Patrick Midoux

Affiliations

Centre de Biophysique Moléculaire, CNRS UPR4301, Orléans, France.

Publications (22)

Neutral Block Copolymer Assisted Gene delivery using Hydrodynamic Limb Vein Injection.

Macromolecular bioscience

Avec: Yann Le Guen , Gwendoline Delecourt , Tony Le Gall , Haiqin Du , Nicolas Illy , Cécile Huin , Véronique Bennevault , Patrick Midoux , Tristan Montier , Philippe Guégan

Co-delivery of NS1 and BMP2 mRNAs to murine pluripotent stem cells leads to enhanced BMP-2 expression and osteogenic differentiation.

Acta biomaterialia

Avec: Pinpin Wang , Delphine Logeart-Avramoglou , Hervé Petite , Cristine Goncalves , Patrick Midoux , Federico Perche , Chantal Pichon

Comparative binding and uptake of liposomes decorated with mannose oligosaccharides by cells expressing the mannose receptor or DC-SIGN.

Carbohydrate research

Avec: Haifei Gao , Cristine Gonçalves , Téo Gallego , Marc François-Heude , Virginie Malard , Véronique Mateo , François Lemoine , Virginie Cendret , Florence Djedaini-Pilard , Vincent Moreau , Chantal Pichon , Patrick Midoux

Improved histidinylated lPEI polyplexes for skeletal muscle cells transfection.

International journal of pharmaceutics

Avec: Jean-Pierre Gomez , Guillaume Tresset , Chantal Pichon , Patrick Midoux

Periodic Mesoporous Organosilica Nanoparticles with BOC Group, towards HIFU Responsive Agents.

Molecules (Basel, Switzerland)

Avec: Hao Li , Carolina Gascó , Anthony Delalande , Clarence Charnay , Laurence Raehm , Patrick Midoux , Chantal Pichon , Roser Pleixats , Jean-Olivier Durand

Intracellular Routing and Recognition of Lipid-Based mRNA Nanoparticles.

Pharmaceutics

Avec: Christophe Delehedde , Luc Even , Patrick Midoux , Chantal Pichon , Federico Perche

CFTR and dystrophin encoding plasmids carrying both luciferase reporter gene, nuclear import specific sequences and triple helix sites.

Plasmid

Avec: Delphine Maze , Caroline Girardin , Nathalie Benz , Tristan Montier , Chantal Pichon , Patrick Midoux

In Vivo bone tissue induction by freeze-dried collagen-nanohydroxyapatite matrix loaded with BMP2/NS1 mRNAs lipopolyplexes.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Pinpin Wang , Federico Perche , Patrick Midoux , Cátia S D Cabral , Virginie Malard , Ilídio J Correia , Hanane Ei-Hafci , Hervé Petite , Delphine Logeart-Avramoglou , Chantal Pichon

Temperature-Sensitive Amphiphilic Non-Ionic Triblock Copolymers for Enhanced In Vivo Skeletal Muscle Transfection.

Macromolecular bioscience

Avec: Bazoly Rasolonjatovo , Nicolas Illy , Véronique Bennevault , Jérôme Mathé , Patrick Midoux , Tony Le Gall , Thomas Haudebourg , Tristan Montier , Pierre Lehn , Bruno Pitard , Herve Cheradame , Cécile Huin , Philippe Guégan

DNA minicircles as novel STAT3 decoy oligodeoxynucleotides endowed with anticancer activity in triple-negative breast cancer.

Molecular therapy. Nucleic acids

Avec: Geoffrey Casas , Federico Perche , Patrick Midoux , Chantal Pichon , Jean-Marc Malinge

Synthesis of Double Hydrophilic Block Copolymers Poly(2-isopropyl-2-oxazoline-b-ethylenimine) and their DNA Transfection Efficiency.

