Petr Danecek

Affiliations

Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, UK.

Publications (15)

Cardelino: computational integration of somatic clonal substructure and single-cell transcriptomes.

Nature methods

Avec: Davis J McCarthy , Raghd Rostom , Yuanhua Huang , Daniel J Kunz , Petr Danecek , Marc Jan Bonder , Tzachi Hagai , Ruqian Lyu , Auteur inconnu , Wenyi Wang , Daniel J Gaffney , Benjamin D Simons , Oliver Stegle , Sarah A Teichmann

Genetic and chemotherapeutic influences on germline hypermutation.

Nature

Avec: Joanna Kaplanis , Benjamin Ide , Rashesh Sanghvi , Matthew Neville , Petr Danecek , Tim Coorens , Elena Prigmore , Patrick Short , Giuseppe Gallone , Jeremy McRae , Auteur inconnu , Jenny Carmichael , Angela Barnicoat , Helen Firth , Patrick O'Brien , Raheleh Rahbari , Matthew Hurles

Detecting cryptic clinically relevant structural variation in exome-sequencing data increases diagnostic yield for developmental disorders.

American journal of human genetics

Avec: Eugene J Gardner , Alejandro Sifrim , Sarah J Lindsay , Elena Prigmore , Diana Rajan , Petr Danecek , Giuseppe Gallone , Ruth Y Eberhardt , Hilary C Martin , Caroline F Wright , David R FitzPatrick , Helen V Firth , Matthew E Hurles

Substantial somatic genomic variation and selection for BCOR mutations in human induced pluripotent stem cells.

Nature genetics

Avec: Foad J Rouhani , Xueqing Zou , Petr Danecek , Cherif Badja , Tauanne Dias Amarante , Gene Koh , Qianxin Wu , Yasin Memari , Richard Durbin , Inigo Martincorena , Andrew R Bassett , Daniel Gaffney , Serena Nik-Zainal

Insights into human genetic variation and population history from 929 diverse genomes.

Science (New York, N.Y.)

Avec: Anders Bergström , Shane A McCarthy , Ruoyun Hui , Mohamed A Almarri , Qasim Ayub , Petr Danecek , Yuan Chen , Sabine Felkel , Pille Hallast , Jack Kamm , Hélène Blanché , Jean-François Deleuze , Howard Cann , Swapan Mallick , David Reich , Manjinder S Sandhu , Pontus Skoglund , Aylwyn Scally , Yali Xue , Richard Durbin , Chris Tyler-Smith

Contribution of retrotransposition to developmental disorders.

Nature communications

Avec: Eugene J Gardner , Elena Prigmore , Giuseppe Gallone , Petr Danecek , Kaitlin E Samocha , Juliet Handsaker , Sebastian S Gerety , Holly Ironfield , Patrick J Short , Alejandro Sifrim , Tarjinder Singh , Kate E Chandler , Emma Clement , Katherine L Lachlan , Katrina Prescott , Elisabeth Rosser , David R FitzPatrick , Helen V Firth , Matthew E Hurles

De novo variants in the RNU4-2 snRNA cause a frequent neurodevelopmental syndrome.

