Kerstin Heselmeyer-Haddad

Affiliations

Genetics Branch, Center for Cancer Research, National Cancer Institute, National Institutes of Health, Bethesda, MD.

Publications (13)

Single-cell genetic analysis of clonal dynamics in colorectal adenomas indicates CDX2 gain as a predictor of recurrence.

International journal of cancer

Avec: David Fiedler , Kerstin Heselmeyer-Haddad , Daniela Hirsch , Leanora S Hernandez , Irianna Torres , Darawalee Wangsa , Yue Hu , Luis Zapata , Josef Rueschoff , Sebastian Belle , Thomas Ried , Timo Gaiser

Single Cell Genetic Profiling of Tumors of Breast Cancer Patients Aged 50 Years and Older Reveals Enormous Intratumor Heterogeneity Independent of Individual Prognosis.

Cancers

Avec: Anna-Sophie Liegmann , Kerstin Heselmeyer-Haddad , Annette Lischka , Daniela Hirsch , Wei-Dong Chen , Irianna Torres , Timo Gemoll , Achim Rody , Christoph Thorns , Edward Michael Gertz , Hendrik Alkemade , Yue Hu , Jens K Habermann , Thomas Ried

Genome Instability Profiles Predict Disease Outcome in a Cohort of 4,003 Patients with Breast Cancer.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Annette Lischka , Natalie Doberstein , Sandra Freitag-Wolf , Ayla Koçak , Timo Gemoll , Kerstin Heselmeyer-Haddad , Thomas Ried , Gert Auer , Jens K Habermann

Tumor heterogeneity assessed by sequencing and fluorescence in situ hybridization (FISH) data.

Bioinformatics (Oxford, England)

Avec: Haoyun Lei , E Michael Gertz , Alejandro A Schäffer , Xuecong Fu , Yifeng Tao , Kerstin Heselmeyer-Haddad , Irianna Torres , Guibo Li , Liqin Xu , Yong Hou , Kui Wu , Xulian Shi , Michael Dean , Thomas Ried , Russell Schwartz

Hard wiring of normal tissue-specific chromosome-wide gene expression levels is an additional factor driving cancer type-specific aneuploidies.

Genome medicine

Avec: Sushant Patkar , Kerstin Heselmeyer-Haddad , Noam Auslander , Daniela Hirsch , Jordi Camps , Daniel Bronder , Markus Brown , Wei-Dong Chen , Rachel Lokanga , Darawalee Wangsa , Danny Wangsa , Yue Hu , Annette Lischka , Rüdiger Braun , Georg Emons , B Michael Ghadimi , Jochen Gaedcke , Marian Grade , Cristina Montagna , Yuri Lazebnik , Michael J Difilippantonio , Jens K Habermann , Gert Auer , Eytan Ruppin , Thomas Ried

TP53 loss initiates chromosomal instability in fallopian tube epithelial cells.

Disease models & mechanisms

Avec: Daniel Bronder , Anthony Tighe , Darawalee Wangsa , Dali Zong , Thomas J Meyer , René Wardenaar , Paul Minshall , Daniela Hirsch , Kerstin Heselmeyer-Haddad , Louisa Nelson , Diana Spierings , Joanne C McGrail , Maggie Cam , André Nussenzweig , Floris Foijer , Thomas Ried , Stephen S Taylor

Genomic and evolutionary classification of lung cancer in never smokers.

Nature genetics

Avec: Tongwu Zhang , Philippe Joubert , Naser Ansari-Pour , Wei Zhao , Phuc H Hoang , Rachel Lokanga , Aaron L Moye , Jennifer Rosenbaum , Abel Gonzalez-Perez , Francisco Martínez-Jiménez , Andrea Castro , Lucia Anna Muscarella , Paul Hofman , Dario Consonni , Angela C Pesatori , Michael Kebede , Mengying Li , Bonnie E Gould Rothberg , Iliana Peneva , Matthew B Schabath , Maria Luana Poeta , Manuela Costantini , Daniela Hirsch , Kerstin Heselmeyer-Haddad , Amy Hutchinson , Mary Olanich , Scott M Lawrence , Petra Lenz , Maire Duggan , Praphulla M S Bhawsar , Jian Sang , Jung Kim , Laura Mendoza , Natalie Saini , Leszek J Klimczak , S M Ashiqul Islam , Burcak Otlu , Azhar Khandekar , Nathan Cole , Douglas R Stewart , Jiyeon Choi , Kevin M Brown , Neil E Caporaso , Samuel H Wilson , Yves Pommier , Qing Lan , Nathaniel Rothman , Jonas S Almeida , Hannah Carter , Thomas Ried , Carla F Kim , Nuria Lopez-Bigas , Montserrat Garcia-Closas , Jianxin Shi , Yohan Bossé , Bin Zhu , Dmitry A Gordenin , Ludmil B Alexandrov , Stephen J Chanock , David C Wedge , Maria Teresa Landi

Extrachromosomal Amplification of Human Papillomavirus Episomes Is a Mechanism of Cervical Carcinogenesis.

