abhishek Asthana , Miaw-Sheue Tsai , Ivaylo Ivanov , Olivier Lichtarge , Robert H Silverman , Nima Mosammaparast , Susan E Tsutakawa , John A Tainer

The debranching enzyme Dbr1 regulates lariat turnover and intron splicing.

Nature communications

RNA Damage Responses in Cellular Homeostasis, Genome Stability, and Disease.

Annual review of pathology

Avec: Hani S Zaher , Nima Mosammaparast

Réseau de co-auteurs

Ning Tsao 10 collaborations

Alessandro Vindigni 8 collaborations

Andrea K Byrum 7 collaborations

Joshua R Brickner 6 collaborations

Brittany A Townley 6 collaborations

Rebecca Rodell 5 collaborations

Albino Bacolla 4 collaborations

Jennifer M Soll 4 collaborations

John A Tainer 4 collaborations

Clement Oyeniran 3 collaborations

Luke Buerer 3 collaborations

William G Fairbrother 3 collaborations

Hua Sun 3 collaborations

Miaw-Sheue Tsai 3 collaborations

Denisse Carvajal-Maldonado 2 collaborations

Jessica Jackson 2 collaborations

Annabel Quinet 2 collaborations

Timur Rusanov 2 collaborations

Valentina Lukinović 2 collaborations

Tanveer Ahmad 2 collaborations

Alexandre G Casanova 2 collaborations

Nicolas Reynoird 2 collaborations

Nathaniel E Clark 2 collaborations

Anastasia Welch 2 collaborations

Chaorui Duan 2 collaborations

Allison J Taggart 2 collaborations

Jing Wang 2 collaborations

Rachel Soemedi 2 collaborations

Stephen Rong 2 collaborations

Chien-Ling Lin 2 collaborations

Yi Zeng 2 collaborations

Adam Katolik 2 collaborations

Jonathan P Staley 2 collaborations

Masad J Damha 2 collaborations

Wei Yang 2 collaborations

Mohamed E Ashour 2 collaborations

Adit Ganguly 2 collaborations

Hani S Zaher 2 collaborations

Lindsay M Kuroki 2 collaborations

Carolyn K McCourt 2 collaborations

Andrea R Hagemann 2 collaborations

Premal H Thaker 2 collaborations

David G Mutch 2 collaborations

Matthew A Powell 2 collaborations

Peinan Zhao 2 collaborations

Elena Lomonosova 2 collaborations

Dineo Khabele 2 collaborations

Mary M Mullen 2 collaborations

Rachel Johnston 2 collaborations

Lynn S White 2 collaborations

Jeffrey J Bednarski 2 collaborations

Roopa Thapar 2 collaborations

Naga Babu Chinnam 2 collaborations

Barbara Blachut 2 collaborations

Sarah Wessel 1 collaboration

Delphine Lemaçon 1 collaboration

Laure Guitton-Sert 1 collaboration

Stephanie Tirman 1 collaboration

Simona Graziano 1 collaboration

Jean-Yves Masson 1 collaboration

David Cortez 1 collaboration

Susana Gonzalo 1 collaboration

Patrick M Lombardi 1 collaboration

Sara Haile 1 collaboration

Rita Anoh 1 collaboration

Julia G Baer 1 collaboration

Kate A Burke 1 collaboration

Lauren N Gray 1 collaboration

Abigail R Hacker 1 collaboration

Kayla R Kebreau 1 collaboration

Christine K Ngandu 1 collaboration

Hannah A Orland 1 collaboration

Emmanuella Osei-Asante 1 collaboration

Dhane P Schmelyun 1 collaboration

Devin E Shorb 1 collaboration

Shaheer H Syed 1 collaboration

Julianna M Veilleux 1 collaboration

Ananya Majumdar 1 collaboration

Cynthia Wolberger 1 collaboration

Simone Hausmann 1 collaboration

