Janis Kuka

Affiliations

Latvian Institute of Organic Synthesis, Riga, Latvia.

Publications (15)

Inhibition of CPT2 exacerbates cardiac dysfunction and inflammation in experimental endotoxaemia.

Journal of cellular and molecular medicine

Avec: Marina Makrecka-Kuka , Stanislava Korzh , Melita Videja , Reinis Vilskersts , Eduards Sevostjanovs , Olga Zharkova-Malkova , Pavel Arsenyan , Janis Kuka , Maija Dambrova , Edgars Liepinsh

Rodent Heart and Brain Tissue Preparation for Digital Macro Photography after Ischemia-reperfusion.

Journal of visualized experiments : JoVE

Avec: Edgars Liepinsh , Janis Kuka , Liga Zvejniece , Reinis Vilskersts , Maija Dambrova

Empagliflozin Protects Cardiac Mitochondrial Fatty Acid Metabolism in a Mouse Model of Diet-Induced Lipid Overload.

Cardiovascular drugs and therapy

Avec: Marina Makrecka-Kuka , Stanislava Korzh , Melita Videja , Karlis Vilks , Helena Cirule , Janis Kuka , Maija Dambrova , Edgars Liepinsh

Antibacterial activity of apramycin at acidic pH warrants wide therapeutic window in the treatment of complicated urinary tract infections and acute pyelonephritis.

EBioMedicine

Avec: Katja Becker , Sha Cao , Anna Nilsson , Maria Erlandsson , Sven-Kevin Hotop , Janis Kuka , Jon Hansen , Klara Haldimann , Solveiga Grinberga , Talia Berruga-Fernández , Douglas L Huseby , Reza Shariatgorji , Evelina Lindmark , Björn Platzack , Erik C Böttger , David Crich , Lena E Friberg , Carina Vingsbo Lundberg , Diarmaid Hughes , Mark Brönstrup , Per E Andrén , Edgars Liepinsh , Sven N Hobbie

Low cardiac content of long-chain acylcarnitines in TMLHE knockout mice prevents ischaemia-reperfusion-induced mitochondrial and cardiac damage.

Free radical biology & medicine

Avec: Edgars Liepinsh , Janis Kuka , Karlis Vilks , Baiba Svalbe , Gundega Stelfa , Reinis Vilskersts , Eduards Sevostjanovs , Niks Ricards Goldins , Valerija Groma , Solveiga Grinberga , Mario Plaas , Marina Makrecka-Kuka , Maija Dambrova

ACS medicinal chemistry letters

Avec: Janis Veliks , Melita Videja , Artis Kinens , Raitis Bobrovs , Martins Priede , Janis Kuka

SBT-272 improves TDP-43 pathology in ALS upper motor neurons by modulating mitochondrial integrity, motility, and function.

Neurobiology of disease

Avec: Mukesh Gautam , Barış Genç , Benjamin Helmold , Angela Ahrens , Janis Kuka , Marina Makrecka-Kuka , Aksu Günay , Nuran Koçak , Izaak R Aguilar-Wickings , Dennis Keefe , Guozhu Zheng , Suchitra Swaminathan , Martin Redmon , Hatim A Zariwala , P Hande Özdinler

Metformin decreases bacterial trimethylamine production and trimethylamine N-oxide levels in db/db mice.

Scientific reports

Avec: Janis Kuka , Melita Videja , Marina Makrecka-Kuka , Janis Liepins , Solveiga Grinberga , Eduards Sevostjanovs , Karlis Vilks , Edgars Liepinsh , Maija Dambrova

Imitation of β-lactam binding enables broad-spectrum metallo-β-lactamase inhibitors.

