Simone Cavadini

Affiliations

Friedrich Miescher Institute for Biomedical Research, Maulbeerstrasse 66, 4058 Basel, Switzerland.

ORCID: 0000-0003-2777-7584

Publications (18)

Mechanisms of OCT4-SOX2 motif readout on nucleosomes.

Science (New York, N.Y.)

Avec: Alicia K Michael , Ralph S Grand , Luke Isbel , Simone Cavadini , Zuzanna Kozicka , Georg Kempf , Richard D Bunker , Andreas D Schenk , Alexandra Graff-Meyer , Ganesh R Pathare , Joscha Weiss , Syota Matsumoto , Lukas Burger , Dirk Schübeler , Nicolas H Thomä

UBR5 forms ligand-dependent complexes on chromatin to regulate nuclear hormone receptor stability.

Molecular cell

Avec: Jonathan M Tsai , Jacob D Aguirre , Yen-Der Li , Jared Brown , Vivian Focht , Lukas Kater , Georg Kempf , Brittany Sandoval , Stefan Schmitt , Justine C Rutter , Pius Galli , Colby R Sandate , Jevon A Cutler , Charles Zou , Katherine A Donovan , Ryan J Lumpkin , Simone Cavadini , Paul M C Park , Quinlan Sievers , Charlie Hatton , Elizabeth Ener , Brandon D Regalado , Micah T Sperling , Mikołaj Słabicki , Jeonghyeon Kim , Rebecca Zon , Zinan Zhang , Peter G Miller , Roger Belizaire , Adam S Sperling , Eric S Fischer , Rafael Irizarry , Scott A Armstrong , Nicolas H Thomä , Benjamin L Ebert

Structural basis of human separase regulation by securin and CDK1-cyclin B1.

Nature

Avec: Jun Yu , Pierre Raia , Chloe M Ghent , Tobias Raisch , Yashar Sadian , Simone Cavadini , Pramod M Sabale , David Barford , Stefan Raunser , David O Morgan , Andreas Boland

Deep quantification of substrate turnover defines protease subsite cooperativity.

Molecular systems biology

Avec: Rajani Kanth Gudipati , Dimos Gaidatzis , Jan Seebacher , Sandra Muehlhaeusser , Georg Kempf , Simone Cavadini , Daniel Hess , Charlotte Soneson , Helge Großhans

Dynamics of uS19 C-Terminal Tail during the Translation Elongation Cycle in Human Ribosomes.

Cell reports

Avec: Varun Bhaskar , Alexandra Graff-Meyer , Andreas D Schenk , Simone Cavadini , Ottilie von Loeffelholz , S Kundhavai Natchiar , Caroline G Artus-Revel , Hans-Rudolf Hotz , Gabriel Bretones , Bruno P Klaholz , Jeffrey A Chao

Publisher Correction: DNA damage detection in nucleosomes involves DNA register shifting.

Nature

Avec: Syota Matsumoto , Simone Cavadini , Richard D Bunker , Ralph S Grand , Alessandro Potenza , Julius Rabl , Junpei Yamamoto , Andreas D Schenk , Dirk Schübeler , Shigenori Iwai , Kaoru Sugasawa , Hitoshi Kurumizaka , Nicolas H Thomä

Dynamic association of human Ebp1 with the ribosome.

RNA (New York, N.Y.)

Avec: Varun Bhaskar , Jessica Desogus , Alexandra Graff-Meyer , Andreas D Schenk , Simone Cavadini , Jeffrey A Chao

The CRL4

The EMBO journal

Avec: Weaam I Mohamed , Andreas D Schenk , Georg Kempf , Simone Cavadini , Anja Basters , Alessandro Potenza , Wassim Abdul Rahman , Julius Rabl , Kurt Reichermeier , Nicolas H Thomä

Recognition of the CCT5 di-Glu degron by CRL4

The EMBO journal

Avec: Carlos Pla-Prats , Simone Cavadini , Georg Kempf , Nicolas H Thomä

Cooperation between bHLH transcription factors and histones for DNA access.

Nature

Avec: Alicia K Michael , Lisa Stoos , Priya Crosby , Nikolas Eggers , Xinyu Y Nie , Kristina Makasheva , Martina Minnich , Kelly L Healy , Joscha Weiss , Georg Kempf , Simone Cavadini , Lukas Kater , Jan Seebacher , Luca Vecchia , Deyasini Chakraborty , Luke Isbel , Ralph S Grand , Florian Andersch , Jennifer L Fribourgh , Dirk Schübeler , Johannes Zuber , Andrew C Liu , Peter B Becker , Beat Fierz , Carrie L Partch , Jerome S Menet , Nicolas H Thomä

DNA damage detection in nucleosomes involves DNA register shifting.

