Rafael Balaña-Fouce

Affiliations

Departamento de Ciencias Biomédicas, Universidad de León, León, Spain.

Publications (44)

A chronic bioluminescent model of experimental visceral leishmaniasis for accelerating drug discovery.

PLoS neglected tropical diseases

Avec: Raquel Álvarez-Velilla , Maria Del Camino Gutiérrez-Corbo , Carmen Punzón , Maria Yolanda Pérez-Pertejo , Rafael Balaña-Fouce , Manuel Fresno , Rosa María Reguera

Resistance to Experimental Visceral Leishmaniasis in Mice Infected With

Frontiers in immunology

Avec: Manuel Soto , Laura Ramírez , José Carlos Solana , Emma C L Cook , Elena Hernández-García , Sara Charro-Zanca , Ana Redondo-Urzainqui , Rosa M Reguera , Rafael Balaña-Fouce , Salvador Iborra

Bioluminescent Imaging Identifies Thymus, As Overlooked Colonized Organ, in a Chronic Model of

ACS infectious diseases

Avec: Bárbara Domínguez-Asenjo , Camino Gutiérrez-Corbo , Yolanda Pérez-Pertejo , Salvador Iborra , Rafael Balaña-Fouce , Rosa M Reguera

Polyamine Metabolism for Drug Intervention in Trypanosomatids.

Pathogens (Basel, Switzerland)

Avec: Yolanda Pérez-Pertejo , Carlos García-Estrada , María Martínez-Valladares , Sankaranarayanan Murugesan , Rosa M Reguera , Rafael Balaña-Fouce

Microbial community in resistant and susceptible Churra sheep infected by Teladorsagia circumcincta.

Scientific reports

Avec: Verónica Castilla Gómez de Agüero , Cristina Esteban-Blanco , Héctor Argüello , Elora Valderas-García , Sonia Andrés , Rafael Balaña-Fouce , Juan José Arranz , Beatriz Gutiérrez-Gil , María Martínez-Valladares

Miltefosine and Nifuratel Combination: A Promising Therapy for the Treatment of

International journal of molecular sciences

Avec: Estela Melcon-Fernandez , Giulio Galli , Carlos García-Estrada , Rafael Balaña-Fouce , Rosa M Reguera , Yolanda Pérez-Pertejo

Further Investigations of Nitroheterocyclic Compounds as Potential Antikinetoplastid Drug Candidates.

Biomolecules

Avec: Carlos García-Estrada , Yolanda Pérez-Pertejo , Bárbara Domínguez-Asenjo , Vanderlan Nogueira Holanda , Sankaranarayanan Murugesan , María Martínez-Valladares , Rafael Balaña-Fouce , Rosa M Reguera

DNA flowerstructure co-localizes with human pathogens in infected macrophages.

Nucleic acids research

Avec: Oskar Franch , Camino Gutiérrez-Corbo , Bárbara Domínguez-Asenjo , Thomas Boesen , Pia Bomholt Jensen , Lene N Nejsum , Josephine Geertsen Keller , Simon Pagaard Nielsen , Prakruti R Singh , Rajiv Kumar Jha , Valakunja Nagaraja , Rafael Balaña-Fouce , Yi-Ping Ho , Rosa María Reguera , Birgitta Ruth Knudsen

Screening Marine Natural Products for New Drug Leads against Trypanosomatids and Malaria.

Marine drugs

Avec: María Álvarez-Bardón , Yolanda Pérez-Pertejo , César Ordóñez , Daniel Sepúlveda-Crespo , Nestor M Carballeira , Babu L Tekwani , Sankaranarayanan Murugesan , Maria Martinez-Valladares , Carlos García-Estrada , Rosa M Reguera , Rafael Balaña-Fouce

Teladorsagia circumcincta beta tubulin: the presence of the E198L polymorphism on its own is associated with benzimidazole resistance.

Parasites & vectors

Avec: María Martínez-Valladares , Elora Valderas-García , Javier Gandasegui , Philip Skuce , Alison Morrison , Verónica Castilla Gómez de Agüero , Maria Cambra-Pellejà , Rafael Balaña-Fouce , Francisco A Rojo-Vázquez

Novel phenanthridine amide analogs as potential anti-leishmanial agents: In vitro and in silico insights.