Nature chemistry

Avec: Jürgen Brem , Tharindi Panduwawala , Jon Ulf Hansen , Joanne Hewitt , Edgars Liepins , Pawel Donets , Laura Espina , Alistair J M Farley , Kirill Shubin , Gonzalo Gomez Campillos , Paula Kiuru , Shifali Shishodia , Daniel Krahn , Robert K Leśniak , Juliane Schmidt Adrian , Karina Calvopiña , María-Carmen Turrientes , Madeline E Kavanagh , Dmitrijs Lubriks , Philip Hinchliffe , Gareth W Langley , Ali F Aboklaish , Anders Eneroth , Maria Backlund , Andrei G Baran , Elisabet I Nielsen , Michael Speake , Janis Kuka , John Robinson , Solveiga Grinberga , Lindsay Robinson , Michael A McDonough , Anna M Rydzik , Thomas M Leissing , Juan Carlos Jimenez-Castellanos , Matthew B Avison , Solange Da Silva Pinto , Andrew D Pannifer , Marina Martjuga , Emma Widlake , Martins Priede , Iva Hopkins Navratilova , Marek Gniadkowski , Anna Karin Belfrage , Peter Brandt , Jari Yli-Kauhaluoma , Eric Bacque , Malcolm G P Page , Fredrik Björkling , Jonathan M Tyrrell , James Spencer , Pauline A Lang , Pawel Baranczewski , Rafael Cantón , Stuart P McElroy , Philip S Jones , Fernando Baquero , Edgars Suna , Angus Morrison , Timothy R Walsh , Christopher J Schofield

Pharmacological activation of PPARβ/δ preserves mitochondrial respiratory function in ischemia/reperfusion

Frontiers in endocrinology

Avec: Ioanna Papatheodorou , Marina Makrecka-Kuka , Janis Kuka , Edgars Liepinsh , Maija Dambrova , Antigone Lazou

Acylcarnitines: Nomenclature, Biomarkers, Therapeutic Potential, Drug Targets, and Clinical Trials.

Pharmacological reviews

Avec: Maija Dambrova , Marina Makrecka-Kuka , Janis Kuka , Reinis Vilskersts , Didi Nordberg , Misty M Attwood , Stefan Smesny , Zumrut Duygu Sen , An Chi Guo , Eponine Oler , Siyang Tian , Jiamin Zheng , David S Wishart , Edgars Liepinsh , Helgi B Schiöth

Excretion of the Polymyxin Derivative NAB739 in Murine Urine.

Antibiotics (Basel, Switzerland)

Avec: Martti Vaara , Timo Vaara , Janis Kuka , Eduards Sevostjanovs , Solveiga Grinberga , Maija Dambrova , Edgars Liepinsh

Skull Fractures Induce Neuroinflammation and Worsen Outcomes after Closed Head Injury in Mice.

Journal of neurotrauma

Avec: Liga Zvejniece , Gundega Stelfa , Edijs Vavers , Einars Kupats , Janis Kuka , Baiba Svalbe , Baiba Zvejniece , Christiane Albert-Weissenberger , Anna-Leena Sirén , Nikolaus Plesnila , Maija Dambrova

Inhibition of Fatty Acid Metabolism Increases EPA and DHA Levels and Protects against Myocardial Ischaemia-Reperfusion Injury in Zucker Rats.

Oxidative medicine and cellular longevity

Avec: Janis Kuka , Marina Makrecka-Kuka , Karlis Vilks , Stanislava Korzh , Helena Cirule , Eduards Sevostjanovs , Solveiga Grinberga , Maija Dambrova , Edgars Liepinsh

Synthetic Access to Fluorocyclopropylidenes.

Organic letters

Avec: Renate Melngaile , Melita Videja , Janis Kuka , Artis Kinens , Dzintars Zacs , Janis Veliks