Macromolecular bioscience

Avec: Gwendoline Delecourt , Laetitia Plet , Yann Le Guen , Ozgul Tezgel , Guillaume Tresset , Patrick Midoux , Tristan Montier , Véronique Bennevault , Philippe Guégan

Reversible stabilization of DNA/PEI complexes by reducible click-linkage between DNA and polymer. A new polyplex concept for lowering polymer quantity.

Gene therapy

Avec: Delphine Maze , Chantal Pichon , Patrick Midoux

Gene transfer to skeletal muscle using hydrodynamic limb vein injection: current applications, hurdles and possible optimizations.

The journal of gene medicine

Avec: Yann Thierry Le Guen , Tony Le Gall , Patrick Midoux , Philippe Guégan , Serge Braun , Tristan Montier

DNA nuclear targeting sequences for enhanced non-viral gene transfer: An

Molecular therapy. Nucleic acids

Avec: Yann T Le Guen , Chantal Pichon , Philippe Guégan , Kévin Pluchon , Tanguy Haute , Sandrine Quemener , Juliette Ropars , Patrick Midoux , Tony Le Gall , Tristan Montier

Amino-acid functionalized porous silicon nanoparticles for the delivery of pDNA.

RSC advances

Avec: Arnaud Chaix , Eduardo Cueto-Diaz , Anthony Delalande , Nikola Knezevic , Patrick Midoux , Jean-Olivier Durand , Chantal Pichon , Frederique Cunin

mRNA Lipoplexes with Cationic and Ionizable α-Amino-lipophosphonates: Membrane Fusion, Transfection, mRNA Translation and Conformation.

Pharmaceutics

Avec: Sohail Akhter , Mathieu Berchel , Paul-Alain Jaffrès , Patrick Midoux , Chantal Pichon

Impact of net charge, targeting ligand amount and mRNA modification on the uptake, intracellular routing and the transfection efficiency of mRNA lipopolyplexes in dendritic cells.

International journal of pharmaceutics

Avec: Christophe Delehedde , Ivan Ciganek , Nathalie Rameix , Nabila Laroui , Cristine Gonçalves , Luc Even , Patrick Midoux , Chantal Pichon

Enhancing natural killer cells proliferation and cytotoxicity using imidazole-based lipid nanoparticles encapsulating interleukin-2 mRNA.

Molecular therapy. Nucleic acids

Avec: Christophe Delehedde , Ivan Ciganek , Pierre Louis Bernard , Nabila Laroui , Cathy Costa Da Silva , Cristine Gonçalves , Jacques Nunes , Anne-Lise Bennaceur-Griscelli , Jusuf Imeri , Matthias Huyghe , Luc Even , Patrick Midoux , Nathalie Rameix , Geoffrey Guittard , Chantal Pichon

Intracellular trafficking and functional monitoring of miRNA delivery in glioblastoma using lipopolyplexes and the miRNA-ON RILES reporter system.

Journal of controlled release : official journal of the Controlled Release Society

Avec: Viorel Simion , Elodie Henriet , Viktorija Juric , Ruth Aquino , Claire Loussouarn , Yoan Laurent , Francisco Martin , Patrick Midoux , Emmanuel Garcion , Chantal Pichon , Patrick Baril

LentiRILES, a miRNA-ON sensor system for monitoring the functionality of miRNA in cancer biology and therapy.

RNA biology

Avec: Viorel Simion , Claire Loussouarn , Yoan Laurent , Loris Roncali , David Gosset , Flora Reverchon , Audrey Rousseau , Francisco Martin , Patrick Midoux , Chantal Pichon , Emmanuel Garcion , Patrick Baril

CEBA: A new heterobifunctional reagent for plasmid DNA functionalization by click chemistry.

International journal of pharmaceutics

Avec: Haifei Gao , Cristine Gonçalves , Delphine Maze , Chantal Pichon , Patrick Midoux

Selective attachment of a microtubule interacting peptide to plasmid DNA via a triplex forming oligonucleotide for transfection improvement.

