Stephen N Gomperts

Affiliations

From the APDA Center for Advanced Parkinson Research (Y.E.H., J.J.L., Z.L., G.L., K.C., Y.I.K., I.T., M.T.H., C.R.S.) and Precision Neurology Program (Y.E.H., Z.L., G.L., Y.I.K., C.R.S.), Harvard Medical School, and Department of Neurology (Y.E.H., G.L., C.R.S.), Brigham and Women's Hospital, Boston, MA; Department of Neurology (Y.E.H.), CHA Bundang Medical Center, CHA University, Seongnam, Korea; Rare and Neurological Diseases Therapeutic Area (M.S.R.C., S.P.S.), Sanofi, Framingham, MA; School of Medicine (G.L.), Sun Yat-Sen University, Guangzhou, Guangdong, China; and Department of Neurology (J.J.L., A.V., A.L.H., M.A.S., A.Y.H., T.M.H., B.T.H., A.-M.W., S.N.G., J.H.G., C.R.S.), Massachusetts General Hospital, Boston.

Publications (28)

β-Glucocerebrosidase activity in

Neurology

Avec: Young Eun Huh , Ming Sum Ruby Chiang , Joseph J Locascio , Zhixiang Liao , Ganqiang Liu , Karbi Choudhury , Yuliya I Kuras , Idil Tuncali , Aleksandar Videnovic , Ann L Hunt , Michael A Schwarzschild , Albert Y Hung , Todd M Herrington , Michael T Hayes , Bradley T Hyman , Anne-Marie Wills , Stephen N Gomperts , John H Growdon , Sergio Pablo Sardi , Clemens R Scherzer

Serum NFL levels predict progression of motor impairment and reduction in putamen dopamine transporter binding ratios in de novo Parkinson's disease: An 8-year longitudinal study.

Parkinsonism & related disorders

Avec: Rong Ye , Joseph J Locascio , Anna E Goodheart , Moqing Quan , Baorong Zhang , Stephen N Gomperts

Optogenetic targeting of astrocytes restores slow brain rhythm function and slows Alzheimer's disease pathology.

Scientific reports

Avec: Yee Fun Lee , Alyssa N Russ , Qiuchen Zhao , Stephen J Perle , Megi Maci , Morgan R Miller , Steven S Hou , Moustafa Algamal , Zhuoyang Zhao , Hanyan Li , Noah Gelwan , Zhe Liu , Stephen N Gomperts , Alfonso Araque , Elena Galea , Brian J Bacskai , Ksenia V Kastanenka

Clearing the Smoke: What Protects Smokers from Parkinson's Disease?

Movement disorders : official journal of the Movement Disorder Society

Avec: Kenneth N Rose , Michael A Schwarzschild , Stephen N Gomperts

Sleep restoration by optogenetic targeting of GABAergic neurons reprograms microglia and ameliorates pathological phenotypes in an Alzheimer's disease model.

Molecular neurodegeneration

Avec: Qiuchen Zhao , Megi Maci , Morgan R Miller , Heng Zhou , Fang Zhang , Moustafa Algamal , Yee Fun Lee , Steven S Hou , Stephen J Perle , Hoang Le , Alyssa N Russ , Eng H Lo , Dmitry Gerashchenko , Stephen N Gomperts , Brian J Bacskai , Ksenia V Kastanenka

Research criteria for the diagnosis of prodromal dementia with Lewy bodies.

Neurology

Avec: Ian G McKeith , Tanis J Ferman , Alan J Thomas , Frédéric Blanc , Bradley F Boeve , Hiroshige Fujishiro , Kejal Kantarci , Cristina Muscio , John T O'Brien , Ronald B Postuma , Dag Aarsland , Clive Ballard , Laura Bonanni , Paul Donaghy , Murat Emre , James E Galvin , Douglas Galasko , Jennifer G Goldman , Stephen N Gomperts , Lawrence S Honig , Manabu Ikeda , James B Leverenz , Simon J G Lewis , Karen S Marder , Mario Masellis , David P Salmon , John Paul Taylor , Debby W Tsuang , Zuzana Walker , Pietro Tiraboschi , Auteur inconnu

Neuropathologic correlates of amyloid and dopamine transporter imaging in Lewy body disease.

