Sandipkumar Darji

Affiliations

Center for Dementia Research, Nathan Kline Institute for Psychiatric Research, Orangeburg, NY 10962, USA.

Publications (12)

Endosomal Dysfunction Induced by Directly Overactivating Rab5 Recapitulates Prodromal and Neurodegenerative Features of Alzheimer's Disease.

Cell reports

Avec: Anna Pensalfini , Seonil Kim , Shivakumar Subbanna , Cynthia Bleiwas , Chris N Goulbourne , Philip H Stavrides , Ying Jiang , Ju-Hyun Lee , Sandipkumar Darji , Monika Pawlik , Chunfeng Huo , James Peddy , Martin J Berg , John F Smiley , Balapal S Basavarajappa , Ralph A Nixon

Engineering Catharanthus roseus monoterpenoid indole alkaloid pathway in yeast.

Applied microbiology and biotechnology

Avec: Vyoma Mistry , Siddhi Darji , Pragya Tiwari , Abhishek Sharma

Targeted elastin-like polypeptide fusion protein for near-infrared imaging of human and canine urothelial carcinoma.

Oncotarget

Avec: Aayush Aayush , Saloni Darji , Deepika Dhawan , Alexander Enstrom , Meaghan M Broman , Muhammad T Idrees , Hristos Kaimakliotis , Timothy Ratliff , Deborah Knapp , David Thompson

Preclinical and randomized clinical evaluation of the p38α kinase inhibitor neflamapimod for basal forebrain cholinergic degeneration.

Nature communications

Avec: Ying Jiang , John J Alam , Stephen N Gomperts , Paul Maruff , Afina W Lemstra , Ursula A Germann , Philip H Stavrides , Sandipkumar Darji , Sandeep Malampati , James Peddy , Cynthia Bleiwas , Monika Pawlik , Anna Pensalfini , Dun-Sheng Yang , Shivakumar Subbanna , Balapal S Basavarajappa , John F Smiley , Amanda Gardner , Kelly Blackburn , Hui-May Chu , Niels D Prins , Charlotte E Teunissen , John E Harrison , Philip Scheltens , Ralph A Nixon

Development of an Elastin-like Polypeptide-Based Nucleic Acid Delivery System Targeted to EGFR+ Bladder Cancer Cells Using a Layer-by-Layer Approach.

Biomacromolecules

Avec: Aayush Aayush , Saloni Darji , Kiera M Estes , Emily Yeh , David H Thompson

Recent Advances in Drug Delivery Strategies for High-Risk BCG-Unresponsive Non-Muscle Invasive Bladder Cancer: A Brief Review from 2018 to 2024.

Pharmaceutics

Avec: Feng Qu , Saloni Darji , David H Thompson

Lysosomal dysfunction in Down syndrome and Alzheimer mouse models is caused by v-ATPase inhibition by Tyr

Science advances

Avec: Eunju Im , Ying Jiang , Philip H Stavrides , Sandipkumar Darji , Hediye Erdjument-Bromage , Thomas A Neubert , Jun Yong Choi , Jerzy Wegiel , Ju-Hyun Lee , Ralph A Nixon

β2-adrenergic Agonists Rescue Lysosome Acidification and Function in PSEN1 Deficiency by Reversing Defective ER-to-lysosome Delivery of ClC-7.

Journal of molecular biology

Avec: Ju-Hyun Lee , Devin M Wolfe , Sandipkumar Darji , Mary Kate McBrayer , Daniel J Colacurcio , Asok Kumar , Philip Stavrides , Panaiyur S Mohan , Ralph A Nixon

Unravelling the Mechanism of Elastin-like Polypeptide-Enzyme Fusion Stabilization in Organic Solvents.

Biomacromolecules

Avec: Saloni Darji , Aayush Aayush , Kiera M Estes , Jocie D Strock , David H Thompson

mTOR hyperactivation in Down Syndrome underlies deficits in autophagy induction, autophagosome formation, and mitophagy.

