Robert Ballotti

Affiliations

Team 1, Université Côte d'Azur, INSERM U1065, Centre Méditerranéen de Médecine Moléculaire (C3M), Nice, 06200, France.

Publications (22)

Innate lymphocyte-induced CXCR3B-mediated melanocyte apoptosis is a potential initiator of T-cell autoreactivity in vitiligo.

Nature communications

Avec: Meri K Tulic , Elisa Cavazza , Yann Cheli , Arnaud Jacquel , Carmelo Luci , Nathalie Cardot-Leccia , Hanene Hadhiri-Bzioueche , Patricia Abbe , Maéva Gesson , Laura Sormani , Claire Regazzetti , Guillaume E Beranger , Cedric Lereverend , Caroline Pons , Abdallah Khemis , Robert Ballotti , Corine Bertolotto , Stéphane Rocchi , Thierry Passeron

Regulation of Melanogenesis by the Amino Acid Transporter SLC7A5.

The Journal of investigative dermatology

Avec: Céline Gaudel , Frédéric Soysouvanh , Justine Leclerc , Karine Bille , Chrystel Husser , François Montcriol , Corine Bertolotto , Robert Ballotti

Endoplasmic reticulum stress mediates resistance to BCL-2 inhibitor in uveal melanoma cells.

Cell death discovery

Avec: Lara Bellini , Thomas Strub , Nadia Habel , Charlotte Pandiani , Sandrine Marchetti , Arnaud Martel , Stéphanie Baillif , Béatrice Bailly-Maitre , Philippe Gual , Robert Ballotti , Corine Bertolotto

Microphthalmia-Associated Transcription Factor (MITF) Regulates Immune Cell Migration into Melanoma.

Translational oncology

Avec: Gabriela M Wiedemann , Celina Aithal , Angelina Kraechan , Constanze Heise , Bruno L Cadilha , Jin Zhang , Peter Duewell , Robert Ballotti , Stefan Endres , Corine Bertolotto , Sebastian Kobold

Single-cell RNA sequencing reveals intratumoral heterogeneity in primary uveal melanomas and identifies HES6 as a driver of the metastatic disease.

Cell death and differentiation

Avec: Charlotte Pandiani , Thomas Strub , Nicolas Nottet , Yann Cheli , Giovanni Gambi , Karine Bille , Chrystel Husser , Mélanie Dalmasso , Guillaume Béranger , Sandra Lassalle , Virginie Magnone , Florence Pédeutour , Marie Irondelle , Célia Maschi , Sacha Nahon-Estève , Arnaud Martel , Jean-Pierre Caujolle , Paul Hofman , Kévin LeBrigand , Irwin Davidson , Stéphanie Baillif , Pascal Barbry , Robert Ballotti , Corine Bertolotto

Immune Checkpoints in Cancers: From Signaling to the Clinic.

Cancers

Avec: Céline Pisibon , Amira Ouertani , Corine Bertolotto , Robert Ballotti , Yann Cheli

Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses.

Cell reports

Avec: Thomas Botton , Eric Talevich , Vivek Kumar Mishra , Tongwu Zhang , A Hunter Shain , Céline Berquet , Alexander Gagnon , Robert L Judson , Robert Ballotti , Antoni Ribas , Meenhard Herlyn , Stéphane Rocchi , Kevin M Brown , Nicholas K Hayward , Iwei Yeh , Boris C Bastian

The "ART" of Epigenetics in Melanoma: From histone "Alterations, to Resistance and Therapies".

Theranostics

Avec: Thomas Strub , Robert Ballotti , Corine Bertolotto

An Update on the Role of Ubiquitination in Melanoma Development and Therapies.

Journal of clinical medicine

Avec: Frédéric Soysouvanh , Serena Giuliano , Nadia Habel , Najla El-Hachem , Céline Pisibon , Corine Bertolotto , Robert Ballotti

Discovery of a new molecule inducing melanoma cell death: dual AMPK/MELK targeting for novel melanoma therapies.

