How To Read a Network Meta-analysis.
Network meta-analysis (NMA) expands upon traditional meta-analysis by integrating three or more interventions. This allows comparing interventions using evidence from trials that have compared pairs o...
Benzocycloheptènes : Questions médicales fréquentes
Questions fréquentes et termes MeSH associés
Diagnostic 5
#1
Comment identifier les benzocycloheptènes ?
L'identification se fait par des techniques de spectroscopie et de chromatographie.
#2
Quels tests sont utilisés pour les benzocycloheptènes ?
Des tests de toxicité et d'efficacité sont réalisés en laboratoire.
#3
Les benzocycloheptènes sont-ils détectables dans le sang ?
Oui, ils peuvent être détectés par des analyses spécifiques dans des échantillons biologiques.
#4
Y a-t-il des marqueurs spécifiques pour ces composés ?
Des marqueurs biologiques peuvent indiquer l'exposition à ces composés.
#5
Peut-on utiliser l'imagerie pour les benzocycloheptènes ?
L'imagerie moléculaire peut aider à visualiser leur distribution dans les tissus.
Symptômes 5
#1
Quels sont les effets secondaires des benzocycloheptènes ?
Ils peuvent provoquer des nausées, des vertiges ou des réactions allergiques.
#2
Les benzocycloheptènes causent-ils des douleurs ?
Des douleurs peuvent survenir en cas de toxicité ou d'allergie.
#3
Y a-t-il des symptômes neurologiques associés ?
Oui, des symptômes comme des maux de tête ou des troubles de la coordination peuvent apparaître.
#4
Peut-on observer des symptômes cutanés ?
Des éruptions cutanées peuvent survenir en cas de réaction allergique.
#5
Les benzocycloheptènes affectent-ils le système respiratoire ?
Une exposition excessive peut entraîner des irritations respiratoires.
Prévention 5
#1
Comment prévenir l'exposition aux benzocycloheptènes ?
Utiliser des équipements de protection et suivre les protocoles de sécurité en laboratoire.
#2
Y a-t-il des formations pour manipuler ces composés ?
Oui, des formations spécifiques sont souvent requises pour les chercheurs.
#3
Quels sont les risques en milieu industriel ?
Les travailleurs peuvent être exposés à des niveaux élevés sans protection adéquate.
#4
Des réglementations existent-elles pour leur usage ?
Oui, des réglementations strictes encadrent leur utilisation en laboratoire et en industrie.
#5
Comment évaluer les risques d'exposition ?
Des évaluations de risque doivent être effectuées régulièrement dans les environnements de travail.
Traitements 5
#1
Comment traiter une intoxication aux benzocycloheptènes ?
Le traitement inclut l'élimination de l'exposition et des soins symptomatiques.
#2
Y a-t-il des antidotes pour ces composés ?
Actuellement, il n'existe pas d'antidote spécifique pour les benzocycloheptènes.
#3
Quels médicaments peuvent aider en cas d'allergie ?
Des antihistaminiques peuvent être utilisés pour traiter les réactions allergiques.
#4
Les benzocycloheptènes nécessitent-ils une hospitalisation ?
Une hospitalisation peut être nécessaire en cas de symptômes graves.
#5
Comment gérer les effets à long terme ?
Un suivi médical régulier est recommandé pour surveiller les effets à long terme.
Complications 5
#1
Quelles complications peuvent survenir avec ces composés ?
Des complications comme des lésions organiques peuvent survenir en cas d'exposition prolongée.
#2
Les benzocycloheptènes peuvent-ils causer des cancers ?
Des études suggèrent un potentiel cancérigène, mais des recherches supplémentaires sont nécessaires.
#3
Y a-t-il des effets sur la reproduction ?
Des effets néfastes sur la reproduction ont été observés dans certaines études animales.
#4
Peut-on développer des allergies à long terme ?
Oui, des sensibilisations peuvent se développer avec une exposition répétée.
#5
Les benzocycloheptènes affectent-ils le système immunitaire ?
Une exposition prolongée peut altérer la fonction immunitaire, augmentant les infections.
Facteurs de risque 5
#1
Qui est le plus à risque d'exposition ?
Les travailleurs en laboratoire et en industrie chimique sont les plus exposés.
#2
L'âge influence-t-il la sensibilité ?