Bioorganic chemistry

Avec: Adinarayana Nandikolla , Singireddi Srinivasarao , Banoth Karan Kumar , Sankaranarayanan Murugesan , Himanshu Aggarwal , Rafael Balaña-Fouce , Estela Melcón-Fernandez , Yolanda Pérez-Pertejo , Kondapalli Venkata Gowri Chandra Sekhar

Anthelmintic activity of aminoalcohol and diamine derivatives against the gastrointestinal nematode Teladorsagia circumcincta.

Veterinary parasitology

Avec: Elora Valderas-García , Jennifer de la Vega , María Álvarez Bardón , Verónica Castilla Gómez de Agüero , Ricardo Escarcena , José Luis López-Pérez , Francisco A Rojo-Vázquez , Arturo San Feliciano , Esther Del Olmo , Rafael Balaña-Fouce , María Martínez-Valladares

Characterization of the Gene Encoding S-adenosyl-L-methionine (AdoMet) Synthetase in

Microorganisms

Avec: Rebeca Domínguez-Santos , Katarina Kosalková , Isabel-Clara Sánchez-Orejas , Carlos Barreiro , Yolanda Pérez-Pertejo , Rosa M Reguera , Rafael Balaña-Fouce , Carlos García-Estrada

Benzimidazole and aminoalcohol derivatives show in vitro anthelmintic activity against Trichuris muris and Heligmosomoides polygyrus.

Parasites & vectors

Avec: Elora Valderas-García , Cécile Häberli , María Álvarez-Bardón , Nerea Escala , Verónica Castilla-Gómez de Agüero , Jennifer de la Vega , Esther Del Olmo , Rafael Balaña-Fouce , Jennifer Keiser , María Martínez-Valladares

Targeting Trypanothione Metabolism in Trypanosomatids.

Molecules (Basel, Switzerland)

Avec: María-Cristina González-Montero , Julia Andrés-Rodríguez , Nerea García-Fernández , Yolanda Pérez-Pertejo , Rosa M Reguera , Rafael Balaña-Fouce , Carlos García-Estrada

Reproduction in Trypanosomatids: Past and Present.

Biology

Avec: Camino Gutiérrez-Corbo , Bárbara Domínguez-Asenjo , María Martínez-Valladares , Yolanda Pérez-Pertejo , Carlos García-Estrada , Rafael Balaña-Fouce , Rosa M Reguera

Effect of level of infection by gastrointestinal nematodes and anthelmintic treatment on milk yield in dairy sheep.

Parasite (Paris, France)

Avec: María Martínez-Valladares , Elías Martín-Ramos , Myriam Esteban-Ballesteros , Rafael Balaña-Fouce , Francisco Antonio Rojo-Vázquez

Recent Update on the Anti-infective Potential of β-carboline Analogs.

Mini reviews in medicinal chemistry

Avec: Faheem , Banoth Karan Kumar , Kondapalli Venkata Gowri Chandra Sekhar , Selvaraj Kunjiappan , Joazaizulfazli Jamalis , Rafael Balaña-Fouce , Murugesan Sankaranarayanan

Zoonotic Implications of

Pathogens (Basel, Switzerland)

Avec: Maria Cambra-Pellejà , Javier Gandasegui , Rafael Balaña-Fouce , José Muñoz , María Martínez-Valladares

Ex Vivo Phenotypic Screening of Two Small Repurposing Drug Collections Identifies Nifuratel as a Potential New Treatment against Visceral and Cutaneous Leishmaniasis.

ACS infectious diseases

Avec: Bárbara Domínguez-Asenjo , Camino Gutiérrez-Corbo , María Álvarez-Bardón , Yolanda Pérez-Pertejo , Rafael Balaña-Fouce , Rosa M Reguera

New benzimidazole derivative compounds with in vitro fasciolicidal properties.

