Sacha J Pidot

Affiliations

Department of Microbiology and Immunology at the Doherty Institute, University of Melbourne, Melbourne, Australia.

ORCID: 0000-0003-1202-6614

Publications (34)

In vitro activity of SPR719 against Mycobacterium ulcerans, Mycobacterium marinum and Mycobacterium chimaera.

PLoS neglected tropical diseases

Avec: Sacha J Pidot , Jessica L Porter , Troy Lister , Timothy P Stinear

Marine sponge microbe provides insights into evolution and virulence of the tubercle bacillus.

PLoS pathogens

Avec: Sacha J Pidot , Stephan Klatt , Louis S Ates , Wafa Frigui , Fadel Sayes , Laleh Majlessi , Hiroshi Izumi , Ian R Monk , Jessica L Porter , Vicki Bennett-Wood , Torsten Seemann , Ashley Otter , George Taiaroa , Gregory M Cook , Nicholas West , Nicholas J Tobias , John A Fuerst , Michael D Stutz , Marc Pellegrini , Malcolm McConville , Roland Brosch , Timothy P Stinear

The Nargenicin Family of Oxa-Bridged Macrolide Antibiotics.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Sacha J Pidot , Mark A Rizzacasa

Predicting nitroimidazole antibiotic resistance mutations in Mycobacterium tuberculosis with protein engineering.

PLoS pathogens

Avec: Brendon M Lee , Liam K Harold , Deepak V Almeida , Livnat Afriat-Jurnou , Htin Lin Aung , Brian M Forde , Kiel Hards , Sacha J Pidot , F Hafna Ahmed , A Elaaf Mohamed , Matthew C Taylor , Nicholas P West , Timothy P Stinear , Chris Greening , Scott A Beatson , Eric L Nuermberger , Gregory M Cook , Colin J Jackson

Natural product discovery through microbial genome mining.

Current opinion in chemical biology

Avec: Emma Kenshole , Marion Herisse , Michael Michael , Sacha J Pidot

Widespread Family of NAD

Journal of the American Chemical Society

Avec: Arashdeep Kaur , Isabelle B Pickles , Mahima Sharma , Niccolay Madeido Soler , Nichollas E Scott , Sacha J Pidot , Ethan D Goddard-Borger , Gideon J Davies , Spencer J Williams

High antibody titres induced by protein subunit vaccines using

PeerJ

Avec: Kirstie M Mangas , Nicholas J Tobias , Estelle Marion , Jérémie Babonneau , Laurent Marsollier , Jessica L Porter , Sacha J Pidot , Chinn Yi Wong , David C Jackson , Brendon Y Chua , Timothy P Stinear

Genome Mining Reveals Endopyrroles from a Nonribosomal Peptide Assembly Line Triggered in Fungal-Bacterial Symbiosis.

ACS chemical biology

Avec: Sarah P Niehs , Benjamin Dose , Kirstin Scherlach , Sacha J Pidot , Timothy P Stinear , Christian Hertweck

Accessible Platform for High-Throughput COVID-19 Molecular Diagnostics and Genome Sequencing Using a Repurposed 3D Printer for RNA Extraction.

ACS biomaterials science & engineering

Avec: Koen Vandelannoote , Andrew H Buultjens , Lucy Li , Liam K Sharkey , Marion Herisse , Sacha J Pidot , Tuyet Hoang , Benjamin P Howden , Ian R Monk , Torsten Seemann , Jean Y H Lee , Timothy P Stinear

Draft genomes, phylogenomic reconstruction and comparative genome analysis of three

Access microbiology

Avec: Ryan Musumba Awori , Charles N Waturu , Sacha J Pidot , Nelson O Amugune , Helge B Bode

Analysis of Rhizonin Biosynthesis Reveals Origin of Pharmacophoric Furylalanine Moieties in Diverse Cyclopeptides.

Angewandte Chemie (International ed. in English)

Avec: Friedrich J Ehinger , Sarah P Niehs , Benjamin Dose , Maria Dell , Jana Krabbe , Sacha J Pidot , Timothy P Stinear , Kirstin Scherlach , Claudia Ross , Gerald Lackner , Christian Hertweck

A highly conserved gene locus in endofungal bacteria codes for the biosynthesis of symbiosis-specific cyclopeptides.