Neurology

Avec: Julia Shirvan , Nathan Clement , Rong Ye , Samantha Katz , Aaron Schultz , Keith A Johnson , Teresa Gomez-Isla , Matthew Frosch , John H Growdon , Stephen N Gomperts

Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration.

Nature communications

Avec: Ying Jiang , John J Alam , Stephen N Gomperts , Paul Maruff , Afina W Lemstra , Ursula A Germann , Philip H Stavrides , Sandipkumar Darji , Sandeep Malampati , James Peddy , Cynthia Bleiwas , Monika Pawlik , Anna Pensalfini , Dun-Sheng Yang , Shivakumar Subbanna , Balapal S Basavarajappa , John F Smiley , Amanda Gardner , Kelly Blackburn , Hui-May Chu , Niels D Prins , Charlotte E Teunissen , John E Harrison , Philip Scheltens , Ralph A Nixon

Sleep functional connectivity, hyperexcitability, and cognition in Alzheimer's disease.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Avec: Sebastian G Moguilner , Courtney Berezuk , Alex C Bender , Kyle R Pellerin , Stephen N Gomperts , Sydney S Cash , Rani A Sarkis , Alice D Lam

Optogenetic targeting of cortical astrocytes selectively improves NREM sleep in an Alzheimer's disease mouse model.

Scientific reports

Avec: Qiuchen Zhao , Shinya Yokomizo , Stephen J Perle , Yee Fun Lee , Heng Zhou , Morgan R Miller , Hanyan Li , Dmitry Gerashchenko , Stephen N Gomperts , Brian J Bacskai , Ksenia V Kastanenka

Cholinergic modulation of hippocampal calcium activity across the sleep-wake cycle.

eLife

Avec: Heng Zhou , Kevin R Neville , Nitsan Goldstein , Shushi Kabu , Naila Kausar , Rong Ye , Thuan Tinh Nguyen , Noah Gelwan , Bradley T Hyman , Stephen N Gomperts

Topography of cortical thinning in the Lewy body diseases.

NeuroImage. Clinical

Avec: Rong Ye , Alexandra Touroutoglou , Michael Brickhouse , Samantha Katz , John H Growdon , Keith A Johnson , Bradford C Dickerson , Stephen N Gomperts

EEG Entropy in REM Sleep as a Physiologic Biomarker in Early Clinical Stages of Alzheimer's Disease.

Journal of Alzheimer's disease : JAD

Avec: Hamed Azami , Sebastian Moguilner , Hector Penagos , Rani A Sarkis , Steven E Arnold , Stephen N Gomperts , Alice D Lam

Optogenetic Targeting of Astrocytes Restores Slow Brain Rhythm Function and Slows Alzheimer's Disease Pathology.

Research square

Avec: Yee Fun Lee , Alyssa N Russ , Qiuchen Zhao , Megi Maci , Morgan R Miller , Steven S Hou , Moustafa Algamal , Zhuoyang Zhao , Hanyan Li , Noah Gelwan , Stephen N Gomperts , Alfonso Araque , Elena Galea , Brian J Bacskai , Ksenia V Kastanenka

Neuroprotection of low dose carbon monoxide in Parkinson's disease models commensurate with the reduced risk of Parkinson's among smokers.

bioRxiv : the preprint server for biology

Avec: K N Rose , M Zorlu , X Xue , A Fassini , W Cai , S Lin , P Webb , M A Schwarzschild , X Chen , S N Gomperts

Neuroprotection of low dose carbon monoxide in Parkinson's disease models commensurate with the reduced risk of Parkinson's among smokers.

NPJ Parkinson's disease

Avec: K N Rose , M Zorlu , A Fassini , H Lee , W Cai , X Xue , S Lin , P Kivisakk , M A Schwarzschild , X Chen , S N Gomperts

18F-AV-1451 positron emission tomography in neuropathological substrates of corticobasal syndrome.

