Paul B McCray

Affiliations

Stead Family Department of Pediatrics.
Pappajohn Biomedical Institute.
Center for Gene Therapy, and.

Publications (24)

A Novel AAV-mediated Gene Delivery System Corrects CFTR Function in Pigs.

American journal of respiratory cell and molecular biology

Avec: Ashley L Cooney , Ian M Thornell , Brajesh K Singh , Viral S Shah , David A Stoltz , Paul B McCray , Joseph Zabner , Patrick L Sinn

IFN-I response timing relative to virus replication determines MERS coronavirus infection outcomes.

The Journal of clinical investigation

Avec: Rudragouda Channappanavar , Anthony R Fehr , Jian Zheng , Christine Wohlford-Lenane , Juan E Abrahante , Matthias Mack , Ramakrishna Sompallae , Paul B McCray , David K Meyerholz , Stanley Perlman

Engineered amphiphilic peptides enable delivery of proteins and CRISPR-associated nucleases to airway epithelia.

Nature communications

Avec: Sateesh Krishnamurthy , Christine Wohlford-Lenane , Suhas Kandimalla , Gilles Sartre , David K Meyerholz , Vanessa Théberge , Stéphanie Hallée , Anne-Marie Duperré , Thomas Del'Guidice , Jean-Pascal Lepetit-Stoffaes , Xavier Barbeau , David Guay , Paul B McCray

The NIH Somatic Cell Genome Editing program.

Nature

Avec: Krishanu Saha , Erik J Sontheimer , P J Brooks , Melinda R Dwinell , Charles A Gersbach , David R Liu , Stephen A Murray , Shengdar Q Tsai , Ross C Wilson , Daniel G Anderson , Aravind Asokan , Jillian F Banfield , Krystof S Bankiewicz , Gang Bao , Jeff W M Bulte , Nenad Bursac , Jarryd M Campbell , Daniel F Carlson , Elliot L Chaikof , Zheng-Yi Chen , R Holland Cheng , Karl J Clark , David T Curiel , James E Dahlman , Benjamin E Deverman , Mary E Dickinson , Jennifer A Doudna , Stephen C Ekker , Marina E Emborg , Guoping Feng , Benjamin S Freedman , David M Gamm , Guangping Gao , Ionita C Ghiran , Peter M Glazer , Shaoqin Gong , Jason D Heaney , Jon D Hennebold , John T Hinson , Anastasia Khvorova , Samira Kiani , William R Lagor , Kit S Lam , Kam W Leong , Jon E Levine , Jennifer A Lewis , Cathleen M Lutz , Danith H Ly , Samantha Maragh , Paul B McCray , Todd C McDevitt , Oleg Mirochnitchenko , Ryuji Morizane , Niren Murthy , Randall S Prather , John A Ronald , Subhojit Roy , Sushmita Roy , Venkata Sabbisetti , W Mark Saltzman , Philip J Santangelo , David J Segal , Mary Shimoyama , Melissa C Skala , Alice F Tarantal , John C Tilton , George A Truskey , Moriel Vandsburger , Jonathan K Watts , Kevin D Wells , Scot A Wolfe , Qiaobing Xu , Wen Xue , Guohua Yi , Jiangbing Zhou , Auteur inconnu

Increased CFTR expression and function from an optimized lentiviral vector for cystic fibrosis gene therapy.

Molecular therapy. Methods & clinical development

Avec: Laura I Marquez Loza , Ashley L Cooney , Qian Dong , Christoph O Randak , Stefano Rivella , Patrick L Sinn , Paul B McCray

Sensitization of Non-permissive Laboratory Mice to SARS-CoV-2 with a Replication-Deficient Adenovirus Expressing Human ACE2.

STAR protocols

Avec: Lok-Yin Roy Wong , Kun Li , Jing Sun , Zhen Zhuang , Jincun Zhao , Paul B McCray , Stanley Perlman

Avian influenza A viruses exhibit plasticity in sialylglycoconjugate receptor usage in human lung cells.

