Sven-Kevin Hotop

Affiliations

Department of Chemical Biology , Helmholtz Centre for Infection Research and German Centre for Infection Research (DZIF) , 38124 Braunschweig , Germany.

Publications (18)

Serological Analysis of Herpes B Virus at Individual Epitope Resolution: From Two-Dimensional Peptide Arrays to Multiplex Bead Flow Assays.

Analytical chemistry

Avec: Sven-Kevin Hotop , Ahmed Abd El Wahed , Ulrike Beutling , Florian Czerny , Claudia Sievers , Ulf Diederichsen , Ronald Frank , Christiane Stahl-Hennig , Mark Brönstrup , Hans-Joachim Fritz

Peptide microarrays coupled to machine learning reveal individual epitopes from human antibody responses with neutralizing capabilities against SARS-CoV-2.

Emerging microbes & infections

Avec: Sven-Kevin Hotop , Susanne Reimering , Aditya Shekhar , Ehsaneddin Asgari , Ulrike Beutling , Christine Dahlke , Anahita Fathi , Fawad Khan , Marc Lütgehetmann , Rico Ballmann , Andreas Gerstner , Werner Tegge , Luka Cicin-Sain , Ursula Bilitewski , Alice C McHardy , Mark Brönstrup

Clostridioides difficile Modifies its Aromatic Compound Metabolism in Response to Amidochelocardin-Induced Membrane Stress.

mSphere

Avec: Madita Brauer , Sven-Kevin Hotop , Martina Wurster , Jennifer Herrmann , Marcus Miethke , Rabea Schlüter , Silvia Dittmann , Daniela Zühlke , Mark Brönstrup , Michael Lalk , Rolf Müller , Susanne Sievers , Jörg Bernhardt , Katharina Riedel

Diagnosing Zika virus infection against a background of other flaviviruses: Studies in high resolution serological analysis.

Scientific reports

Avec: Sören Hansen , Sven-Kevin Hotop , Oumar Faye , Oumar Ndiaye , Susanne Böhlken-Fascher , Rodrigo Pessôa , Frank Hufert , Christiane Stahl-Hennig , Ronald Frank , Claus-Peter Czerny , Jonas Schmidt-Chanasit , Sabri S Sanabani , Amadou A Sall , Matthias Niedrig , Mark Brönstrup , Hans-Joachim Fritz , Ahmed Abd El Wahed

Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis.

EBioMedicine

Avec: Katja Becker , Sha Cao , Anna Nilsson , Maria Erlandsson , Sven-Kevin Hotop , Janis Kuka , Jon Hansen , Klara Haldimann , Solveiga Grinberga , Talia Berruga-Fernández , Douglas L Huseby , Reza Shariatgorji , Evelina Lindmark , Björn Platzack , Erik C Böttger , David Crich , Lena E Friberg , Carina Vingsbo Lundberg , Diarmaid Hughes , Mark Brönstrup , Per E Andrén , Edgars Liepinsh , Sven N Hobbie

Antibacterial activity of xylose-derived LpxC inhibitors - Synthesis, biological evaluation and molecular docking studies.

Bioorganic chemistry

Avec: Alexander Dreger , Katharina Hoff , Oriana Agoglitta , Sven-Kevin Hotop , Mark Brönstrup , Peter Heisig , Johannes Kirchmair , Ralph Holl

Species-Specific Conservation of Linear Antigenic Sites on Vaccinia Virus A27 Protein Homologs of Orthopoxviruses.

Viruses

Avec: Henrike P Ahsendorf , Li L Gan , Kamal H Eltom , Ahmed Abd El Wahed , Sven-Kevin Hotop , Rachel L Roper , Ulrike Beutling , Mark Broenstrup , Christiane Stahl-Hennig , Ludwig E Hoelzle , Claus-Peter Czerny

Characterisation of an Anti-Vaccinia Virus F13 Single Chain Fragment Variable from a Human Anti-Vaccinia Virus-Specific Recombinant Immunoglobulin Library.