Nature

Avec: Yuyang Chen , Ruebena Dawes , Hyung Chul Kim , Alicia Ljungdahl , Sarah L Stenton , Susan Walker , Jenny Lord , Gabrielle Lemire , Alexandra C Martin-Geary , Vijay S Ganesh , Jialan Ma , Jamie M Ellingford , Erwan Delage , Elston N D'Souza , Shan Dong , David R Adams , Kirsten Allan , Madhura Bakshi , Erin E Baldwin , Seth I Berger , Jonathan A Bernstein , Ishita Bhatnagar , Ed Blair , Natasha J Brown , Lindsay C Burrage , Kimberly Chapman , David J Coman , Alison G Compton , Chloe A Cunningham , Precilla D'Souza , Petr Danecek , Emmanuèle C Délot , Kerith-Rae Dias , Ellen R Elias , Frances Elmslie , Care-Anne Evans , Lisa Ewans , Kimberly Ezell , Jamie L Fraser , Lyndon Gallacher , Casie A Genetti , Anne Goriely , Christina L Grant , Tobias Haack , Jenny E Higgs , Anjali G Hinch , Matthew E Hurles , Alma Kuechler , Katherine L Lachlan , Seema R Lalani , François Lecoquierre , Elsa Leitão , Anna Le Fevre , Richard J Leventer , Jan E Liebelt , Sarah Lindsay , Paul J Lockhart , Alan S Ma , Ellen F Macnamara , Sahar Mansour , Taylor M Maurer , Hector R Mendez , Kay Metcalfe , Stephen B Montgomery , Mariya Moosajee , Marie-Cécile Nassogne , Serena Neumann , Michael O'Donoghue , Melanie O'Leary , Elizabeth E Palmer , Nikhil Pattani , John Phillips , Georgia Pitsava , Ryan Pysar , Heidi L Rehm , Chloe M Reuter , Nicole Revencu , Angelika Riess , Rocio Rius , Lance Rodan , Tony Roscioli , Jill A Rosenfeld , Rani Sachdev , Charles J Shaw-Smith , Cas Simons , Sanjay M Sisodiya , Penny Snell , Laura St Clair , Zornitza Stark , Helen S Stewart , Tiong Yang Tan , Natalie B Tan , Suzanna E L Temple , David R Thorburn , Cynthia J Tifft , Eloise Uebergang , Grace E VanNoy , Pradeep Vasudevan , Eric Vilain , David H Viskochil , Laura Wedd , Matthew T Wheeler , Susan M White , Monica Wojcik , Lynne A Wolfe , Zoe Wolfenson , Caroline F Wright , Changrui Xiao , David Zocche , John L Rubenstein , Eirene Markenscoff-Papadimitriou , Sebastian M Fica , Diana Baralle , Christel Depienne , Daniel G MacArthur , Joanna M M Howson , Stephan J Sanders , Anne O'Donnell-Luria , Nicola Whiffin

Evidence for 28 genetic disorders discovered by combining healthcare and research data.

Nature

Avec: Joanna Kaplanis , Kaitlin E Samocha , Laurens Wiel , Zhancheng Zhang , Kevin J Arvai , Ruth Y Eberhardt , Giuseppe Gallone , Stefan H Lelieveld , Hilary C Martin , Jeremy F McRae , Patrick J Short , Rebecca I Torene , Elke de Boer , Petr Danecek , Eugene J Gardner , Ni Huang , Jenny Lord , Iñigo Martincorena , Rolph Pfundt , Margot R F Reijnders , Alison Yeung , Helger G Yntema , Auteur inconnu , Lisenka E L M Vissers , Jane Juusola , Caroline F Wright , Han G Brunner , Helen V Firth , David R FitzPatrick , Jeffrey C Barrett , Matthew E Hurles , Christian Gilissen , Kyle Retterer

Very low-depth whole-genome sequencing in complex trait association studies.

Bioinformatics (Oxford, England)

Avec: Arthur Gilly , Lorraine Southam , Daniel Suveges , Karoline Kuchenbaecker , Rachel Moore , Giorgio E M Melloni , Konstantinos Hatzikotoulas , Aliki-Eleni Farmaki , Graham Ritchie , Jeremy Schwartzentruber , Petr Danecek , Britt Kilian , Martin O Pollard , Xiangyu Ge , Emmanouil Tsafantakis , George Dedoussis , Eleftheria Zeggini

Non-coding region variants upstream of MEF2C cause severe developmental disorder through three distinct loss-of-function mechanisms.