Parasites & vectors

Avec: Elora Valderas-García , Verónica Castilla-Gómez de Agüero , Laura González Del Palacio , Giulio Galli , Nerea Escala , Marta Ruiz-Somacarrera , Marta González-Warleta , Esther Del Olmo , Rafael Balaña-Fouce , María Martínez-Valladares

Treatment and Healing of Leishmaniasis in a Wolf in Semi-Captivity Regime from an Educational Center of Zamora Province (Spain).

Animals : an open access journal from MDPI

Avec: Javier Merino-Goyenechea , Jesús Palacios-Alberti , Tomás Yanes-Martínez , María Martínez-Valladares , Rafael Balaña-Fouce

Drug discovery technologies: Caenorhabditis elegans as a model for anthelmintic therapeutics.

Medicinal research reviews

Avec: Daniel Sepúlveda-Crespo , Rosa M Reguera , Francisco Rojo-Vázquez , Rafael Balaña-Fouce , María Martínez-Valladares

DNA Topoisomerases of Leishmania Parasites; Druggable Targets for Drug Discovery.

Current medicinal chemistry

Avec: Rosa M Reguera , Ehab K Elmahallawy , Carlos García-Estrada , Rubén Carbajo-Andrés , Rafael Balaña-Fouce

Topoisomerase IB poisons induce histone H2A phosphorylation as a response to DNA damage in Leishmania infantum.

International journal for parasitology. Drugs and drug resistance

Avec: Camino Gutiérrez-Corbo , Raquel Álvarez-Velilla , Rosa M Reguera , Carlos García-Estrada , Mark Cushman , Rafael Balaña-Fouce , Yolanda Pérez-Pertejo

Walking a tightrope: drug discovery in visceral leishmaniasis.

Drug discovery today

Avec: Rafael Balaña-Fouce , M Yolanda Pérez Pertejo , Bárbara Domínguez-Asenjo , Camino Gutiérrez-Corbo , Rosa M Reguera

Antileishmanial activity of terpenylquinones on Leishmania infantum and their effects on Leishmania topoisomerase IB.

International journal for parasitology. Drugs and drug resistance

Avec: Yolanda Pérez-Pertejo , José M Escudero-Martínez , Rosa M Reguera , Rafael Balaña-Fouce , Pablo A García , Pablo G Jambrina , Arturo San Feliciano , María-Ángeles Castro

Antiparasitic effect of synthetic aromathecins on Leishmania infantum.

BMC veterinary research

Avec: Rosa M Reguera , Raquel Álvarez-Velilla , Bárbara Domínguez-Asenjo , Camino Gutiérrez-Corbo , Rafael Balaña-Fouce , Mark Cushman , Yolanda Pérez-Pertejo

Antileishmanial activity of new hybrid tetrahydroquinoline and quinoline derivatives with phosphorus substituents.

European journal of medicinal chemistry

Avec: Ana Tejería , Yolanda Pérez-Pertejo , Rosa M Reguera , Rubén Carbajo-Andrés , Rafael Balaña-Fouce , Concepción Alonso , Endika Martin-Encinas , Asier Selas , Gloria Rubiales , Francisco Palacios

Hybrid Quinolinyl Phosphonates as Heterocyclic Carboxylate Isosteres: Synthesis and Biological Evaluation against Topoisomerase 1B (TOP1B).

Pharmaceuticals (Basel, Switzerland)

Avec: Asier Selas , María Fuertes , Estela Melcón-Fernández , Yolanda Pérez-Pertejo , Rosa M Reguera , Rafael Balaña-Fouce , Birgitta R Knudsen , Francisco Palacios , Concepcion Alonso

Gel-Free Tools for Quick and Simple Screening of Anti-Topoisomerase 1 Compounds.

Pharmaceuticals (Basel, Switzerland)

Avec: Josephine Geertsen Keller , Kamilla Vandsø Petersen , Karol Mizielinski , Celine Thiesen , Lotte Bjergbæk , Rosa M Reguera , Yolanda Pérez-Pertejo , Rafael Balaña-Fouce , Angela Trejo , Carme Masdeu , Concepcion Alonso , Birgitta R Knudsen , Cinzia Tesauro

Promising effects of 1,8 Cineole to control Giardia lamblia infection: Targeting the inflammation, oxidative stress, and infectivity.

