Quels types de modifications subissent les protéines dans le Golgi ?
Les protéines peuvent subir des glycosylations, des phosphorylations et des sulfatations.
GlycosylationPhosphorylationProtéines
#4
L'appareil de Golgi est-il impliqué dans la sécrétion cellulaire ?
Oui, il joue un rôle clé dans la sécrétion des protéines vers l'extérieur de la cellule.
Sécrétion cellulaireProtéinesAppareil de Golgi
#5
Quelles sont les structures associées à l'appareil de Golgi ?
Il est composé de citernes aplaties et de vésicules de transport.
VésiculesCisternesAppareil de Golgi
{
"@context": "https://schema.org",
"@graph": [
{
"@type": "MedicalWebPage",
"name": "Appareil de Golgi : Questions médicales les plus fréquentes",
"headline": "Appareil de Golgi : Comprendre les symptômes, diagnostics et traitements",
"description": "Guide complet et accessible sur les Appareil de Golgi : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.",
"datePublished": "2024-01-29",
"dateModified": "2025-04-23",
"inLanguage": "fr",
"medicalAudience": [
{
"@type": "MedicalAudience",
"name": "Grand public",
"audienceType": "Patient",
"healthCondition": {
"@type": "MedicalCondition",
"name": "Appareil de Golgi"
},
"suggestedMinAge": 18,
"suggestedGender": "unisex"
},
{
"@type": "MedicalAudience",
"name": "Médecins",
"audienceType": "Physician",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "France"
}
},
{
"@type": "MedicalAudience",
"name": "Chercheurs",
"audienceType": "Researcher",
"geographicArea": {
"@type": "AdministrativeArea",
"name": "International"
}
}
],
"reviewedBy": {
"@type": "Person",
"name": "Dr Olivier Menir",
"jobTitle": "Expert en Médecine",
"description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale",
"url": "/static/pages/docteur-olivier-menir.html",
"alumniOf": {
"@type": "EducationalOrganization",
"name": "Université Paris Descartes"
}
},
"isPartOf": {
"@type": "MedicalWebPage",
"name": "Organites",
"url": "https://questionsmedicales.fr/mesh/D015388",
"about": {
"@type": "MedicalCondition",
"name": "Organites",
"code": {
"@type": "MedicalCode",
"code": "D015388",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "A11.284.430.214.190.875"
}
}
},
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Réseau trans-golgien",
"alternateName": "trans-Golgi Network",
"url": "https://questionsmedicales.fr/mesh/D021601",
"about": {
"@type": "MedicalCondition",
"name": "Réseau trans-golgien",
"code": {
"@type": "MedicalCode",
"code": "D021601",
"codingSystem": "MeSH"
},
"identifier": {
"@type": "PropertyValue",
"propertyID": "MeSH Tree",
"value": "A11.284.430.214.190.875.336.850"
}
}
}
],
"about": {
"@type": "MedicalCondition",
"name": "Appareil de Golgi",
"alternateName": "Golgi Apparatus",
"code": {
"@type": "MedicalCode",
"code": "D006056",
"codingSystem": "MeSH"
}
},
"author": [
{
"@type": "Person",
"name": "Akihiko Nakano",
"url": "https://questionsmedicales.fr/author/Akihiko%20Nakano",
"affiliation": {
"@type": "Organization",
"name": "RIKEN Center for Advanced Photonics, Wako, Japan."
}
},
{
"@type": "Person",
"name": "Christian Makhoul",
"url": "https://questionsmedicales.fr/author/Christian%20Makhoul",
"affiliation": {
"@type": "Organization",
"name": "The Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia."
}
},
{
"@type": "Person",
"name": "Paul A Gleeson",
"url": "https://questionsmedicales.fr/author/Paul%20A%20Gleeson",
"affiliation": {
"@type": "Organization",
"name": "The Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia."
}
},
{
"@type": "Person",
"name": "Doris Hellerschmied",
"url": "https://questionsmedicales.fr/author/Doris%20Hellerschmied",
"affiliation": {
"@type": "Organization",
"name": "Faculty of Biology, Center of Medical Biotechnology, University Duisburg-Essen, Essen, Germany. doris.hellerschmied@uni-due.de."
