Noam Auslander

Affiliations

Section of Cancer Genomics, Genetics Branch, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Cancer Data Science Laboratory, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD, USA.
Program in Molecular and Cellular Oncogenesis, The Wistar Institute, Philadelphia, PA, USA.

Publications (27)

Gene-expression profiles of pretreatment biopsies predict complete response of rectal cancer patients to preoperative chemoradiotherapy.

British journal of cancer

Avec: Georg Emons , Noam Auslander , Peter Jo , Julia Kitz , Azadeh Azizian , Yue Hu , Clemens F Hess , Claus Roedel , Ulrich Sax , Gabriela Salinas , Philipp Stroebel , Frank Kramer , Tim Beissbarth , Marian Grade , Michael Ghadimi , Eytan Ruppin , Thomas Ried , Jochen Gaedcke

Parkin activates innate immunity and promotes anti-tumor immune responses.

The Journal of clinical investigation

Avec: Michela Perego , Minjeong Yeon , Ekta Agarwal , Andrew T Milcarek , Irene Bertolini , Chiara Camisaschi , Jagadish C Ghosh , Hsin-Yao Tang , Nathalie Grandvaux , Marcus Ruscetti , Andrew V Kossenkov , Sarah Preston-Alp , Italo Tempera , Noam Auslander , Dario C Altieri

Interplay between DNA damage repair and apoptosis shapes cancer evolution through aneuploidy and microsatellite instability.

Nature communications

Avec: Noam Auslander , Yuri I Wolf , Eugene V Koonin

In silico learning of tumor evolution through mutational time series.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Noam Auslander , Yuri I Wolf , Eugene V Koonin

A unique insert in the genomes of high-risk human papillomaviruses with a predicted dual role in conferring oncogenic risk.

F1000Research

Avec: Noam Auslander , Yuri I Wolf , Svetlana A Shabalina , Eugene V Koonin

Incorporating Machine Learning into Established Bioinformatics Frameworks.

International journal of molecular sciences

Avec: Noam Auslander , Ayal B Gussow , Eugene V Koonin

Prediction of the incubation period for COVID-19 and future virus disease outbreaks.

BMC biology

Avec: Ayal B Gussow , Noam Auslander , Yuri I Wolf , Eugene V Koonin

Identification of combinations of somatic mutations that predict cancer survival and immunotherapy benefit.

NAR cancer

Avec: Ayal B Gussow , Eugene V Koonin , Noam Auslander

Computational Methods Summarizing Mutational Patterns in Cancer: Promise and Limitations for Clinical Applications.

Cancers

Avec: Andrew Patterson , Abdurrahman Elbasir , Bin Tian , Noam Auslander

An African-Specific Variant of TP53 Reveals PADI4 as a Regulator of p53-Mediated Tumor Suppression.

Cancer discovery

Avec: Alexandra Indeglia , Jessica C Leung , Sven A Miller , Julia I-Ju Leu , James F Dougherty , Nicole L Clarke , Nicole A Kirven , Chunlei Shao , Lei Ke , Scott Lovell , Thibaut Barnoud , David Y Lu , Cindy Lin , Toshitha Kannan , Kevin P Battaile , Tyler Hong Loong Yang , Isabela Batista Oliva , Daniel T Claiborne , Peter Vogel , Lijun Liu , Qin Liu , Yulia Nefedova , Joel Cassel , Noam Auslander , Andrew V Kossenkov , John Karanicolas , Maureen E Murphy

The microbiome-derived metabolite TMAO drives immune activation and boosts responses to immune checkpoint blockade in pancreatic cancer.

Science immunology

Avec: Gauri Mirji , Alison Worth , Sajad Ahmad Bhat , Mohamed El Sayed , Toshitha Kannan , Aaron R Goldman , Hsin-Yao Tang , Qin Liu , Noam Auslander , Chi V Dang , Mohamed Abdel-Mohsen , Andrew Kossenkov , Ben Z Stanger , Rahul S Shinde

Microbial gene expression analysis of healthy and cancerous esophagus uncovers bacterial biomarkers of clinical outcomes.