Journal of virology

Avec: Chieh-Yu Liang , Iris Huang , Julianna Han , Boopathi Sownthirarajan , Katarina Kulhankova , Nathan B Murray , Mehrnoush Taherzadeh , Stephanie Archer-Hartmann , Lauren Pepi , Senthamizharasi Manivasagam , Jesse Plung , Miranda Sturtz , Yolanda Yu , Olivia A Vogel , Matheswaran Kandasamy , Francoise A Gourronc , Aloysius J Klingelhutz , Biswa Choudhury , Lijun Rong , Jasmine T Perez , Parastoo Azadi , Paul B McCray , Sriram Neelamegham , Balaji Manicassamy

Adaptation of SARS-CoV-2 to ACE2

Journal of virology

Avec: Kun Li , Abhishek Verma , Pengfei Li , Miguel E Ortiz , Grant M Hawkins , Nicholas J Schnicker , Peter J Szachowicz , Alejandro Pezullo , Christine L Wohlford-Lenane , Tom Kicmal , David K Meyerholz , Tom Gallagher , Stanley Perlman , Paul B McCray

A predominately pulmonary activation of complement in a mouse model of severe COVID-19.

bioRxiv : the preprint server for biology

Avec: Peter J Szachowicz , Christine Wohlford-Lenane , Cobey J Heinen , Shreya Ghimire , Biyun Xue , Timothy J Boly , Abhishek Verma , Leila MašinoviĆ , Jennifer R Bermick , Stanley Perlman , David K Meyerholz , Alejandro A Pezzulo , Yuzhou Zhang , Richard J H Smith , Paul B McCray

Il-13 induces loss of CFTR in ionocytes and reduces airway epithelial fluid absorption.

The Journal of clinical investigation

Avec: Guillermo S Romano Ibarra , Lei Lei , Wenjie Yu , Andrew L Thurman , Nicholas D Gansemer , David K Meyerholz , Alejandro A Pezzulo , Paul B McCray , Ian M Thornell , David A Stoltz

Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract.

bioRxiv : the preprint server for biology

Avec: Miguel E Ortiz Bezara , Andrew Thurman , Alejandro A Pezzulo , Mariah R Leidinger , Julia A Klesney-Tait , Philip H Karp , Ping Tan , Christine Wohlford-Lenane , Paul B McCray , David K Meyerholz

Development of a Mouse-Adapted MERS Coronavirus.

Methods in molecular biology (Clifton, N.J.)

Avec: Kun Li , Paul B McCray

Heterogeneous expression of the SARS-Coronavirus-2 receptor ACE2 in the human respiratory tract.

EBioMedicine

Avec: Miguel E Ortiz , Andrew Thurman , Alejandro A Pezzulo , Mariah R Leidinger , Julia A Klesney-Tait , Philip H Karp , Ping Tan , Christine Wohlford-Lenane , Paul B McCray , David K Meyerholz

Analysis of multiple gene co-expression networks to discover interactions favoring CFTR biogenesis and ΔF508-CFTR rescue.

BMC medical genomics

Avec: Matthew D Strub , Long Gao , Kai Tan , Paul B McCray

Lentiviral vectors transduce lung stem cells without disrupting plasticity.

Molecular therapy. Nucleic acids

Avec: Ashley L Cooney , Andrew L Thurman , Paul B McCray , Alejandro A Pezzulo , Patrick L Sinn

Functional correction of CFTR mutations in human airway epithelial cells using adenine base editors.

Nucleic acids research

Avec: Sateesh Krishnamurthy , Soumba Traore , Ashley L Cooney , Christian M Brommel , Katarina Kulhankova , Patrick L Sinn , Gregory A Newby , David R Liu , Paul B McCray

Intersubject Variation in ACE2 Protein Expression in Human Airway Epithelia and Its Relationship to Severe Acute Respiratory Syndrome Coronavirus 2.

The Journal of infectious diseases

Avec: Kun Li , Christine Wohlford-Lenane , Jennifer A Bartlett , Paul B McCray

Gene Therapy Potential for Genetic Disorders of Surfactant Dysfunction.

Frontiers in genome editing

Avec: Ashley L Cooney , Jennifer A Wambach , Patrick L Sinn , Paul B McCray

High ionic strength vector formulations enhance gene transfer to airway epithelia.

bioRxiv : the preprint server for biology

Avec: Ashley L Cooney , Laura Marquez Loza , Kenan Najdawi , Christian M Brommel , Paul B McCray , Patrick L Sinn

High ionic strength vector formulations enhance gene transfer to airway epithelia.

Nucleic acids research

Avec: Ashley L Cooney , Laura Marquez Loza , Kenan Najdawi , Christian M Brommel , Paul B McCray , Patrick L Sinn

Engineered transfer RNAs for suppression of premature termination codons.