}
},
{
"@type": "Person",
"name": "Yanzhuang Wang",
"url": "https://questionsmedicales.fr/author/Yanzhuang%20Wang",
"affiliation": {
"@type": "Organization",
"name": "Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI, United States."
}
}
],
"citation": [
{
"@type": "ScholarlyArticle",
"name": "Lipoplasty in the Overweight Patient.",
"datePublished": "2023-08-08",
"url": "https://questionsmedicales.fr/article/37945074",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.cps.2023.06.010"
}
},
{
"@type": "ScholarlyArticle",
"name": "Boys with overweight status lagged behind girls with overweight status in reading: evidence from mendelian randomization.",
"datePublished": "2023-05-06",
"url": "https://questionsmedicales.fr/article/37156340",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.jclinepi.2023.05.001"
}
},
{
"@type": "ScholarlyArticle",
"name": "Overweight grandsons and grandfathers' starvation exposure.",
"datePublished": "2023-07-15",
"url": "https://questionsmedicales.fr/article/37541079",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.jhealeco.2023.102796"
}
},
{
"@type": "ScholarlyArticle",
"name": "Homocysteine concentrations in overweight children and adolescents.",
"datePublished": "2023-01-30",
"url": "https://questionsmedicales.fr/article/36722654",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1590/1806-9282.20220991"
}
},
{
"@type": "ScholarlyArticle",
"name": "Cancers attributable to overweight and obesity in Italy.",
"datePublished": "2023-10-11",
"url": "https://questionsmedicales.fr/article/37832242",
"identifier": {
"@type": "PropertyValue",
"propertyID": "DOI",
"value": "10.1016/j.canep.2023.102468"
}
}
],
"breadcrumb": {
"@type": "BreadcrumbList",
"itemListElement": [
{
"@type": "ListItem",
"position": 1,
"name": "questionsmedicales.fr",
"item": "https://questionsmedicales.fr"
},
{
"@type": "ListItem",
"position": 2,
"name": "Cellules",
"item": "https://questionsmedicales.fr/mesh/D002477"
},
{
"@type": "ListItem",
"position": 3,
"name": "Structures cellulaires",
"item": "https://questionsmedicales.fr/mesh/D022082"
},
{
"@type": "ListItem",
"position": 4,
"name": "Espace intracellulaire",
"item": "https://questionsmedicales.fr/mesh/D042541"
},
{
"@type": "ListItem",
"position": 5,
"name": "Cytoplasme",
"item": "https://questionsmedicales.fr/mesh/D003593"
},
{
"@type": "ListItem",
"position": 6,
"name": "Structures cytoplasmiques",
"item": "https://questionsmedicales.fr/mesh/D022083"
},
{
"@type": "ListItem",
"position": 7,
"name": "Organites",
"item": "https://questionsmedicales.fr/mesh/D015388"
},
{
"@type": "ListItem",
"position": 8,
"name": "Appareil de Golgi",
"item": "https://questionsmedicales.fr/mesh/D006056"
}
]
}
},
{
"@type": "MedicalWebPage",
"name": "Article complet : Appareil de Golgi - Questions et réponses",
"headline": "Questions et réponses médicales fréquentes sur Appareil de Golgi",
"description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.",
"datePublished": "2025-05-17",
"inLanguage": "fr",
"hasPart": [
{
"@type": "MedicalWebPage",
"name": "Recherche",
"headline": "Recherche sur Appareil de Golgi",
"description": "Quelles techniques sont utilisées pour étudier le Golgi ?\nQuels sont les modèles animaux pour étudier le Golgi ?\nComment les chercheurs étudient-ils les maladies du Golgi ?\nY a-t-il des traitements ciblant l'appareil de Golgi ?\nQuels sont les défis de la recherche sur le Golgi ?",
"url": "https://questionsmedicales.fr/mesh/D006056?mesh_terms=Overweight#section-recherche"
},
{
"@type": "MedicalWebPage",
"name": "Éducation",
"headline": "Éducation sur Appareil de Golgi",
"description": "Comment enseigner le rôle du Golgi en biologie ?\nQuels sont les concepts clés à enseigner sur le Golgi ?\nY a-t-il des ressources en ligne sur le Golgi ?\nComment les étudiants peuvent-ils visualiser le Golgi ?\nQuels sont les outils pédagogiques pour le Golgi ?",
"url": "https://questionsmedicales.fr/mesh/D006056?mesh_terms=Overweight#section-éducation"