ISME communications

Avec: Daniel E Schäffer , Wenrui Li , Abdurrahman Elbasir , Dario C Altieri , Qi Long , Noam Auslander

Multiple sclerosis patient-derived spontaneous B cells have distinct EBV and host gene expression profiles in active disease.

Nature microbiology

Avec: Samantha S Soldan , Chenhe Su , Maria Chiara Monaco , Leena Yoon , Toshitha Kannan , Urvi Zankharia , Rishi J Patel , Jayaraju Dheekollu , Olga Vladimirova , Jack W Dowling , Simon Thebault , Natalie Brown , Annaliese Clauze , Frances Andrada , Andries Feder , Paul J Planet , Andrew Kossenkov , Daniel E Schäffer , Joan Ohayon , Noam Auslander , Steven Jacobson , Paul M Lieberman

Targeting LxCxE cleft pocket of retinoblastoma protein in M2 macrophages inhibits ovarian cancer progression.

bioRxiv : the preprint server for biology

Avec: Evgenii N Tcyganov , Taekyoung Kwak , Xue Yang , Adi Narayana Reddy Poli , Colin Hart , Avishek Bhuniya , Joel Cassel , Andrew Kossenkov , Noam Auslander , Lily Lu , Paridhima Sharma , Maria De Grecia Cauti Mendoza , Dmitry Zhigarev , Mark Gregory Cadungog , Stephanie Jean , Sudeshna Chatterjee-Paer , David Weiner , Laxminarasimha Donthireddy , Bryan Bristow , Rugang Zhang , Vladimir A Tyurin , Yulia Y Tyurina , Hülya Bayir , Valerian E Kagan , Joseph M Salvino , Luis J Montaner

Predicting Complete Remission of Acute Myeloid Leukemia: Machine Learning Applied to Gene Expression.

Cancer informatics

Avec: Ophir Gal , Noam Auslander , Yu Fan , Daoud Meerzaman

Functional Genomic Complexity Defines Intratumor Heterogeneity and Tumor Aggressiveness in Liver Cancer.

Scientific reports

Avec: So Mee Kwon , Anuradha Budhu , Hyun Goo Woo , Jittiporn Chaisaingmongkol , Hien Dang , Marshonna Forgues , Curtis C Harris , Gao Zhang , Noam Auslander , Eytan Ruppin , Chulabhorn Mahidol , Mathuros Ruchirawat , Xin Wei Wang

Single-Cell-Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Rüdiger Braun , Lena Anthuber , Daniela Hirsch , Darawalee Wangsa , Justin Lack , Nicole E McNeil , Kerstin Heselmeyer-Haddad , Irianna Torres , Danny Wangsa , Markus A Brown , Anthony Tubbs , Noam Auslander , E Michael Gertz , Philip R Brauer , Margaret C Cam , Dan L Sackett , Jens K Habermann , Andre Nussenzweig , Eytan Ruppin , Zhongqiu Zhang , Daniel W Rosenberg , Thomas Ried

Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses.

bioRxiv : the preprint server for biology

Avec: Ayal B Gussow , Noam Auslander , Guilhem Faure , Yuri I Wolf , Feng Zhang , Eugene V Koonin

Genomic determinants of pathogenicity in SARS-CoV-2 and other human coronaviruses.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Ayal B Gussow , Noam Auslander , Guilhem Faure , Yuri I Wolf , Feng Zhang , Eugene V Koonin

Unstable EBV latency drives inflammation in multiple sclerosis patient derived spontaneous B cells.

Research square

Avec: Samantha Soldan , Chenhe Su , Maria Chiara Monaco , Natalie Brown , Annaliese Clauze , Frances Andrada , Andries Feder , Paul Planet , Andrew Kossenkov , Daniel Schäffer , Joan Ohayon , Noam Auslander , Steve Jacobson , Paul Lieberman

Pyrvinium Pamoate Induces Death of Triple-Negative Breast Cancer Stem-Like Cells and Reduces Metastases through Effects on Lipid Anabolism.