Brain : a journal of neurology

Avec: Anna E Goodheart , Joseph J Locascio , Wesley R Samore , Jessica A Collins , Michael Brickhouse , Aaron Schultz , Alexandra Touroutoglou , Keith A Johnson , Matthew P Frosch , John H Growdon , Bradford C Dickerson , Stephen N Gomperts

Disruption of hippocampal neuronal circuit function depends upon behavioral state in the APP/PS1 mouse model of Alzheimer's disease.

Scientific reports

Avec: Heng Zhou , Hanyan Li , Niket Gowravaram , Moqin Quan , Naila Kausar , Stephen N Gomperts

Lewy body dementia: Overcoming barriers and identifying solutions.

Alzheimer's & dementia : the journal of the Alzheimer's Association

Avec: Kanishka Agarwal , Wendi Backler , Ece Bayram , Leah Bloom , Bradley F Boeve , Jang-Ho Cha , Maria Denslow , Tanis J Ferman , Douglas Galasko , James E Galvin , Stephen N Gomperts , Michael C Irizarry , Kejal Kantarci , Harsh Kaushik , Matt Kietlinski , Aaron Koenig , James B Leverenz , Ian McKeith , Pamela J McLean , Thomas J Montine , Sandra O Moose , John T O'Brien , Valery Panier , Sharad Ramanathan , Michael S Ringel , Sonja W Scholz , Jonnell Small , Reisa A Sperling , Angela Taylor , John-Paul Taylor , Rebecca A Ward , Lisa Witten , Bradley T Hyman

Cellular resolution contributions to ictal population signals.

Epilepsia

Avec: Lauren A Lau , Zhuoyang Zhao , Stephen N Gomperts , Kevin J Staley , Kyle P Lillis

The association between cigarette smoking and dementia with Lewy bodies.

Parkinsonism & related disorders

Avec: Anna E Goodheart , Stephen N Gomperts

Frequency-dependent exacerbation of Alzheimer's disease neuropathophysiology.

Scientific reports

Avec: Ksenia V Kastanenka , Maria Calvo-Rodriguez , Steven S Hou , Heng Zhou , Shuko Takeda , Michal Arbel-Ornath , Amanda Lariviere , Yee Fun Lee , Alex Kim , Jonathan M Hawkes , Robert Logan , Danielle Feng , Xiqun Chen , Stephen N Gomperts , Brian J Bacskai

Associations of Lower Caffeine Intake and Plasma Urate Levels with Idiopathic Parkinson's Disease in the Harvard Biomarkers Study.

Journal of Parkinson's disease

Avec: Rachit Bakshi , Eric A Macklin , Albert Y Hung , Michael T Hayes , Bradley T Hyman , Anne-Marie Wills , Stephen N Gomperts , John H Growdon , Alberto Ascherio , Clemens R Scherzer , Michael A Schwarzschild

Fluid and Tissue Biomarkers of Lewy Body Dementia: Report of an LBDA Symposium.

Frontiers in neurology

Avec: Gregory D Scott , Moriah R Arnold , Thomas G Beach , Christopher H Gibbons , Anumantha G Kanthasamy , Russell M Lebovitz , Afina W Lemstra , Leslie M Shaw , Charlotte E Teunissen , Henrik Zetterberg , Angela S Taylor , Todd C Graham , Bradley F Boeve , Stephen N Gomperts , Neill R Graff-Radford , Charbel Moussa , Kathleen L Poston , Liana S Rosenthal , Marwan N Sabbagh , Ryan R Walsh , Miriam T Weber , Melissa J Armstrong , Jee A Bang , Andrea C Bozoki , Kimiko Domoto-Reilly , John E Duda , Jori E Fleisher , Douglas R Galasko , James E Galvin , Jennifer G Goldman , Samantha K Holden , Lawrence S Honig , Daniel E Huddleston , James B Leverenz , Irene Litvan , Carol A Manning , Karen S Marder , Alexander Y Pantelyat , Victoria S Pelak , Douglas W Scharre , Sharon J Sha , Holly A Shill , Zoltan Mari , Joseph F Quinn , David J Irwin

Association of Plasma Phosphorylated Tau With the Response to Neflamapimod Treatment in Patients With Dementia With Lewy Bodies.

