La dépression vasculaire peut-elle entraîner des AVC ?
Oui, elle peut augmenter le risque d'accidents vasculaires cérébraux.
Accidents vasculaires cérébrauxDépressionRisques
#3
Y a-t-il un lien avec la démence ?
Oui, la dépression vasculaire peut être un facteur de risque pour la démence.
DémenceDépressionFacteurs de risque
#4
Comment la dépression vasculaire affecte-t-elle la qualité de vie ?
Elle peut réduire la qualité de vie en affectant les relations et les activités quotidiennes.
Qualité de vieDépressionRelations sociales
#5
Les complications sont-elles réversibles ?
Certaines complications peuvent être réversibles avec un traitement approprié.
RéversibilitéTraitementComplications
Facteurs de risque
5
#1
Quels sont les principaux facteurs de risque ?
Les facteurs incluent l'hypertension, le diabète et les antécédents familiaux de dépression.
Facteurs de risqueHypertensionDiabète
#2
L'âge est-il un facteur de risque ?
Oui, le risque augmente avec l'âge, surtout chez les personnes âgées.
ÂgePopulation âgéeDépression
#3
Le sexe influence-t-il le risque ?
Oui, les femmes sont souvent plus touchées par la dépression vasculaire que les hommes.
SexeDépressionGenre
#4
Le mode de vie peut-il affecter le risque ?
Oui, un mode de vie sédentaire et une mauvaise alimentation augmentent le risque.
Mode de vieSédentaritéAlimentation
#5
Les antécédents de dépression augmentent-ils le risque ?
Oui, avoir des antécédents de dépression augmente le risque de dépression vasculaire.
Antécédents médicauxDépressionFacteurs de risque
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"name": "Les médicaments sont-ils toujours nécessaires ?",
"position": 18,
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"@type": "Question",
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"position": 19,
"acceptedAnswer": {
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"text": "Oui, des approches comme l'exercice physique et la méditation peuvent être bénéfiques."
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"@type": "Question",
"name": "Combien de temps dure le traitement ?",
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"@type": "Question",
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"@type": "Question",
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"@type": "Question",
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"position": 26,
"acceptedAnswer": {
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"@type": "Question",
"name": "L'âge est-il un facteur de risque ?",
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"@type": "Question",
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Department of Radiology, Shenzhen Traditional Chinese Medicine Hospital/The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, China.
Department of Neurology and Psychology, Shenzhen Traditional Chinese Medicine Hospital/The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, China.
Department of Radiology, Shenzhen Traditional Chinese Medicine Hospital/The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, China.
Department of Neurology and Psychology, Shenzhen Traditional Chinese Medicine Hospital/The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, China.
Department of Radiology, Shenzhen Traditional Chinese Medicine Hospital/The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, China.
Department of Acupuncture and Moxibustion, Shenzhen Traditional Chinese Medicine Hospital, The Fourth Clinical Medical College, Guangzhou University of Chinese Medicine, Shenzhen, China.
Vascular diseases are associated with significant sequelae and clinical repercussions for the lives of affected patients, which are more serious among the elderly. The consequences of vascular disease...
To determine the prevalence of depression and assess functional capacity in patients with vascular diseases admitted to a Vascular Surgery Service....
This is a descriptive, cross-sectional study, carried out at the Vascular Surgery Service of a tertiary hospital with a non-random sample of patients selected consecutively. The geriatric depression s...
The prevalence of depression in these patients was 60.6%. Associations were observed between depression and consultation with a family doctor in the last 12 months, alcoholism, claudication, diabetes,...
There was a high prevalence of depression in patients with vascular diseases admitted to a vascular surgery service and important reductions in functional capacity in some groups, such as individuals ...
Although older adults with HIV are at high risk for mild neurocognitive disorders, a subset experience successful cognitive aging (SCA). HIV is associated with an increased risk of vascular depression...
136 persons with HIV aged 50 years and older were classified as either SCA+ (n=37) or SCA- (n=99) based on a battery of demographically adjusted neurocognitive tests and self-reported cognitive sympto...
A Cochran-Armitage test revealed a significant additive effect of vascular disease and depression on SCA in this sample of older adults with HIV (...
These data suggest that presence of VasDep may be a barrier to SCA in older adults with HIV disease. Prospective, longitudinal studies with neuroimaging-based operationalizations of VasDep are needed ...
Although older adults with HIV are at high risk for mild neurocognitive disorders, a subset experience successful cognitive aging (SCA). HIV is associated with an increased risk of vascular depression...
Female patients frequently experience worse clinical outcomes than male patients after undergoing vascular surgery procedures. However, it is unclear whether these sex-based disparities also impact me...
