Titre : Hydralazine

Hydralazine : Questions médicales fréquentes

Nom anglais: Hydralazine

Descriptor UI: D006830

Tree Number: D03.383.710.605.500

Questions fréquentes et termes MeSH associés

Diagnostic 2

#1

Comment l'hydralazine est-elle utilisée dans le diagnostic ?

Elle est utilisée pour évaluer la réponse du patient à un traitement antihypertenseur.
Hypertension Antihypertenseurs
#2

Quels tests sont nécessaires avant de prescrire l'hydralazine ?

Des tests de pression artérielle et des analyses sanguines pour évaluer la fonction cardiaque.
Pression artérielle Tests de laboratoire

Symptômes 2

#1

Quels sont les effets secondaires courants de l'hydralazine ?

Les effets secondaires incluent des maux de tête, des palpitations et des éruptions cutanées.
Effets secondaires Maux de tête
#2

L'hydralazine peut-elle provoquer des symptômes allergiques ?

Oui, des réactions allergiques comme des démangeaisons ou un gonflement peuvent survenir.
Réactions allergiques Démangeaisons

Prévention 2

#1

L'hydralazine peut-elle prévenir des maladies cardiaques ?

Elle aide à contrôler l'hypertension, réduisant ainsi le risque de maladies cardiaques.
Maladies cardiaques Prévention
#2

Quelles mesures doivent être prises lors de l'utilisation d'hydralazine ?

Surveiller régulièrement la pression artérielle et signaler tout effet indésirable.
Surveillance Effets indésirables

Traitements 2

#1

Comment l'hydralazine est-elle administrée ?

Elle est généralement administrée par voie orale sous forme de comprimés ou par injection.
Voie orale Injections
#2

Quelle est la posologie standard de l'hydralazine ?

La posologie initiale est souvent de 10 mg à 25 mg, ajustée selon la réponse du patient.
Posologie Ajustement de dose

Complications 2

#1

Quelles complications peuvent survenir avec l'hydralazine ?

Des complications comme la tachycardie ou la rétention hydrique peuvent se produire.
Tachycardie Rétention hydrique
#2

L'hydralazine peut-elle causer des problèmes rénaux ?

Dans de rares cas, elle peut affecter la fonction rénale, nécessitant une surveillance.
Fonction rénale Surveillance

Facteurs de risque 2

#1

Qui devrait éviter l'hydralazine ?

Les patients avec des antécédents de lupus ou de maladies cardiaques doivent être prudents.
Lupus Maladies cardiaques
#2

Quels médicaments interagissent avec l'hydralazine ?

Des médicaments comme les diurétiques et les bêta-bloquants peuvent interagir.
Interactions médicamenteuses Diurétiques
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Dr Olivier Menir

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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale

Validation scientifique effectuée le 02/07/2026

Contenu vérifié selon les dernières recommandations médicales

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Sous-catégories

1 au total
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Dihydralazine

Dihydralazine D004078 - D03.383.710.605.500.250

Auteurs principaux

Mrigendra B Karmacharya

3 publications dans cette catégorie

Affiliations :
  • Ultrasound Research Laboratory, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 3620 Hamilton Walk, Philadelphia, PA, 19104, USA.
Publications dans "Hydralazine" :

Laith R Sultan

3 publications dans cette catégorie

Affiliations :
  • Ultrasound Research Laboratory, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 3620 Hamilton Walk, Philadelphia, PA, 19104, USA.
Publications dans "Hydralazine" :

Chandra M Sehgal

3 publications dans cette catégorie

Affiliations :
  • Ultrasound Research Laboratory, Department of Radiology, Perelman School of Medicine, University of Pennsylvania, 3620 Hamilton Walk, Philadelphia, PA, 19104, USA. Chandra.Sehgal@pennmedicine.upenn.edu.
Publications dans "Hydralazine" :