Oui, les jeunes et les personnes âgées peuvent être plus sensibles aux effets toxiques.
#3
Y a-t-il des prédispositions génétiques ?
Certaines prédispositions génétiques peuvent augmenter la sensibilité aux toxines.
#4
Les antécédents médicaux jouent-ils un rôle ?
Oui, des antécédents d'allergies ou de maladies respiratoires augmentent le risque.
#5
L'environnement de travail influence-t-il le risque ?
Oui, un environnement de travail mal ventilé augmente le risque d'exposition.
Contenu validé par Dr Olivier Menir
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 08/03/2025
Contenu vérifié selon les dernières recommandations médicales
Sous-catégories
8 au total
└─
Dibenzocycloheptènes
DibenzocycloheptenesD003986 -
D04.615.181.384
└─└─
Amitriptyline
AmitriptylineD000639 -
D04.615.181.384.100
└─└─
Butaclamol
ButaclamolD002069 -
D04.615.181.384.230
└─└─
Cyproheptadine
CyproheptadineD003533 -
D04.615.181.384.340
└─└─
Maléate de dizocilpine
Dizocilpine MaleateD016291 -
D04.615.181.384.380
└─└─
Nortriptyline
NortriptylineD009661 -
D04.615.181.384.535
└─└─
Protriptyline
ProtriptylineD011530 -
D04.615.181.384.650
└─└─└─
Loratadine
LoratadineD017336 -
D04.615.181.384.340.500
Auteurs principaux
Jiatian Li
1 publication dans cette catégorie
Affiliations :
- State Key Laboratory of Luminescent Materials and Devices, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, P.R. China.
Publications dans "Benzocycloheptènes" :
Xiangwen Tan
1 publication dans cette catégorie
Affiliations :
- State Key Laboratory of Luminescent Materials and Devices, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, P.R. China.
Publications dans "Benzocycloheptènes" :
Huanfeng Jiang
1 publication dans cette catégorie
Affiliations :
- State Key Laboratory of Luminescent Materials and Devices, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, P.R. China.
Publications dans "Benzocycloheptènes" :
Wanqing Wu
1 publication dans cette catégorie
Affiliations :
- State Key Laboratory of Luminescent Materials and Devices, School of Chemistry and Chemical Engineering, South China University of Technology, Guangzhou 510641, P.R. China.
Publications dans "Benzocycloheptènes" :
Sources (10000 au total)
Methodological quality of network meta-analysis in dentistry: a meta-research.
This meta-research aimed to provide an overview of the methodological quality and risk of bias of network meta-analyses (NMA) in dentistry. Searches for NMA of randomized clinical trials with clinical...
Effects of non-pharmacological interventions for adults with subjective cognitive decline: a network meta-analysis and component network meta-analysis.
Non-pharmacological interventions have a myriad of available intervention options and contain multiple components. Whether specific components of non-pharmacological interventions or combinations are ... PubMed, Embase, Cochrane, CINAHL, PsycINFO, CENTRAL, Web of Science, and China's two largest databases, CNKI and Wanfang, were searched from inception to 22nd, January 2023. Randomized controlled tria... A total of 39 trials with 2959 patients were included (range of mean ages, 58.79-77.41 years). Resistance exercise might be the optimal intervention for reducing memory complaints in adults with subje... The form of physical activity performed appears to be more beneficial than cognitive interventions in reducing subjective memory complaints for adults with subjective cognitive decline, and this diffe... PROSPERO registry number. CRD42022355363....
Network meta-interpolation: Effect modification adjustment in network meta-analysis using subgroup analyses.
Effect modification (EM) may cause bias in network meta-analysis (NMA). Existing population adjustment NMA methods use individual patient data to adjust for EM but disregard available subgroup informa...
Treatments for alopecia areata: a network meta-analysis.