Acta tropica

Avec: Leila Masoori , Amal Khudair Khalaf , Fatemeh Ezatkhah , Rafael Balaña-Fouce , Hossein Mahmoudvand

Mannose-Decorated Dendritic Polyglycerol Nanocarriers Drive Antiparasitic Drugs To

Pharmaceutics

Avec: Laura I Vossen , Bárbara Domínguez-Asenjo , Camino Gutiérrez-Corbo , M Yolanda Pérez-Pertejo , Rafael Balaña-Fouce , Rosa María Reguera , Marcelo Calderón

In vitro anthelmintic activity and safety of different plant species against the ovine gastrointestinal nematode Teladorsagia circumcincta.

Research in veterinary science

Avec: Myriam Esteban-Ballesteros , Jaime Sanchis , Camino Gutiérrez-Corbo , Rafael Balaña-Fouce , Francisco A Rojo-Vázquez , Camino González-Lanza , María Martínez-Valladares

Synthesis, bioevaluation and docking studies of some 2-phenyl-1H-benzimidazole derivatives as anthelminthic agents against the nematode Teladorsagia circumcincta.

European journal of medicinal chemistry

Avec: Nerea Escala , Elora Valderas-García , María Álvarez Bardón , Verónica Castilla Gómez de Agüero , Ricardo Escarcena , José Luis López-Pérez , Francisco A Rojo-Vázquez , Arturo San Feliciano , Rafael Balaña-Fouce , María Martínez-Valladares , Esther Del Olmo

Druggable targets of SARS-CoV-2 and treatment opportunities for COVID-19.

Bioorganic chemistry

Avec: Faheem , Banoth Karan Kumar , Kondapalli Venkata Gowri Chandra Sekhar , Selvaraj Kunjiappan , Joazaizulfazli Jamalis , Rafael Balaña-Fouce , Babu L Tekwani , Murugesan Sankaranarayanan

Improving stool sample processing and pyrosequencing for quantifying benzimidazole resistance alleles in Trichuris trichiura and Necator americanus pooled eggs.

Parasites & vectors

Avec: Javier Gandasegui , Berta Grau-Pujol , María Cambra-Pelleja , Valdemiro Escola , Maria Antonietta Demontis , Anelsio Cossa , José Carlos Jamine , Rafael Balaña-Fouce , Lisette van Lieshout , José Muñoz , María Martínez-Valladares , Auteur inconnu

Axenic interspecies and intraclonal hybrid formation in Leishmania: Successful crossings between visceral and cutaneous strains.

PLoS neglected tropical diseases

Avec: Camino Gutiérrez-Corbo , Bárbara Domínguez-Asenjo , Yolanda Pérez-Pertejo , Carlos García-Estrada , Felio J Bello , Rafael Balaña-Fouce , Rosa M Reguera

Secretory IgA as Biomarker for Gastrointestinal Nematodes Natural Infection in Different Breed Sheep.

Animals : an open access journal from MDPI

Avec: Verónica Castilla Gómez de Agüero , Elora Valderas-García , Laura González Del Palacio , F Javier Giráldez , Rafael Balaña-Fouce , María Martínez-Valladares

Novel compound shows in vivo anthelmintic activity in gerbils and sheep infected by Haemonchus contortus.

Scientific reports

Avec: Elora Valderas-García , Nerea Escala , María Álvarez-Bardón , Verónica Castilla-Gómez de Agüero , Maria Cambra-Pellejà , Laura González Del Palacio , Raquel Vallejo García , Jennifer de la Vega , Arturo San Feliciano , Esther Del Olmo , María Martínez-Valladares , Rafael Balaña-Fouce

Molecular-level strategic goals and repressors in Leishmaniasis - Integrated data to accelerate target-based heterocyclic scaffolds.

European journal of medicinal chemistry

Avec: M Abirami , Banoth Karan Kumar , Faheem , Sanchita Dey , Samridhi Johri , Rosa M Reguera , Rafael Balaña-Fouce , Kondapalli Venkata Gowri Chandra Sekhar , Murugesan Sankaranarayanan

Antileishmanial Effect of 1,5- and 1,8-Substituted Fused Naphthyridines.