Nature communications

Avec: John D Lueck , Jae Seok Yoon , Alfredo Perales-Puchalt , Adam L Mackey , Daniel T Infield , Mark A Behlke , Marshall R Pope , David B Weiner , William R Skach , Paul B McCray , Christopher A Ahern

Single-Dose, Intranasal Immunization with Recombinant Parainfluenza Virus 5 Expressing Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Spike Protein Protects Mice from Fatal MERS-CoV Infection.

mBio

Avec: Kun Li , Zhuo Li , Christine Wohlford-Lenane , David K Meyerholz , Rudragouda Channappanavar , Dong An , Stanley Perlman , Paul B McCray , Biao He

K18-hACE2 Mice for Studies of COVID-19 Treatments and Pathogenesis Including Anosmia.

bioRxiv : the preprint server for biology

Avec: Jian Zheng , Lok-Yin Roy Wong , Kun Li , Abhishek K Verma , Miguel Ortiz , Christine Wohlford-Lenane , Mariah R Leidinger , C Michael Knudson , David K Meyerholz , Paul B McCray , Stanley Perlman

Transcriptomic and Proteostasis Networks of CFTR and the Development of Small Molecule Modulators for the Treatment of Cystic Fibrosis Lung Disease.

Genes

Avec: Matthew D Strub , Paul B McCray

Réseau de co-auteurs

David K Meyerholz 9 collaborations

Christine Wohlford-Lenane 8 collaborations

Ashley L Cooney 7 collaborations

Patrick L Sinn 7 collaborations

Stanley Perlman 6 collaborations

Kun Li 6 collaborations

Alejandro A Pezzulo 5 collaborations

Mariah R Leidinger 3 collaborations

Christian M Brommel 3 collaborations

Ian M Thornell 2 collaborations

David A Stoltz 2 collaborations

Rudragouda Channappanavar 2 collaborations

Jian Zheng 2 collaborations

Sateesh Krishnamurthy 2 collaborations

David R Liu 2 collaborations

Lok-Yin Roy Wong 2 collaborations

Katarina Kulhankova 2 collaborations

Abhishek Verma 2 collaborations

Miguel E Ortiz 2 collaborations

Peter J Szachowicz 2 collaborations

Andrew L Thurman 2 collaborations

Andrew Thurman 2 collaborations

Julia A Klesney-Tait 2 collaborations

Philip H Karp 2 collaborations

Ping Tan 2 collaborations

Matthew D Strub 2 collaborations

Laura Marquez Loza 2 collaborations

Kenan Najdawi 2 collaborations

Brajesh K Singh 1 collaboration

Viral S Shah 1 collaboration

Joseph Zabner 1 collaboration

Anthony R Fehr 1 collaboration

Juan E Abrahante 1 collaboration

Matthias Mack 1 collaboration

Ramakrishna Sompallae 1 collaboration

Suhas Kandimalla 1 collaboration

Gilles Sartre 1 collaboration

Vanessa Théberge 1 collaboration

Stéphanie Hallée 1 collaboration

Anne-Marie Duperré 1 collaboration

Thomas Del'Guidice 1 collaboration

Jean-Pascal Lepetit-Stoffaes 1 collaboration

Xavier Barbeau 1 collaboration

David Guay 1 collaboration

Krishanu Saha 1 collaboration

Erik J Sontheimer 1 collaboration

P J Brooks 1 collaboration

Melinda R Dwinell 1 collaboration

Charles A Gersbach 1 collaboration

Stephen A Murray 1 collaboration

Shengdar Q Tsai 1 collaboration

Ross C Wilson 1 collaboration

Daniel G Anderson 1 collaboration

Aravind Asokan 1 collaboration

Jillian F Banfield 1 collaboration

Krystof S Bankiewicz 1 collaboration

Gang Bao 1 collaboration

Jeff W M Bulte 1 collaboration

Nenad Bursac 1 collaboration

Jarryd M Campbell 1 collaboration

Daniel F Carlson 1 collaboration

Elliot L Chaikof 1 collaboration

Zheng-Yi Chen 1 collaboration

R Holland Cheng 1 collaboration

Karl J Clark 1 collaboration

David T Curiel 1 collaboration

James E Dahlman 1 collaboration

Benjamin E Deverman 1 collaboration

Mary E Dickinson 1 collaboration

Jennifer A Doudna 1 collaboration

Stephen C Ekker 1 collaboration

Marina E Emborg 1 collaboration

Guoping Feng 1 collaboration

Benjamin S Freedman 1 collaboration

David M Gamm 1 collaboration