Alopecia areata is an autoimmune disease leading to nonscarring hair loss on the scalp or body. There are different treatments including immunosuppressants, hair growth stimulants, and contact immunot... To assess the benefits and harms of the treatments for alopecia areata (AA), alopecia totalis (AT), and alopecia universalis (AU) in children and adults.... The Cochrane Skin Specialised Register, CENTRAL, MEDLINE, Embase, ClinicalTrials.gov and WHO ICTRP were searched up to July 2022.... We included randomised controlled trials (RCTs) that evaluated classical immunosuppressants, biologics, small molecule inhibitors, contact immunotherapy, hair growth stimulants, and other therapies in... We used the standard procedures expected by Cochrane including assessment of risks of bias using RoB2 and the certainty of the evidence using GRADE. The primary outcomes were short-term hair regrowth ... We included 63 studies that tested 47 different treatments in 4817 randomised participants. All trials used a parallel-group design except one that used a cross-over design. The mean sample size was 7... We found that treatment with baricitinib results in an increase in short- and long-term hair regrowth compared to placebo. Although we found inconclusive results for the risk of serious adverse effect...
Bias propagation in network meta-analysis models.
Network meta-analysis combines direct and indirect evidence to compare multiple treatments. As direct evidence for one treatment contrast may be indirect evidence for other treatment contrasts, biases...
Does type of funding affect reporting in network meta-analysis? A scoping review of network meta-analyses.
Evidence has shown that private industry-sponsored randomized controlled trials (RCTs) and meta-analyses are more likely to report intervention-favourable results compared with other sources of fundin... To (a) explore the recommendation rate of industry-sponsored NMAs on their company's intervention, and (b) assess reporting in NMAs of pharmacologic interventions according to their funding type.... Design: Scoping review of published NMAs with RCTs.... We used a pre-existing NMA database including 1,144 articles from MEDLINE, EMBASE and Cochrane Database of Systematic Reviews, published between January 2013 and July 2018.... NMAs with transparent funding information and comparing pharmacologic interventions with/without placebo.... We captured whether NMAs recommended their own or another company's intervention, classified NMAs according to their primary outcome findings (i.e., statistical significance and direction of effect), ... We retrieved 658 NMAs, which reported a median of 23 items in the PRISMA-NMA checklist (interquartile range [IQR]: 21-26). NMAs were categorized as 314 publicly-sponsored (PRISMA-NMA median 24.5, IQR ... Differences in completeness of reporting and author characteristics were apparent among NMAs with different types of funding. Publicly-sponsored NMAs had the best reporting and published their finding...
Efficacy of innovative therapies in myasthenia gravis: A systematic review, meta-analysis and network meta-analysis.
Therapy for myasthenia gravis (MG) is undergoing a profound change, with new treatments being tested. These include complement inhibitors and neonatal Fc receptor (FcRn) blockers. The aim of this stud... We assessed statistical heterogeneity across trials based on the Cochrane Q test and I... We observed an overall mean Myasthenia Gravis-Activities of Daily Living scale (MG-ADL) score change of -2.17 points (95% confidence interval [CI] -2.67, -1.67; p < 0.001) as compared to placebo. No s... Anti-complement and FcRn treatments both proved to be effective in MG patients, whereas rituximab did not show a significant benefit for patients. Within the limitations of this meta-analysis, includi...
Effectiveness of aerobic exercise in the prevention and treatment of postpartum depression: Meta-analysis and network meta-analysis.
Aerobic exercise is widely recognized for improving mental health and reducing negative emotions, including anxiety. However, research on its role in preventing and treating postpartum depression (PPD... We conducted a quantitative systematic review of the study in 5 representative databases for the effect of aerobic exercise on PPD. Meta-analysis and network meta-analysis were performed with Review-M... Twenty-six studies with 2,867 participants were eventually included and the efficacy of aerobic exercise in preventing and treating postpartum depression is significant compared to standard care. (MD ... The efficacy of aerobic exercise in preventing and treating postpartum depression is significant compared to standard care, with a greater emphasis on prevention. The optimal prescribed exercise volum...
Antibiotic Prophylaxis in Reduction Mammaplasty: A Network Meta-Analysis.
Mounting evidence suggests that breast reduction surgery displays higher rates of surgical site infections (SSI) than initially presumed. Objective of this network meta-analysis is to evaluate the eff... A network meta-analysis was conducted using a predetermined protocol after searching the electronic databases MEDLINE, Scopus, the Cochrane Library and US National Institutes of Health Ongoing Trials ... A total of 10 studies was included in the analysis involving 1331 patients. All but one study controlled for major risk factors, and no differences were observed in patients' baseline characteristics.... Antibiotics mitigate the SSI rate after breast reduction. This meta-analysis provides an evidence-based strategy to optimize antibiotic administration. Further research is needed though to examine ant... This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Inst...