Thomas Sommermann

Affiliations

Immune Regulation and Cancer, Max-Delbrück-Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany.

ORCID: 0000-0003-2899-0256

Publications (11)

Precise CRISPR-Cas9 gene repair in autologous memory T cells to treat familial hemophagocytic lymphohistiocytosis.

Science immunology

Avec: Xun Li , Tristan Wirtz , Timm Weber , Mikhail Lebedin , Elijah D Lowenstein , Thomas Sommermann , Andreas Zach , Tomoharu Yasuda , Kathrin de la Rosa , Van Trung Chu , Johannes H Schulte , Ingo Müller , Christine Kocks , Klaus Rajewsky

Functional interplay of Epstein-Barr virus oncoproteins in a mouse model of B cell lymphomagenesis.

Proceedings of the National Academy of Sciences of the United States of America

Avec: Thomas Sommermann , Tomoharu Yasuda , Jonathan Ronen , Tristan Wirtz , Timm Weber , Ulrike Sack , Rebecca Caeser , Jingwei Zhang , Xun Li , Van Trung Chu , Anna Jauch , Kristian Unger , Daniel J Hodson , Altuna Akalin , Klaus Rajewsky

Human T

Nature immunology

Avec: Ying-Yin Chao , Alisa Puhach , David Frieser , Mahima Arunkumar , Laurens Lehner , Thomas Seeholzer , Albert Garcia-Lopez , Marlot van der Wal , Silvia Fibi-Smetana , Axel Dietschmann , Thomas Sommermann , Tamara Ćiković , Leila Taher , Mark S Gresnigt , Sebastiaan J Vastert , Femke van Wijk , Gianni Panagiotou , Daniel Krappmann , Olaf Groß , Christina E Zielinski

In vivo CRISPR/Cas9-mediated screen reveals a critical function of TFDP1 and E2F4 transcription factors in hematopoiesis.

Leukemia

Avec: Ngoc Tung Tran , Robin Graf , Ernesto Acevedo-Ochoa , Janine Trombke , Timm Weber , Thomas Sommermann , Claudia Salomon , Ralf Kühn , Klaus Rajewsky , Van Trung Chu

Bacteria modulate microalgal aging physiology through the induction of extracellular vesicle production to remove harmful metabolites.

Nature microbiology

Avec: Yun Deng , Ruyi Yu , Veit Grabe , Thomas Sommermann , Markus Werner , Marine Vallet , Christian Zerfaß , Oliver Werz , Georg Pohnert

Epstein-Barr virus-driven B cell lymphoma mediated by a direct LMP1-TRAF6 complex.

Nature communications

Avec: Fabian Giehler , Michael S Ostertag , Thomas Sommermann , Daniel Weidl , Kai R Sterz , Helmut Kutz , Andreas Moosmann , Stephan M Feller , Arie Geerlof , Brigitte Biesinger , Grzegorz M Popowicz , Johannes Kirchmair , Arnd Kieser

Epstein-Barr-Virus-Induced One-Carbon Metabolism Drives B Cell Transformation.

Cell metabolism

Avec: Liang Wei Wang , Hongying Shen , Luis Nobre , Ina Ersing , Joao A Paulo , Stephen Trudeau , Zhonghao Wang , Nicholas A Smith , Yijie Ma , Bryn Reinstadler , Jason Nomburg , Thomas Sommermann , Ellen Cahir-McFarland , Steven P Gygi , Vamsi K Mootha , Michael P Weekes , Benjamin E Gewurz

Efficient CRISPR/Cas9-Mediated Gene Knockin in Mouse Hematopoietic Stem and Progenitor Cells.

Cell reports

Avec: Ngoc Tung Tran , Thomas Sommermann , Robin Graf , Janine Trombke , Jenniffer Pempe , Kerstin Petsch , Ralf Kühn , Klaus Rajewsky , Van Trung Chu

B-Cell-Specific Myd88 L252P Expression Causes a Premalignant Gammopathy Resembling IgM MGUS.

Frontiers in immunology

Avec: Kristin Schmidt , Ulrike Sack , Robin Graf , Wiebke Winkler , Oliver Popp , Philipp Mertins , Thomas Sommermann , Christine Kocks , Klaus Rajewsky

LMP1 and EBNA2 constitute a minimal set of EBV genes for transformation of human B cells.

Frontiers in immunology

Avec: Jingwei Zhang , Thomas Sommermann , Xun Li , Lutz Gieselmann , Kathrin de la Rosa , Maria Stecklum , Florian Klein , Christine Kocks , Klaus Rajewsky

An integrated cellular and molecular model of gastric neuroendocrine cancer evolution highlights therapeutic targets.