Cancer research

Avec: Nicole M Rossi , Jieqiong Dai , Yi Xie , Darawalee Wangsa , Kerstin Heselmeyer-Haddad , Hong Lou , Joseph F Boland , Meredith Yeager , Roberto Orozco , Enrique Alvirez Freites , Lisa Mirabello , Eduardo Gharzouzi , Michael Dean

Single-cell resolved ploidy and chromosomal aberrations in nonalcoholic steatohepatitis-(NASH) induced hepatocellular carcinoma and its precursor lesions.

Scientific reports

Avec: Juliane Friemel , Irianna Torres , Elizabeth Brauneis , Tim Thörner , Alejandro A Schäffer , E Michael Gertz , Tobias Grob , Kati Seidl , Achim Weber , Thomas Ried , Kerstin Heselmeyer-Haddad

Single Chromosome Aneuploidy Induces Genome-Wide Perturbation of Nuclear Organization and Gene Expression.

Neoplasia (New York, N.Y.)

Avec: Rüdiger Braun , Scott Ronquist , Darawalee Wangsa , Haiming Chen , Lena Anthuber , Timo Gemoll , Danny Wangsa , Vishal Koparde , Cynthia Hunn , Jens K Habermann , Kerstin Heselmeyer-Haddad , Indika Rajapakse , Thomas Ried

Single-Cell-Derived Primary Rectal Carcinoma Cell Lines Reflect Intratumor Heterogeneity Associated with Treatment Response.

Clinical cancer research : an official journal of the American Association for Cancer Research

Avec: Rüdiger Braun , Lena Anthuber , Daniela Hirsch , Darawalee Wangsa , Justin Lack , Nicole E McNeil , Kerstin Heselmeyer-Haddad , Irianna Torres , Danny Wangsa , Markus A Brown , Anthony Tubbs , Noam Auslander , E Michael Gertz , Philip R Brauer , Margaret C Cam , Dan L Sackett , Jens K Habermann , Andre Nussenzweig , Eytan Ruppin , Zhongqiu Zhang , Daniel W Rosenberg , Thomas Ried

High Levels of Chromosomal Copy Number Alterations and TP53 Mutations Correlate with Poor Outcome in Younger Breast Cancer Patients.

The American journal of pathology

Avec: Ayla Koçak , Kerstin Heselmeyer-Haddad , Annette Lischka , Daniela Hirsch , David Fiedler , Yue Hu , Natalie Doberstein , Irianna Torres , Wei-Dong Chen , E Michael Gertz , Alejandro A Schäffer , Sandra Freitag-Wolf , Jutta Kirfel , Gert Auer , Jens K Habermann , Thomas Ried

Joint Clustering of Single-Cell Sequencing and Fluorescence In Situ Hybridization Data for Reconstructing Clonal Heterogeneity in Cancers.

Journal of computational biology : a journal of computational molecular cell biology

Avec: Xuecong Fu , Haoyun Lei , Yifeng Tao , Kerstin Heselmeyer-Haddad , Irianna Torres , Michael Dean , Thomas Ried , Russell Schwartz