American journal of human genetics

Avec: Caroline F Wright , Nicholas M Quaife , Laura Ramos-Hernández , Petr Danecek , Matteo P Ferla , Kaitlin E Samocha , Joanna Kaplanis , Eugene J Gardner , Ruth Y Eberhardt , Katherine R Chao , Konrad J Karczewski , Joannella Morales , Giuseppe Gallone , Meena Balasubramanian , Siddharth Banka , Lianne Gompertz , Bronwyn Kerr , Amelia Kirby , Sally A Lynch , Jenny E V Morton , Hailey Pinz , Francis H Sansbury , Helen Stewart , Britton D Zuccarelli , Auteur inconnu , Stuart A Cook , Jenny C Taylor , Jane Juusola , Kyle Retterer , Helen V Firth , Matthew E Hurles , Enrique Lara-Pezzi , Paul J R Barton , Nicola Whiffin

Twelve years of SAMtools and BCFtools.

GigaScience

Avec: Petr Danecek , James K Bonfield , Jennifer Liddle , John Marshall , Valeriu Ohan , Martin O Pollard , Andrew Whitwham , Thomas Keane , Shane A McCarthy , Robert M Davies , Heng Li

HTSlib: C library for reading/writing high-throughput sequencing data.

GigaScience

Avec: James K Bonfield , John Marshall , Petr Danecek , Heng Li , Valeriu Ohan , Andrew Whitwham , Thomas Keane , Robert M Davies

Somatic mutations alter the differentiation outcomes of iPSC-derived neurons.

Cell genomics

Avec: Pau Puigdevall , Julie Jerber , Petr Danecek , Sergi Castellano , Helena Kilpinen

Genomic Diagnosis of Rare Pediatric Disease in the United Kingdom and Ireland.

The New England journal of medicine

Avec: Caroline F Wright , Patrick Campbell , Ruth Y Eberhardt , Stuart Aitken , Daniel Perrett , Simon Brent , Petr Danecek , Eugene J Gardner , V Kartik Chundru , Sarah J Lindsay , Katrina Andrews , Juliet Hampstead , Joanna Kaplanis , Kaitlin E Samocha , Anna Middleton , Julia Foreman , Rachel J Hobson , Michael J Parker , Hilary C Martin , David R FitzPatrick , Matthew E Hurles , Helen V Firth , Auteur inconnu

Federated analysis of autosomal recessive coding variants in 29,745 developmental disorder patients from diverse populations.

Nature genetics

Avec: V Kartik Chundru , Zhancheng Zhang , Klaudia Walter , Sarah J Lindsay , Petr Danecek , Ruth Y Eberhardt , Eugene J Gardner , Daniel S Malawsky , Emilie M Wigdor , Rebecca Torene , Kyle Retterer , Caroline F Wright , Hildur Ólafsdóttir , Maria J Guillen Sacoto , Akif Ayaz , Ismail Hakki Akbeyaz , Dilşad Türkdoğan , Aaisha Ibrahim Al Balushi , Aida Bertoli-Avella , Peter Bauer , Emmanuelle Szenker-Ravi , Bruno Reversade , Kirsty McWalter , Eamonn Sheridan , Helen V Firth , Matthew E Hurles , Kaitlin E Samocha , Vincent D Ustach , Hilary C Martin