PNAS nexus

Avec: Sarah P Niehs , Kirstin Scherlach , Benjamin Dose , Zerrin Uzum , Timothy P Stinear , Sacha J Pidot , Christian Hertweck

Deazaflavin metabolite produced by endosymbiotic bacteria controls fungal host reproduction.

The ISME journal

Avec: Ingrid Richter , Mahmudul Hasan , Johannes W Kramer , Philipp Wein , Jana Krabbe , K Philip Woitas , Timothy P Stinear , Sacha J Pidot , Florian Kloss , Christian Hertweck , Gerald Lackner

Isopropanol at 60% and at 70% are effective against 'isopropanol-tolerant' Enterococcus faecium.

The Journal of hospital infection

Avec: J Gebel , S Gemein , G Kampf , S J Pidot , N Buetti , M Exner

Oak-Associated Negativicute Equipped with Ancestral Aromatic Polyketide Synthase Produces Antimycobacterial Dendrubins.

Chemistry (Weinheim an der Bergstrasse, Germany)

Avec: Keishi Ishida , Gulimila Shabuer , Sebastian Schieferdecker , Sacha J Pidot , Timothy P Stinear , Uwe Knuepfer , Michael Cyrulies , Christian Hertweck

Mining Symbionts of a Spider-Transmitted Fungus Illuminates Uncharted Biosynthetic Pathways to Cytotoxic Benzolactones.

Angewandte Chemie (International ed. in English)

Avec: Sarah P Niehs , Benjamin Dose , Sophie Richter , Sacha J Pidot , Hans-Martin Dahse , Timothy P Stinear , Christian Hertweck

Bacterial endosymbionts protect beneficial soil fungus from nematode attack.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Hannah Büttner , Sarah P Niehs , Koen Vandelannoote , Zoltán Cseresnyés , Benjamin Dose , Ingrid Richter , Ruman Gerst , Marc Thilo Figge , Timothy P Stinear , Sacha J Pidot , Christian Hertweck

Multi-Omic Analysis of Symbiotic Bacteria Associated With

Frontiers in microbiology

Avec: Katherine D Mosquera , Luis E Martinez Villegas , Sacha J Pidot , Chinhda Sharif , Sven Klimpel , Timothy P Stinear , Luciano A Moreira , Nicholas J Tobias , Marcelo G Lorenzo

Mycobacterium ulcerans challenge strain selection for a Buruli ulcer controlled human infection model.

PLoS neglected tropical diseases

Avec: Stephen Muhi , Andrew H Buultjens , Jessica L Porter , Julia L Marshall , Marcel Doerflinger , Sacha J Pidot , Daniel P O'Brien , Paul D R Johnson , Caroline J Lavender , Maria Globan , James McCarthy , Joshua Osowicki , Timothy P Stinear

Endofungal bacteria boost anthelminthic host protection with the biosurfactant symbiosin.

Chemical science

Avec: Hannah Büttner , Sacha J Pidot , Kirstin Scherlach , Christian Hertweck

Genomic exploration of coral-associated bacteria: identifying probiotic candidates to increase coral bleaching resilience in Galaxea fascicularis.

Microbiome

Avec: Talisa Doering , Kshitij Tandon , Sanjida H Topa , Sacha J Pidot , Linda L Blackall , Madeleine J H van Oppen

Transcription activator-like effectors from endosymbiotic bacteria control the reproduction of their fungal host.

mBio

Avec: Ingrid Richter , Zerrin Uzum , Philipp Wein , Evelyn M Molloy , Nadine Moebius , Timothy P Stinear , Sacha J Pidot , Christian Hertweck

Vaccine-Specific Immune Responses against Mycobacterium ulcerans Infection in a Low-Dose Murine Challenge Model.

