Robert Croop

Affiliations

Biohaven Pharmaceuticals, New Haven, CT, USA.

Publications (30)

Safety of Rimegepant in Patients Using Preventive Migraine Medications: A Subgroup Analysis of a Long-Term, Open-Label Study Conducted in the United States.

Journal of pain research

Avec: Gary Berman , Alexandra Thiry , Robert Croop

Rimegepant, Ubrogepant, and Lasmiditan in the Acute Treatment of Migraine Examining the Benefit-Risk Profile Using Number Needed to Treat/Harm.

The Clinical journal of pain

Avec: Karissa M Johnston , Lauren Powell , Evan Popoff , Linda Harris , Robert Croop , Vladimir Coric , Gilbert L'Italien

Safety, tolerability, and efficacy of zavegepant 10 mg nasal spray for the acute treatment of migraine in the USA: a phase 3, double-blind, randomised, placebo-controlled multicentre trial.

The Lancet. Neurology

Avec: Richard B Lipton , Robert Croop , David A Stock , Jennifer Madonia , Micaela Forshaw , Meghan Lovegren , Linda Mosher , Vladimir Coric , Peter J Goadsby

A placebo-controlled, randomized, single and multiple dose study to evaluate the safety, tolerability, and pharmacokinetics of rimegepant in healthy participants.

Cephalalgia : an international journal of headache

Avec: Richard Bertz , Rajinder Bhardwaj , Beth A Morris , Eric Ashbrenner , Vladimir Coric , Robert Croop

The Pharmacokinetics, Safety, and Tolerability of Rimegepant 75 mg Are Similar in Elderly and Nonelderly Adults: A Phase 1, Open-Label, Parallel-Group, Single-Dose Study.

Clinical pharmacology in drug development

Avec: Rajinder Bhardwaj , Beth Morris , Richard Bertz , Robert Croop , Jing Liu

Bioequivalence of rimegepant, a small molecule CGRP receptor antagonist, administered as an oral tablet, a sublingual orally disintegrating tablet, and a supralingual orally disintegrating tablet: two phase 1 randomized studies in healthy adults.

Cephalalgia : an international journal of headache

Avec: Robert Croop , Rajinder Bhardwaj , Matt S Anderson , Kyle T Matschke , Jennifer Hould , Richard Bertz , Jing Liu , Richard B Lipton

Rimegepant orally disintegrating tablet 75 mg for acute treatment of migraine in adults from China: a subgroup analysis of a double-blind, randomized, placebo-controlled, phase 3 clinical trial.

The journal of headache and pain

Avec: Shengyuan Yu , Aihong Guo , Zhen Wang , Jianguang Liu , Ge Tan , Qian Yang , Mingjie Zhang , Hasiyeti Yibulaiyin , Huisheng Chen , Yongbo Zhang , Robert Croop , Yanhui Sun , Yu Liu , Qian Zhao , Zhihong Lu

Potential for treatment benefit of small molecule CGRP receptor antagonist plus monoclonal antibody in migraine therapy.

Neurology

Avec: Kathleen Mullin , David Kudrow , Robert Croop , Meghan Lovegren , Charles M Conway , Vladimir Coric , Richard B Lipton

Reduced hepatic impairment study to evaluate pharmacokinetics and safety of zavegepant and to inform dosing recommendation for hepatic impairment.

Clinical and translational science

Avec: Rajinder Bhardwaj , Mary K Donohue , Jennifer Madonia , Beth Morris , Thomas C Marbury , Kyle T Matschke , Robert Croop , Richard Bertz , Jing Liu

Safety of Rimegepant, an Oral CGRP Receptor Antagonist, Plus CGRP Monoclonal Antibodies for Migraine.

Headache

Avec: Gary Berman , Robert Croop , David Kudrow , Philip Halverson , Meghan Lovegren , Alexandra C Thiry , Charles M Conway , Vladimir Coric , Richard B Lipton

Efficacy, safety, and tolerability of rimegepant orally disintegrating tablet for the acute treatment of migraine: a randomised, phase 3, double-blind, placebo-controlled trial.

Lancet (London, England)

Avec: Robert Croop , Peter J Goadsby , David A Stock , Charles M Conway , Micaela Forshaw , Elyse G Stock , Vladimir Coric , Richard B Lipton

Comparative efficacy and safety of rimegepant, ubrogepant, and lasmiditan for acute treatment of migraine: a network meta-analysis.

Expert review of pharmacoeconomics & outcomes research

Avec: Karissa Johnston , Evan Popoff , Alison Deighton , Parisa Dabirvaziri , Linda Harris , Alexandra Thiry , Robert Croop , Vladimir Coric , Gilbert L'Italien , James Moren

Rimegepant 75 mg in Subjects With Hepatic Impairment: Results of a Phase 1, Open-Label, Single-Dose, Parallel-Group Study.

