questionsmedicales.fr
Tissus
Épithélium
Épithélium : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Endoscopie
Imagerie par résonance magnétique
Fonction épithéliale
Tests de sécrétion
Symptômes
5
Allergie
Éruption cutanée
Prévention
5
Hygiène
Alimentation équilibrée
Infection
Hygiène des mains
Protection solaire
Hydratation
Vitamines
Acides gras oméga-3
Allergènes
Antihistaminiques
Traitements
5
Antihistaminiques
Irritation
Chimiothérapie
Radiothérapie
Complications
5
Effets secondaires
Saignement
Facteurs de risque
5
Tabagisme
Exposition au soleil
Vieillissement
Régénération cellulaire
Pollution
Produits chimiques
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"name": "Comment diagnostiquer une maladie épithéliale ?",
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"text": "Le diagnostic se fait par biopsie, examens histologiques et imageries médicales."
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{
"@type": "Question",
"name": "Quels tests sont utilisés pour évaluer l'épithélium ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des tests comme l'endoscopie, l'échographie et l'IRM peuvent être utilisés."
}
},
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"@type": "Question",
"name": "Quels signes indiquent une pathologie épithéliale ?",
"position": 3,
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"text": "Des signes comme des lésions, des ulcérations ou des anomalies de surface peuvent indiquer une pathologie."
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"name": "Comment évaluer la fonction épithéliale ?",
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"@type": "Question",
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"position": 6,
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"@type": "Question",
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"position": 7,
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"@type": "Answer",
"text": "Les infections peuvent se manifester par rougeur, chaleur, gonflement et écoulement."
}
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{
"@type": "Question",
"name": "Quels signes indiquent une irritation épithéliale ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des démangeaisons, des rougeurs et des desquamations peuvent indiquer une irritation."
}
},
{
"@type": "Question",
"name": "Quels symptômes peuvent signaler un cancer épithélial ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des symptômes comme des masses, des changements de couleur ou des saignements inexpliqués."
}
},
{
"@type": "Question",
"name": "Comment se manifeste une allergie épithéliale ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les allergies peuvent provoquer des éruptions cutanées, des démangeaisons et des rougeurs."
}
},
{
"@type": "Question",
"name": "Comment prévenir les maladies épithéliales ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "La prévention passe par une bonne hygiène, une alimentation équilibrée et l'évitement des irritants."
}
},
{
"@type": "Question",
"name": "Quels comportements réduire le risque d'infections épithéliales ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éviter le contact avec des personnes malades et se laver les mains régulièrement."
}
},
{
"@type": "Question",
"name": "Comment protéger l'épithélium de la peau ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Utiliser des crèmes solaires et hydrater régulièrement pour protéger la peau."
}
},
{
"@type": "Question",
"name": "Quels aliments favorisent la santé épithéliale ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les aliments riches en vitamines A, C et E, ainsi que les acides gras oméga-3 sont bénéfiques."
}
},
{
"@type": "Question",
"name": "Comment éviter les allergies épithéliales ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Identifier et éviter les allergènes connus, et utiliser des antihistaminiques préventifs."
}
},
{
"@type": "Question",
"name": "Quels traitements sont disponibles pour les maladies épithéliales ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements incluent médicaments, thérapies topiques et interventions chirurgicales."
}
},
{
"@type": "Question",
"name": "Comment traiter une infection épithéliale ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les infections sont souvent traitées avec des antibiotiques ou des antifongiques."
}
},
{
"@type": "Question",
"name": "Quels soins sont recommandés pour les lésions épithéliales ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les soins incluent nettoyage, désinfection et parfois sutures pour les lésions."
}
},
{
"@type": "Question",
"name": "Comment gérer les symptômes d'irritation épithéliale ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des crèmes apaisantes et des antihistaminiques peuvent aider à soulager l'irritation."
