Titre : Microbiologie

Microbiologie : Questions médicales fréquentes

Termes MeSH sélectionnés :

Platelet Function Tests
{ "@context": "https://schema.org", "@graph": [ { "@type": "MedicalWebPage", "name": "Microbiologie : Questions médicales les plus fréquentes", "headline": "Microbiologie : Comprendre les symptômes, diagnostics et traitements", "description": "Guide complet et accessible sur les Microbiologie : explications, diagnostics, traitements et prévention. Information médicale validée destinée aux patients.", "datePublished": "2024-02-14", "dateModified": "2025-05-09", "inLanguage": "fr", "medicalAudience": [ { "@type": "MedicalAudience", "name": "Grand public", "audienceType": "Patient", "healthCondition": { "@type": "MedicalCondition", "name": "Microbiologie" }, "suggestedMinAge": 18, "suggestedGender": "unisex" }, { "@type": "MedicalAudience", "name": "Médecins", "audienceType": "Physician", "geographicArea": { "@type": "AdministrativeArea", "name": "France" } }, { "@type": "MedicalAudience", "name": "Chercheurs", "audienceType": "Researcher", "geographicArea": { "@type": "AdministrativeArea", "name": "International" } } ], "reviewedBy": { "@type": "Person", "name": "Dr Olivier Menir", "jobTitle": "Expert en Médecine", "description": "Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale", "url": "/static/pages/docteur-olivier-menir.html", "alumniOf": { "@type": "EducationalOrganization", "name": "Université Paris Descartes" } }, "isPartOf": { "@type": "MedicalWebPage", "name": "Biologie", "url": "https://questionsmedicales.fr/mesh/D001695", "about": { "@type": "MedicalCondition", "name": "Biologie", "code": { "@type": "MedicalCode", "code": "D001695", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "H01.158.273" } } }, "hasPart": [ { "@type": "MedicalWebPage", "name": "Bactériologie", "alternateName": "Bacteriology", "url": "https://questionsmedicales.fr/mesh/D001432", "about": { "@type": "MedicalCondition", "name": "Bactériologie", "code": { "@type": "MedicalCode", "code": "D001432", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "H01.158.273.540.177" } } }, { "@type": "MedicalWebPage", "name": "Génétique microbienne", "alternateName": "Genetics, Microbial", "url": "https://questionsmedicales.fr/mesh/D005827", "about": { "@type": "MedicalCondition", "name": "Génétique microbienne", "code": { "@type": "MedicalCode", "code": "D005827", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "H01.158.273.540.367" } } }, { "@type": "MedicalWebPage", "name": "Mycologie", "alternateName": "Mycology", "url": "https://questionsmedicales.fr/mesh/D009172", "about": { "@type": "MedicalCondition", "name": "Mycologie", "code": { "@type": "MedicalCode", "code": "D009172", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "H01.158.273.540.553" } } }, { "@type": "MedicalWebPage", "name": "Pathologie végétale", "alternateName": "Plant Pathology", "url": "https://questionsmedicales.fr/mesh/D061066", "about": { "@type": "MedicalCondition", "name": "Pathologie végétale", "code": { "@type": "MedicalCode", "code": "D061066", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "H01.158.273.540.706" } } }, { "@type": "MedicalWebPage", "name": "Virologie", "alternateName": "Virology", "url": "https://questionsmedicales.fr/mesh/D014773", "about": { "@type": "MedicalCondition", "name": "Virologie", "code": { "@type": "MedicalCode", "code": "D014773", "codingSystem": "MeSH" }, "identifier": { "@type": "PropertyValue", "propertyID": "MeSH Tree", "value": "H01.158.273.540.859" } } } ], "about": { "@type": "MedicalCondition", "name": "Microbiologie", "alternateName": "Microbiology", "code": { "@type": "MedicalCode", "code": "D008829", "codingSystem": "MeSH" } }, "author": [ { "@type": "Person", "name": "None None", "url": "https://questionsmedicales.fr/author/None%20None", "affiliation": { "@type": "Organization", "name": "" } }, { "@type": "Person", "name": "Kyoung-Ho Song", "url": "https://questionsmedicales.fr/author/Kyoung-Ho%20Song", "affiliation": { "@type": "Organization", "name": "Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea." } }, { "@type": "Person", "name": "Eu Suk Kim", "url": "https://questionsmedicales.fr/author/Eu%20Suk%20Kim", "affiliation": { "@type": "Organization", "name": "Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea." } }, { "@type": "Person", "name": "Yee Gyung Kwak", "url": "https://questionsmedicales.fr/author/Yee%20Gyung%20Kwak", "affiliation": { "@type": "Organization", "name": "Department of Internal Medicine, Inje University Ilsan Paik Hospital, Goyang, Republic of Korea." } }, { "@type": "Person", "name": "Hong Bin