Viruses

Avec: Henrike P Ahsendorf , Ulrike S Diesterbeck , Sven-Kevin Hotop , Michael Winkler , Mark Brönstrup , Claus-Peter Czerny

Synthesis, biological evaluation, and molecular docking studies of aldotetronic acid-based LpxC inhibitors.

Bioorganic chemistry

Avec: Stefan Wimmer , Katharina Hoff , Benedikt Martin , Martin Grewer , Laura Denni , Raquel Lascorz Massanet , Maria Valeria Raimondi , Emre F Bülbül , Jelena Melesina , Sven-Kevin Hotop , Jörg Haupenthal , Holger Rohde , Peter Heisig , Anna K H Hirsch , Mark Brönstrup , Wolfgang Sippl , Ralph Holl

Establishment of an In Bacterio Assay for the Assessment of Carbon Storage Regulator A (CsrA) Inhibitors.

Chembiochem : a European journal of chemical biology

Avec: Yingwen Wu , Ben G E Zoller , Mohamed Ashraf Mostafa Kamal , Sven-Kevin Hotop , Claus-Michael Lehr , Mark Brönstrup , Petra Dersch , Martin Empting

Labyrinthopeptins Exert Broad-Spectrum Antiviral Activity through Lipid-Binding-Mediated Virolysis.

Journal of virology

Avec: Hans Prochnow , Katharina Rox , N V Suryanarayana Birudukota , Loreen Weichert , Sven-Kevin Hotop , Philipp Klahn , Kathrin Mohr , Sergej Franz , Dominic H Banda , Sebastian Blockus , Janine Schreiber , Sibylle Haid , Merel Oeyen , Javier P Martinez , Roderich D Süssmuth , Joachim Wink , Andreas Meyerhans , Christine Goffinet , Martin Messerle , Thomas F Schulz , Andrea Kröger , Dominique Schols , Thomas Pietschmann , Mark Brönstrup

ORFeome Phage Display Reveals a Major Immunogenic Epitope on the S2 Subdomain of SARS-CoV-2 Spike Protein.

Viruses

Avec: Rico Ballmann , Sven-Kevin Hotop , Federico Bertoglio , Stephan Steinke , Philip Alexander Heine , M Zeeshan Chaudhry , Dieter Jahn , Boas Pucker , Fausto Baldanti , Antonio Piralla , Maren Schubert , Luka Čičin-Šain , Mark Brönstrup , Michael Hust , Stefan Dübel

Detection of bornavirus-reactive antibodies and BoDV-1 RNA only in encephalitis patients from virus endemic areas: a comparative serological and molecular sensitivity, specificity, predictive value, and disease duration correlation study.

Infection

Avec: Petra Allartz , Sven-Kevin Hotop , Birgit Muntau , Alexander Schlaphof , Corinna Thomé-Bolduan , Martin Gabriel , Nadine Petersen , Maren Lintzel , Christoph Behrens , Petra Eggert , Kirsten Pörtner , Johann Steiner , Mark Brönstrup , Dennis Tappe

Subcellular Quantification of Uptake in Gram-Negative Bacteria.

Analytical chemistry

Avec: Hans Prochnow , Verena Fetz , Sven-Kevin Hotop , Mariel A García-Rivera , Axel Heumann , Mark Brönstrup

Antibiotic Conjugates with an Artificial MECAM-Based Siderophore Are Potent Agents against Gram-Positive and Gram-Negative Bacterial Pathogens.

Journal of medicinal chemistry

Avec: Lukas Pinkert , Yi-Hui Lai , Carsten Peukert , Sven-Kevin Hotop , Bianka Karge , Lara Marie Schulze , Jörg Grunenberg , Mark Brönstrup

Moonlighting chaperone activity of the enzyme PqsE contributes to RhlR-controlled virulence of Pseudomonas aeruginosa.

Nature communications

Avec: Sebastian Roman Borgert , Steffi Henke , Florian Witzgall , Stefan Schmelz , Susanne Zur Lage , Sven-Kevin Hotop , Steffi Stephen , Dennis Lübken , Jonas Krüger , Nicolas Oswaldo Gomez , Marco van Ham , Lothar Jänsch , Markus Kalesse , Andreas Pich , Mark Brönstrup , Susanne Häussler , Wulf Blankenfeldt

Synthesis and Characterization of DOTAM-Based Sideromycins for Bacterial Imaging and Antimicrobial Therapy.

