Accueil
Riley E Perszyk
Riley E Perszyk
Affiliations
Department of Pharmacology and Chemical Biology, Emory University School of Medicine, Atlanta, GA, 30322, USA.
ORCID: 0000-0001-8283-7709
Publications (17)
Hodgkin-Huxley-Katz Prize Lecture: Genetic and pharmacological control of glutamate receptor channel through a highly conserved gating motif.
The Journal of physiology
Avec:
Riley E Perszyk
,
Scott J Myers
,
Hongjie Yuan
,
Alasdair J Gibb
,
Hiro Furukawa
,
Alexander I Sobolevsky
,
Stephen F Traynelis
Automated Intracellular Pharmacological Electrophysiology for Ligand-Gated Ionotropic Receptor and Pharmacology Screening.
Molecular pharmacology
Avec:
Riley E Perszyk
,
Mighten C Yip
,
Ona L McConnell
,
Eric T Wang
,
Andrew Jenkins
,
Stephen F Traynelis
,
Craig R Forest
Three-dimensional missense tolerance ratio analysis.
Genome research
Avec:
Riley E Perszyk
,
Anders S Kristensen
,
Polina Lyuboslavsky
,
Stephen F Traynelis
Clinical and functional consequences of GRIA variants in patients with neurological diseases.
Cellular and molecular life sciences : CMLS
Avec:
Wenshu XiangWei
,
Riley E Perszyk
,
Nana Liu
,
Yuchen Xu
,
Subhrajit Bhattacharya
,
Gil H Shaulsky
,
Constance Smith-Hicks
,
Ali Fatemi
,
Andrew E Fry
,
Kate Chandler
,
Tao Wang
,
Julie Vogt
,
Julie S Cohen
,
Alex R Paciorkowski
,
Annapurna Poduri
,
Yuehua Zhang
,
Shuang Wang
,
Yuping Wang
,
Qiongxiang Zhai
,
Fang Fang
,
Jie Leng
,
Kathryn Garber
,
Scott J Myers
,
Robin-Tobias Jauss
,
Kristen L Park
,
Timothy A Benke
,
Johannes R Lemke
,
Hongjie Yuan
,
Yuwu Jiang
,
Stephen F Traynelis
De novo CLPTM1 variants with reduced GABA
Epilepsia
Avec:
Nana Liu
,
Jinliang Li
,
Kai Gao
,
Riley E Perszyk
,
Jing Zhang
,
Jingmin Wang
,
Ye Wu
,
Andrew Jenkins
,
Hongjie Yuan
,
Stephen F Traynelis
,
Yuwu Jiang
De novo GRIN variants in M3 helix associated with neurological disorders control channel gating of NMDA receptor.
Cellular and molecular life sciences : CMLS
Avec:
Yuchen Xu
,
Rui Song
,
Riley E Perszyk
,
Wenjuan Chen
,
Sukhan Kim
,
Kristen L Park
,
James P Allen
,
Kelsey A Nocilla
,
Jing Zhang
,
Wenshu XiangWei
,
Anel Tankovic
,
Ellington D McDaniels
,
Rehan Sheikh
,
Ruth K Mizu
,
Manish M Karamchandani
,
Chun Hu
,
Hirofumi Kusumoto
,
Joseph Pecha
,
Gerarda Cappuccio
,
John Gaitanis
,
Jennifer Sullivan
,
Vandana Shashi
,
Slave Petrovski
,
Robin-Tobias Jauss
,
Hyun Kyung Lee
,
Xiuhua Bozarth
,
David R Lynch
,
Ingo Helbig
,
Tyler Mark Pierson
,
Cornelius F Boerkoel
,
Scott J Myers
,
Johannes R Lemke
,
Timothy A Benke
,
Hongjie Yuan
,
Stephen F Traynelis
Molecular pharmacology
Avec:
Elijah Z Ullman
,
Riley E Perszyk
,
Srinu Paladugu
,
Russell G Fritzemeier
,
Nicholas S Akins
,
Leon Jacobs
,
Dennis C Liotta
,
Stephen F Traynelis
Biased modulators of NMDA receptors control channel opening and ion selectivity.