},
{
"@type": "MedicalWebPage",
"name": "Pathologies",
"headline": "Pathologies sur Appareil de Golgi",
"description": "Quelles maladies sont liées à des dysfonctionnements du Golgi ?\nComment les maladies du Golgi affectent-elles les cellules ?\nLes maladies génétiques peuvent-elles affecter l'appareil de Golgi ?\nQuels sont les symptômes d'une dysfonction de l'appareil de Golgi ?\nL'appareil de Golgi est-il impliqué dans le cancer ?",
"url": "https://questionsmedicales.fr/mesh/D006056?mesh_terms=Overweight#section-pathologies"
},
{
"@type": "MedicalWebPage",
"name": "Fonctionnalité",
"headline": "Fonctionnalité sur Appareil de Golgi",
"description": "Quel est le rôle principal de l'appareil de Golgi ?\nComment l'appareil de Golgi interagit-il avec le réticulum endoplasmique ?\nQuels types de modifications subissent les protéines dans le Golgi ?\nL'appareil de Golgi est-il impliqué dans la sécrétion cellulaire ?\nQuelles sont les structures associées à l'appareil de Golgi ?",
"url": "https://questionsmedicales.fr/mesh/D006056?mesh_terms=Overweight#section-fonctionnalité"
}
]
},
{
"@type": "FAQPage",
"mainEntity": [
{
"@type": "Question",
"name": "Quelles techniques sont utilisées pour étudier le Golgi ?",
"position": 1,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des techniques comme la microscopie électronique et la biologie moléculaire sont utilisées."
}
},
{
"@type": "Question",
"name": "Quels sont les modèles animaux pour étudier le Golgi ?",
"position": 2,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les souris et les drosophiles sont souvent utilisés pour étudier les fonctions du Golgi."
}
},
{
"@type": "Question",
"name": "Comment les chercheurs étudient-ils les maladies du Golgi ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils utilisent des modèles cellulaires et des études génétiques pour comprendre les mécanismes."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements ciblant l'appareil de Golgi ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des recherches sont en cours pour développer des thérapies ciblant les dysfonctionnements du Golgi."
}
},
{
"@type": "Question",
"name": "Quels sont les défis de la recherche sur le Golgi ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les défis incluent la complexité de ses fonctions et la diversité des maladies associées."
}
},
{
"@type": "Question",
"name": "Comment enseigner le rôle du Golgi en biologie ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Utiliser des modèles 3D et des animations pour illustrer ses fonctions et interactions."
}
},
{
"@type": "Question",
"name": "Quels sont les concepts clés à enseigner sur le Golgi ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les concepts de modification des protéines, de transport et de pathologies associées."
}
},
{
"@type": "Question",
"name": "Y a-t-il des ressources en ligne sur le Golgi ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des sites éducatifs et des vidéos explicatives sont disponibles en ligne."
}
},
{
"@type": "Question",
"name": "Comment les étudiants peuvent-ils visualiser le Golgi ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Ils peuvent utiliser des logiciels de modélisation et des images de microscopie."
}
},
{
"@type": "Question",
"name": "Quels sont les outils pédagogiques pour le Golgi ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des manuels, des vidéos et des simulations interactives sont des outils efficaces."
}
},
{
"@type": "Question",
"name": "Quelles maladies sont liées à des dysfonctionnements du Golgi ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des maladies comme le syndrome de Golgi et certaines maladies neurodégénératives."
}
},
{
"@type": "Question",
"name": "Comment les maladies du Golgi affectent-elles les cellules ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elles peuvent entraîner des défauts de sécrétion et des accumulations de protéines."