Cell death & disease

Avec: Matteo Bordi , Sandipkumar Darji , Yutaka Sato , Marian Mellén , Martin J Berg , Asok Kumar , Ying Jiang , Ralph A Nixon

Lysosomal Dysfunction in Down Syndrome Is APP-Dependent and Mediated by APP-βCTF (C99).

The Journal of neuroscience : the official journal of the Society for Neuroscience

Avec: Ying Jiang , Yutaka Sato , Eunju Im , Martin Berg , Matteo Bordi , Sandipkumar Darji , Asok Kumar , Panaiyur S Mohan , Urmi Bandyopadhyay , Antonio Diaz , Ana Maria Cuervo , Ralph A Nixon

Autophagy is a novel pathway for neurofilament protein degradation

Autophagy

Avec: Mala V Rao , Sandipkumar Darji , Philip H Stavrides , Chris N Goulbourne , Asok Kumar , Dun-Sheng Yang , Lang Yoo , James Peddy , Ju-Hyun Lee , Aidong Yuan , Ralph A Nixon

Réseau de co-auteurs

Ralph A Nixon 7 collaborations

Ying Jiang 5 collaborations

Philip H Stavrides 4 collaborations

Ju-Hyun Lee 4 collaborations

Saloni Darji 4 collaborations

Asok Kumar 4 collaborations

James Peddy 3 collaborations

Aayush Aayush 3 collaborations

David H Thompson 3 collaborations

Anna Pensalfini 2 collaborations

Shivakumar Subbanna 2 collaborations

Cynthia Bleiwas 2 collaborations

Chris N Goulbourne 2 collaborations

Monika Pawlik 2 collaborations

Martin J Berg 2 collaborations

John F Smiley 2 collaborations

Balapal S Basavarajappa 2 collaborations

Dun-Sheng Yang 2 collaborations

Kiera M Estes 2 collaborations

Eunju Im 2 collaborations

Panaiyur S Mohan 2 collaborations

Matteo Bordi 2 collaborations

Yutaka Sato 2 collaborations

Seonil Kim 1 collaboration

Chunfeng Huo 1 collaboration

Vyoma Mistry 1 collaboration

Siddhi Darji 1 collaboration

Pragya Tiwari 1 collaboration

Abhishek Sharma 1 collaboration

Deepika Dhawan 1 collaboration

Alexander Enstrom 1 collaboration

Meaghan M Broman 1 collaboration

Muhammad T Idrees 1 collaboration

Hristos Kaimakliotis 1 collaboration

Timothy Ratliff 1 collaboration

Deborah Knapp 1 collaboration

David Thompson 1 collaboration

John J Alam 1 collaboration

Stephen N Gomperts 1 collaboration

Paul Maruff 1 collaboration

Afina W Lemstra 1 collaboration

Ursula A Germann 1 collaboration

Sandeep Malampati 1 collaboration

Amanda Gardner 1 collaboration

Kelly Blackburn 1 collaboration

Hui-May Chu 1 collaboration

Niels D Prins 1 collaboration

Charlotte E Teunissen 1 collaboration

John E Harrison 1 collaboration

Philip Scheltens 1 collaboration

Emily Yeh 1 collaboration

Feng Qu 1 collaboration

Hediye Erdjument-Bromage 1 collaboration

Thomas A Neubert 1 collaboration

Jun Yong Choi 1 collaboration

Jerzy Wegiel 1 collaboration

Devin M Wolfe 1 collaboration

Mary Kate McBrayer 1 collaboration

Daniel J Colacurcio 1 collaboration

Philip Stavrides 1 collaboration

Jocie D Strock 1 collaboration

Marian Mellén 1 collaboration

Martin Berg 1 collaboration

Urmi Bandyopadhyay 1 collaboration

Antonio Diaz 1 collaboration

Ana Maria Cuervo 1 collaboration

Mala V Rao 1 collaboration

Lang Yoo 1 collaboration

Aidong Yuan 1 collaboration