Nature chemical biology
Avec:
Riley E Perszyk
,
Sharon A Swanger
,
Chris Shelley
,
Alpa Khatri
,
Gabriela Fernandez-Cuervo
,
Matthew P Epplin
,
Jing Zhang
,
Phuong Le
,
Pernille Bülow
,
Ethel Garnier-Amblard
,
Pavan Kumar Reddy Gangireddy
,
Gary J Bassell
,
Hongjie Yuan
,
David S Menaldino
,
Dennis C Liotta
,
Lanny S Liebeskind
,
Stephen F Traynelis
Therapeutic potential of N-methyl-D-aspartate receptor modulators in psychiatry.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Avec:
Jesse E Hanson
,
Hongjie Yuan
,
Riley E Perszyk
,
Tue G Banke
,
Hao Xing
,
Ming-Chi Tsai
,
Frank S Menniti
,
Stephen F Traynelis
Differential responses of disease-related GRIN variants located in pore-forming M2 domain of N-methyl-D-aspartate receptor to FDA-approved inhibitors.
Journal of neurochemistry
Avec:
Rui Song
,
Jin Zhang
,
Riley E Perszyk
,
Chad R Camp
,
Weiting Tang
,
Varun Kannan
,
Jia Li
,
Yuchen Xu
,
Jiahui Chen
,
Yinlong Li
,
Steven H Liang
,
Stephen F Traynelis
,
Hongjie Yuan
Structure, Function, and Pharmacology of Glutamate Receptor Ion Channels.
Pharmacological reviews
Avec:
Kasper B Hansen
,
Lonnie P Wollmuth
,
Derek Bowie
,
Hiro Furukawa
,
Frank S Menniti
,
Alexander I Sobolevsky
,
Geoffrey T Swanson
,
Sharon A Swanger
,
Ingo H Greger
,
Terunaga Nakagawa
,
Chris J McBain
,
Vasanthi Jayaraman
,
Chian-Ming Low
,
Mark L Dell'Acqua
,
Jeffrey S Diamond
,
Chad R Camp
,
Riley E Perszyk
,
Hongjie Yuan
,
Stephen F Traynelis
The Negative Allosteric Modulator EU1794-4 Reduces Single-Channel Conductance and Ca
Molecular pharmacology
Avec:
Riley E Perszyk
,
Zhaoshi Zheng
,
Tue G Banke
,
Jing Zhang
,
Lingling Xie
,
Miranda J McDaniel
,
Brooke M Katzman
,
Stephen C Pelly
,
Hongjie Yuan
,
Dennis C Liotta
,
Stephen F Traynelis
Functional Assessment of Cancer-Linked Mutations in Sensitive Regions of Regulators of G Protein Signaling Predicted by Three-Dimensional Missense Tolerance Ratio Analysis.
Molecular pharmacology
Avec:
Carolina Montañez-Miranda
,
Riley E Perszyk
,
Nicholas H Harbin
,
Jennifer Okalova
,
Suneela Ramineni
,
Stephen F Traynelis
,
John R Hepler
Functional effects of disease-associated variants reveal that the S1-M1 linker of the NMDA receptor critically controls channel opening.
Cellular and molecular life sciences : CMLS
Avec:
Lingling Xie
,
Miranda J McDaniel
,
Riley E Perszyk
,
Sukhan Kim
,
Gerarda Cappuccio
,
Kevin A Shapiro
,
Beatriz Muñoz-Cabello
,
Pedro A Sanchez-Lara
,
Katheryn Grand
,
Jing Zhang
,
Kelsey A Nocilla
,
Rehan Sheikh
,
Lluis Armengol
,
Roberta Romano
,
Tyler Mark Pierson
,
Hongjie Yuan
,
Scott J Myers
,
Stephen F Traynelis
Opportunities for Precision Treatment of
The Journal of pharmacology and experimental therapeutics
Avec:
Wei Han
,
Hongjie Yuan
,
James P Allen
,
Sukhan Kim
,
Gil H Shaulsky
,
Riley E Perszyk
,
Stephen F Traynelis
,
Scott J Myers
Classification of missense variants in the N-methyl-d-aspartate receptor GRIN gene family as gain- or loss-of-function.