}
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{
"@type": "Question",
"name": "Quels traitements sont efficaces contre le cancer épithélial ?",
"position": 20,
"acceptedAnswer": {
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"text": "Les traitements incluent chirurgie, radiothérapie et chimiothérapie selon le stade."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec les maladies épithéliales ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent infections secondaires, cicatrices et déformations."
}
},
{
"@type": "Question",
"name": "Comment les cancers épithéliaux peuvent-ils évoluer ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent se propager localement ou à distance, entraînant des métastases."
}
},
{
"@type": "Question",
"name": "Quels risques sont associés aux traitements épithéliaux ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les traitements peuvent entraîner des effets secondaires comme des infections ou des saignements."
}
},
{
"@type": "Question",
"name": "Quelles sont les conséquences d'une irritation chronique ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une irritation chronique peut mener à des infections, des lésions et des cancers cutanés."
}
},
{
"@type": "Question",
"name": "Comment les maladies épithéliales affectent-elles la qualité de vie ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent causer douleur, inconfort et altérer les activités quotidiennes."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque pour les maladies épithéliales ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent le tabagisme, l'exposition au soleil et les infections virales."
}
},
{
"@type": "Question",
"name": "Comment l'âge influence-t-il les maladies épithéliales ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le vieillissement peut réduire la régénération cellulaire et augmenter le risque de maladies."
}
},
{
"@type": "Question",
"name": "Quel rôle joue la génétique dans les maladies épithéliales ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des prédispositions génétiques peuvent augmenter le risque de cancers épithéliaux."
}
},
{
"@type": "Question",
"name": "Comment le mode de vie affecte-t-il la santé épithéliale ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un mode de vie malsain, comme une mauvaise alimentation, peut aggraver les maladies épithéliales."
}
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{
"@type": "Question",
"name": "Quels environnements augmentent le risque d'irritation épithéliale ?",
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"acceptedAnswer": {
"@type": "Answer",
"text": "Les environnements pollués ou irritants, comme les produits chimiques, augmentent le risque."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 12/05/2025
Contenu vérifié selon les dernières recommandations médicales
2 publications dans cette catégorie
Affiliations :
Department of Genetics and Center for Molecular Studies in Liver and Digestive Diseases, Perelman School of Medicine, University of Pennsylvania, 12-126 Smilow Center for Translational Research, 3400 Civic Center Boulevard, Philadelphia, PA, 19104-5156, USA.
Publications dans "Épithélium" :
2 publications dans cette catégorie
Affiliations :
Department of Genetics and Center for Molecular Studies in Liver and Digestive Diseases, Perelman School of Medicine, University of Pennsylvania, 12-126 Smilow Center for Translational Research, 3400 Civic Center Boulevard, Philadelphia, PA, 19104-5156, USA.
Publications dans "Épithélium" :
2 publications dans cette catégorie
Affiliations :
Department of Genetics and Center for Molecular Studies in Liver and Digestive Diseases, Perelman School of Medicine, University of Pennsylvania, 12-126 Smilow Center for Translational Research, 3400 Civic Center Boulevard, Philadelphia, PA, 19104-5156, USA.
Publications dans "Épithélium" :
2 publications dans cette catégorie
Affiliations :
Columbia Stem Cell Initiative, Division of Digestive and Liver Diseases, Department of Medicine, Columbia Center for Human Development, Columbia University Irving Medical Center, New York, New York.
Department of Genetics & Development, Columbia University Irving Medical Center, New York, New York.
Publications dans "Épithélium" :
2 publications dans cette catégorie
Affiliations :
Department of Systems Biology, Columbia University Irving Medical Center, New York, New York.
Department of Biochemistry & Molecular Biophysics, Columbia University Irving Medical Center, New York, New York.
Publications dans "Épithélium" :
2 publications dans cette catégorie
Affiliations :
Columbia Stem Cell Initiative, Division of Digestive and Liver Diseases, Department of Medicine, Columbia Center for Human Development, Columbia University Irving Medical Center, New York, New York.
Department of Genetics & Development, Columbia University Irving Medical Center, New York, New York.