Molecules (Basel, Switzerland)

Avec: Estela Melcón-Fernandez , Endika Martín-Encinas , Francisco Palacios , Gulio Galli , Rosa M Reguera , María Martínez-Valladares , Rafael Balaña-Fouce , Concepción Alonso , Yolanda Pérez-Pertejo

In Vitro and Ex Vivo Synergistic Effect of Pyrvinium Pamoate Combined with Miltefosine and Paromomycin against

Tropical medicine and infectious disease

Avec: Estela Melcón-Fernández , Giulio Galli , Rafael Balaña-Fouce , Nerea García-Fernández , María Martínez-Valladares , Rosa M Reguera , Carlos García-Estrada , Yolanda Pérez-Pertejo

Evaluating alternative compounds for strongyloidiasis therapy: Novel insights from larval migration inhibition test.

PLoS neglected tropical diseases

Avec: María Cambra-Pellejà , Elora Valderas-García , Rafael Balaña-Fouce , Jennifer de la Vega , Esther Del Olmo , Jennifer Antwi-Ekwuruke , Lara Linnemann , Lennart Heepmann , Minka Breloer , María Martínez-Valladares

Réseau de co-auteurs

Rosa M Reguera 23 collaborations

María Martínez-Valladares 20 collaborations

Yolanda Pérez-Pertejo 19 collaborations

Carlos García-Estrada 11 collaborations

Camino Gutiérrez-Corbo 10 collaborations

Bárbara Domínguez-Asenjo 9 collaborations

Elora Valderas-García 9 collaborations

Esther Del Olmo 6 collaborations

Verónica Castilla Gómez de Agüero 5 collaborations

Sankaranarayanan Murugesan 4 collaborations

María Álvarez-Bardón 4 collaborations

Francisco A Rojo-Vázquez 4 collaborations

Banoth Karan Kumar 4 collaborations

Kondapalli Venkata Gowri Chandra Sekhar 4 collaborations

Jennifer de la Vega 4 collaborations

Arturo San Feliciano 4 collaborations

Nerea Escala 4 collaborations

Raquel Álvarez-Velilla 3 collaborations

Rosa María Reguera 3 collaborations

Giulio Galli 3 collaborations

Javier Gandasegui 3 collaborations

Maria Cambra-Pellejà 3 collaborations

Verónica Castilla-Gómez de Agüero 3 collaborations

None Faheem 3 collaborations

Murugesan Sankaranarayanan 3 collaborations

Laura González Del Palacio 3 collaborations

Francisco Palacios 3 collaborations

Salvador Iborra 2 collaborations

Josephine Geertsen Keller 2 collaborations

Daniel Sepúlveda-Crespo 2 collaborations

Babu L Tekwani 2 collaborations

Estela Melcón-Fernandez 2 collaborations

María Álvarez Bardón 2 collaborations

Ricardo Escarcena 2 collaborations

José Luis López-Pérez 2 collaborations

Nerea García-Fernández 2 collaborations

Myriam Esteban-Ballesteros 2 collaborations

Selvaraj Kunjiappan 2 collaborations

Joazaizulfazli Jamalis 2 collaborations

José Muñoz 2 collaborations

Rubén Carbajo-Andrés 2 collaborations

Mark Cushman 2 collaborations

Concepción Alonso 2 collaborations

Asier Selas 2 collaborations

Estela Melcón-Fernández 2 collaborations

Birgitta R Knudsen 2 collaborations

Concepcion Alonso 2 collaborations

Maria Del Camino Gutiérrez-Corbo 1 collaboration

Carmen Punzón 1 collaboration

Maria Yolanda Pérez-Pertejo 1 collaboration

Manuel Fresno 1 collaboration

Manuel Soto 1 collaboration

Laura Ramírez 1 collaboration

José Carlos Solana 1 collaboration

Emma C L Cook 1 collaboration

Elena Hernández-García 1 collaboration

Sara Charro-Zanca 1 collaboration