Neurology

Avec: John J Alam , Paul Maruff , Susan R Doctrow , Hui-May Chu , Jennifer Conway , Stephen N Gomperts , Charlotte Teunissen

Impaired Hippocampal Reactivation Preceding Robust Aβ Deposition in a Model of Alzheimer's Disease.

bioRxiv : the preprint server for biology

Avec: Hanyan Li , Zhuoyang Zhao , Aline Fassini , Han K Lee , Reese J Green , Stephen N Gomperts

Differential Vulnerability of Hippocampal Subfields to Amyloid and Tau Deposition in the Lewy Body Diseases.

Neurology

Avec: Rong Ye , Anna E Goodheart , Joseph J Locascio , Erin Peterec , Michael Properzi , Emma G Thibault , Erin Chuba , Keith A Johnson , Michael J Brickhouse , Alexandra Touroutoglou , John H Growdon , Bradford C Dickerson , Stephen N Gomperts

Development of a New Positron Emission Tomography Imaging Radioligand Targeting RIPK1 in the Brain and Characterization in Alzheimer's Disease.

Advanced science (Weinheim, Baden-Wurttemberg, Germany)

Avec: Ping Bai , Yu Lan , Yan Liu , Prasenjit Mondal , Ashley Gomm , Yulong Xu , Yanli Wang , Yongle Wang , Leyi Kang , Lili Pan , Frederick A Bagdasarian , Madelyn Hallisey , Breanna Varela , Se Hoon Choi , Stephen N Gomperts , Hsiao-Ying Wey , Shiqian Shen , Rudolph E Tanzi , Changning Wang , Can Zhang