Infection and immunity

Avec: Kirstie M Mangas , Andrew H Buultjens , Jessica L Porter , Sarah L Baines , Estelle Marion , Laurent Marsollier , Nicholas J Tobias , Sacha J Pidot , Kylie M Quinn , David J Price , Katherine Kedzierska , Weiguang Zeng , David C Jackson , Brendon Y Chua , Timothy P Stinear

Global analysis of adenylate-forming enzymes reveals β-lactone biosynthesis pathway in pathogenic

The Journal of biological chemistry

Avec: Serina L Robinson , Barbara R Terlouw , Megan D Smith , Sacha J Pidot , Timothy P Stinear , Marnix H Medema , Lawrence P Wackett

Identification and Mobilization of a Cryptic Antibiotic Biosynthesis Gene Locus from a Human-Pathogenic

ACS chemical biology

Avec: Marion Herisse , Keishi Ishida , Jessica L Porter , Ben Howden , Christian Hertweck , Timothy P Stinear , Sacha J Pidot

Zinc-binding to the cytoplasmic PAS domain regulates the essential WalK histidine kinase of Staphylococcus aureus.

Nature communications

Avec: Ian R Monk , Nausad Shaikh , Stephanie L Begg , Mike Gajdiss , Liam K R Sharkey , Jean Y H Lee , Sacha J Pidot , Torsten Seemann , Michael Kuiper , Brit Winnen , Rikki Hvorup , Brett M Collins , Gabriele Bierbaum , Saumya R Udagedara , Jacqueline R Morey , Neha Pulyani , Benjamin P Howden , Megan J Maher , Christopher A McDevitt , Glenn F King , Timothy P Stinear

Genomics-Driven Discovery of NO-Donating Diazeniumdiolate Siderophores in Diverse Plant-Associated Bacteria.

Angewandte Chemie (International ed. in English)

Avec: Ron Hermenau , Jule L Mehl , Keishi Ishida , Benjamin Dose , Sacha J Pidot , Timothy P Stinear , Christian Hertweck

Biosynthesis and Ether-Bridge Formation in Nargenicin Macrolides.

Angewandte Chemie (International ed. in English)

Avec: Sacha J Pidot , Marion Herisse , Liam Sharkey , Liselle Atkin , Jessica L Porter , Torsten Seemann , Benjamin P Howden , Mark A Rizzacasa , Timothy P Stinear

Genome Mining and Heterologous Expression Reveal Two Distinct Families of Lasso Peptides Highly Conserved in Endofungal Bacteria.

ACS chemical biology

Avec: Evgeni V Bratovanov , Keishi Ishida , Beatrix Heinze , Sacha J Pidot , Timothy P Stinear , Julian D Hegemann , Mohamed A Marahiel , Christian Hertweck

Symbiosis, virulence and natural-product biosynthesis in entomopathogenic bacteria are regulated by a small RNA.

Nature microbiology

Avec: Nick Neubacher , Nicholas J Tobias , Michaela Huber , Xiaofeng Cai , Timo Glatter , Sacha J Pidot , Timothy P Stinear , Anna Lena Lütticke , Kai Papenfort , Helge B Bode

Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria.

Nature chemistry

Avec: Yi-Ming Shi , Merle Hirschmann , Yan-Ni Shi , Shabbir Ahmed , Desalegne Abebew , Nicholas J Tobias , Peter Grün , Jan J Crames , Laura Pöschel , Wolfgang Kuttenlochner , Christian Richter , Jennifer Herrmann , Rolf Müller , Aunchalee Thanwisai , Sacha J Pidot , Timothy P Stinear , Michael Groll , Yonggyun Kim , Helge B Bode

Mobilization of cryptic antibiotic biosynthesis loci from human-pathogenic Nocardia.

Methods in enzymology

Avec: Marion Herisse , Sacha J Pidot

The two-component system WalKR provides an essential link between cell wall homeostasis and DNA replication in

mBio

Avec: Liam K R Sharkey , Romain Guerillot , Calum J Walsh , Adrianna M Turner , Jean Y H Lee , Stephanie L Neville , Stephan Klatt , Sarah L Baines , Sacha J Pidot , Fernando J Rossello , Torsten Seemann , Hamish E G McWilliam , Ellie Cho , Glen P Carter , Benjamin P Howden , Christopher A McDevitt , Abderrahman Hachani , Timothy P Stinear , Ian R Monk

Experimental infection of ringtail possums (Pseudocheirus peregrinus) with Mycobacterium ulcerans, the agent of Buruli ulcer.