Clinical pharmacology in drug development

Avec: Rajinder Bhardwaj , Andrea Ivans , Joseph Stringfellow , Beth Morris , Vladimir Coric , Robert Croop , Richard Bertz

A Drug-Drug Interaction Study to Evaluate the Impact of Rimegepant on OCT2- and MATE1-Mediated Transport of Metformin in Healthy Participants.

Clinical pharmacology in drug development

Avec: Rajinder Bhardwaj , Beth Morris , Kyle Matschke , Richard Bertz , Robert Croop , Jing Liu

Efficacy and Safety of Rimegepant 75 mg Oral Tablet, a CGRP Receptor Antagonist, for the Acute Treatment of Migraine: A Randomized, Double-Blind, Placebo-Controlled Trial.

Journal of pain research

Avec: Richard B Lipton , Alexandra Thiry , Beth A Morris , Robert Croop

Mapping Migraine-Specific Quality of Life to Health State Utilities in Patients Receiving Rimegepant.

Advances in therapy

Avec: Karissa M Johnston , Gilbert L'Italien , Evan Popoff , Lauren Powell , Robert Croop , Alexandra Thiry , Linda Harris , Vladimir Coric , Richard B Lipton

P-Glycoprotein and Breast Cancer Resistance Protein Transporter Inhibition by Cyclosporine and Quinidine on the Pharmacokinetics of Oral Rimegepant in Healthy Subjects.

Clinical pharmacology in drug development

Avec: Rajinder Bhardwaj , Julie L Collins , Joseph Stringfellow , Jennifer Madonia , Matt S Anderson , Jeri-Anne Finley , David A Stock , Vladimir Coric , Robert Croop , Richard Bertz

Zavegepant nasal spray for the acute treatment of migraine: A Phase 2/3 double-blind, randomized, placebo-controlled, dose-ranging trial.

Headache

Avec: Robert Croop , Jennifer Madonia , David A Stock , Alexandra Thiry , Micaela Forshaw , Abigail Murphy , Vladimir Coric , Richard B Lipton

Safety and efficacy of rimegepant orally disintegrating tablet for the acute treatment of migraine in China and South Korea: a phase 3, double-blind, randomised, placebo-controlled trial.

The Lancet. Neurology

Avec: Shengyuan Yu , Byung-Kun Kim , Aihong Guo , Man-Ho Kim , Mingjie Zhang , Zhen Wang , Jianguang Liu , Heui-Soo Moon , Ge Tan , Qian Yang , Donnie McGrath , Michael Hanna , David A Stock , Yanfei Gao , Robert Croop , Zhihong Lu

A multicenter, open-label long-term safety study of rimegepant for the acute treatment of migraine.

Cephalalgia : an international journal of headache

Avec: Robert Croop , Gary Berman , David Kudrow , Kathleen Mullin , Alexandra Thiry , Meghan Lovegren , Gilbert L'Italien , Richard B Lipton

Mass balance and pharmacokinetic characterization of zavegepant in healthy male subjects.

Clinical and translational science

Avec: Rajinder Bhardwaj , Mary Donohue , Jennifer Madonia , Matt S Anderson , Kyle Matschke , Richard Bertz , Robert Croop , Jing Liu

Characterization of rimegepant drug-drug interactions using the cytochrome P450 probe drugs, itraconazole, rifampin, fluconazole, and midazolam.

Headache

Avec: Rajinder Bhardwaj , Beth Morris , Kyle T Matschke , Richard Bertz , Robert Croop , Jing Liu

Assessment of pharmacokinetic and pharmacodynamic interactions between zavegepant and sumatriptan: A phase 1, randomized, placebo-controlled study in healthy adults.

Headache

Avec: Rajinder Bhardwaj , Mary K Donohue , Jennifer Madonia , Kyle Matschke , Matt S Anderson , Beth Morris , Richard Bertz , Robert Croop , Jing Liu

Rimegepant, an Oral Calcitonin Gene-Related Peptide Receptor Antagonist, for Migraine.

The New England journal of medicine

Avec: Richard B Lipton , Robert Croop , Elyse G Stock , David A Stock , Beth A Morris , Marianne Frost , Gene M Dubowchik , Charles M Conway , Vladimir Coric , Peter J Goadsby

Oral rimegepant for preventive treatment of migraine: a phase 2/3, randomised, double-blind, placebo-controlled trial.

