Timothy S Strutzenberg

Affiliations

Department of Molecular Medicine, The Scripps Research Institute, Jupiter, FL 33458, USA.

ORCID: 0000-0003-0598-534X

Publications (14)

Cryo-EM structure of human GPR158 receptor coupled to the RGS7-Gβ5 signaling complex.

Science (New York, N.Y.)

Avec: Dipak N Patil , Shikha Singh , Thibaut Laboute , Timothy S Strutzenberg , Xingyu Qiu , Di Wu , Scott J Novick , Carol V Robinson , Patrick R Griffin , John F Hunt , Tina Izard , Appu K Singh , Kirill A Martemyanov

A Bifunctional NAD

ACS chemical biology

Avec: Albert T Lam , Xiao-Nan Zhang , Valentine V Courouble , Timothy S Strutzenberg , Hua Pei , Bangyan L Stiles , Stan G Louie , Patrick R Griffin , Yong Zhang

HDX-MS reveals structural determinants for RORγ hyperactivation by synthetic agonists.

eLife

Avec: Timothy S Strutzenberg , Ruben D Garcia-Ordonez , Scott J Novick , HaJeung Park , Mi Ra Chang , Christelle Doebellin , Yuanjun He , Rémi Patouret , Theodore M Kamenecka , Patrick R Griffin

Mechanisms of HIV-1 integrase resistance to dolutegravir and potent inhibition of drug-resistant variants.

Science advances

Avec: Min Li , Dario Oliveira Passos , Zelin Shan , Steven J Smith , Qinfang Sun , Avik Biswas , Indrani Choudhuri , Timothy S Strutzenberg , Allan Haldane , Nanjie Deng , Zhaoyang Li , Xue Zhi Zhao , Lorenzo Briganti , Mamuka Kvaratskhelia , Terrence R Burke , Ronald M Levy , Stephen H Hughes , Robert Craigie , Dmitry Lyumkis

Unique Polypharmacology Nuclear Receptor Modulator Blocks Inflammatory Signaling Pathways.

ACS chemical biology

Avec: Mi Ra Chang , Anthony Ciesla , Timothy S Strutzenberg , Scott J Novick , Yuanjun He , Ruben D Garcia-Ordonez , Rebecca L Frkic , John B Bruning , Theodore M Kamenecka , Patrick R Griffin

Conformational Changes of RORγ During Response Element Recognition and Coregulator Engagement.

Journal of molecular biology

Avec: Timothy S Strutzenberg , Yingmin Zhu , Scott J Novick , Ruben D Garcia-Ordonez , Christelle Doebelin , Yuanjun He , Mi Ra Chang , Theodore M Kamenecka , Dean P Edwards , Patrick R Griffin

Discovery of an NAD

Chemical science

Avec: Xiao-Nan Zhang , Albert T Lam , Qinqin Cheng , Valentine V Courouble , Timothy S Strutzenberg , Jiawei Li , Yiling Wang , Hua Pei , Bangyan L Stiles , Stan G Louie , Patrick R Griffin , Yong Zhang

Single-Particle Cryo-EM Data Collection with Stage Tilt using Leginon.

Journal of visualized experiments : JoVE

Avec: Sriram Aiyer , Timothy S Strutzenberg , Marianne E Bowman , Joseph P Noel , Dmitry Lyumkis

Federating Structural Models and Data: Outcomes from A Workshop on Archiving Integrative Structures.

Structure (London, England : 1993)

Avec: Helen M Berman , Paul D Adams , Alexandre A Bonvin , Stephen K Burley , Bridget Carragher , Wah Chiu , Frank DiMaio , Thomas E Ferrin , Margaret J Gabanyi , Thomas D Goddard , Patrick R Griffin , Juergen Haas , Christian A Hanke , Jeffrey C Hoch , Gerhard Hummer , Genji Kurisu , Catherine L Lawson , Alexander Leitner , John L Markley , Jens Meiler , Gaetano T Montelione , George N Phillips , Thomas Prisner , Juri Rappsilber , David C Schriemer , Torsten Schwede , Claus A M Seidel , Timothy S Strutzenberg , Dmitri I Svergun , Emad Tajkhorshid , Jill Trewhella , Brinda Vallat , Sameer Velankar , Geerten W Vuister , Benjamin Webb , John D Westbrook , Kate L White , Andrej Sali

Comparative Analysis of Cleavage Specificities of Immobilized Porcine Pepsin and Nepenthesin II under Hydrogen/Deuterium Exchange Conditions.