Gael S Roth 1 collaboration

Florent Chuffart 1 collaboration

Ana Morales Benitez 1 collaboration

Jessica Vayr 1 collaboration

Marianne Tardif 1 collaboration

Pascal W T C Jansen 1 collaboration

Yohann Couté 1 collaboration

Michiel Vermeulen 1 collaboration

Pierre Hainaut 1 collaboration

Pawel K Mazur 1 collaboration

Orlando D Schärer 1 collaboration

Tatenda Mahlokozera 1 collaboration

Bhuvic Patel 1 collaboration

Hao Chen 1 collaboration

Patrick Desouza 1 collaboration

Xuan Qu 1 collaboration

Diane D Mao 1 collaboration

Daniel Hafez 1 collaboration

Rukayat Taiwo 1 collaboration

Mounica Paturu 1 collaboration

Afshin Salehi 1 collaboration

Amit D Gujar 1 collaboration

Gavin P Dunn 1 collaboration

Allegra A Petti 1 collaboration

Hiroko Yano 1 collaboration

Albert H Kim 1 collaboration

Alice Meroni 1 collaboration

Jun Xia 1 collaboration

Saurabh Singh 1 collaboration

Roberto Galletto 1 collaboration

Susan M Rosenberg 1 collaboration

Matthew Wood 1 collaboration

Lisheng Zhang 1 collaboration

Chuan He 1 collaboration

Braulio Bonilla 1 collaboration

Alexander J Brown 1 collaboration

Sarah R Hengel 1 collaboration

Kyle S Rapchak 1 collaboration

Debra Mitchell 1 collaboration

Catherine A Pressimone 1 collaboration

Adeola A Fagunloye 1 collaboration

Thong T Luong 1 collaboration

Reagan A Russell 1 collaboration

Rudri K Vyas 1 collaboration

Tony M Mertz 1 collaboration

Ewa P Malc 1 collaboration

Piotr A Mieczkowski 1 collaboration

Steven A Roberts 1 collaboration

Kara A Bernstein 1 collaboration

Amanda J Compadre 1 collaboration

Lillian N van Biljon 1 collaboration

Mark C Valentine 1 collaboration

Alba Llop-Guevara 1 collaboration

Emily Graham 1 collaboration

Bisiayo Fashemi 1 collaboration

Andrea Herencia-Ropero 1 collaboration

Emilee N Kotnik 1 collaboration

Isaac Cooper 1 collaboration

Shariska P Harrington 1 collaboration

Lulu Sun 1 collaboration

Violeta Serra 1 collaboration

Brendan Mathias 1 collaboration

Stephanie J Crowley 1 collaboration

Haley A Schmidt 1 collaboration

Abby M Green 1 collaboration

Junqiao Jia 1 collaboration

Tarek Hilal 1 collaboration

Katherine E Bohnsack 1 collaboration

Aleksandar Chernev 1 collaboration

Juliane Bethmann 1 collaboration

Aruna Arumugam 1 collaboration

Lane Parmely 1 collaboration

Nicole Holton 1 collaboration

Bernhard Loll 1 collaboration

Markus T Bohnsack 1 collaboration

Henning Urlaub 1 collaboration

Markus C Wahl 1 collaboration

Fadhel Mansoori 1 collaboration

Nathanial Clark 1 collaboration

Negar Goodarzi 1 collaboration

Nicolas Schmidt 1 collaboration

Sridhar Nonavinkere Srivatsan 1 collaboration

Reilly A Sample 1 collaboration

Drew McDonald 1 collaboration

Matthew J Walter 1 collaboration

David F Wozniak 1 collaboration

Alex S Holehouse 1 collaboration

Vladimir Pena 1 collaboration

Lingzhen Kong 1 collaboration

Chen Cheng 1 collaboration

Abigael Cheruiyot 1 collaboration

Jiayi Yuan 1 collaboration

Yichan Yang 1 collaboration

Sydney Hwang 1 collaboration

Daniel Foust 1 collaboration