Publications dans "Épithélium" :
2 publications dans cette catégorie
Affiliations :
Department of Developmental, Molecular & Chemical Biology, Tufts University School of Medicine, Boston, Massachusetts 02111, jim.schwob@tufts.edu.
Publications dans "Épithélium" :
2 publications dans cette catégorie
Affiliations :
Division of Plastic and Reconstructive Surgery, Department of Surgery, School of Medicine, Stanford University, Palo Alto, CA, USA.
Publications dans "Épithélium" :
2 publications dans cette catégorie
Affiliations :
Division of Plastic and Reconstructive Surgery, Department of Surgery, School of Medicine, Stanford University, Palo Alto, CA, USA.
Department of Stomatology, The Affiliated Hospital of Qingdao University, Qingdao, China.
Publications dans "Épithélium" :
2 publications dans cette catégorie
Affiliations :
Division of Plastic and Reconstructive Surgery, Department of Surgery, School of Medicine, Stanford University, Palo Alto, CA, USA.
Publications dans "Épithélium" :
1 publication dans cette catégorie
Affiliations :
Department of Anatomy, University of California, San Francisco, San Francisco, United States.
Department of OB/GYN-RS, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, United States.
Publications dans "Épithélium" :
1 publication dans cette catégorie
Affiliations :
Department of Anatomy, University of California, San Francisco, San Francisco, United States.
Department of OB/GYN-RS, Center for Reproductive Sciences, University of California, San Francisco, San Francisco, United States.
Publications dans "Épithélium" :
1 publication dans cette catégorie
Affiliations :
Laboratory of Neurobiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 49 Convent Drive, Bethesda, MD 20892, USA mayorova@wsbs-msu.ru tatiana.mayorova@nih.gov.
Publications dans "Épithélium" :
1 publication dans cette catégorie
Affiliations :
Central Microscopy Facility, Marine Biological Laboratory, 7 MBL Street, Woods Hole, MA 02543, USA.
Publications dans "Épithélium" :
1 publication dans cette catégorie
Affiliations :
Laboratory of Neurobiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 49 Convent Drive, Bethesda, MD 20892, USA.
Publications dans "Épithélium" :
1 publication dans cette catégorie
Affiliations :
Laboratory of Neurobiology, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 49 Convent Drive, Bethesda, MD 20892, USA.
Publications dans "Épithélium" :
1 publication dans cette catégorie
Affiliations :
Light Imaging Facility, National Institute of Neurological Disorders and Stroke, National Institutes of Health, 35 Convent Drive, Bethesda, MD 20892, USA.
Publications dans "Épithélium" :
1 publication dans cette catégorie
Affiliations :
Department of Mathematics, University College London , Gower Street, London WC1E 6BT , UK.
Publications dans "Épithélium" :
1 publication dans cette catégorie
Affiliations :
Department of Mathematics, University College London , Gower Street, London WC1E 6BT , UK.
Publications dans "Épithélium" :
1 publication dans cette catégorie
Affiliations :
Lung Biology Center, University of California San Francisco, San Francisco, CA, United States.
Publications dans "Épithélium" :
To compare the ability of immunohistochemistry (IHC), multiparameter flow cytometry (MFC) and fluorescence in situ hybridisation (FISH) to detect clonal plasma cells. We also attempted to outline a te...
A retrospective review was performed on 278 CD138+sorted FISH studies from November 2019 to December 2020 along with their concurrent IHC and MFC results. A p value was computed using McNemar's test f...
Using the Mc Nemar's test for paired data, CD138+sorted FISH studies achieved the highest proportion of positive results and was significantly greater than MFC (63% vs 53%, p=0.01). FISH had more posi...
While CD138+sorted FISH is primarily used for prognostication, it may be employed as a single test for detection and monitoring clonality in certain scenarios. Further studies are needed to monitor th...