Nature

Avec: Syota Matsumoto , Simone Cavadini , Richard D Bunker , Ralph S Grand , Alessandro Potenza , Julius Rabl , Junpei Yamamoto , Andreas D Schenk , Dirk Schübeler , Shigenori Iwai , Kaoru Sugasawa , Hitoshi Kurumizaka , Nicolas H Thomä

Structure of the ciliogenesis-associated CPLANE complex.

Science advances

Avec: Gerasimos Langousis , Simone Cavadini , Niels Boegholm , Esben Lorentzen , Georg Kempf , Patrick Matthias

Designing Rigid DNA Origami Templates for Molecular Visualization Using Cryo-EM.

Nano letters

Avec: Ali Khoshouei , Georg Kempf , Volodymyr Mykhailiuk , Johanna Mariko Griessing , Maximilian Nicolas Honemann , Lukas Kater , Simone Cavadini , Hendrik Dietz

Live Analysis and Reconstruction of Single-Particle Cryo-Electron Microscopy Data with CryoFLARE.

Journal of chemical information and modeling

Avec: Andreas D Schenk , Simone Cavadini , Nicolas H Thomä , Christel Genoud

Structural mechanism of cGAS inhibition by the nucleosome.

Nature

Avec: Ganesh R Pathare , Alexiane Decout , Selene Glück , Simone Cavadini , Kristina Makasheva , Ruud Hovius , Georg Kempf , Joscha Weiss , Zuzanna Kozicka , Baptiste Guey , Pauline Melenec , Beat Fierz , Nicolas H Thomä , Andrea Ablasser

Structural Basis of BRCC36 Function in DNA Repair and Immune Regulation.

Molecular cell

Avec: Julius Rabl , Richard D Bunker , Andreas D Schenk , Simone Cavadini , Mark E Gill , Wassim Abdulrahman , Amparo Andrés-Pons , Martijn S Luijsterburg , Adel F M Ibrahim , Emma Branigan , Jacob D Aguirre , Aimee H Marceau , Claire Guérillon , Tewis Bouwmeester , Ulrich Hassiepen , Antoine H F M Peters , Martin Renatus , Laurent Gelman , Seth M Rubin , Niels Mailand , Haico van Attikum , Ronald T Hay , Nicolas H Thomä

Structure of the human C9orf72-SMCR8 complex reveals a multivalent protein interaction architecture.

PLoS biology

Avec: Julia Nörpel , Simone Cavadini , Andreas D Schenk , Alexandra Graff-Meyer , Daniel Hess , Jan Seebacher , Jeffrey A Chao , Varun Bhaskar

The genetic architecture of protein interaction affinity and specificity.

Nature communications

Avec: Alexandra M Bendel , Andre J Faure , Dominique Klein , Kenji Shimada , Romane Lyautey , Nicole Schiffelholz , Georg Kempf , Simone Cavadini , Ben Lehner , Guillaume Diss