Lancet (London, England)

Avec: Robert Croop , Richard B Lipton , David Kudrow , David A Stock , Lisa Kamen , Charles M Conway , Elyse G Stock , Vladimir Coric , Peter J Goadsby

Matching-adjusted indirect comparisons of oral rimegepant versus placebo, erenumab, and galcanezumab examining monthly migraine days and health-related quality of life in the treatment of migraine.

Headache

Avec: Evan Popoff , Karissa Johnston , Robert Croop , Alexandra Thiry , Linda Harris , Lauren Powell , Vladimir Coric , Gilbert L'Italien , James Moren

Health State Utility Mapping of Rimegepant for the Preventive Treatment of Migraine: Double-Blind Treatment Phase and Open Label Extension (BHV3000-305).

Advances in therapy

Avec: Lauren C Powell , Gilbert L'Italien , Evan Popoff , Karissa Johnston , Fiona O'Sullivan , Linda Harris , Robert Croop , Vladimir Coric , Richard B Lipton

Efficacy of rimegepant for the acute treatment of migraine based on triptan treatment experience: Pooled results from three phase 3 randomized clinical trials.

Cephalalgia : an international journal of headache

Avec: Richard B Lipton , Andrew Blumenfeld , Christopher M Jensen , Robert Croop , Alexandra Thiry , Gilbert L'Italien , Beth A Morris , Vladimir Coric , Peter J Goadsby

Long-term safety of zavegepant nasal spray for the acute treatment of migraine: A phase 2/3 open-label study.

Cephalalgia : an international journal of headache

Avec: Kathleen Mullin , Robert Croop , Linda Mosher , Terence Fullerton , Jennifer Madonia , Richard B Lipton

Safety of Rimegepant in Adults with Migraine and Cardiovascular Risk Factors: Analysis of a Multicenter, Long-Term, Open-Label Study.

Pain and therapy

Avec: David True , Kathleen Mullin , Robert Croop

Réseau de co-auteurs

Vladimir Coric 16 collaborations

Richard B Lipton 14 collaborations

Richard Bertz 10 collaborations

Rajinder Bhardwaj 10 collaborations

Alexandra Thiry 8 collaborations

Gilbert L'Italien 7 collaborations

David A Stock 7 collaborations

Jennifer Madonia 7 collaborations

Jing Liu 7 collaborations

Beth Morris 6 collaborations

Evan Popoff 5 collaborations

Linda Harris 5 collaborations

Peter J Goadsby 5 collaborations

Charles M Conway 5 collaborations

Meghan Lovegren 4 collaborations

Beth A Morris 4 collaborations

Matt S Anderson 4 collaborations

Kathleen Mullin 4 collaborations

David Kudrow 4 collaborations

Gary Berman 3 collaborations

Lauren Powell 3 collaborations

Micaela Forshaw 3 collaborations

Kyle T Matschke 3 collaborations

Elyse G Stock 3 collaborations

Karissa Johnston 3 collaborations

Kyle Matschke 3 collaborations

Karissa M Johnston 2 collaborations

Linda Mosher 2 collaborations

Shengyuan Yu 2 collaborations

Aihong Guo 2 collaborations

Zhen Wang 2 collaborations

Jianguang Liu 2 collaborations

Ge Tan 2 collaborations

Qian Yang 2 collaborations

Mingjie Zhang 2 collaborations

Zhihong Lu 2 collaborations

Mary K Donohue 2 collaborations

James Moren 2 collaborations

Joseph Stringfellow 2 collaborations

Eric Ashbrenner 1 collaboration

Jennifer Hould 1 collaboration

Hasiyeti Yibulaiyin 1 collaboration

Huisheng Chen 1 collaboration

Yongbo Zhang 1 collaboration

Yanhui Sun 1 collaboration

Yu Liu 1 collaboration

Qian Zhao 1 collaboration

Thomas C Marbury 1 collaboration

Philip Halverson 1 collaboration

Alexandra C Thiry 1 collaboration

Alison Deighton 1 collaboration

Parisa Dabirvaziri 1 collaboration

Andrea Ivans 1 collaboration

Julie L Collins 1 collaboration

Jeri-Anne Finley 1 collaboration

Abigail Murphy 1 collaboration

Byung-Kun Kim 1 collaboration

Man-Ho Kim 1 collaboration

Heui-Soo Moon 1 collaboration

Donnie McGrath 1 collaboration

Michael Hanna 1 collaboration

Yanfei Gao 1 collaboration

Mary Donohue 1 collaboration

Marianne Frost 1 collaboration

Gene M Dubowchik 1 collaboration

Lisa Kamen 1 collaboration

Lauren C Powell 1 collaboration

Fiona O'Sullivan 1 collaboration

Andrew Blumenfeld 1 collaboration

Christopher M Jensen 1 collaboration

Terence Fullerton 1 collaboration

David True 1 collaboration