Réseau de co-auteurs

Matthew E Hurles 7 collaborations

Eugene J Gardner 6 collaborations

Caroline F Wright 6 collaborations

Helen V Firth 6 collaborations

None None 5 collaborations

Giuseppe Gallone 5 collaborations

Ruth Y Eberhardt 5 collaborations

Kaitlin E Samocha 5 collaborations

Joanna Kaplanis 4 collaborations

Hilary C Martin 4 collaborations

David R FitzPatrick 4 collaborations

Elena Prigmore 3 collaborations

Sarah J Lindsay 3 collaborations

Kyle Retterer 3 collaborations

Alejandro Sifrim 2 collaborations

Richard Durbin 2 collaborations

Shane A McCarthy 2 collaborations

Patrick J Short 2 collaborations

Katherine L Lachlan 2 collaborations

Jenny Lord 2 collaborations

Nicola Whiffin 2 collaborations

Zhancheng Zhang 2 collaborations

Jane Juusola 2 collaborations

Martin O Pollard 2 collaborations

James K Bonfield 2 collaborations

John Marshall 2 collaborations

Valeriu Ohan 2 collaborations

Andrew Whitwham 2 collaborations

Thomas Keane 2 collaborations

Robert M Davies 2 collaborations

Heng Li 2 collaborations

V Kartik Chundru 2 collaborations

Davis J McCarthy 1 collaboration

Raghd Rostom 1 collaboration

Yuanhua Huang 1 collaboration

Daniel J Kunz 1 collaboration

Marc Jan Bonder 1 collaboration

Tzachi Hagai 1 collaboration

Ruqian Lyu 1 collaboration

Wenyi Wang 1 collaboration

Daniel J Gaffney 1 collaboration

Benjamin D Simons 1 collaboration

Oliver Stegle 1 collaboration

Sarah A Teichmann 1 collaboration

Benjamin Ide 1 collaboration

Rashesh Sanghvi 1 collaboration

Matthew Neville 1 collaboration

Tim Coorens 1 collaboration

Patrick Short 1 collaboration

Jeremy McRae 1 collaboration

Jenny Carmichael 1 collaboration

Angela Barnicoat 1 collaboration

Helen Firth 1 collaboration

Patrick O'Brien 1 collaboration

Raheleh Rahbari 1 collaboration

Matthew Hurles 1 collaboration

Diana Rajan 1 collaboration

Foad J Rouhani 1 collaboration

Xueqing Zou 1 collaboration

Cherif Badja 1 collaboration

Tauanne Dias Amarante 1 collaboration

Gene Koh 1 collaboration

Qianxin Wu 1 collaboration

Yasin Memari 1 collaboration

Inigo Martincorena 1 collaboration

Andrew R Bassett 1 collaboration

Daniel Gaffney 1 collaboration

Serena Nik-Zainal 1 collaboration

Anders Bergström 1 collaboration

Ruoyun Hui 1 collaboration

Mohamed A Almarri 1 collaboration

Qasim Ayub 1 collaboration

Yuan Chen 1 collaboration

Sabine Felkel 1 collaboration

Pille Hallast 1 collaboration

Jack Kamm 1 collaboration

Hélène Blanché 1 collaboration

Jean-François Deleuze 1 collaboration

Howard Cann 1 collaboration

Swapan Mallick 1 collaboration

David Reich 1 collaboration

Manjinder S Sandhu 1 collaboration

Pontus Skoglund 1 collaboration

Aylwyn Scally 1 collaboration

Yali Xue 1 collaboration

Chris Tyler-Smith 1 collaboration

Juliet Handsaker 1 collaboration

Sebastian S Gerety 1 collaboration

Holly Ironfield 1 collaboration

Tarjinder Singh 1 collaboration

Kate E Chandler 1 collaboration

Emma Clement 1 collaboration

Katrina Prescott 1 collaboration

Elisabeth Rosser 1 collaboration

Yuyang Chen 1 collaboration

Ruebena Dawes 1 collaboration

Hyung Chul Kim 1 collaboration

Alicia Ljungdahl 1 collaboration