Réseau de co-auteurs

Georg Kempf 10 collaborations

Nicolas H Thomä 10 collaborations

Andreas D Schenk 9 collaborations

Ralph S Grand 4 collaborations

Richard D Bunker 4 collaborations

Alexandra Graff-Meyer 4 collaborations

Dirk Schübeler 4 collaborations

Julius Rabl 4 collaborations

Joscha Weiss 3 collaborations

Syota Matsumoto 3 collaborations

Lukas Kater 3 collaborations

Jan Seebacher 3 collaborations

Varun Bhaskar 3 collaborations

Jeffrey A Chao 3 collaborations

Alessandro Potenza 3 collaborations

Alicia K Michael 2 collaborations

Luke Isbel 2 collaborations

Zuzanna Kozicka 2 collaborations

Ganesh R Pathare 2 collaborations

Jacob D Aguirre 2 collaborations

Daniel Hess 2 collaborations

Junpei Yamamoto 2 collaborations

Shigenori Iwai 2 collaborations

Kaoru Sugasawa 2 collaborations

Hitoshi Kurumizaka 2 collaborations

Kristina Makasheva 2 collaborations

Beat Fierz 2 collaborations

Lukas Burger 1 collaboration

Jonathan M Tsai 1 collaboration

Yen-Der Li 1 collaboration

Jared Brown 1 collaboration

Vivian Focht 1 collaboration

Brittany Sandoval 1 collaboration

Stefan Schmitt 1 collaboration

Justine C Rutter 1 collaboration

Pius Galli 1 collaboration

Colby R Sandate 1 collaboration

Jevon A Cutler 1 collaboration

Charles Zou 1 collaboration

Katherine A Donovan 1 collaboration

Ryan J Lumpkin 1 collaboration

Paul M C Park 1 collaboration

Quinlan Sievers 1 collaboration

Charlie Hatton 1 collaboration

Elizabeth Ener 1 collaboration

Brandon D Regalado 1 collaboration

Micah T Sperling 1 collaboration

Mikołaj Słabicki 1 collaboration

Jeonghyeon Kim 1 collaboration

Rebecca Zon 1 collaboration

Zinan Zhang 1 collaboration

Peter G Miller 1 collaboration

Roger Belizaire 1 collaboration

Adam S Sperling 1 collaboration

Eric S Fischer 1 collaboration

Rafael Irizarry 1 collaboration

Scott A Armstrong 1 collaboration

Benjamin L Ebert 1 collaboration

Jun Yu 1 collaboration

Pierre Raia 1 collaboration

Chloe M Ghent 1 collaboration

Tobias Raisch 1 collaboration

Yashar Sadian 1 collaboration

Pramod M Sabale 1 collaboration

David Barford 1 collaboration

Stefan Raunser 1 collaboration

David O Morgan 1 collaboration

Andreas Boland 1 collaboration

Rajani Kanth Gudipati 1 collaboration

Dimos Gaidatzis 1 collaboration

Sandra Muehlhaeusser 1 collaboration

Charlotte Soneson 1 collaboration

Helge Großhans 1 collaboration

Ottilie von Loeffelholz 1 collaboration

S Kundhavai Natchiar 1 collaboration

Caroline G Artus-Revel 1 collaboration

Hans-Rudolf Hotz 1 collaboration

Gabriel Bretones 1 collaboration

Bruno P Klaholz 1 collaboration

Jessica Desogus 1 collaboration

Weaam I Mohamed 1 collaboration

Anja Basters 1 collaboration

Wassim Abdul Rahman 1 collaboration

Kurt Reichermeier 1 collaboration

Carlos Pla-Prats 1 collaboration

Lisa Stoos 1 collaboration

Priya Crosby 1 collaboration

Nikolas Eggers 1 collaboration

Xinyu Y Nie 1 collaboration

Martina Minnich 1 collaboration

Kelly L Healy 1 collaboration

Luca Vecchia 1 collaboration

Deyasini Chakraborty 1 collaboration

Florian Andersch 1 collaboration

Jennifer L Fribourgh 1 collaboration

Johannes Zuber 1 collaboration

Andrew C Liu 1 collaboration

Peter B Becker 1 collaboration

Carrie L Partch 1 collaboration

Jerome S Menet 1 collaboration

Gerasimos Langousis 1 collaboration

Niels Boegholm 1 collaboration

Esben Lorentzen 1 collaboration

Patrick Matthias 1 collaboration

Ali Khoshouei 1 collaboration

Volodymyr Mykhailiuk 1 collaboration

Johanna Mariko Griessing 1 collaboration

Maximilian Nicolas Honemann 1 collaboration

Hendrik Dietz 1 collaboration

Christel Genoud 1 collaboration

Alexiane Decout 1 collaboration

Selene Glück 1 collaboration

Ruud Hovius 1 collaboration

Baptiste Guey 1 collaboration

Pauline Melenec 1 collaboration

Andrea Ablasser 1 collaboration

Mark E Gill 1 collaboration

Wassim Abdulrahman 1 collaboration

Amparo Andrés-Pons 1 collaboration

Martijn S Luijsterburg 1 collaboration

Adel F M Ibrahim 1 collaboration

Emma Branigan 1 collaboration

Aimee H Marceau 1 collaboration

Claire Guérillon 1 collaboration

Tewis Bouwmeester 1 collaboration

Ulrich Hassiepen 1 collaboration

Antoine H F M Peters 1 collaboration

Martin Renatus 1 collaboration

Laurent Gelman 1 collaboration

Seth M Rubin 1 collaboration

Niels Mailand 1 collaboration

Haico van Attikum 1 collaboration

Ronald T Hay 1 collaboration

Julia Nörpel 1 collaboration

Alexandra M Bendel 1 collaboration

Andre J Faure 1 collaboration

Dominique Klein 1 collaboration

Kenji Shimada 1 collaboration

Romane Lyautey 1 collaboration

Nicole Schiffelholz 1 collaboration

Ben Lehner 1 collaboration

Guillaume Diss 1 collaboration