Human molecular genetics
Avec:
Scott J Myers
,
Hongjie Yuan
,
Riley E Perszyk
,
Jing Zhang
,
Sukhan Kim
,
Kelsey A Nocilla
,
James P Allen
,
Jennifer M Bain
,
Johannes R Lemke
,
Dennis Lal
,
Timothy A Benke
,
Stephen F Traynelis
Development of a Dihydroquinoline-Pyrazoline GluN2C/2D-Selective Negative Allosteric Modulator of the
ACS chemical neuroscience
Avec:
Michael P D'Erasmo
,
Nicholas S Akins
,
Peipei Ma
,
Yao Jing
,
Sharon A Swanger
,
Savita K Sharma
,
Perry W Bartsch
,
David S Menaldino
,
Paul J Arcoria
,
Thi-Thien Bui
,
Alexandre Pons-Bennaceur
,
Phuong Le
,
James P Allen
,
Elijah Z Ullman
,
Kelsey A Nocilla
,
Jing Zhang
,
Riley E Perszyk
,
Sukhan Kim
,
Timothy M Acker
,
Azmain Taz
,
Samantha L Burton
,
Kevin Coe
,
Russell G Fritzemeier
,
Nail Burnashev
,
Hongjie Yuan
,
Dennis C Liotta
,
Stephen F Traynelis
Réseau de co-auteurs
Stephen F Traynelis
17 collaborations
Hongjie Yuan
13 collaborations
Jing Zhang
7 collaborations
Scott J Myers
6 collaborations
Sukhan Kim
5 collaborations
James P Allen
4 collaborations
Kelsey A Nocilla
4 collaborations
Dennis C Liotta
4 collaborations
Yuchen Xu
3 collaborations
Timothy A Benke
3 collaborations
Johannes R Lemke
3 collaborations
Sharon A Swanger
3 collaborations
Hiro Furukawa
2 collaborations
Alexander I Sobolevsky
2 collaborations
Andrew Jenkins
2 collaborations
Wenshu XiangWei
2 collaborations
Nana Liu
2 collaborations
Gil H Shaulsky
2 collaborations
Robin-Tobias Jauss
2 collaborations
Kristen L Park
2 collaborations
Yuwu Jiang
2 collaborations
Rui Song
2 collaborations
Rehan Sheikh
2 collaborations
Gerarda Cappuccio
2 collaborations
Tyler Mark Pierson
2 collaborations
Elijah Z Ullman
2 collaborations
Russell G Fritzemeier
2 collaborations
Nicholas S Akins
2 collaborations
Phuong Le
2 collaborations
David S Menaldino
2 collaborations
Tue G Banke
2 collaborations
Frank S Menniti
2 collaborations
Chad R Camp
2 collaborations
Lingling Xie
2 collaborations
Miranda J McDaniel
2 collaborations
Alasdair J Gibb
1 collaboration
Mighten C Yip
1 collaboration
Ona L McConnell
1 collaboration
Eric T Wang
1 collaboration
Craig R Forest
1 collaboration
Anders S Kristensen
1 collaboration
Polina Lyuboslavsky
1 collaboration
Subhrajit Bhattacharya
1 collaboration
Constance Smith-Hicks
1 collaboration
Ali Fatemi
1 collaboration
Andrew E Fry
1 collaboration
Kate Chandler
1 collaboration
Tao Wang
1 collaboration
Julie Vogt
1 collaboration
Julie S Cohen
1 collaboration
Alex R Paciorkowski
1 collaboration
Annapurna Poduri
1 collaboration
Yuehua Zhang
1 collaboration
Shuang Wang
1 collaboration
Yuping Wang
1 collaboration
Qiongxiang Zhai
1 collaboration
Fang Fang
1 collaboration