Sarah L Stenton 1 collaboration

Susan Walker 1 collaboration

Gabrielle Lemire 1 collaboration

Alexandra C Martin-Geary 1 collaboration

Vijay S Ganesh 1 collaboration

Jialan Ma 1 collaboration

Jamie M Ellingford 1 collaboration

Erwan Delage 1 collaboration

Elston N D'Souza 1 collaboration

Shan Dong 1 collaboration

David R Adams 1 collaboration

Kirsten Allan 1 collaboration

Madhura Bakshi 1 collaboration

Erin E Baldwin 1 collaboration

Seth I Berger 1 collaboration

Jonathan A Bernstein 1 collaboration

Ishita Bhatnagar 1 collaboration

Ed Blair 1 collaboration

Natasha J Brown 1 collaboration

Lindsay C Burrage 1 collaboration

Kimberly Chapman 1 collaboration

David J Coman 1 collaboration

Alison G Compton 1 collaboration

Chloe A Cunningham 1 collaboration

Precilla D'Souza 1 collaboration

Emmanuèle C Délot 1 collaboration

Kerith-Rae Dias 1 collaboration

Ellen R Elias 1 collaboration

Frances Elmslie 1 collaboration

Care-Anne Evans 1 collaboration

Lisa Ewans 1 collaboration

Kimberly Ezell 1 collaboration

Jamie L Fraser 1 collaboration

Lyndon Gallacher 1 collaboration

Casie A Genetti 1 collaboration

Anne Goriely 1 collaboration

Christina L Grant 1 collaboration

Tobias Haack 1 collaboration

Jenny E Higgs 1 collaboration

Anjali G Hinch 1 collaboration

Alma Kuechler 1 collaboration

Seema R Lalani 1 collaboration

François Lecoquierre 1 collaboration

Elsa Leitão 1 collaboration

Anna Le Fevre 1 collaboration

Richard J Leventer 1 collaboration

Jan E Liebelt 1 collaboration

Sarah Lindsay 1 collaboration

Paul J Lockhart 1 collaboration

Alan S Ma 1 collaboration

Ellen F Macnamara 1 collaboration

Sahar Mansour 1 collaboration

Taylor M Maurer 1 collaboration

Hector R Mendez 1 collaboration

Kay Metcalfe 1 collaboration

Stephen B Montgomery 1 collaboration

Mariya Moosajee 1 collaboration

Marie-Cécile Nassogne 1 collaboration

Serena Neumann 1 collaboration

Michael O'Donoghue 1 collaboration

Melanie O'Leary 1 collaboration

Elizabeth E Palmer 1 collaboration

Nikhil Pattani 1 collaboration

John Phillips 1 collaboration

Georgia Pitsava 1 collaboration

Ryan Pysar 1 collaboration

Heidi L Rehm 1 collaboration

Chloe M Reuter 1 collaboration

Nicole Revencu 1 collaboration

Angelika Riess 1 collaboration

Rocio Rius 1 collaboration

Lance Rodan 1 collaboration

Tony Roscioli 1 collaboration

Jill A Rosenfeld 1 collaboration

Rani Sachdev 1 collaboration

Charles J Shaw-Smith 1 collaboration

Cas Simons 1 collaboration

Sanjay M Sisodiya 1 collaboration

Penny Snell 1 collaboration

Laura St Clair 1 collaboration

Zornitza Stark 1 collaboration

Helen S Stewart 1 collaboration

Tiong Yang Tan 1 collaboration

Natalie B Tan 1 collaboration

Suzanna E L Temple 1 collaboration

David R Thorburn 1 collaboration

Cynthia J Tifft 1 collaboration

Eloise Uebergang 1 collaboration

Grace E VanNoy 1 collaboration

Pradeep Vasudevan 1 collaboration

Eric Vilain 1 collaboration

David H Viskochil 1 collaboration

Laura Wedd 1 collaboration

Matthew T Wheeler 1 collaboration

Susan M White 1 collaboration

Monica Wojcik 1 collaboration

Lynne A Wolfe 1 collaboration

Zoe Wolfenson 1 collaboration

Changrui Xiao 1 collaboration