Réseau de co-auteurs

Maija Dambrova 10 collaborations

Edgars Liepinsh 10 collaborations

Marina Makrecka-Kuka 8 collaborations

Solveiga Grinberga 6 collaborations

Melita Videja 5 collaborations

Eduards Sevostjanovs 5 collaborations

Reinis Vilskersts 4 collaborations

Karlis Vilks 4 collaborations

Stanislava Korzh 3 collaborations

Liga Zvejniece 2 collaborations

Helena Cirule 2 collaborations

Baiba Svalbe 2 collaborations

Gundega Stelfa 2 collaborations

Janis Veliks 2 collaborations

Artis Kinens 2 collaborations

Martins Priede 2 collaborations

Olga Zharkova-Malkova 1 collaboration

Pavel Arsenyan 1 collaboration

Katja Becker 1 collaboration

Sha Cao 1 collaboration

Anna Nilsson 1 collaboration

Maria Erlandsson 1 collaboration

Sven-Kevin Hotop 1 collaboration

Jon Hansen 1 collaboration

Klara Haldimann 1 collaboration

Talia Berruga-Fernández 1 collaboration

Douglas L Huseby 1 collaboration

Reza Shariatgorji 1 collaboration

Evelina Lindmark 1 collaboration

Björn Platzack 1 collaboration

Erik C Böttger 1 collaboration

David Crich 1 collaboration

Lena E Friberg 1 collaboration

Carina Vingsbo Lundberg 1 collaboration

Diarmaid Hughes 1 collaboration

Mark Brönstrup 1 collaboration

Per E Andrén 1 collaboration

Sven N Hobbie 1 collaboration

Niks Ricards Goldins 1 collaboration

Valerija Groma 1 collaboration

Mario Plaas 1 collaboration

Raitis Bobrovs 1 collaboration

Mukesh Gautam 1 collaboration

Barış Genç 1 collaboration

Benjamin Helmold 1 collaboration

Angela Ahrens 1 collaboration

Aksu Günay 1 collaboration

Nuran Koçak 1 collaboration

Izaak R Aguilar-Wickings 1 collaboration

Dennis Keefe 1 collaboration

Guozhu Zheng 1 collaboration

Suchitra Swaminathan 1 collaboration

Martin Redmon 1 collaboration

Hatim A Zariwala 1 collaboration

P Hande Özdinler 1 collaboration

Janis Liepins 1 collaboration

Jürgen Brem 1 collaboration

Tharindi Panduwawala 1 collaboration

Jon Ulf Hansen 1 collaboration

Joanne Hewitt 1 collaboration

Edgars Liepins 1 collaboration

Pawel Donets 1 collaboration

Laura Espina 1 collaboration

Alistair J M Farley 1 collaboration

Kirill Shubin 1 collaboration

Gonzalo Gomez Campillos 1 collaboration

Paula Kiuru 1 collaboration

Shifali Shishodia 1 collaboration

Daniel Krahn 1 collaboration

Robert K Leśniak 1 collaboration

Juliane Schmidt Adrian 1 collaboration

Karina Calvopiña 1 collaboration

María-Carmen Turrientes 1 collaboration

Madeline E Kavanagh 1 collaboration

Dmitrijs Lubriks 1 collaboration

Philip Hinchliffe 1 collaboration

Gareth W Langley 1 collaboration

Ali F Aboklaish 1 collaboration

Anders Eneroth 1 collaboration

Maria Backlund 1 collaboration

Andrei G Baran 1 collaboration

Elisabet I Nielsen 1 collaboration

Michael Speake 1 collaboration

John Robinson 1 collaboration

Lindsay Robinson 1 collaboration

Michael A McDonough 1 collaboration

Anna M Rydzik 1 collaboration

Thomas M Leissing 1 collaboration

Juan Carlos Jimenez-Castellanos 1 collaboration

Matthew B Avison 1 collaboration

Solange Da Silva Pinto 1 collaboration

Andrew D Pannifer 1 collaboration

Marina Martjuga 1 collaboration

Emma Widlake 1 collaboration

Iva Hopkins Navratilova 1 collaboration

Marek Gniadkowski 1 collaboration

Anna Karin Belfrage 1 collaboration

Peter Brandt 1 collaboration

Jari Yli-Kauhaluoma 1 collaboration

Eric Bacque 1 collaboration

Malcolm G P Page 1 collaboration

Fredrik Björkling 1 collaboration

Jonathan M Tyrrell 1 collaboration

James Spencer 1 collaboration

Pauline A Lang 1 collaboration

Pawel Baranczewski 1 collaboration

Rafael Cantón 1 collaboration

Stuart P McElroy 1 collaboration

Philip S Jones 1 collaboration

Fernando Baquero 1 collaboration

Edgars Suna 1 collaboration

Angus Morrison 1 collaboration

Timothy R Walsh 1 collaboration

Christopher J Schofield 1 collaboration

Ioanna Papatheodorou 1 collaboration

Antigone Lazou 1 collaboration

Didi Nordberg 1 collaboration

Misty M Attwood 1 collaboration

Stefan Smesny 1 collaboration

Zumrut Duygu Sen 1 collaboration

An Chi Guo 1 collaboration

Eponine Oler 1 collaboration

Siyang Tian 1 collaboration

Jiamin Zheng 1 collaboration

David S Wishart 1 collaboration

Helgi B Schiöth 1 collaboration

Martti Vaara 1 collaboration

Timo Vaara 1 collaboration

Edijs Vavers 1 collaboration

Einars Kupats 1 collaboration

Baiba Zvejniece 1 collaboration

Christiane Albert-Weissenberger 1 collaboration

Anna-Leena Sirén 1 collaboration

Nikolaus Plesnila 1 collaboration

Renate Melngaile 1 collaboration

Dzintars Zacs 1 collaboration