Réseau de co-auteurs

John H Growdon 6 collaborations

Rong Ye 5 collaborations

Yee Fun Lee 5 collaborations

Hanyan Li 5 collaborations

Brian J Bacskai 5 collaborations

Ksenia V Kastanenka 5 collaborations

Heng Zhou 5 collaborations

Joseph J Locascio 4 collaborations

Bradley T Hyman 4 collaborations

Anna E Goodheart 4 collaborations

Qiuchen Zhao 4 collaborations

Morgan R Miller 4 collaborations

Steven S Hou 4 collaborations

Zhuoyang Zhao 4 collaborations

Keith A Johnson 4 collaborations

Michael A Schwarzschild 3 collaborations

Alyssa N Russ 3 collaborations

Stephen J Perle 3 collaborations

Megi Maci 3 collaborations

Moustafa Algamal 3 collaborations

Noah Gelwan 3 collaborations

Bradley F Boeve 3 collaborations

James E Galvin 3 collaborations

James B Leverenz 3 collaborations

Alexandra Touroutoglou 3 collaborations

Bradford C Dickerson 3 collaborations

Albert Y Hung 2 collaborations

Michael T Hayes 2 collaborations

Anne-Marie Wills 2 collaborations

Clemens R Scherzer 2 collaborations

Alfonso Araque 2 collaborations

Elena Galea 2 collaborations

Dmitry Gerashchenko 2 collaborations

Tanis J Ferman 2 collaborations

Kejal Kantarci 2 collaborations

John T O'Brien 2 collaborations

Douglas Galasko 2 collaborations

Jennifer G Goldman 2 collaborations

Lawrence S Honig 2 collaborations

Karen S Marder 2 collaborations

Samantha Katz 2 collaborations

Aaron Schultz 2 collaborations

John J Alam 2 collaborations

Paul Maruff 2 collaborations

Afina W Lemstra 2 collaborations

Hui-May Chu 2 collaborations

Charlotte E Teunissen 2 collaborations

Rani A Sarkis 2 collaborations

Alice D Lam 2 collaborations

Naila Kausar 2 collaborations

Michael Brickhouse 2 collaborations

K N Rose 2 collaborations

M Zorlu 2 collaborations

X Xue 2 collaborations

A Fassini 2 collaborations

W Cai 2 collaborations

S Lin 2 collaborations

M A Schwarzschild 2 collaborations

X Chen 2 collaborations

S N Gomperts 2 collaborations

Young Eun Huh 1 collaboration

Ming Sum Ruby Chiang 1 collaboration

Zhixiang Liao 1 collaboration

Ganqiang Liu 1 collaboration

Karbi Choudhury 1 collaboration

Yuliya I Kuras 1 collaboration

Idil Tuncali 1 collaboration

Aleksandar Videnovic 1 collaboration

Ann L Hunt 1 collaboration

Todd M Herrington 1 collaboration

Sergio Pablo Sardi 1 collaboration

Moqing Quan 1 collaboration

Baorong Zhang 1 collaboration

Zhe Liu 1 collaboration

Kenneth N Rose 1 collaboration

Fang Zhang 1 collaboration

Hoang Le 1 collaboration

Eng H Lo 1 collaboration

Ian G McKeith 1 collaboration

Alan J Thomas 1 collaboration

Frédéric Blanc 1 collaboration

Hiroshige Fujishiro 1 collaboration

Cristina Muscio 1 collaboration

Ronald B Postuma 1 collaboration

Dag Aarsland 1 collaboration

Clive Ballard 1 collaboration

Laura Bonanni 1 collaboration

Paul Donaghy 1 collaboration

Murat Emre 1 collaboration

Manabu Ikeda 1 collaboration

Simon J G Lewis 1 collaboration

Mario Masellis 1 collaboration

David P Salmon 1 collaboration

John Paul Taylor 1 collaboration

Debby W Tsuang 1 collaboration

Zuzana Walker 1 collaboration

Pietro Tiraboschi 1 collaboration

None None 1 collaboration

Julia Shirvan 1 collaboration

Nathan Clement 1 collaboration

Teresa Gomez-Isla 1 collaboration

Matthew Frosch 1 collaboration

Ying Jiang 1 collaboration

Ursula A Germann 1 collaboration

Philip H Stavrides 1 collaboration

Sandipkumar Darji 1 collaboration

Sandeep Malampati 1 collaboration

James Peddy 1 collaboration

Cynthia Bleiwas 1 collaboration

Monika Pawlik 1 collaboration

Anna Pensalfini 1 collaboration

Dun-Sheng Yang 1 collaboration

Shivakumar Subbanna 1 collaboration

Balapal S Basavarajappa 1 collaboration

John F Smiley 1 collaboration

Amanda Gardner 1 collaboration

Kelly Blackburn 1 collaboration

Niels D Prins 1 collaboration

John E Harrison 1 collaboration

Philip Scheltens 1 collaboration

Ralph A Nixon 1 collaboration

Sebastian G Moguilner 1 collaboration

Courtney Berezuk 1 collaboration