Cancer research

Avec: Rosanna Dattilo , Carla Mottini , Emanuela Camera , Alessia Lamolinara , Noam Auslander , Ginevra Doglioni , Michela Muscolini , Wei Tang , Melanie Planque , Cristiana Ercolani , Simonetta Buglioni , Isabella Manni , Daniela Trisciuoglio , Alessandra Boe , Sveva Grande , Anna Maria Luciani , Manuela Iezzi , Gennaro Ciliberto , Stefan Ambs , Ruggero De Maria , Sarah-Maria Fendt , Eytan Ruppin , Luca Cardone

The GENDULF algorithm: mining transcriptomics to uncover modifier genes for monogenic diseases.

Molecular systems biology

Avec: Noam Auslander , Daniel M Ramos , Ivette Zelaya , Hiren Karathia , Thomas O Crawford , Alejandro A Schäffer , Charlotte J Sumner , Eytan Ruppin

Seeker: alignment-free identification of bacteriophage genomes by deep learning.

Nucleic acids research

Avec: Noam Auslander , Ayal B Gussow , Sean Benler , Yuri I Wolf , Eugene V Koonin

Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies.

Genome medicine

Avec: Sushant Patkar , Kerstin Heselmeyer-Haddad , Noam Auslander , Daniela Hirsch , Jordi Camps , Daniel Bronder , Markus Brown , Wei-Dong Chen , Rachel Lokanga , Darawalee Wangsa , Danny Wangsa , Yue Hu , Annette Lischka , Rüdiger Braun , Georg Emons , B Michael Ghadimi , Jochen Gaedcke , Marian Grade , Cristina Montagna , Yuri Lazebnik , Michael J Difilippantonio , Jens K Habermann , Gert Auer , Eytan Ruppin , Thomas Ried

Mutated processes predict immune checkpoint inhibitor therapy benefit in metastatic melanoma.

Nature communications

Avec: Andrew Patterson , Noam Auslander

A deep learning approach reveals unexplored landscape of viral expression in cancer.

Nature communications

Avec: Abdurrahman Elbasir , Ying Ye , Daniel E Schäffer , Xue Hao , Jayamanna Wickramasinghe , Konstantinos Tsingas , Paul M Lieberman , Qi Long , Quaid Morris , Rugang Zhang , Alejandro A Schäffer , Noam Auslander

A selective S-acyltransferase inhibitor suppresses tumor growth.

bioRxiv : the preprint server for biology

Avec: Jia-Ying Lee , Sebastian Dilones , Timothe Maujean , Mohammad Asad , Altaf Mohd , Noam Auslander , Donita C Brady , George M Burslem , Eric S Witze