Ana Redondo-Urzainqui 1 collaboration

Cristina Esteban-Blanco 1 collaboration

Héctor Argüello 1 collaboration

Sonia Andrés 1 collaboration

Juan José Arranz 1 collaboration

Beatriz Gutiérrez-Gil 1 collaboration

Estela Melcon-Fernandez 1 collaboration

Vanderlan Nogueira Holanda 1 collaboration

Oskar Franch 1 collaboration

Thomas Boesen 1 collaboration

Pia Bomholt Jensen 1 collaboration

Lene N Nejsum 1 collaboration

Simon Pagaard Nielsen 1 collaboration

Prakruti R Singh 1 collaboration

Rajiv Kumar Jha 1 collaboration

Valakunja Nagaraja 1 collaboration

Yi-Ping Ho 1 collaboration

Birgitta Ruth Knudsen 1 collaboration

César Ordóñez 1 collaboration

Nestor M Carballeira 1 collaboration

Maria Martinez-Valladares 1 collaboration

Philip Skuce 1 collaboration

Alison Morrison 1 collaboration

Adinarayana Nandikolla 1 collaboration

Singireddi Srinivasarao 1 collaboration

Himanshu Aggarwal 1 collaboration

Rebeca Domínguez-Santos 1 collaboration

Katarina Kosalková 1 collaboration

Isabel-Clara Sánchez-Orejas 1 collaboration

Carlos Barreiro 1 collaboration

Cécile Häberli 1 collaboration

Jennifer Keiser 1 collaboration

María-Cristina González-Montero 1 collaboration

Julia Andrés-Rodríguez 1 collaboration

Elías Martín-Ramos 1 collaboration

Francisco Antonio Rojo-Vázquez 1 collaboration

Marta Ruiz-Somacarrera 1 collaboration

Marta González-Warleta 1 collaboration

Javier Merino-Goyenechea 1 collaboration

Jesús Palacios-Alberti 1 collaboration

Tomás Yanes-Martínez 1 collaboration

Francisco Rojo-Vázquez 1 collaboration

Ehab K Elmahallawy 1 collaboration

M Yolanda Pérez Pertejo 1 collaboration

José M Escudero-Martínez 1 collaboration

Pablo A García 1 collaboration

Pablo G Jambrina 1 collaboration

María-Ángeles Castro 1 collaboration

Ana Tejería 1 collaboration

Endika Martin-Encinas 1 collaboration

Gloria Rubiales 1 collaboration

María Fuertes 1 collaboration

Kamilla Vandsø Petersen 1 collaboration

Karol Mizielinski 1 collaboration

Celine Thiesen 1 collaboration

Lotte Bjergbæk 1 collaboration

Angela Trejo 1 collaboration

Carme Masdeu 1 collaboration

Cinzia Tesauro 1 collaboration

Leila Masoori 1 collaboration

Amal Khudair Khalaf 1 collaboration

Fatemeh Ezatkhah 1 collaboration

Hossein Mahmoudvand 1 collaboration

Laura I Vossen 1 collaboration

M Yolanda Pérez-Pertejo 1 collaboration

Marcelo Calderón 1 collaboration

Jaime Sanchis 1 collaboration

Camino González-Lanza 1 collaboration

Berta Grau-Pujol 1 collaboration

María Cambra-Pelleja 1 collaboration

Valdemiro Escola 1 collaboration

Maria Antonietta Demontis 1 collaboration

Anelsio Cossa 1 collaboration

José Carlos Jamine 1 collaboration

Lisette van Lieshout 1 collaboration

None None 1 collaboration

Felio J Bello 1 collaboration

F Javier Giráldez 1 collaboration

Raquel Vallejo García 1 collaboration

M Abirami 1 collaboration

Sanchita Dey 1 collaboration

Samridhi Johri 1 collaboration

Endika Martín-Encinas 1 collaboration

Gulio Galli 1 collaboration

María Cambra-Pellejà 1 collaboration

Jennifer Antwi-Ekwuruke 1 collaboration

Lara Linnemann 1 collaboration

Lennart Heepmann 1 collaboration

Minka Breloer 1 collaboration