Patrick Seale

Affiliations

Institute for Diabetes, Obesity & Metabolism, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA; Department of Cell and Developmental Biology, Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA 19104, USA. Electronic address: sealep@pennmedicine.upenn.edu.

Publications (8)

Skinny Fat Cells Stimulate Wound Healing.

Cell stem cell

Avec: David Merrick , Patrick Seale

Single-cell atlas of human infrapatellar fat pad and synovium implicates APOE signaling in osteoarthritis pathology.

Science translational medicine

Avec: Su'an Tang , Lutian Yao , Jianzhao Ruan , Jingliang Kang , Yumei Cao , Xiaoyu Nie , Weiren Lan , Zhaohua Zhu , Weiyu Han , Yongguang Liu , Jing Tian , Patrick Seale , Ling Qin , Changhai Ding

A PRDM16-Driven Metabolic Signal from Adipocytes Regulates Precursor Cell Fate.

Cell metabolism

Avec: Wenshan Wang , Jeff Ishibashi , Sophie Trefely , Mengle Shao , Alexis J Cowan , Alexander Sakers , Hee-Woong Lim , Sean O'Connor , Mary T Doan , Paul Cohen , Joseph A Baur , M Todd King , Richard L Veech , Kyoung-Jae Won , Joshua D Rabinowitz , Nathaniel W Snyder , Rana K Gupta , Patrick Seale

PRDM16 Maintains Homeostasis of the Intestinal Epithelium by Controlling Region-Specific Metabolism.

Cell stem cell

Avec: Rachel R Stine , Alexander P Sakers , Tara TeSlaa , Megan Kissig , Zachary E Stine , Chan Wook Kwon , Lan Cheng , Hee-Woong Lim , Klaus H Kaestner , Joshua D Rabinowitz , Patrick Seale

ZFP423 controls EBF2 coactivator recruitment and PPARγ occupancy to determine the thermogenic plasticity of adipocytes.

Genes & development

Avec: Mengle Shao , Qianbin Zhang , Ashley Truong , Bo Shan , Lavanya Vishvanath , Lin Li , Patrick Seale , Rana K Gupta

Defining the lineage of thermogenic perivascular adipose tissue.

Nature metabolism

Avec: Anthony R Angueira , Alexander P Sakers , Corey D Holman , Lan Cheng , Michelangella N Arbocco , Farnaz Shamsi , Matthew D Lynes , Rojesh Shrestha , Chihiro Okada , Kirill Batmanov , Katalin Susztak , Yu-Hua Tseng , Lucy Liaw , Patrick Seale

Hepatic AKT orchestrates adipose tissue thermogenesis via FGF21-dependent and -independent mechanisms.

Cell reports

Avec: Jaimarie Sostre-Colón , Kahealani Uehara , Anna E Garcia Whitlock , Matthew J Gavin , Jeff Ishibashi , Matthew J Potthoff , Patrick Seale , Paul M Titchenell

Neonatal IL-4 exposure decreases adipogenesis of male rats into adulthood.

American journal of physiology. Endocrinology and metabolism

Avec: Tammy Ying , Thea Golden , Lan Cheng , Jeff Ishibashi , Patrick Seale , Rebecca A Simmons

Réseau de co-auteurs

Jeff Ishibashi 3 collaborations

Lan Cheng 3 collaborations

Mengle Shao 2 collaborations

Hee-Woong Lim 2 collaborations

Joshua D Rabinowitz 2 collaborations

Rana K Gupta 2 collaborations

Alexander P Sakers 2 collaborations

David Merrick 1 collaboration

Su'an Tang 1 collaboration

Lutian Yao 1 collaboration

Jianzhao Ruan 1 collaboration

Jingliang Kang 1 collaboration

Yumei Cao 1 collaboration

Xiaoyu Nie 1 collaboration

Weiren Lan 1 collaboration

Zhaohua Zhu 1 collaboration

Weiyu Han 1 collaboration

Yongguang Liu 1 collaboration

Jing Tian 1 collaboration

Ling Qin 1 collaboration

Changhai Ding 1 collaboration

Wenshan Wang 1 collaboration

Sophie Trefely 1 collaboration

Alexis J Cowan 1 collaboration

Alexander Sakers 1 collaboration

Sean O'Connor 1 collaboration

Mary T Doan 1 collaboration

Paul Cohen 1 collaboration

Joseph A Baur 1 collaboration

M Todd King 1 collaboration

Richard L Veech 1 collaboration

Kyoung-Jae Won 1 collaboration

Nathaniel W Snyder 1 collaboration

Rachel R Stine 1 collaboration

Tara TeSlaa 1 collaboration

Megan Kissig 1 collaboration

Zachary E Stine 1 collaboration

Chan Wook Kwon 1 collaboration

Klaus H Kaestner 1 collaboration

Qianbin Zhang 1 collaboration

Ashley Truong 1 collaboration

Bo Shan 1 collaboration

Lavanya Vishvanath 1 collaboration

Lin Li 1 collaboration

Anthony R Angueira 1 collaboration

Corey D Holman 1 collaboration

Michelangella N Arbocco 1 collaboration

Farnaz Shamsi 1 collaboration

Matthew D Lynes 1 collaboration

Rojesh Shrestha 1 collaboration

Chihiro Okada 1 collaboration

Kirill Batmanov 1 collaboration

Katalin Susztak 1 collaboration

Yu-Hua Tseng 1 collaboration

Lucy Liaw 1 collaboration

Jaimarie Sostre-Colón 1 collaboration

Kahealani Uehara 1 collaboration

Anna E Garcia Whitlock 1 collaboration

Matthew J Gavin 1 collaboration

Matthew J Potthoff 1 collaboration

Paul M Titchenell 1 collaboration

Tammy Ying 1 collaboration

Thea Golden 1 collaboration

Rebecca A Simmons 1 collaboration