Alex C Bender 1 collaboration

Kyle R Pellerin 1 collaboration

Sydney S Cash 1 collaboration

Shinya Yokomizo 1 collaboration

Kevin R Neville 1 collaboration

Nitsan Goldstein 1 collaboration

Shushi Kabu 1 collaboration

Thuan Tinh Nguyen 1 collaboration

Hamed Azami 1 collaboration

Sebastian Moguilner 1 collaboration

Hector Penagos 1 collaboration

Steven E Arnold 1 collaboration

P Webb 1 collaboration

H Lee 1 collaboration

P Kivisakk 1 collaboration

Wesley R Samore 1 collaboration

Jessica A Collins 1 collaboration

Matthew P Frosch 1 collaboration

Niket Gowravaram 1 collaboration

Moqin Quan 1 collaboration

Kanishka Agarwal 1 collaboration

Wendi Backler 1 collaboration

Ece Bayram 1 collaboration

Leah Bloom 1 collaboration

Jang-Ho Cha 1 collaboration

Maria Denslow 1 collaboration

Michael C Irizarry 1 collaboration

Harsh Kaushik 1 collaboration

Matt Kietlinski 1 collaboration

Aaron Koenig 1 collaboration

Ian McKeith 1 collaboration

Pamela J McLean 1 collaboration

Thomas J Montine 1 collaboration

Sandra O Moose 1 collaboration

Valery Panier 1 collaboration

Sharad Ramanathan 1 collaboration

Michael S Ringel 1 collaboration

Sonja W Scholz 1 collaboration

Jonnell Small 1 collaboration

Reisa A Sperling 1 collaboration

Angela Taylor 1 collaboration

John-Paul Taylor 1 collaboration

Rebecca A Ward 1 collaboration

Lisa Witten 1 collaboration

Lauren A Lau 1 collaboration

Kevin J Staley 1 collaboration

Kyle P Lillis 1 collaboration

Maria Calvo-Rodriguez 1 collaboration

Shuko Takeda 1 collaboration

Michal Arbel-Ornath 1 collaboration

Amanda Lariviere 1 collaboration

Alex Kim 1 collaboration

Jonathan M Hawkes 1 collaboration

Robert Logan 1 collaboration

Danielle Feng 1 collaboration

Xiqun Chen 1 collaboration

Rachit Bakshi 1 collaboration

Eric A Macklin 1 collaboration

Alberto Ascherio 1 collaboration

Gregory D Scott 1 collaboration

Moriah R Arnold 1 collaboration

Thomas G Beach 1 collaboration

Christopher H Gibbons 1 collaboration

Anumantha G Kanthasamy 1 collaboration

Russell M Lebovitz 1 collaboration

Leslie M Shaw 1 collaboration

Henrik Zetterberg 1 collaboration

Angela S Taylor 1 collaboration

Todd C Graham 1 collaboration

Neill R Graff-Radford 1 collaboration

Charbel Moussa 1 collaboration

Kathleen L Poston 1 collaboration

Liana S Rosenthal 1 collaboration

Marwan N Sabbagh 1 collaboration

Ryan R Walsh 1 collaboration

Miriam T Weber 1 collaboration

Melissa J Armstrong 1 collaboration

Jee A Bang 1 collaboration

Andrea C Bozoki 1 collaboration

Kimiko Domoto-Reilly 1 collaboration

John E Duda 1 collaboration

Jori E Fleisher 1 collaboration

Douglas R Galasko 1 collaboration

Samantha K Holden 1 collaboration

Daniel E Huddleston 1 collaboration

Irene Litvan 1 collaboration

Carol A Manning 1 collaboration

Alexander Y Pantelyat 1 collaboration

Victoria S Pelak 1 collaboration

Douglas W Scharre 1 collaboration

Sharon J Sha 1 collaboration

Holly A Shill 1 collaboration

Zoltan Mari 1 collaboration

Joseph F Quinn 1 collaboration

David J Irwin 1 collaboration

Susan R Doctrow 1 collaboration

Jennifer Conway 1 collaboration

Charlotte Teunissen 1 collaboration

Aline Fassini 1 collaboration

Han K Lee 1 collaboration

Reese J Green 1 collaboration

Erin Peterec 1 collaboration

Michael Properzi 1 collaboration

Emma G Thibault 1 collaboration

Erin Chuba 1 collaboration

Michael J Brickhouse 1 collaboration

Ping Bai 1 collaboration

Yu Lan 1 collaboration

Yan Liu 1 collaboration

Prasenjit Mondal 1 collaboration

Ashley Gomm 1 collaboration

Yulong Xu 1 collaboration

Yanli Wang 1 collaboration

Yongle Wang 1 collaboration

Leyi Kang 1 collaboration

Lili Pan 1 collaboration

Frederick A Bagdasarian 1 collaboration

Madelyn Hallisey 1 collaboration

Breanna Varela 1 collaboration

Se Hoon Choi 1 collaboration

Hsiao-Ying Wey 1 collaboration

Shiqian Shen 1 collaboration

Rudolph E Tanzi 1 collaboration

Changning Wang 1 collaboration

Can Zhang 1 collaboration