Emily Wilkerson 1 collaboration

Michael B Major 1 collaboration

David W Piston 1 collaboration

Shan Li 1 collaboration

Zhongsheng You 1 collaboration

Hongming Ma 1 collaboration

Wei Qian 1 collaboration

Monika Bambouskova 1 collaboration

Patrick L Collins 1 collaboration

Sofia I Porter 1 collaboration

Rong Zhang 1 collaboration

Maxim Artyomov 1 collaboration

Eugene M Oltz 1 collaboration

Jonathan J Miner 1 collaboration

Michael S Diamond 1 collaboration

Bo-Ruei Chen 1 collaboration

Matteo Berti 1 collaboration

Saravanabhavan Thangavel 1 collaboration

Andrea L Bredemeyer 1 collaboration

Issa Hindi 1 collaboration

Jessica K Tyler 1 collaboration

Barry P Sleckman 1 collaboration

Elsa Callen 1 collaboration

Dali Zong 1 collaboration

Wei Wu 1 collaboration

Nancy Wong 1 collaboration

Andre Stanlie 1 collaboration

Momoko Ishikawa 1 collaboration

Raphael Pavani 1 collaboration

Lavinia C Dumitrache 1 collaboration

Carlos Mendez-Dorantes 1 collaboration

Paula Martinez 1 collaboration

Andres Canela 1 collaboration

Yaakov Maman 1 collaboration

Amanda Day 1 collaboration

Michael J Kruhlak 1 collaboration

Maria A Blasco 1 collaboration

Jeremy M Stark 1 collaboration

Peter J McKinnon 1 collaboration

André Nussenzweig 1 collaboration

Deepti Soodgupta 1 collaboration

Jared M Andrews 1 collaboration

Masako Kohyama 1 collaboration

Kenneth M Murphy 1 collaboration

Jacqueline E Payton 1 collaboration

Mohamed Elsaid Ashour 1 collaboration

Miranda C Mudge 1 collaboration

David Valle-Garcia 1 collaboration

Mona C Majid 1 collaboration

Romil Patel 1 collaboration

Mathew E Sowa 1 collaboration

Steven P Gygi 1 collaboration

J Wade Harper 1 collaboration

Yang Shi 1 collaboration

Katherine Fuh 1 collaboration

Mary Mullen 1 collaboration

Elizabeth Stover 1 collaboration

Panagiotis Konstantinopoulos 1 collaboration

Joyce Liu 1 collaboration

Ursula Matulonis 1 collaboration

Michael D Toboni 1 collaboration

Alyssa Oplt 1 collaboration

Emily Cybulla 1 collaboration

Hollie Noia 1 collaboration

Daniel Wilke 1 collaboration

Erinn B Rankin 1 collaboration

Ian S Hagemann 1 collaboration

Katherine C Fuh 1 collaboration

Kristian Lied Wollen 1 collaboration

Lars Hagen 1 collaboration

Cathrine B Vågbø 1 collaboration

Renana Rabe 1 collaboration

Tobias S Iveland 1 collaboration

Per Arne Aas 1 collaboration

Animesh Sharma 1 collaboration

Bjørnar Sporsheim 1 collaboration

Hilde O Erlandsen 1 collaboration

Vuk Palibrk 1 collaboration

Magnar Bjørås 1 collaboration

Davi M Fonseca 1 collaboration

Geir Slupphaug 1 collaboration

Jennifer Olabode 1 collaboration

Elizabeth A Pollina 1 collaboration

Chun-Kan Chen 1 collaboration

Andrew S Arvai 1 collaboration

Altaf H Sarker 1 collaboration

Tanmoy Paul 1 collaboration

Aleem Syed 1 collaboration

Daniel J Rosenberg 1 collaboration

Michal Hammel 1 collaboration

Panagiotis Katsonis 1 collaboration

Abhishek Asthana 1 collaboration

Ivaylo Ivanov 1 collaboration

Olivier Lichtarge 1 collaboration

Robert H Silverman 1 collaboration

Susan E Tsutakawa 1 collaboration