Cell death & disease

Avec: Emilie Jaune , Elisa Cavazza , Cyril Ronco , Oleksandr Grytsai , Patricia Abbe , Nedra Tekaya , Marwa Zerhouni , Guillaume Beranger , Lisa Kaminski , Frédéric Bost , Maeva Gesson , Meri Tulic , Paul Hofman , Robert Ballotti , Thierry Passeron , Thomas Botton , Rachid Benhida , Stéphane Rocchi

Methiothepin Increases Chemotherapy Efficacy against Resistant Melanoma Cells.

Molecules (Basel, Switzerland)

Avec: Nelly Durand , Méliné Simsir , Laurie Signetti , Fabien Labbal , Robert Ballotti , Isabelle Mus-Veteau

FBXO32 links ubiquitination to epigenetic reprograming of melanoma cells.

Cell death and differentiation

Avec: Nadia Habel , Najla El-Hachem , Frédéric Soysouvanh , Hanene Hadhiri-Bzioueche , Serena Giuliano , Sophie Nguyen , Pavel Horák , Anne-Sophie Gay , Delphine Debayle , Nicolas Nottet , Guillaume Béranger , Brigitte Bressac-de Paillerets , Corine Bertolotto , Robert Ballotti

Lysine Methyltransferase NSD1 and Cancers: Any Role in Melanoma?

Cancers

Avec: Imène Krossa , Thomas Strub , Andrew E Aplin , Robert Ballotti , Corine Bertolotto

LKB1-SIK2 loss drives uveal melanoma proliferation and hypersensitivity to SLC8A1 and ROS inhibition.

EMBO molecular medicine

Avec: Sarah Proteau , Imène Krossa , Chrystel Husser , Maxime Guéguinou , Federica Sella , Karine Bille , Marie Irondelle , Mélanie Dalmasso , Thibault Barouillet , Yann Cheli , Céline Pisibon , Nicole Arrighi , Sacha Nahon-Estève , Arnaud Martel , Lauris Gastaud , Sandra Lassalle , Olivier Mignen , Patrick Brest , Nathalie M Mazure , Frédéric Bost , Stéphanie Baillif , Solange Landreville , Simon Turcotte , Dan Hasson , Saul Carcamo , Christophe Vandier , Emily Bernstein , Laurent Yvan-Charvet , Mitchell P Levesque , Robert Ballotti , Corine Bertolotto , Thomas Strub

AMBRA1 levels predict resistance to MAPK inhibitors in melanoma.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Luca Di Leo , Chiara Pagliuca , Ali Kishk , Salvatore Rizza , Christina Tsiavou , Chiara Pecorari , Christina Dahl , Maria Pires Pacheco , Rikke Tholstrup , Jonathan Richard Brewer , Pietro Berico , Eva Hernando , Francesco Cecconi , Robert Ballotti , Corine Bertolotto , Giuseppe Filomeni , Morten Frier Gjerstorff , Thomas Sauter , Penny Lovat , Per Guldberg , Daniela De Zio

HVEM has a broader expression than PD-L1 and constitutes a negative prognostic marker and potential treatment target for melanoma.

Oncoimmunology

Avec: Nausicaa Malissen , Nicolas Macagno , Samuel Granjeaud , Clémence Granier , Vincent Moutardier , Caroline Gaudy-Marqueste , Nadia Habel , Marion Mandavit , Bernard Guillot , Christine Pasero , Eric Tartour , Robert Ballotti , Jean-Jacques Grob , Daniel Olive

Lysosomal acid ceramidase ASAH1 controls the transition between invasive and proliferative phenotype in melanoma cells.

Oncogene

Avec: Justine Leclerc , David Garandeau , Charlotte Pandiani , Céline Gaudel , Karine Bille , Nicolas Nottet , Virginie Garcia , Pascal Colosetti , Sophie Pagnotta , Philippe Bahadoran , Garance Tondeur , Baharia Mograbi , Stéphane Dalle , Julie Caramel , Thierry Levade , Robert Ballotti , Nathalie Andrieu-Abadie , Corine Bertolotto

Germline variants in exonic regions have limited impact on immune checkpoint blockade clinical outcomes in advanced melanoma.

Pigment cell & melanoma research

Avec: Henri Montaudié , Guillaume Emmanuel Beranger , Frédéric Reinier , Nicolas Nottet , Hélène Martin , Alexandra Picard-Gauci , Laura Troin , Robert Ballotti , Thierry Passeron

Translation of single-cell transcriptomic analysis of uveal melanomas to clinical oncology.