Analytical chemistry

Avec: Jie Zheng , Timothy S Strutzenberg , Adrian Reich , Venkatasubramanian Dharmarajan , Bruce D Pascal , Gogce C Crynen , Scott J Novick , Ruben D Garcia-Ordonez , Patrick R Griffin

Recommendations for performing, interpreting and reporting hydrogen deuterium exchange mass spectrometry (HDX-MS) experiments.

Nature methods

Avec: Glenn R Masson , John E Burke , Natalie G Ahn , Ganesh S Anand , Christoph Borchers , Sébastien Brier , George M Bou-Assaf , John R Engen , S Walter Englander , Johan Faber , Rachel Garlish , Patrick R Griffin , Michael L Gross , Miklos Guttman , Yoshitomo Hamuro , Albert J R Heck , Damian Houde , Roxana E Iacob , Thomas J D Jørgensen , Igor A Kaltashov , Judith P Klinman , Lars Konermann , Petr Man , Leland Mayne , Bruce D Pascal , Dana Reichmann , Mark Skehel , Joost Snijder , Timothy S Strutzenberg , Eric S Underbakke , Cornelia Wagner , Thomas E Wales , Benjamin T Walters , David D Weis , Derek J Wilson , Patrick L Wintrode , Zhongqi Zhang , Jie Zheng , David C Schriemer , Kasper D Rand

Structural basis for heme-dependent NCoR binding to the transcriptional repressor REV-ERBβ.

Science advances

Avec: Sarah A Mosure , Timothy S Strutzenberg , Jinsai Shang , Paola Munoz-Tello , Laura A Solt , Patrick R Griffin , Douglas J Kojetin

One-step construction of circularized nanodiscs using SpyCatcher-SpyTag.

Nature communications

Avec: Shanwen Zhang , Qian Ren , Scott J Novick , Timothy S Strutzenberg , Patrick R Griffin , Huan Bao

Structure of an AMPK complex in an inactive, ATP-bound state.

Science (New York, N.Y.)

Avec: Yan Yan , Somnath Mukherjee , Kaleeckal G Harikumar , Timothy S Strutzenberg , X Edward Zhou , Kelly Suino-Powell , Ting-Hai Xu , Ryan D Sheldon , Jared Lamp , Joseph S Brunzelle , Katarzyna Radziwon , Abigail Ellis , Scott J Novick , Irving E Vega , Russell G Jones , Laurence J Miller , H Eric Xu , Patrick R Griffin , Anthony A Kossiakoff , Karsten Melcher