Scientific reports

Avec: Kim R Blasdell , Richard J Ploeg , Emma C Hobbs , Stephen Muhi , Sarah J Riddell , Alexandra Cunneen , Michael L Kelly , Kate Maynard , Tess R Malcolm , Md Tanjir Islam , Victoria Boyd , Timothy P Stinear , Sacha J Pidot , Eugene Athan , Daniel P O'Brien

Réseau de co-auteurs

Timothy P Stinear 26 collaborations

Christian Hertweck 12 collaborations

Jessica L Porter 7 collaborations

Nicholas J Tobias 6 collaborations

Benjamin Dose 6 collaborations

Torsten Seemann 5 collaborations

Marion Herisse 5 collaborations

Sarah P Niehs 5 collaborations

Ian R Monk 4 collaborations

Kirstin Scherlach 4 collaborations

Benjamin P Howden 4 collaborations

Keishi Ishida 4 collaborations

Andrew H Buultjens 3 collaborations

Jean Y H Lee 3 collaborations

Helge B Bode 3 collaborations

Ingrid Richter 3 collaborations

Stephan Klatt 2 collaborations

Gregory M Cook 2 collaborations

Mark A Rizzacasa 2 collaborations

Kirstie M Mangas 2 collaborations

Estelle Marion 2 collaborations

Laurent Marsollier 2 collaborations

David C Jackson 2 collaborations

Brendon Y Chua 2 collaborations

Koen Vandelannoote 2 collaborations

Jana Krabbe 2 collaborations

Gerald Lackner 2 collaborations

Zerrin Uzum 2 collaborations

Philipp Wein 2 collaborations

Hannah Büttner 2 collaborations

Stephen Muhi 2 collaborations

Daniel P O'Brien 2 collaborations

Sarah L Baines 2 collaborations

Liam K R Sharkey 2 collaborations

Christopher A McDevitt 2 collaborations

Troy Lister 1 collaboration

Louis S Ates 1 collaboration

Wafa Frigui 1 collaboration

Fadel Sayes 1 collaboration

Laleh Majlessi 1 collaboration

Hiroshi Izumi 1 collaboration

Vicki Bennett-Wood 1 collaboration

Ashley Otter 1 collaboration

George Taiaroa 1 collaboration

Nicholas West 1 collaboration

John A Fuerst 1 collaboration

Michael D Stutz 1 collaboration

Marc Pellegrini 1 collaboration

Malcolm McConville 1 collaboration

Roland Brosch 1 collaboration

Brendon M Lee 1 collaboration

Liam K Harold 1 collaboration

Deepak V Almeida 1 collaboration

Livnat Afriat-Jurnou 1 collaboration

Htin Lin Aung 1 collaboration

Brian M Forde 1 collaboration

Kiel Hards 1 collaboration

F Hafna Ahmed 1 collaboration

A Elaaf Mohamed 1 collaboration

Matthew C Taylor 1 collaboration

Nicholas P West 1 collaboration

Chris Greening 1 collaboration

Scott A Beatson 1 collaboration

Eric L Nuermberger 1 collaboration

Colin J Jackson 1 collaboration

Emma Kenshole 1 collaboration

Michael Michael 1 collaboration

Arashdeep Kaur 1 collaboration

Isabelle B Pickles 1 collaboration

Mahima Sharma 1 collaboration

Niccolay Madeido Soler 1 collaboration

Nichollas E Scott 1 collaboration

Ethan D Goddard-Borger 1 collaboration

Gideon J Davies 1 collaboration

Spencer J Williams 1 collaboration

Jérémie Babonneau 1 collaboration

Chinn Yi Wong 1 collaboration

Lucy Li 1 collaboration

Liam K Sharkey 1 collaboration

Tuyet Hoang 1 collaboration

Ryan Musumba Awori 1 collaboration

Charles N Waturu 1 collaboration

Nelson O Amugune 1 collaboration

Friedrich J Ehinger 1 collaboration

Maria Dell 1 collaboration

Claudia Ross 1 collaboration

Mahmudul Hasan 1 collaboration

Johannes W Kramer 1 collaboration

K Philip Woitas 1 collaboration

Florian Kloss 1 collaboration

J Gebel 1 collaboration

S Gemein 1 collaboration

G Kampf 1 collaboration

S J Pidot 1 collaboration