Réseau de co-auteurs

Eugene V Koonin 9 collaborations

Yuri I Wolf 7 collaborations

Eytan Ruppin 6 collaborations

Ayal B Gussow 6 collaborations

Andrew Kossenkov 4 collaborations

Thomas Ried 3 collaborations

Abdurrahman Elbasir 3 collaborations

Toshitha Kannan 3 collaborations

Daniel E Schäffer 3 collaborations

Georg Emons 2 collaborations

Yue Hu 2 collaborations

Marian Grade 2 collaborations

Jochen Gaedcke 2 collaborations

Hsin-Yao Tang 2 collaborations

Andrew V Kossenkov 2 collaborations

Dario C Altieri 2 collaborations

Andrew Patterson 2 collaborations

Qin Liu 2 collaborations

Joel Cassel 2 collaborations

Qi Long 2 collaborations

Chenhe Su 2 collaborations

Maria Chiara Monaco 2 collaborations

Natalie Brown 2 collaborations

Annaliese Clauze 2 collaborations

Frances Andrada 2 collaborations

Andries Feder 2 collaborations

Joan Ohayon 2 collaborations

Paul M Lieberman 2 collaborations

Rugang Zhang 2 collaborations

Rüdiger Braun 2 collaborations

Daniela Hirsch 2 collaborations

Darawalee Wangsa 2 collaborations

Kerstin Heselmeyer-Haddad 2 collaborations

Danny Wangsa 2 collaborations

Jens K Habermann 2 collaborations

Guilhem Faure 2 collaborations

Feng Zhang 2 collaborations

Alejandro A Schäffer 2 collaborations

Peter Jo 1 collaboration

Julia Kitz 1 collaboration

Azadeh Azizian 1 collaboration

Clemens F Hess 1 collaboration

Claus Roedel 1 collaboration

Ulrich Sax 1 collaboration

Gabriela Salinas 1 collaboration

Philipp Stroebel 1 collaboration

Frank Kramer 1 collaboration

Tim Beissbarth 1 collaboration

Michael Ghadimi 1 collaboration

Michela Perego 1 collaboration

Minjeong Yeon 1 collaboration

Ekta Agarwal 1 collaboration

Andrew T Milcarek 1 collaboration

Irene Bertolini 1 collaboration

Chiara Camisaschi 1 collaboration

Jagadish C Ghosh 1 collaboration

Nathalie Grandvaux 1 collaboration

Marcus Ruscetti 1 collaboration

Sarah Preston-Alp 1 collaboration

Italo Tempera 1 collaboration

Svetlana A Shabalina 1 collaboration

Bin Tian 1 collaboration

Alexandra Indeglia 1 collaboration

Jessica C Leung 1 collaboration

Sven A Miller 1 collaboration

Julia I-Ju Leu 1 collaboration

James F Dougherty 1 collaboration

Nicole L Clarke 1 collaboration

Nicole A Kirven 1 collaboration

Chunlei Shao 1 collaboration

Lei Ke 1 collaboration

Scott Lovell 1 collaboration

Thibaut Barnoud 1 collaboration

David Y Lu 1 collaboration

Cindy Lin 1 collaboration

Kevin P Battaile 1 collaboration

Tyler Hong Loong Yang 1 collaboration

Isabela Batista Oliva 1 collaboration

Daniel T Claiborne 1 collaboration

Peter Vogel 1 collaboration

Lijun Liu 1 collaboration

Yulia Nefedova 1 collaboration

John Karanicolas 1 collaboration

Maureen E Murphy 1 collaboration

Gauri Mirji 1 collaboration

Alison Worth 1 collaboration

Sajad Ahmad Bhat 1 collaboration

Mohamed El Sayed 1 collaboration

Aaron R Goldman 1 collaboration

Chi V Dang 1 collaboration

Mohamed Abdel-Mohsen 1 collaboration

Ben Z Stanger 1 collaboration

Rahul S Shinde 1 collaboration

Wenrui Li 1 collaboration

Samantha S Soldan 1 collaboration

Leena Yoon 1 collaboration

Urvi Zankharia 1 collaboration

Rishi J Patel 1 collaboration

Jayaraju Dheekollu 1 collaboration

Olga Vladimirova 1 collaboration

Jack W Dowling 1 collaboration

Simon Thebault 1 collaboration

Paul J Planet 1 collaboration

Steven Jacobson 1 collaboration

Evgenii N Tcyganov 1 collaboration