ACS infectious diseases

Avec: Carsten Peukert , Katharina Rox , Bianka Karge , Sven-Kevin Hotop , Mark Brönstrup

A Targeted Click-to-Release Activation of the Last-Resort Antibiotic Colistin Reduces its Renal Cell Toxicity.

Angewandte Chemie (International ed. in English)

Avec: Jiraborrirak Charoenpattarapreeda , Werner Tegge , Chunfa Xu , Kirsten Harmrolfs , Bettina Hinkelmann , Hannah Wullenkord , Sven-Kevin Hotop , Ulrike Beutling , Katharina Rox , Mark Broenstrup

Réseau de co-auteurs

Mark Brönstrup 16 collaborations

Ulrike Beutling 4 collaborations

Ahmed Abd El Wahed 3 collaborations

Christiane Stahl-Hennig 3 collaborations

Claus-Peter Czerny 3 collaborations

Katharina Rox 3 collaborations

Ronald Frank 2 collaborations

Hans-Joachim Fritz 2 collaborations

Rico Ballmann 2 collaborations

Werner Tegge 2 collaborations

Katharina Hoff 2 collaborations

Peter Heisig 2 collaborations

Ralph Holl 2 collaborations

Henrike P Ahsendorf 2 collaborations

Mark Broenstrup 2 collaborations

Hans Prochnow 2 collaborations

Carsten Peukert 2 collaborations

Bianka Karge 2 collaborations

Florian Czerny 1 collaboration

Claudia Sievers 1 collaboration

Ulf Diederichsen 1 collaboration

Susanne Reimering 1 collaboration

Aditya Shekhar 1 collaboration

Ehsaneddin Asgari 1 collaboration

Christine Dahlke 1 collaboration

Anahita Fathi 1 collaboration

Fawad Khan 1 collaboration

Marc Lütgehetmann 1 collaboration

Andreas Gerstner 1 collaboration

Luka Cicin-Sain 1 collaboration

Ursula Bilitewski 1 collaboration

Alice C McHardy 1 collaboration

Madita Brauer 1 collaboration

Martina Wurster 1 collaboration

Jennifer Herrmann 1 collaboration

Marcus Miethke 1 collaboration

Rabea Schlüter 1 collaboration

Silvia Dittmann 1 collaboration

Daniela Zühlke 1 collaboration

Michael Lalk 1 collaboration

Rolf Müller 1 collaboration

Susanne Sievers 1 collaboration

Jörg Bernhardt 1 collaboration

Katharina Riedel 1 collaboration

Sören Hansen 1 collaboration

Oumar Faye 1 collaboration

Oumar Ndiaye 1 collaboration

Susanne Böhlken-Fascher 1 collaboration

Rodrigo Pessôa 1 collaboration

Frank Hufert 1 collaboration

Jonas Schmidt-Chanasit 1 collaboration

Sabri S Sanabani 1 collaboration

Amadou A Sall 1 collaboration

Matthias Niedrig 1 collaboration

Katja Becker 1 collaboration

Sha Cao 1 collaboration

Anna Nilsson 1 collaboration

Maria Erlandsson 1 collaboration

Janis Kuka 1 collaboration

Jon Hansen 1 collaboration

Klara Haldimann 1 collaboration

Solveiga Grinberga 1 collaboration

Talia Berruga-Fernández 1 collaboration

Douglas L Huseby 1 collaboration

Reza Shariatgorji 1 collaboration

Evelina Lindmark 1 collaboration

Björn Platzack 1 collaboration

Erik C Böttger 1 collaboration

David Crich 1 collaboration

Lena E Friberg 1 collaboration

Carina Vingsbo Lundberg 1 collaboration

Diarmaid Hughes 1 collaboration

Per E Andrén 1 collaboration

Edgars Liepinsh 1 collaboration

Sven N Hobbie 1 collaboration

Alexander Dreger 1 collaboration

Oriana Agoglitta 1 collaboration

Johannes Kirchmair 1 collaboration

Li L Gan 1 collaboration

Kamal H Eltom 1 collaboration