Progress in retinal and eye research

Avec: Thomas Strub , Arnaud Martel , Sacha Nahon-Esteve , Stéphanie Baillif , Robert Ballotti , Corine Bertolotto

ITGBL1 is a new immunomodulator that favors development of melanoma tumors by inhibiting natural killer cells cytotoxicity.

Molecular cancer

Avec: Yann Cheli , Meri K Tulic , Najla El Hachem , Nicolas Nottet , Arnaud Jacquel , Maeva Gesson , Thomas Strub , Karine Bille , Alexandra Picard-Gauci , Henri Montaudié , Guillaume E Beranger , Thierry Passeron , Pierre Close , Corine Bertolotto , Robert Ballotti

The complex relationship between MITF and the immune system: a Melanoma ImmunoTherapy (response) Factor?

Molecular cancer

Avec: Robert Ballotti , Yann Cheli , Corine Bertolotto

Recent advances in understanding the role of HES6 in cancers.

Theranostics

Avec: Imène Krossa , Thomas Strub , Arnaud Martel , Sacha Nahon-Esteve , Sandra Lassalle , Paul Hofman , Stéphanie Baillif , Robert Ballotti , Corine Bertolotto

Réseau de co-auteurs

Corine Bertolotto 17 collaborations

Thomas Strub 8 collaborations

Yann Cheli 6 collaborations

Karine Bille 5 collaborations

Arnaud Martel 5 collaborations

Stéphanie Baillif 5 collaborations

Nicolas Nottet 5 collaborations

Thierry Passeron 4 collaborations

Nadia Habel 4 collaborations

Stéphane Rocchi 3 collaborations

Frédéric Soysouvanh 3 collaborations

Chrystel Husser 3 collaborations

Charlotte Pandiani 3 collaborations

Sandra Lassalle 3 collaborations

Paul Hofman 3 collaborations

Céline Pisibon 3 collaborations

Imène Krossa 3 collaborations

Meri K Tulic 2 collaborations

Elisa Cavazza 2 collaborations

Arnaud Jacquel 2 collaborations

Hanene Hadhiri-Bzioueche 2 collaborations

Patricia Abbe 2 collaborations

Guillaume E Beranger 2 collaborations

Céline Gaudel 2 collaborations

Justine Leclerc 2 collaborations

Mélanie Dalmasso 2 collaborations

Guillaume Béranger 2 collaborations

Marie Irondelle 2 collaborations

Sacha Nahon-Estève 2 collaborations

Thomas Botton 2 collaborations

Serena Giuliano 2 collaborations

Najla El-Hachem 2 collaborations

Frédéric Bost 2 collaborations

Maeva Gesson 2 collaborations

Henri Montaudié 2 collaborations

Alexandra Picard-Gauci 2 collaborations

Sacha Nahon-Esteve 2 collaborations

Carmelo Luci 1 collaboration

Nathalie Cardot-Leccia 1 collaboration

Maéva Gesson 1 collaboration

Laura Sormani 1 collaboration

Claire Regazzetti 1 collaboration

Cedric Lereverend 1 collaboration

Caroline Pons 1 collaboration

Abdallah Khemis 1 collaboration

François Montcriol 1 collaboration

Lara Bellini 1 collaboration

Sandrine Marchetti 1 collaboration

Béatrice Bailly-Maitre 1 collaboration

Philippe Gual 1 collaboration

Gabriela M Wiedemann 1 collaboration

Celina Aithal 1 collaboration

Angelina Kraechan 1 collaboration

Constanze Heise 1 collaboration

Bruno L Cadilha 1 collaboration

Jin Zhang 1 collaboration

Peter Duewell 1 collaboration

Stefan Endres 1 collaboration

Sebastian Kobold 1 collaboration

Giovanni Gambi 1 collaboration

Virginie Magnone 1 collaboration

Florence Pédeutour 1 collaboration

Célia Maschi 1 collaboration

Jean-Pierre Caujolle 1 collaboration

Kévin LeBrigand 1 collaboration

Irwin Davidson 1 collaboration

Pascal Barbry 1 collaboration