Réseau de co-auteurs

Patrick R Griffin 12 collaborations

Scott J Novick 7 collaborations

Ruben D Garcia-Ordonez 4 collaborations

Mi Ra Chang 3 collaborations

Yuanjun He 3 collaborations

Theodore M Kamenecka 3 collaborations

Albert T Lam 2 collaborations

Xiao-Nan Zhang 2 collaborations

Valentine V Courouble 2 collaborations

Hua Pei 2 collaborations

Bangyan L Stiles 2 collaborations

Stan G Louie 2 collaborations

Yong Zhang 2 collaborations

Dmitry Lyumkis 2 collaborations

David C Schriemer 2 collaborations

Jie Zheng 2 collaborations

Bruce D Pascal 2 collaborations

Dipak N Patil 1 collaboration

Shikha Singh 1 collaboration

Thibaut Laboute 1 collaboration

Xingyu Qiu 1 collaboration

Di Wu 1 collaboration

Carol V Robinson 1 collaboration

John F Hunt 1 collaboration

Tina Izard 1 collaboration

Appu K Singh 1 collaboration

Kirill A Martemyanov 1 collaboration

HaJeung Park 1 collaboration

Christelle Doebellin 1 collaboration

Rémi Patouret 1 collaboration

Min Li 1 collaboration

Dario Oliveira Passos 1 collaboration

Zelin Shan 1 collaboration

Steven J Smith 1 collaboration

Qinfang Sun 1 collaboration

Avik Biswas 1 collaboration

Indrani Choudhuri 1 collaboration

Allan Haldane 1 collaboration

Nanjie Deng 1 collaboration

Zhaoyang Li 1 collaboration

Xue Zhi Zhao 1 collaboration

Lorenzo Briganti 1 collaboration

Mamuka Kvaratskhelia 1 collaboration

Terrence R Burke 1 collaboration

Ronald M Levy 1 collaboration

Stephen H Hughes 1 collaboration

Robert Craigie 1 collaboration

Anthony Ciesla 1 collaboration

Rebecca L Frkic 1 collaboration

John B Bruning 1 collaboration

Yingmin Zhu 1 collaboration

Christelle Doebelin 1 collaboration

Dean P Edwards 1 collaboration

Qinqin Cheng 1 collaboration

Jiawei Li 1 collaboration

Yiling Wang 1 collaboration

Sriram Aiyer 1 collaboration

Marianne E Bowman 1 collaboration

Joseph P Noel 1 collaboration

Helen M Berman 1 collaboration

Paul D Adams 1 collaboration

Alexandre A Bonvin 1 collaboration

Stephen K Burley 1 collaboration

Bridget Carragher 1 collaboration

Wah Chiu 1 collaboration

Frank DiMaio 1 collaboration

Thomas E Ferrin 1 collaboration

Margaret J Gabanyi 1 collaboration

Thomas D Goddard 1 collaboration

Juergen Haas 1 collaboration

Christian A Hanke 1 collaboration

Jeffrey C Hoch 1 collaboration

Gerhard Hummer 1 collaboration

Genji Kurisu 1 collaboration

Catherine L Lawson 1 collaboration

Alexander Leitner 1 collaboration

John L Markley 1 collaboration

Jens Meiler 1 collaboration

Gaetano T Montelione 1 collaboration

George N Phillips 1 collaboration

Thomas Prisner 1 collaboration

Juri Rappsilber 1 collaboration

Torsten Schwede 1 collaboration

Claus A M Seidel 1 collaboration

Dmitri I Svergun 1 collaboration

Emad Tajkhorshid 1 collaboration

Jill Trewhella 1 collaboration

Brinda Vallat 1 collaboration

Sameer Velankar 1 collaboration

Geerten W Vuister 1 collaboration

Benjamin Webb 1 collaboration

John D Westbrook 1 collaboration

Kate L White 1 collaboration

Andrej Sali 1 collaboration

Adrian Reich 1 collaboration

Venkatasubramanian Dharmarajan 1 collaboration

Gogce C Crynen 1 collaboration

Glenn R Masson 1 collaboration

John E Burke 1 collaboration

Natalie G Ahn 1 collaboration

Ganesh S Anand 1 collaboration

Christoph Borchers 1 collaboration

Sébastien Brier 1 collaboration

George M Bou-Assaf 1 collaboration

John R Engen 1 collaboration

S Walter Englander 1 collaboration

Johan Faber 1 collaboration

Rachel Garlish 1 collaboration

Michael L Gross 1 collaboration

Miklos Guttman 1 collaboration

Yoshitomo Hamuro 1 collaboration

Albert J R Heck 1 collaboration

Damian Houde 1 collaboration

Roxana E Iacob 1 collaboration

Thomas J D Jørgensen 1 collaboration

Igor A Kaltashov 1 collaboration

Judith P Klinman 1 collaboration

Lars Konermann 1 collaboration

Petr Man 1 collaboration

Leland Mayne 1 collaboration

Dana Reichmann 1 collaboration

Mark Skehel 1 collaboration

Joost Snijder 1 collaboration

Eric S Underbakke 1 collaboration

Cornelia Wagner 1 collaboration

Thomas E Wales 1 collaboration

Benjamin T Walters 1 collaboration

David D Weis 1 collaboration

Derek J Wilson 1 collaboration

Patrick L Wintrode 1 collaboration

Zhongqi Zhang 1 collaboration

Kasper D Rand 1 collaboration

Sarah A Mosure 1 collaboration

Jinsai Shang 1 collaboration

Paola Munoz-Tello 1 collaboration

Laura A Solt 1 collaboration

Douglas J Kojetin 1 collaboration

Shanwen Zhang 1 collaboration

Qian Ren 1 collaboration

Huan Bao 1 collaboration

Yan Yan 1 collaboration

Somnath Mukherjee 1 collaboration

Kaleeckal G Harikumar 1 collaboration

X Edward Zhou 1 collaboration

Kelly Suino-Powell 1 collaboration

Ting-Hai Xu 1 collaboration

Ryan D Sheldon 1 collaboration

Jared Lamp 1 collaboration

Joseph S Brunzelle 1 collaboration

Katarzyna Radziwon 1 collaboration

Abigail Ellis 1 collaboration

Irving E Vega 1 collaboration

Russell G Jones 1 collaboration

Laurence J Miller 1 collaboration

H Eric Xu 1 collaboration

Anthony A Kossiakoff 1 collaboration

Karsten Melcher 1 collaboration