Rachel L Roper 1 collaboration

Ludwig E Hoelzle 1 collaboration

Ulrike S Diesterbeck 1 collaboration

Michael Winkler 1 collaboration

Stefan Wimmer 1 collaboration

Benedikt Martin 1 collaboration

Martin Grewer 1 collaboration

Laura Denni 1 collaboration

Raquel Lascorz Massanet 1 collaboration

Maria Valeria Raimondi 1 collaboration

Emre F Bülbül 1 collaboration

Jelena Melesina 1 collaboration

Jörg Haupenthal 1 collaboration

Holger Rohde 1 collaboration

Anna K H Hirsch 1 collaboration

Wolfgang Sippl 1 collaboration

Yingwen Wu 1 collaboration

Ben G E Zoller 1 collaboration

Mohamed Ashraf Mostafa Kamal 1 collaboration

Claus-Michael Lehr 1 collaboration

Petra Dersch 1 collaboration

Martin Empting 1 collaboration

N V Suryanarayana Birudukota 1 collaboration

Loreen Weichert 1 collaboration

Philipp Klahn 1 collaboration

Kathrin Mohr 1 collaboration

Sergej Franz 1 collaboration

Dominic H Banda 1 collaboration

Sebastian Blockus 1 collaboration

Janine Schreiber 1 collaboration

Sibylle Haid 1 collaboration

Merel Oeyen 1 collaboration

Javier P Martinez 1 collaboration

Roderich D Süssmuth 1 collaboration

Joachim Wink 1 collaboration

Andreas Meyerhans 1 collaboration

Christine Goffinet 1 collaboration

Martin Messerle 1 collaboration

Thomas F Schulz 1 collaboration

Andrea Kröger 1 collaboration

Dominique Schols 1 collaboration

Thomas Pietschmann 1 collaboration

Federico Bertoglio 1 collaboration

Stephan Steinke 1 collaboration

Philip Alexander Heine 1 collaboration

M Zeeshan Chaudhry 1 collaboration

Dieter Jahn 1 collaboration

Boas Pucker 1 collaboration

Fausto Baldanti 1 collaboration

Antonio Piralla 1 collaboration

Maren Schubert 1 collaboration

Luka Čičin-Šain 1 collaboration

Michael Hust 1 collaboration

Stefan Dübel 1 collaboration

Petra Allartz 1 collaboration

Birgit Muntau 1 collaboration

Alexander Schlaphof 1 collaboration

Corinna Thomé-Bolduan 1 collaboration

Martin Gabriel 1 collaboration

Nadine Petersen 1 collaboration

Maren Lintzel 1 collaboration

Christoph Behrens 1 collaboration

Petra Eggert 1 collaboration

Kirsten Pörtner 1 collaboration

Johann Steiner 1 collaboration

Dennis Tappe 1 collaboration

Verena Fetz 1 collaboration

Mariel A García-Rivera 1 collaboration

Axel Heumann 1 collaboration

Lukas Pinkert 1 collaboration

Yi-Hui Lai 1 collaboration

Lara Marie Schulze 1 collaboration

Jörg Grunenberg 1 collaboration

Sebastian Roman Borgert 1 collaboration

Steffi Henke 1 collaboration

Florian Witzgall 1 collaboration

Stefan Schmelz 1 collaboration

Susanne Zur Lage 1 collaboration

Steffi Stephen 1 collaboration

Dennis Lübken 1 collaboration

Jonas Krüger 1 collaboration

Nicolas Oswaldo Gomez 1 collaboration

Marco van Ham 1 collaboration

Lothar Jänsch 1 collaboration

Markus Kalesse 1 collaboration

Andreas Pich 1 collaboration

Susanne Häussler 1 collaboration

Wulf Blankenfeldt 1 collaboration

Jiraborrirak Charoenpattarapreeda 1 collaboration

Chunfa Xu 1 collaboration

Kirsten Harmrolfs 1 collaboration

Bettina Hinkelmann 1 collaboration

Hannah Wullenkord 1 collaboration