}
},
{
"@type": "Question",
"name": "Les maladies génétiques peuvent-elles affecter l'appareil de Golgi ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certaines mutations génétiques peuvent perturber sa fonction."
}
},
{
"@type": "Question",
"name": "Quels sont les symptômes d'une dysfonction de l'appareil de Golgi ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les symptômes peuvent inclure des troubles métaboliques et des anomalies cellulaires."
}
},
{
"@type": "Question",
"name": "L'appareil de Golgi est-il impliqué dans le cancer ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des altérations de son fonctionnement peuvent contribuer à la progression tumorale."
}
},
{
"@type": "Question",
"name": "Quel est le rôle principal de l'appareil de Golgi ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il modifie, trie et emballe les protéines et lipides pour leur transport."
}
},
{
"@type": "Question",
"name": "Comment l'appareil de Golgi interagit-il avec le réticulum endoplasmique ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il reçoit des protéines du réticulum endoplasmique pour les modifier et les expédier."
}
},
{
"@type": "Question",
"name": "Quels types de modifications subissent les protéines dans le Golgi ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les protéines peuvent subir des glycosylations, des phosphorylations et des sulfatations."
}
},
{
"@type": "Question",
"name": "L'appareil de Golgi est-il impliqué dans la sécrétion cellulaire ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, il joue un rôle clé dans la sécrétion des protéines vers l'extérieur de la cellule."
}
},
{
"@type": "Question",
"name": "Quelles sont les structures associées à l'appareil de Golgi ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il est composé de citernes aplaties et de vésicules de transport."
}
}
]
}
]
}
The Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia.
The Department of Biochemistry and Molecular Biology, Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Melbourne, VIC, Australia.
Institut Curie, PSL Research University, CNRS, UMR 144, 26 rue d'Ulm F-75005, Paris, France; Sorbonne Université, UPMC University Paris 06, CNRS, UMR 144, 26 rue d'Ulm F-75005, Paris, France.
The practice of large volume liposuction, when executed by board-certified plastic surgeons using a variety of energy-assisted liposuction devices, has been substantiated as a secure procedure, yieldi...
We investigated the relationship between childhood weight status and academic achievement across sexes and different school subjects in Norway....
We used data from the Norwegian Mother, Father and Child Cohort Study (MoBa), which includes genetic data (N = 13,648, 8-year-old children). We employed within-family mendelian randomization, using a ...
Contrary to most previous findings, we observed that overweight status (including obesity) has more detrimental effects on reading achievement in boys than in girls; the test scores of boys with overw...
Previous obesity prevention studies have mainly targeted girls, based on the assumption that the obesity penalty is greater for girls. Our findings highlight that particular attention to boys with ove...
Much of the increase in the prevalence of overweight and obesity has been in developing countries with a history of famines and malnutrition. This paper is the first to examine overweight among adult ...
The aim of this study was to describe homocysteine concentrations in overweight and obese children and adolescents and relate them to blood pressure levels, renal function, and insulin resistance....
This is a cross-sectional and observational study with 64 overweight children and adolescents (mean age: 11.6±3.5 years) in outpatient follow-up. The following parameters were evaluated: body mass ind...
The mean body mass index z-score was 2.9±1.1. The mean homocysteine concentrations were 8.6±2.2 μmol/L (10th and 90th percentiles: 6.6 and 11.2 μmol/L, respectively), with no difference when compared ...
Homocysteine concentrations in overweight children and adolescents (mean 8.6±2.2 μmol/L) were not associated with body mass index z-score, blood pressure, renal function, and insulin resistance....
Overweight and obesity are associated with multiple cancers. We quantified the burden of cancer attributable to overweight and obesity in Italy....
We estimated sex- and cancer site-specific population attributable fractions (PAFs) combining relative risks (from recent meta-analyses) with national obesity prevalence data (from a large sample surv...
3.6% of cancers in men and 4.0% in women in Italy were attributable to overweight and obesity, corresponding, respectively, to over 6900 and 7200 diagnoses in 2020. Attributable deaths were over 3600 ...