Gene therapy

Avec: Caroline Girardin , Delphine Maze , Cristine Gonçalves , Yann Thierry Le Guen , Kevin Pluchon , Chantal Pichon , Tristan Montier , Patrick Midoux

Réseau de co-auteurs

Chantal Pichon 18 collaborations

Tristan Montier 7 collaborations

Philippe Guégan 5 collaborations

Cristine Gonçalves 5 collaborations

Tony Le Gall 4 collaborations

Federico Perche 4 collaborations

Delphine Maze 4 collaborations

Véronique Bennevault 3 collaborations

Christophe Delehedde 3 collaborations

Luc Even 3 collaborations

Yann Le Guen 2 collaborations

Gwendoline Delecourt 2 collaborations

Nicolas Illy 2 collaborations

Cécile Huin 2 collaborations

Pinpin Wang 2 collaborations

Delphine Logeart-Avramoglou 2 collaborations

Hervé Petite 2 collaborations

Haifei Gao 2 collaborations

Virginie Malard 2 collaborations

Guillaume Tresset 2 collaborations

Anthony Delalande 2 collaborations

Jean-Olivier Durand 2 collaborations

Caroline Girardin 2 collaborations

Yann Thierry Le Guen 2 collaborations

Ivan Ciganek 2 collaborations

Nathalie Rameix 2 collaborations

Nabila Laroui 2 collaborations

Viorel Simion 2 collaborations

Claire Loussouarn 2 collaborations

Yoan Laurent 2 collaborations

Francisco Martin 2 collaborations

Emmanuel Garcion 2 collaborations

Patrick Baril 2 collaborations

Haiqin Du 1 collaboration

Cristine Goncalves 1 collaboration

Téo Gallego 1 collaboration

Marc François-Heude 1 collaboration

Véronique Mateo 1 collaboration

François Lemoine 1 collaboration

Virginie Cendret 1 collaboration

Florence Djedaini-Pilard 1 collaboration

Vincent Moreau 1 collaboration

Jean-Pierre Gomez 1 collaboration

Hao Li 1 collaboration

Carolina Gascó 1 collaboration

Clarence Charnay 1 collaboration

Laurence Raehm 1 collaboration

Roser Pleixats 1 collaboration

Nathalie Benz 1 collaboration

Cátia S D Cabral 1 collaboration

Ilídio J Correia 1 collaboration

Hanane Ei-Hafci 1 collaboration

Bazoly Rasolonjatovo 1 collaboration

Jérôme Mathé 1 collaboration

Thomas Haudebourg 1 collaboration

Pierre Lehn 1 collaboration

Bruno Pitard 1 collaboration

Herve Cheradame 1 collaboration

Geoffrey Casas 1 collaboration

Jean-Marc Malinge 1 collaboration

Laetitia Plet 1 collaboration

Ozgul Tezgel 1 collaboration

Serge Braun 1 collaboration

Yann T Le Guen 1 collaboration

Kévin Pluchon 1 collaboration

Tanguy Haute 1 collaboration

Sandrine Quemener 1 collaboration

Juliette Ropars 1 collaboration

Arnaud Chaix 1 collaboration

Eduardo Cueto-Diaz 1 collaboration

Nikola Knezevic 1 collaboration

Frederique Cunin 1 collaboration

Sohail Akhter 1 collaboration

Mathieu Berchel 1 collaboration

Paul-Alain Jaffrès 1 collaboration

Pierre Louis Bernard 1 collaboration

Cathy Costa Da Silva 1 collaboration

Jacques Nunes 1 collaboration

Anne-Lise Bennaceur-Griscelli 1 collaboration

Jusuf Imeri 1 collaboration

Matthias Huyghe 1 collaboration

Geoffrey Guittard 1 collaboration

Elodie Henriet 1 collaboration

Viktorija Juric 1 collaboration

Ruth Aquino 1 collaboration

Loris Roncali 1 collaboration

David Gosset 1 collaboration

Flora Reverchon 1 collaboration

Audrey Rousseau 1 collaboration

Kevin Pluchon 1 collaboration