Amira Ouertani 1 collaboration

Eric Talevich 1 collaboration

Vivek Kumar Mishra 1 collaboration

Tongwu Zhang 1 collaboration

A Hunter Shain 1 collaboration

Céline Berquet 1 collaboration

Alexander Gagnon 1 collaboration

Robert L Judson 1 collaboration

Antoni Ribas 1 collaboration

Meenhard Herlyn 1 collaboration

Kevin M Brown 1 collaboration

Nicholas K Hayward 1 collaboration

Iwei Yeh 1 collaboration

Boris C Bastian 1 collaboration

Emilie Jaune 1 collaboration

Cyril Ronco 1 collaboration

Oleksandr Grytsai 1 collaboration

Nedra Tekaya 1 collaboration

Marwa Zerhouni 1 collaboration

Guillaume Beranger 1 collaboration

Lisa Kaminski 1 collaboration

Meri Tulic 1 collaboration

Rachid Benhida 1 collaboration

Nelly Durand 1 collaboration

Méliné Simsir 1 collaboration

Laurie Signetti 1 collaboration

Fabien Labbal 1 collaboration

Isabelle Mus-Veteau 1 collaboration

Sophie Nguyen 1 collaboration

Pavel Horák 1 collaboration

Anne-Sophie Gay 1 collaboration

Delphine Debayle 1 collaboration

Brigitte Bressac-de Paillerets 1 collaboration

Andrew E Aplin 1 collaboration

Sarah Proteau 1 collaboration

Maxime Guéguinou 1 collaboration

Federica Sella 1 collaboration

Thibault Barouillet 1 collaboration

Nicole Arrighi 1 collaboration

Lauris Gastaud 1 collaboration

Olivier Mignen 1 collaboration

Patrick Brest 1 collaboration

Nathalie M Mazure 1 collaboration

Solange Landreville 1 collaboration

Simon Turcotte 1 collaboration

Dan Hasson 1 collaboration

Saul Carcamo 1 collaboration

Christophe Vandier 1 collaboration

Emily Bernstein 1 collaboration

Laurent Yvan-Charvet 1 collaboration

Mitchell P Levesque 1 collaboration

Luca Di Leo 1 collaboration

Chiara Pagliuca 1 collaboration

Ali Kishk 1 collaboration

Salvatore Rizza 1 collaboration

Christina Tsiavou 1 collaboration

Chiara Pecorari 1 collaboration

Christina Dahl 1 collaboration

Maria Pires Pacheco 1 collaboration

Rikke Tholstrup 1 collaboration

Jonathan Richard Brewer 1 collaboration

Pietro Berico 1 collaboration

Eva Hernando 1 collaboration

Francesco Cecconi 1 collaboration

Giuseppe Filomeni 1 collaboration

Morten Frier Gjerstorff 1 collaboration

Thomas Sauter 1 collaboration

Penny Lovat 1 collaboration

Per Guldberg 1 collaboration

Daniela De Zio 1 collaboration

Nausicaa Malissen 1 collaboration

Nicolas Macagno 1 collaboration

Samuel Granjeaud 1 collaboration

Clémence Granier 1 collaboration

Vincent Moutardier 1 collaboration

Caroline Gaudy-Marqueste 1 collaboration

Marion Mandavit 1 collaboration

Bernard Guillot 1 collaboration

Christine Pasero 1 collaboration

Eric Tartour 1 collaboration

Jean-Jacques Grob 1 collaboration

Daniel Olive 1 collaboration

David Garandeau 1 collaboration

Virginie Garcia 1 collaboration

Pascal Colosetti 1 collaboration

Sophie Pagnotta 1 collaboration

Philippe Bahadoran 1 collaboration

Garance Tondeur 1 collaboration

Baharia Mograbi 1 collaboration

Stéphane Dalle 1 collaboration

Julie Caramel 1 collaboration

Thierry Levade 1 collaboration

Nathalie Andrieu-Abadie 1 collaboration

Guillaume Emmanuel Beranger 1 collaboration

Frédéric Reinier 1 collaboration

Hélène Martin 1 collaboration

Laura Troin 1 collaboration

Najla El Hachem 1 collaboration

Pierre Close 1 collaboration