We retrospectively analyzed 107 patients (73 males and 34 females) who underwent vascular surgery procedures between January 2016 and April 2023. These patients completed a Patient-Reported Outcome Me...
There was no significant difference between female and male patients among rates of complications, length of hospital stay, or rates of nonhome discharge. However, female sex was associated with signi...
These results suggest that female sex is associated with improved patient-reported measures of depression after undergoing vascular surgery. Clinicians should consider these mental health benefits whe...
Vascular endothelial growth factor (VEGF) is a candidate mediator of blood-brain barrier (BBB) disruption in depression. However, previous studies have mainly focused on peripheral blood VEGF levels, ...
Thirty-five unmedicated patients with MDD and 35 healthy controls (HCs) were enrolled, and plasma ADEVs were isolated from each participant. VEGF levels in ADEVs and glial fibrillary acidic protein (G...
At baseline, MDD patients exhibited significantly increased levels of VEGF in ADEVs and GFAP in plasma. Following four weeks of selective serotonin reuptake inhibitor treatment, these target protein l...
Multiple factors regulate BBB permeability. This study focused solely on VEGF and the sample size for longitudinal analysis was relatively small....
Our study is the first to confirm increased ADEV-derived VEGF levels in patients with MDD, thereby providing preliminary evidence supporting the hypothesis that the BBB is disrupted in depression....
Depression is a significant global health concern, projected to become the leading disease burden. Vascular burden has been implicated in the pathogenesis of depression. Conversely, whether depression...
Utilizing data from the National Health and Nutrition Examination Survey (NHANES), the study included 27,764 participants after exclusions. Depression was assessed using the Patient Health Questionnai...
Individuals with depression exhibited a higher risk of an advanced vascular age over their chronological age. Mendelian randomization analysis indicated a causal relationship between depression and ar...
The study design limits the exploration of the dynamic relationship between changes in vascular age and depression due to the single timepoint measurement....
This study highlights the bidirectional relationship between depression and vascular age. Vascular age is a significant biomarker for the risk and prognosis of depression, while depression may contrib...
This study examined whether C-reactive protein (CRP), a marker of low-grade systemic inflammation, mediates the association between vascular risk factor (VRF) burden and depressive symptoms....
We drew on the prospective design of the UK Biobank to include participants with longitudinal data on VRF burden, CRP, and depressive symptoms. Total, direct, and indirect effects were estimated using...
We analyzed data from 10,470 participants from the UK Biobank (mean age = 56.75 years at baseline). Net of covariates, VRFs at baseline were associated with higher depressive symptoms at follow-up (to...
These results suggest that inflammation-promoting effects of VRFs may contribute to depressive symptoms in mid- and later life. However, the mediating pathway via CRP explains only a small part of the...
Late-life depression and white matter hyperintensities (WMHs) have been linked to increased dementia risk. However, there is a dearth of literature examining these relationships in Black adults. We in...
Secondary data analysis involved 443 Black participants aged 55+ with brain imaging within one year of baseline visit in the National Alzheimer's Coordinating Center (NACC) Uniform Data Set. Chi-squar...
Depression and higher WMH volume were associated with a higher prevalence of dementia. These associations remained after controlling for demographic factors, as well as vascular disease burden. Dement...
Results suggest late-life depression and WMHs have independent and joint relationships with dementia and that Black individuals may be particularly at risk due to these factors....
Vascular depression (VaD) is a depressive disorder closely associated with cerebrovascular disease and vascular risk factors. It remains underestimated owing to challenging diagnostics and limited inf...
Deep profiling of the serum proteome of 35 patients with VaD and 36 controls was performed using liquid chromatography-tandem mass spectrometry (LC-MS/MS). Functional enrichment analysis of the quanti...
There were 29 up-regulated and 31 down-regulated proteins in the VaD group compared to the controls (|log...
This study offers a comprehensive and integrated view of serum proteomics and contributes to a valuable proteomics-based diagnostic model for VaD....
Although depression symptoms are commonly reported in patients with subcortical vascular mild cognitive impairment (svMCI), their impact on brain functions remains largely unknown, with diagnoses main...
In this study, we analyzed resting-state fMRI data from a cohort of 34 svMCI patients, comprising 18 patients with depression symptoms (svMCI+D) and 16 patients without (svMCI-D), along with 34 normal...
The fALFF of the right cerebellum (CERE.R) differed among the svMCI+D, svMCI-D, and NC groups. Specifically, the regional mean fALFF of CERE. R was lower in svMCI-D patients compared to NC but higher ...
The study revealed disruptive effects of cognitive impairment, along with both disruptive and complementary effects of depression symptoms on spontaneous brain activity in svMCI. Moreover, these findi...