Taekyoung Kwak 1 collaboration

Xue Yang 1 collaboration

Adi Narayana Reddy Poli 1 collaboration

Colin Hart 1 collaboration

Avishek Bhuniya 1 collaboration

Lily Lu 1 collaboration

Paridhima Sharma 1 collaboration

Maria De Grecia Cauti Mendoza 1 collaboration

Dmitry Zhigarev 1 collaboration

Mark Gregory Cadungog 1 collaboration

Stephanie Jean 1 collaboration

Sudeshna Chatterjee-Paer 1 collaboration

David Weiner 1 collaboration

Laxminarasimha Donthireddy 1 collaboration

Bryan Bristow 1 collaboration

Vladimir A Tyurin 1 collaboration

Yulia Y Tyurina 1 collaboration

Hülya Bayir 1 collaboration

Valerian E Kagan 1 collaboration

Joseph M Salvino 1 collaboration

Luis J Montaner 1 collaboration

Ophir Gal 1 collaboration

Yu Fan 1 collaboration

Daoud Meerzaman 1 collaboration

So Mee Kwon 1 collaboration

Anuradha Budhu 1 collaboration

Hyun Goo Woo 1 collaboration

Jittiporn Chaisaingmongkol 1 collaboration

Hien Dang 1 collaboration

Marshonna Forgues 1 collaboration

Curtis C Harris 1 collaboration

Gao Zhang 1 collaboration

Chulabhorn Mahidol 1 collaboration

Mathuros Ruchirawat 1 collaboration

Xin Wei Wang 1 collaboration

Lena Anthuber 1 collaboration

Justin Lack 1 collaboration

Nicole E McNeil 1 collaboration

Irianna Torres 1 collaboration

Markus A Brown 1 collaboration

Anthony Tubbs 1 collaboration

E Michael Gertz 1 collaboration

Philip R Brauer 1 collaboration

Margaret C Cam 1 collaboration

Dan L Sackett 1 collaboration

Andre Nussenzweig 1 collaboration

Zhongqiu Zhang 1 collaboration

Daniel W Rosenberg 1 collaboration

Samantha Soldan 1 collaboration

Paul Planet 1 collaboration

Daniel Schäffer 1 collaboration

Steve Jacobson 1 collaboration

Paul Lieberman 1 collaboration

Rosanna Dattilo 1 collaboration

Carla Mottini 1 collaboration

Emanuela Camera 1 collaboration

Alessia Lamolinara 1 collaboration

Ginevra Doglioni 1 collaboration

Michela Muscolini 1 collaboration

Wei Tang 1 collaboration

Melanie Planque 1 collaboration

Cristiana Ercolani 1 collaboration

Simonetta Buglioni 1 collaboration

Isabella Manni 1 collaboration

Daniela Trisciuoglio 1 collaboration

Alessandra Boe 1 collaboration

Sveva Grande 1 collaboration

Anna Maria Luciani 1 collaboration

Manuela Iezzi 1 collaboration

Gennaro Ciliberto 1 collaboration

Stefan Ambs 1 collaboration

Ruggero De Maria 1 collaboration

Sarah-Maria Fendt 1 collaboration

Luca Cardone 1 collaboration

Daniel M Ramos 1 collaboration

Ivette Zelaya 1 collaboration

Hiren Karathia 1 collaboration

Thomas O Crawford 1 collaboration

Charlotte J Sumner 1 collaboration

Sean Benler 1 collaboration

Sushant Patkar 1 collaboration

Jordi Camps 1 collaboration

Daniel Bronder 1 collaboration

Markus Brown 1 collaboration

Wei-Dong Chen 1 collaboration

Rachel Lokanga 1 collaboration

Annette Lischka 1 collaboration

B Michael Ghadimi 1 collaboration

Cristina Montagna 1 collaboration

Yuri Lazebnik 1 collaboration

Michael J Difilippantonio 1 collaboration

Gert Auer 1 collaboration

Ying Ye 1 collaboration

Xue Hao 1 collaboration

Jayamanna Wickramasinghe 1 collaboration

Konstantinos Tsingas 1 collaboration

Quaid Morris 1 collaboration

Jia-Ying Lee 1 collaboration

Sebastian Dilones 1 collaboration

Timothe Maujean 1 collaboration

Mohammad Asad 1 collaboration

Altaf Mohd 1 collaboration

Donita C Brady 1 collaboration

George M Burslem 1 collaboration

Eric S Witze 1 collaboration