Guangping Gao 1 collaboration

Ionita C Ghiran 1 collaboration

Peter M Glazer 1 collaboration

Shaoqin Gong 1 collaboration

Jason D Heaney 1 collaboration

Jon D Hennebold 1 collaboration

John T Hinson 1 collaboration

Anastasia Khvorova 1 collaboration

Samira Kiani 1 collaboration

William R Lagor 1 collaboration

Kit S Lam 1 collaboration

Kam W Leong 1 collaboration

Jon E Levine 1 collaboration

Jennifer A Lewis 1 collaboration

Cathleen M Lutz 1 collaboration

Danith H Ly 1 collaboration

Samantha Maragh 1 collaboration

Todd C McDevitt 1 collaboration

Oleg Mirochnitchenko 1 collaboration

Ryuji Morizane 1 collaboration

Niren Murthy 1 collaboration

Randall S Prather 1 collaboration

John A Ronald 1 collaboration

Subhojit Roy 1 collaboration

Sushmita Roy 1 collaboration

Venkata Sabbisetti 1 collaboration

W Mark Saltzman 1 collaboration

Philip J Santangelo 1 collaboration

David J Segal 1 collaboration

Mary Shimoyama 1 collaboration

Melissa C Skala 1 collaboration

Alice F Tarantal 1 collaboration

John C Tilton 1 collaboration

George A Truskey 1 collaboration

Moriel Vandsburger 1 collaboration

Jonathan K Watts 1 collaboration

Kevin D Wells 1 collaboration

Scot A Wolfe 1 collaboration

Qiaobing Xu 1 collaboration

Wen Xue 1 collaboration

Guohua Yi 1 collaboration

Jiangbing Zhou 1 collaboration

None None 1 collaboration

Laura I Marquez Loza 1 collaboration

Qian Dong 1 collaboration

Christoph O Randak 1 collaboration

Stefano Rivella 1 collaboration

Jing Sun 1 collaboration

Zhen Zhuang 1 collaboration

Jincun Zhao 1 collaboration

Chieh-Yu Liang 1 collaboration

Iris Huang 1 collaboration

Julianna Han 1 collaboration

Boopathi Sownthirarajan 1 collaboration

Nathan B Murray 1 collaboration

Mehrnoush Taherzadeh 1 collaboration

Stephanie Archer-Hartmann 1 collaboration

Lauren Pepi 1 collaboration

Senthamizharasi Manivasagam 1 collaboration

Jesse Plung 1 collaboration

Miranda Sturtz 1 collaboration

Yolanda Yu 1 collaboration

Olivia A Vogel 1 collaboration

Matheswaran Kandasamy 1 collaboration

Francoise A Gourronc 1 collaboration

Aloysius J Klingelhutz 1 collaboration

Biswa Choudhury 1 collaboration

Lijun Rong 1 collaboration

Jasmine T Perez 1 collaboration

Parastoo Azadi 1 collaboration

Sriram Neelamegham 1 collaboration

Balaji Manicassamy 1 collaboration

Pengfei Li 1 collaboration

Grant M Hawkins 1 collaboration

Nicholas J Schnicker 1 collaboration

Alejandro Pezullo 1 collaboration

Christine L Wohlford-Lenane 1 collaboration

Tom Kicmal 1 collaboration

Tom Gallagher 1 collaboration

Cobey J Heinen 1 collaboration

Shreya Ghimire 1 collaboration

Biyun Xue 1 collaboration

Timothy J Boly 1 collaboration

Leila MašinoviĆ 1 collaboration

Jennifer R Bermick 1 collaboration

Yuzhou Zhang 1 collaboration

Richard J H Smith 1 collaboration

Guillermo S Romano Ibarra 1 collaboration

Lei Lei 1 collaboration

Wenjie Yu 1 collaboration

Nicholas D Gansemer 1 collaboration

Miguel E Ortiz Bezara 1 collaboration

Long Gao 1 collaboration

Kai Tan 1 collaboration

Soumba Traore 1 collaboration

Gregory A Newby 1 collaboration

Jennifer A Bartlett 1 collaboration

Jennifer A Wambach 1 collaboration

John D Lueck 1 collaboration

Jae Seok Yoon 1 collaboration

Alfredo Perales-Puchalt 1 collaboration

Adam L Mackey 1 collaboration

Daniel T Infield 1 collaboration

Mark A Behlke 1 collaboration

Marshall R Pope 1 collaboration

David B Weiner 1 collaboration

William R Skach 1 collaboration

Christopher A Ahern 1 collaboration

Zhuo Li 1 collaboration

Dong An 1 collaboration

Biao He 1 collaboration

Abhishek K Verma 1 collaboration

Miguel Ortiz 1 collaboration

C Michael Knudson 1 collaboration