Nair Lopes

2 publications dans cette catégorie

Affiliations :
  • Cancer Biology and Epigenetics Group, Research Center of IPO Porto (CI-IPOP)/RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
Publications dans "Hydralazine" :

Mariana Brütt Pacheco

2 publications dans cette catégorie

Affiliations :
  • Cancer Biology and Epigenetics Group, Research Center of IPO Porto (CI-IPOP)/RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
Publications dans "Hydralazine" :

Margareta P Correia

2 publications dans cette catégorie

Affiliations :
  • Cancer Biology and Epigenetics Group, Research Center of IPO Porto (CI-IPOP)/RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
  • Department of Pathology and Molecular Immunology, School of Medicine and Biomedical Sciences, University of Porto (ICBAS-UP), Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.
Publications dans "Hydralazine" :

Vânia Camilo

2 publications dans cette catégorie

Affiliations :
  • Cancer Biology and Epigenetics Group, Research Center of IPO Porto (CI-IPOP)/RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
Publications dans "Hydralazine" :

Rui Henrique

2 publications dans cette catégorie

Affiliations :
  • Cancer Biology and Epigenetics Group, Research Center of IPO Porto (CI-IPOP)/RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
  • Department of Pathology and Molecular Immunology, School of Medicine and Biomedical Sciences, University of Porto (ICBAS-UP), Rua de Jorge Viterbo Ferreira, 228, 4050-313 Porto, Portugal.
  • Department of Pathology, Portuguese Oncology Institute of Porto (IPO Porto), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
Publications dans "Hydralazine" :

Carmen Jerónimo

2 publications dans cette catégorie

Affiliations :
  • Cancer Biology and Epigenetics Group, Research Center of IPO Porto (CI-IPOP)/RISE@CI-IPOP (Health Research Network), Portuguese Oncology Institute of Porto (IPO Porto)/Porto Comprehensive Cancer Center (Porto.CCC), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
  • Department of Pathology, Portuguese Oncology Institute of Porto (IPO Porto), Rua Dr. António Bernardino de Almeida, 4200-072 Porto, Portugal.
Publications dans "Hydralazine" :

Xuguan Chen

2 publications dans cette catégorie

Affiliations :
  • Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China. Electronic address: chenxg@njmu.edu.cn.
Publications dans "Hydralazine" :

Yong Li

2 publications dans cette catégorie

Affiliations :
  • Department of Cardiology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, PR China. Electronic address: liyongmydream@126.com.
Publications dans "Hydralazine" :

Rachel D Crouch

2 publications dans cette catégorie

Affiliations :
  • Department of Pharmacy and Pharmaceutical Sciences, Lipscomb University College of Pharmacy, Nashville, Tennessee (J.P.B., S.M.Y., T.S.T., C.M.G., S.S.P., T.Q.D., R.D.C.); and Department of Pharmacology, Vanderbilt University School of Medicine, Nashville, Tennessee (R.D.C.) rachel.crouch@lipscomb.edu.
Publications dans "Hydralazine" :

Satoru Kudose

2 publications dans cette catégorie

Affiliations :
  • Department of Pathology, Columbia University Irving Medical Center, New York, New York, USA.
Publications dans "Hydralazine" :

Maryam Al-Hasani

2 publications dans cette catégorie

Affiliations :
  • Ultrasound Research Lab, Department of Radiology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Publications dans "Hydralazine" :

Theodore W Cary

2 publications dans cette catégorie

Affiliations :
  • Department of Radiology, Children's hospital of Philadelphia, Philadelphia, Pennsylvania, USA.
Publications dans "Hydralazine" :

Hamidreza Shetabi

2 publications dans cette catégorie

Affiliations :
  • Department of Anesthesiology, School of Medicine, Isfahan University of Medical Sciences Isfahan, Iran.
Publications dans "Hydralazine" :

David M Charytan

2 publications dans cette catégorie

Affiliations :
  • Nephrology Division, Department of Medicine, NYU Langone Medical Center, New York, New York, USA.
Publications dans "Hydralazine" :