The cancer burden associated with overweight and obesity in Italy is considerable, but smaller compared to other high income countries, likely because of the lower prevalence of overweight and obesity...
This study aimed to investigate the association between overweight and obesity in postmenopausal women and different aspects related to health such as quality of life, physical activity, sleep quality...
An observational cross-sectional study was carried out during 2021-2022 in Spain in postmenopausal women. Health-related quality of life was assessed using the 12-item short-form survey (SF-12). The P...
A total of 395 postmenopausal women participated: 64.6% (...
Obesity in postmenopausal women negatively affects perceived quality of life, sleep quality, physical activity, the development of cardiovascular problems and pelvic floor-related problems....
Overweight in youth is influenced by genes and environment. Gene-environment interaction (G×E) has been demonstrated in twin studies and recent developments in genetics allow for studying G×E using in...
Latent class growth models of overweight were fitted using data from the TRacking Adolescents' Individual Lives Survey (n = 2720). A polygenic score for body mass index (BMI) was derived using summary...
A three-class model of developmental pathways of overweight fitted the data best ("non-overweight", "adolescent-onset overweight", and "persistent overweight"). The polygenic score for BMI and socioec...
Higher genetic predisposition increased the risk of developing overweight during adolescence and young adulthood and was associated with an earlier age at onset. We did not find that genetic predispos...
Obesity is a major health problem worldwide as it can lead to high blood pressure, heart disease, stroke, diabetes, and insulin resistance. The prevalence of overweight and obesity is increasing world...
To assess the effects of calcium supplementation on weight loss in individuals living with overweight or obesity....
We searched CENTRAL, MEDLINE, Embase, LILACS (Latin American and Caribbean Health Science Information database), and two clinical trials registries. The date of the last search of all databases (excep...
We included randomised controlled trials evaluating the effect of calcium in participants with overweight or obesity of any age or gender. We excluded studies in participants with absorption problems....
We used standard methodological procedures expected by Cochrane. Our primary outcomes were body weight, health-related quality of life, and adverse events. Our secondary outcomes were anthropometric m...
We found 18 studies that evaluated the effect of calcium compared to placebo or control, with a total of 1873 randomised participants (950 participants in the calcium supplementation groups and 923 in...
Calcium supplementation for eight weeks to 24 months may result in little to no difference in body weight in people with overweight or obesity. The current evidence is of low certainty, due to concern...
To evaluate whether a fish oil and/or probiotics intervention in pregnant women with overweight or obesity would influence the tendency of their 24-month-old children to become overweight and alter th...
Women (n = 439) were double-blindly randomized into 4 intervention groups: fish oil+placebo, probiotics+placebo, probiotics+fish oil, and placebo+placebo (fish oil: 1.9 g docosahexaenoic acid and 0.22...
Probiotics+placebo [weight-for-height% adj. Odds ratio (OR) = 0.36, 95% confidence interval (CI) = 0.14-0.95] and probiotics+fish oil [weight-for-age standard deviation score (SD-score) adj. OR = 0.22...
The administration of probiotics solely and in combination with fish oil during pregnancy to women with overweight or obesity lowered the overweight odds of their 24-month-old children....
People living with HIV have greater diabetes (T2DM) than the general population despite lower prevalence of overweight/obesity. Both insulin resistance (IR), a T2DM precursor, and HIV are independentl...
To study the association between inflammation and IR in non-overweight and overweight people living with HIV....
In a cohort of adult people living with HIV with undetectable viral load in Pune, India, we measured fasting insulin, glucose, and 9 inflammatory markers. IR was defined as HOMA-IR ≥2, and non-overwei...
Of 288 participants, 66% (n = 189) were non-overweight. Among non-overweight, prevalence of IR was 34% (n = 65). Each doubling of MCP-1 and leptin was associated with IR on univariate analysis (preval...
One in 3 non-overweight people living with HIV in India with controlled viremia have IR. Leptin was associated with IR among non-overweight people living with HIV and may provide insight into the path...