Réseau de co-auteurs

Thomas Ried 12 collaborations

Daniela Hirsch 7 collaborations

Irianna Torres 7 collaborations

Darawalee Wangsa 6 collaborations

Jens K Habermann 6 collaborations

Yue Hu 4 collaborations

Annette Lischka 4 collaborations

E Michael Gertz 4 collaborations

Wei-Dong Chen 3 collaborations

Timo Gemoll 3 collaborations

Gert Auer 3 collaborations

Alejandro A Schäffer 3 collaborations

Michael Dean 3 collaborations

Danny Wangsa 3 collaborations

Rüdiger Braun 3 collaborations

David Fiedler 2 collaborations

Natalie Doberstein 2 collaborations

Sandra Freitag-Wolf 2 collaborations

Ayla Koçak 2 collaborations

Haoyun Lei 2 collaborations

Xuecong Fu 2 collaborations

Yifeng Tao 2 collaborations

Russell Schwartz 2 collaborations

Noam Auslander 2 collaborations

Daniel Bronder 2 collaborations

Rachel Lokanga 2 collaborations

Eytan Ruppin 2 collaborations

Lena Anthuber 2 collaborations

Leanora S Hernandez 1 collaboration

Luis Zapata 1 collaboration

Josef Rueschoff 1 collaboration

Sebastian Belle 1 collaboration

Timo Gaiser 1 collaboration

Anna-Sophie Liegmann 1 collaboration

Achim Rody 1 collaboration

Christoph Thorns 1 collaboration

Edward Michael Gertz 1 collaboration

Hendrik Alkemade 1 collaboration

Guibo Li 1 collaboration

Liqin Xu 1 collaboration

Yong Hou 1 collaboration

Kui Wu 1 collaboration

Xulian Shi 1 collaboration

Sushant Patkar 1 collaboration

Jordi Camps 1 collaboration

Markus Brown 1 collaboration

Georg Emons 1 collaboration

B Michael Ghadimi 1 collaboration

Jochen Gaedcke 1 collaboration

Marian Grade 1 collaboration

Cristina Montagna 1 collaboration

Yuri Lazebnik 1 collaboration

Michael J Difilippantonio 1 collaboration

Anthony Tighe 1 collaboration

Dali Zong 1 collaboration

Thomas J Meyer 1 collaboration

René Wardenaar 1 collaboration

Paul Minshall 1 collaboration

Louisa Nelson 1 collaboration

Diana Spierings 1 collaboration

Joanne C McGrail 1 collaboration

Maggie Cam 1 collaboration

André Nussenzweig 1 collaboration

Floris Foijer 1 collaboration

Stephen S Taylor 1 collaboration

Tongwu Zhang 1 collaboration

Philippe Joubert 1 collaboration

Naser Ansari-Pour 1 collaboration

Wei Zhao 1 collaboration

Phuc H Hoang 1 collaboration

Aaron L Moye 1 collaboration

Jennifer Rosenbaum 1 collaboration

Abel Gonzalez-Perez 1 collaboration

Francisco Martínez-Jiménez 1 collaboration

Andrea Castro 1 collaboration

Lucia Anna Muscarella 1 collaboration

Paul Hofman 1 collaboration

Dario Consonni 1 collaboration

Angela C Pesatori 1 collaboration

Michael Kebede 1 collaboration

Mengying Li 1 collaboration

Bonnie E Gould Rothberg 1 collaboration

Iliana Peneva 1 collaboration

Matthew B Schabath 1 collaboration

Maria Luana Poeta 1 collaboration

Manuela Costantini 1 collaboration

Amy Hutchinson 1 collaboration

Mary Olanich 1 collaboration

Scott M Lawrence 1 collaboration

Petra Lenz 1 collaboration

Maire Duggan 1 collaboration

Praphulla M S Bhawsar 1 collaboration

Jian Sang 1 collaboration

Jung Kim 1 collaboration

Laura Mendoza 1 collaboration

Natalie Saini 1 collaboration

Leszek J Klimczak 1 collaboration

S M Ashiqul Islam 1 collaboration

Burcak Otlu 1 collaboration

Azhar Khandekar 1 collaboration

Nathan Cole 1 collaboration

Douglas R Stewart 1 collaboration

Jiyeon Choi 1 collaboration

Kevin M Brown 1 collaboration

Neil E Caporaso 1 collaboration

Samuel H Wilson 1 collaboration

Yves Pommier 1 collaboration

Qing Lan 1 collaboration

Nathaniel Rothman 1 collaboration

Jonas S Almeida 1 collaboration

Hannah Carter 1 collaboration

Carla F Kim 1 collaboration

Nuria Lopez-Bigas 1 collaboration

Montserrat Garcia-Closas 1 collaboration

Jianxin Shi 1 collaboration

Yohan Bossé 1 collaboration

Bin Zhu 1 collaboration

Dmitry A Gordenin 1 collaboration

Ludmil B Alexandrov 1 collaboration

Stephen J Chanock 1 collaboration

David C Wedge 1 collaboration

Maria Teresa Landi 1 collaboration

Nicole M Rossi 1 collaboration

Jieqiong Dai 1 collaboration

Yi Xie 1 collaboration

Hong Lou 1 collaboration

Joseph F Boland 1 collaboration

Meredith Yeager 1 collaboration

Roberto Orozco 1 collaboration

Enrique Alvirez Freites 1 collaboration

Lisa Mirabello 1 collaboration

Eduardo Gharzouzi 1 collaboration

Juliane Friemel 1 collaboration

Elizabeth Brauneis 1 collaboration

Tim Thörner 1 collaboration

Tobias Grob 1 collaboration

Kati Seidl 1 collaboration

Achim Weber 1 collaboration

Scott Ronquist 1 collaboration

Haiming Chen 1 collaboration

Vishal Koparde 1 collaboration

Cynthia Hunn 1 collaboration

Indika Rajapakse 1 collaboration

Justin Lack 1 collaboration

Nicole E McNeil 1 collaboration

Markus A Brown 1 collaboration

Anthony Tubbs 1 collaboration

Philip R Brauer 1 collaboration

Margaret C Cam 1 collaboration

Dan L Sackett 1 collaboration

Andre Nussenzweig 1 collaboration

Zhongqiu Zhang 1 collaboration

Daniel W Rosenberg 1 collaboration

Jutta Kirfel 1 collaboration