Ting-Ting Chang

2 publications dans cette catégorie

Affiliations :
  • Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan, ROC.
Publications dans "Hydralazine" :

Jaw-Wen Chen

2 publications dans cette catégorie

Affiliations :
  • Institute of Pharmacology, National Yang-Ming University, Taipei, Taiwan, ROC; Cardiovascular Research Center, National Yang-Ming University, Taipei, Taiwan, ROC; Department of Medical Research, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; Department of Medicine, Taipei Veterans General Hospital, Taipei, Taiwan, ROC. Electronic address: jwchen@vghtpe.gov.tw.
Publications dans "Hydralazine" :

Benjamin P Larkin

2 publications dans cette catégorie

Affiliations :
  • Renal Research Laboratory, Royal North Shore Hospital, Kolling Institute of Medical Research, University of Sydney, Sydney, NSW, Australia.
Publications dans "Hydralazine" :

Sources (19 au total)

Treatment of acute-onset hypertension in pregnancy: A network meta-analysis of randomized controlled trials comparing anti-hypertensives and route of administration.

Dec 2023
DOI: 10.1016/j.preghy.2023.10.005 PMID: 37857042

Consensus on the relative efficacy of available antihypertensive agents used in pregnancy is lacking.... To compare treatment success with antihypertensives and categorize by route of administration.... MEDLINE, Embase, PubMed, Web of Science, Scopus, CINAHL, and clinicaltrials.gov were searched without date restriction.... Peer-reviewed randomized controlled trials (RCTs) comparing pharmacologic agents used to treat hypertension in parturients were included. Evaluated treatment groups included IV-labetalol (BBIV), IV-hy... Seventy-four studies (8324 patients) were eligible post PRISMA guidelines screening. Results were pooled using a Bayesian-approach for success of treatment (study defined target blood pressure), time ... Treatment success (primary outcome, 55 trials with 5518 patients) was analyzed. Surface under the cumulative ranking curve (SUCRA) was categorized for 13 drugs, CCBPO (0.84) followed by CCBSL (0.78) w... Oral calcium-channel blockers ranked highest for treatment success. Ketanserin achieved target blood pressure fastest, warranting additional research. The results should be interpreted with caution as...

Pregnancy Infant, Newborn Female Humans Antihypertensive Agents +9 autres

Hydralazine use can be associated with IgM-dominated immune complex-mediated glomerulonephritis.

29 Apr 2024
DOI: 10.1080/01913123.2024.2346660 PMID: 38685716

IgM-dominant immune complex-mediated glomerulonephritis (IgM-dominant ICMGN) is a rare renal entity, characterized by a membranoproliferative pattern by light microscopy, dominant IgM staining by immu... Seven IgM-dominant ICMGN cases were identified over 8 years. Their pathologic phenotypes and clinical scenarios were analyzed in detail.... Patients' ages ranged from 47 to 87 years old with 5 women and two men. Six of seven patients had drug-induced autoimmune phenomenon (hydralazine-induced positive ANCA and ANA). All of them had renal ... The hydralazine-induced autoimmune phenomenon can be seen in IgM-dominant ICMGN, which should be classified as a subtype of membranoproliferative glomerulonephritis....

Hydralazine combined with conventional therapy improved outcomes in severe systolic dysfunction and mitral regurgitation.

27 Oct 2023
DOI: 10.1002/ehf2.14564 PMID: 37897153

Patients with heart failure (HF) and reduced left ventricular ejection fraction (LVEF) accompanied by significant mitral regurgitation (MR) had poor outcome. Several vasodilator trials showed neutral ... The study was open-labelled, one-to-one ratio randomized designed. Consecutively hospitalized patients with decompensated HF symptoms, LVEF < 35%, and MR more than moderate severity were enrolled afte... When administered without inadequate preload, combining early up-titration of hydralazine with EBMs improves outcome in patients with severe systolic dysfunction and significant MR, and it is safe and...