Cancer cell

Avec: Joscha Griger , Sebastian A Widholz , Moritz Jesinghaus , Niklas de Andrade Krätzig , Sebastian Lange , Thomas Engleitner , Juan José Montero , Ekaterina Zhigalova , Rupert Öllinger , Veveeyan Suresh , Wiebke Winkler , Svenja Lier , Olga Baranov , Riccardo Trozzo , Najib Ben Khaled , Shounak Chakraborty , Jiakun Yu , Björn Konukiewitz , Katja Steiger , Nicole Pfarr , Ashish Rajput , David Sailer , Gisela Keller , Peter Schirmacher , Christoph Röcken , Klaus W Fagerstedt , Julia Mayerle , Marc Schmidt-Supprian , Günter Schneider , Wilko Weichert , Dinis P Calado , Thomas Sommermann , Günter Klöppel , Klaus Rajewsky , Dieter Saur , Roland Rad

Réseau de co-auteurs

Klaus Rajewsky 7 collaborations

Van Trung Chu 4 collaborations

Xun Li 3 collaborations

Timm Weber 3 collaborations

Christine Kocks 3 collaborations

Robin Graf 3 collaborations

Tristan Wirtz 2 collaborations

Tomoharu Yasuda 2 collaborations

Kathrin de la Rosa 2 collaborations

Ulrike Sack 2 collaborations

Jingwei Zhang 2 collaborations

Ngoc Tung Tran 2 collaborations

Janine Trombke 2 collaborations

Ralf Kühn 2 collaborations

Wiebke Winkler 2 collaborations

Mikhail Lebedin 1 collaboration

Elijah D Lowenstein 1 collaboration

Andreas Zach 1 collaboration

Johannes H Schulte 1 collaboration

Ingo Müller 1 collaboration

Jonathan Ronen 1 collaboration

Rebecca Caeser 1 collaboration

Anna Jauch 1 collaboration

Kristian Unger 1 collaboration

Daniel J Hodson 1 collaboration

Altuna Akalin 1 collaboration

Ying-Yin Chao 1 collaboration

Alisa Puhach 1 collaboration

David Frieser 1 collaboration

Mahima Arunkumar 1 collaboration

Laurens Lehner 1 collaboration

Thomas Seeholzer 1 collaboration

Albert Garcia-Lopez 1 collaboration

Marlot van der Wal 1 collaboration

Silvia Fibi-Smetana 1 collaboration

Axel Dietschmann 1 collaboration

Tamara Ćiković 1 collaboration

Leila Taher 1 collaboration

Mark S Gresnigt 1 collaboration

Sebastiaan J Vastert 1 collaboration

Femke van Wijk 1 collaboration

Gianni Panagiotou 1 collaboration

Daniel Krappmann 1 collaboration

Olaf Groß 1 collaboration

Christina E Zielinski 1 collaboration

Ernesto Acevedo-Ochoa 1 collaboration

Claudia Salomon 1 collaboration

Yun Deng 1 collaboration

Ruyi Yu 1 collaboration

Veit Grabe 1 collaboration

Markus Werner 1 collaboration

Marine Vallet 1 collaboration

Christian Zerfaß 1 collaboration

Oliver Werz 1 collaboration

Georg Pohnert 1 collaboration

Fabian Giehler 1 collaboration

Michael S Ostertag 1 collaboration

Daniel Weidl 1 collaboration

Kai R Sterz 1 collaboration

Helmut Kutz 1 collaboration

Andreas Moosmann 1 collaboration

Stephan M Feller 1 collaboration

Arie Geerlof 1 collaboration

Brigitte Biesinger 1 collaboration

Grzegorz M Popowicz 1 collaboration

Johannes Kirchmair 1 collaboration

Arnd Kieser 1 collaboration

Liang Wei Wang 1 collaboration

Hongying Shen 1 collaboration

Luis Nobre 1 collaboration

Ina Ersing 1 collaboration

Joao A Paulo 1 collaboration

Stephen Trudeau 1 collaboration

Zhonghao Wang 1 collaboration

Nicholas A Smith 1 collaboration

Yijie Ma 1 collaboration

Bryn Reinstadler 1 collaboration

Jason Nomburg 1 collaboration

Ellen Cahir-McFarland 1 collaboration

Steven P Gygi 1 collaboration

Vamsi K Mootha 1 collaboration

Michael P Weekes 1 collaboration

Benjamin E Gewurz 1 collaboration

Jenniffer Pempe 1 collaboration

Kerstin Petsch 1 collaboration

Kristin Schmidt 1 collaboration

Oliver Popp 1 collaboration

Philipp Mertins 1 collaboration

Lutz Gieselmann 1 collaboration

Maria Stecklum 1 collaboration

Florian Klein 1 collaboration

Joscha Griger 1 collaboration

Sebastian A Widholz 1 collaboration

Moritz Jesinghaus 1 collaboration

Niklas de Andrade Krätzig 1 collaboration

Sebastian Lange 1 collaboration

Thomas Engleitner 1 collaboration

Juan José Montero 1 collaboration

Ekaterina Zhigalova 1 collaboration

Rupert Öllinger 1 collaboration

Veveeyan Suresh 1 collaboration

Svenja Lier 1 collaboration

Olga Baranov 1 collaboration

Riccardo Trozzo 1 collaboration

Najib Ben Khaled 1 collaboration

Shounak Chakraborty 1 collaboration

Jiakun Yu 1 collaboration

Björn Konukiewitz 1 collaboration

Katja Steiger 1 collaboration

Nicole Pfarr 1 collaboration

Ashish Rajput 1 collaboration

David Sailer 1 collaboration

Gisela Keller 1 collaboration

Peter Schirmacher 1 collaboration

Christoph Röcken 1 collaboration

Klaus W Fagerstedt 1 collaboration

Julia Mayerle 1 collaboration

Marc Schmidt-Supprian 1 collaboration

Günter Schneider 1 collaboration

Wilko Weichert 1 collaboration

Dinis P Calado 1 collaboration

Günter Klöppel 1 collaboration

Dieter Saur 1 collaboration

Roland Rad 1 collaboration