N Buetti 1 collaboration

M Exner 1 collaboration

Gulimila Shabuer 1 collaboration

Sebastian Schieferdecker 1 collaboration

Uwe Knuepfer 1 collaboration

Michael Cyrulies 1 collaboration

Sophie Richter 1 collaboration

Hans-Martin Dahse 1 collaboration

Zoltán Cseresnyés 1 collaboration

Ruman Gerst 1 collaboration

Marc Thilo Figge 1 collaboration

Katherine D Mosquera 1 collaboration

Luis E Martinez Villegas 1 collaboration

Chinhda Sharif 1 collaboration

Sven Klimpel 1 collaboration

Luciano A Moreira 1 collaboration

Marcelo G Lorenzo 1 collaboration

Julia L Marshall 1 collaboration

Marcel Doerflinger 1 collaboration

Paul D R Johnson 1 collaboration

Caroline J Lavender 1 collaboration

Maria Globan 1 collaboration

James McCarthy 1 collaboration

Joshua Osowicki 1 collaboration

Talisa Doering 1 collaboration

Kshitij Tandon 1 collaboration

Sanjida H Topa 1 collaboration

Linda L Blackall 1 collaboration

Madeleine J H van Oppen 1 collaboration

Evelyn M Molloy 1 collaboration

Nadine Moebius 1 collaboration

Kylie M Quinn 1 collaboration

David J Price 1 collaboration

Katherine Kedzierska 1 collaboration

Weiguang Zeng 1 collaboration

Serina L Robinson 1 collaboration

Barbara R Terlouw 1 collaboration

Megan D Smith 1 collaboration

Marnix H Medema 1 collaboration

Lawrence P Wackett 1 collaboration

Ben Howden 1 collaboration

Nausad Shaikh 1 collaboration

Stephanie L Begg 1 collaboration

Mike Gajdiss 1 collaboration

Michael Kuiper 1 collaboration

Brit Winnen 1 collaboration

Rikki Hvorup 1 collaboration

Brett M Collins 1 collaboration

Gabriele Bierbaum 1 collaboration

Saumya R Udagedara 1 collaboration

Jacqueline R Morey 1 collaboration

Neha Pulyani 1 collaboration

Megan J Maher 1 collaboration

Glenn F King 1 collaboration

Ron Hermenau 1 collaboration

Jule L Mehl 1 collaboration

Liam Sharkey 1 collaboration

Liselle Atkin 1 collaboration

Evgeni V Bratovanov 1 collaboration

Beatrix Heinze 1 collaboration

Julian D Hegemann 1 collaboration

Mohamed A Marahiel 1 collaboration

Nick Neubacher 1 collaboration

Michaela Huber 1 collaboration

Xiaofeng Cai 1 collaboration

Timo Glatter 1 collaboration

Anna Lena Lütticke 1 collaboration

Kai Papenfort 1 collaboration

Yi-Ming Shi 1 collaboration

Merle Hirschmann 1 collaboration

Yan-Ni Shi 1 collaboration

Shabbir Ahmed 1 collaboration

Desalegne Abebew 1 collaboration

Peter Grün 1 collaboration

Jan J Crames 1 collaboration

Laura Pöschel 1 collaboration

Wolfgang Kuttenlochner 1 collaboration

Christian Richter 1 collaboration

Jennifer Herrmann 1 collaboration

Rolf Müller 1 collaboration

Aunchalee Thanwisai 1 collaboration

Michael Groll 1 collaboration

Yonggyun Kim 1 collaboration

Romain Guerillot 1 collaboration

Calum J Walsh 1 collaboration

Adrianna M Turner 1 collaboration

Stephanie L Neville 1 collaboration

Fernando J Rossello 1 collaboration

Hamish E G McWilliam 1 collaboration

Ellie Cho 1 collaboration

Glen P Carter 1 collaboration

Abderrahman Hachani 1 collaboration

Kim R Blasdell 1 collaboration

Richard J Ploeg 1 collaboration

Emma C Hobbs 1 collaboration

Sarah J Riddell 1 collaboration

Alexandra Cunneen 1 collaboration

Michael L Kelly 1 collaboration

Kate Maynard 1 collaboration

Tess R Malcolm 1 collaboration

Md Tanjir Islam 1 collaboration

Victoria Boyd 1 collaboration

Eugene Athan 1 collaboration