Plasma cell vulvitis is a rare inflammatory disorder of the vulva with an unknown aetiology, characterised by mucosal inflammation. It commonly manifests as pain, itching, dyspareunia, and dysuria and...
case report; immunosuppressant; platelet-rich plasma; vulvitis....
The evaluation of plasma cell (PC) compartment is influenced by the quality of bone marrow aspirate (BMA). Herein, we evaluated the impact of sequence of pull on quality of clinical assessment in plas...
Histomorphology along with smears from first pull and second pull BMA and flow cytometric immunophenotyping (FCMI) data from second pull aspirate were evaluated for cellularity and PC%....
Of the 484 samples, BMA smears were adequate in 87.4% of first pull (median PC = 7%; IQR = 2-25%) and 51.2% of second pull samples (median PC = 2%; IQR = 0.5-12%; p < 0.001). Recovery of PC was least ...
First pull BMA smears were of superior quality but inadequate in one-tenth of samples. Second pull smears underreported PC% and recovery of PC compartment was poorest on FCMI. Concurrent bone marrow b...
Next-generation sequencing (NGS) detects somatic mutations in a high proportion of plasma cell dyscrasias (PCD), but is currently not integrated into diagnostic routine. We correlated NGS data with de...
Of the 90 patients the diagnoses comprised multiple myeloma (n = 77), MGUS (n = 7), AL-amyloidosis (n = 4) or solitary plasmocytoma (n = 2). The NGS panel included eight genes CCND1, DIS3, EGR1, FAM46...
Mutations were detected in 64/90 (71%) of cases. KRAS (29%), NRAS (16%) and DIS3 (16%) were most frequently mutated. At least one mutation/sample corresponded to a higher degree of BM involvement with...
The probability of detecting a mutation by NGS in the BM was highest in samples with > 10% clonal PC by MFC, or > 20% PC by BMC/ BMH. We propose further evaluation of these thresholds as a practical c...
Plasma cells (PCs) are essential for the quality and longevity of protective immunity. The canonical humoral response to vaccination involves induction of germinal centers in lymph nodes followed by m...
Plasma cell gingivitis (PCG) is an inflammatory condition that affects the gingival mucosa of the oral cavity. It is characterized by polyclonal dense plasma cell infiltrate in the connective tissue. ...
Primary plasma cell leukemia (PCL) is the most aggressive monoclonal gammopathy. It was formerly characterized by ≥ 20% circulating plasma cells (CTCs) until 2021, when this threshold was decreased to...
We assessed the levels of CTCs by multiparameter flow cytometry in 395 patients with newly diagnosed transplant-ineligible MM to establish a cutoff for CTCs that identifies the patients with ultra-hig...
Newly diagnosed transplant-ineligible patients with MM with 2%-20% CTCs had significantly shorter progression-free survival (3.1...
Our study uncovers that ≥ 2% CTCs is a biomarker of hidden primary PCL and supports the assessment of CTCs by flow cytometry during the diagnostic workup of MM....
Autoantibody (autoAbs) production in osteoarthritis (OA), coupled with evidence of disturbed B-cell homoeostasis, suggest a potential role for B-cells in OA. B-cells can differentiate with T-cell help...
B-cells were isolated from OA and HC. Standardised in vitro models of B-cell differentiation were used comparing T-dep (CD40 (cluster of differentiation-40/BCR (B-cell receptor)-ligation) versus TLR-d...
Compared to HC, circulating OA B-cells showed an overall more mature phenotype. The gene expression profile of synovial OA B-cells resembled that of PCs. Circulating B-cells differentiated under both ...
Our findings suggest that OA B-cells present an altered capacity for proliferation and differentiation while remaining able to produce antibodies, notably in synovium. These findings may partly contri...
A recent study shows that the SNARE protein Sec22b plays a key role in antibody-secreting plasma cell accrual. Without Sec22b, antibody titres were diminished, and plasma cells rare to undetectable. T...
In recent decades, our understanding of periodontitis has evolved from that based on a gross/histologic level to one on a cellular/molecular level. Previous landscape studies have explored molecular s...