Jie Leng
1 collaboration
Kathryn Garber
1 collaboration
Jinliang Li
1 collaboration
Kai Gao
1 collaboration
Jingmin Wang
1 collaboration
Ye Wu
1 collaboration
Wenjuan Chen
1 collaboration
Anel Tankovic
1 collaboration
Ellington D McDaniels
1 collaboration
Ruth K Mizu
1 collaboration
Manish M Karamchandani
1 collaboration
Chun Hu
1 collaboration
Hirofumi Kusumoto
1 collaboration
Joseph Pecha
1 collaboration
John Gaitanis
1 collaboration
Jennifer Sullivan
1 collaboration
Vandana Shashi
1 collaboration
Slave Petrovski
1 collaboration
Hyun Kyung Lee
1 collaboration
Xiuhua Bozarth
1 collaboration
David R Lynch
1 collaboration
Ingo Helbig
1 collaboration
Cornelius F Boerkoel
1 collaboration
Srinu Paladugu
1 collaboration
Leon Jacobs
1 collaboration
Chris Shelley
1 collaboration
Alpa Khatri
1 collaboration
Gabriela Fernandez-Cuervo
1 collaboration
Matthew P Epplin
1 collaboration
Pernille Bülow
1 collaboration
Ethel Garnier-Amblard
1 collaboration
Pavan Kumar Reddy Gangireddy
1 collaboration
Gary J Bassell
1 collaboration
Lanny S Liebeskind
1 collaboration
Jesse E Hanson
1 collaboration
Hao Xing
1 collaboration
Ming-Chi Tsai
1 collaboration
Jin Zhang
1 collaboration
Weiting Tang
1 collaboration
Varun Kannan
1 collaboration
Jia Li
1 collaboration
Jiahui Chen
1 collaboration
Yinlong Li
1 collaboration
Steven H Liang
1 collaboration
Kasper B Hansen
1 collaboration
Lonnie P Wollmuth
1 collaboration
Derek Bowie
1 collaboration
Geoffrey T Swanson
1 collaboration
Ingo H Greger
1 collaboration
Terunaga Nakagawa
1 collaboration
Chris J McBain
1 collaboration
Vasanthi Jayaraman
1 collaboration
Chian-Ming Low
1 collaboration
Mark L Dell'Acqua
1 collaboration
Jeffrey S Diamond
1 collaboration
Zhaoshi Zheng
1 collaboration
Brooke M Katzman
1 collaboration
Stephen C Pelly
1 collaboration
Carolina Montañez-Miranda
1 collaboration
Nicholas H Harbin
1 collaboration
Jennifer Okalova
1 collaboration
Suneela Ramineni
1 collaboration
John R Hepler
1 collaboration
Kevin A Shapiro
1 collaboration
Beatriz Muñoz-Cabello
1 collaboration
Pedro A Sanchez-Lara
1 collaboration
Katheryn Grand
1 collaboration
Lluis Armengol
1 collaboration
Roberta Romano
1 collaboration
Wei Han
1 collaboration
Jennifer M Bain
1 collaboration
Dennis Lal
1 collaboration
Michael P D'Erasmo
1 collaboration
Peipei Ma
1 collaboration
Yao Jing
1 collaboration
Savita K Sharma
1 collaboration
Perry W Bartsch
1 collaboration
Paul J Arcoria
1 collaboration
Thi-Thien Bui
1 collaboration
Alexandre Pons-Bennaceur
1 collaboration
Timothy M Acker
1 collaboration
Azmain Taz
1 collaboration
Samantha L Burton
1 collaboration
Kevin Coe
1 collaboration
Nail Burnashev
1 collaboration