David Zocche 1 collaboration

John L Rubenstein 1 collaboration

Eirene Markenscoff-Papadimitriou 1 collaboration

Sebastian M Fica 1 collaboration

Diana Baralle 1 collaboration

Christel Depienne 1 collaboration

Daniel G MacArthur 1 collaboration

Joanna M M Howson 1 collaboration

Stephan J Sanders 1 collaboration

Anne O'Donnell-Luria 1 collaboration

Laurens Wiel 1 collaboration

Kevin J Arvai 1 collaboration

Stefan H Lelieveld 1 collaboration

Jeremy F McRae 1 collaboration

Rebecca I Torene 1 collaboration

Elke de Boer 1 collaboration

Ni Huang 1 collaboration

Iñigo Martincorena 1 collaboration

Rolph Pfundt 1 collaboration

Margot R F Reijnders 1 collaboration

Alison Yeung 1 collaboration

Helger G Yntema 1 collaboration

Lisenka E L M Vissers 1 collaboration

Han G Brunner 1 collaboration

Jeffrey C Barrett 1 collaboration

Christian Gilissen 1 collaboration

Arthur Gilly 1 collaboration

Lorraine Southam 1 collaboration

Daniel Suveges 1 collaboration

Karoline Kuchenbaecker 1 collaboration

Rachel Moore 1 collaboration

Giorgio E M Melloni 1 collaboration

Konstantinos Hatzikotoulas 1 collaboration

Aliki-Eleni Farmaki 1 collaboration

Graham Ritchie 1 collaboration

Jeremy Schwartzentruber 1 collaboration

Britt Kilian 1 collaboration

Xiangyu Ge 1 collaboration

Emmanouil Tsafantakis 1 collaboration

George Dedoussis 1 collaboration

Eleftheria Zeggini 1 collaboration

Nicholas M Quaife 1 collaboration

Laura Ramos-Hernández 1 collaboration

Matteo P Ferla 1 collaboration

Katherine R Chao 1 collaboration

Konrad J Karczewski 1 collaboration

Joannella Morales 1 collaboration

Meena Balasubramanian 1 collaboration

Siddharth Banka 1 collaboration

Lianne Gompertz 1 collaboration

Bronwyn Kerr 1 collaboration

Amelia Kirby 1 collaboration

Sally A Lynch 1 collaboration

Jenny E V Morton 1 collaboration

Hailey Pinz 1 collaboration

Francis H Sansbury 1 collaboration

Helen Stewart 1 collaboration

Britton D Zuccarelli 1 collaboration

Stuart A Cook 1 collaboration

Jenny C Taylor 1 collaboration

Enrique Lara-Pezzi 1 collaboration

Paul J R Barton 1 collaboration

Jennifer Liddle 1 collaboration

Pau Puigdevall 1 collaboration

Julie Jerber 1 collaboration

Sergi Castellano 1 collaboration

Helena Kilpinen 1 collaboration

Patrick Campbell 1 collaboration

Stuart Aitken 1 collaboration

Daniel Perrett 1 collaboration

Simon Brent 1 collaboration

Katrina Andrews 1 collaboration

Juliet Hampstead 1 collaboration

Anna Middleton 1 collaboration

Julia Foreman 1 collaboration

Rachel J Hobson 1 collaboration

Michael J Parker 1 collaboration

Klaudia Walter 1 collaboration

Daniel S Malawsky 1 collaboration

Emilie M Wigdor 1 collaboration

Rebecca Torene 1 collaboration

Hildur Ólafsdóttir 1 collaboration

Maria J Guillen Sacoto 1 collaboration

Akif Ayaz 1 collaboration

Ismail Hakki Akbeyaz 1 collaboration

Dilşad Türkdoğan 1 collaboration

Aaisha Ibrahim Al Balushi 1 collaboration

Aida Bertoli-Avella 1 collaboration

Peter Bauer 1 collaboration

Emmanuelle Szenker-Ravi 1 collaboration

Bruno Reversade 1 collaboration

Kirsty McWalter 1 collaboration

Eamonn Sheridan 1 collaboration

Vincent D Ustach 1 collaboration