Kim", "url": "https://questionsmedicales.fr/author/Hong%20Bin%20Kim", "affiliation": { "@type": "Organization", "name": "Department of Internal Medicine, Seoul National University Bundang Hospital, Seongnam, Republic of Korea." } } ], "citation": [ { "@type": "ScholarlyArticle", "name": "Flow Cytometry and Platelets.", "datePublished": "2024-06-04", "url": "https://questionsmedicales.fr/article/39089755", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.cll.2024.04.011" } }, { "@type": "ScholarlyArticle", "name": "On-treatment platelet reactivity through the thromboxane A", "datePublished": "2023-06-20", "url": "https://questionsmedicales.fr/article/37338713", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1007/s11239-023-02818-6" } }, { "@type": "ScholarlyArticle", "name": "Multicenter evaluation of light transmission platelet aggregation reagents: communication from the ISTH SSC Subcommittee on Platelet Physiology.", "datePublished": "2023-06-16", "url": "https://questionsmedicales.fr/article/37331519", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1016/j.jtha.2023.05.027" } }, { "@type": "ScholarlyArticle", "name": "Advances in Platelet-Dysfunction Diagnostic Technologies.", "datePublished": "2024-06-17", "url": "https://questionsmedicales.fr/article/38927117", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.3390/biom14060714" } }, { "@type": "ScholarlyArticle", "name": "Postinjury platelet aggregation and venous thromboembolism.", "datePublished": "2022-05-21", "url": "https://questionsmedicales.fr/article/35444156", "identifier": { "@type": "PropertyValue", "propertyID": "DOI", "value": "10.1097/TA.0000000000003655" } } ], "breadcrumb": { "@type": "BreadcrumbList", "itemListElement": [ { "@type": "ListItem", "position": 1, "name": "questionsmedicales.fr", "item": "https://questionsmedicales.fr" }, { "@type": "ListItem", "position": 2, "name": "Disciplines des sciences naturelles", "item": "https://questionsmedicales.fr/mesh/D010811" }, { "@type": "ListItem", "position": 3, "name": "Disciplines des sciences biologiques", "item": "https://questionsmedicales.fr/mesh/D001690" }, { "@type": "ListItem", "position": 4, "name": "Biologie", "item": "https://questionsmedicales.fr/mesh/D001695" }, { "@type": "ListItem", "position": 5, "name": "Microbiologie", "item": "https://questionsmedicales.fr/mesh/D008829" } ] } }, { "@type": "MedicalWebPage", "name": "Article complet : Microbiologie - Questions et réponses", "headline": "Questions et réponses médicales fréquentes sur Microbiologie", "description": "Une compilation de questions et réponses structurées, validées par des experts médicaux.", "datePublished": "2025-05-16", "inLanguage": "fr", "hasPart": [ { "@type": "MedicalWebPage", "name": "Diagnostic", "headline": "Diagnostic sur Microbiologie", "description": "Comment diagnostiquer une infection bactérienne ?\nQuels tests pour identifier un virus ?\nComment détecter des champignons dans le corps ?\nQuels examens pour les infections parasitaires ?\nQuel rôle joue la microscopie en microbiologie ?", "url": "https://questionsmedicales.fr/mesh/D008829?mesh_terms=Platelet+Function+Tests&page=3#section-diagnostic" }, { "@type": "MedicalWebPage", "name": "Symptômes", "headline": "Symptômes sur Microbiologie", "description": "Quels sont les symptômes d'une infection bactérienne ?\nComment reconnaître une infection virale ?\nQuels signes d'infection fongique ?\nQuels symptômes d'une infection parasitaire ?\nComment les infections affectent-elles le système immunitaire ?", "url": "https://questionsmedicales.fr/mesh/D008829?mesh_terms=Platelet+Function+Tests&page=3#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Microbiologie", "description": "Comment prévenir les infections bactériennes ?\nQuelles mesures pour éviter les infections virales ?\nComment prévenir les infections fongiques ?\nQuelles précautions contre les infections parasitaires ?\nQuel rôle de l'éducation en santé ?", "url": "https://questionsmedicales.fr/mesh/D008829?mesh_terms=Platelet+Function+Tests&page=3#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Microbiologie", "description": "Quels antibiotiques pour les infections bactériennes ?\nComment traiter une infection virale ?\nQuels antifongiques pour les infections fongiques ?\nComment traiter une infection parasitaire ?\nQuel rôle des probiotiques dans le traitement ?", "url": "https://questionsmedicales.fr/mesh/D008829?mesh_terms=Platelet+Function+Tests&page=3#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Microbiologie", "description": "Quelles complications des infections bactériennes ?\nQuels risques d'infections virales ?\nQuelles complications des infections fongiques ?\nQuels effets des infections parasitaires ?\nComment les infections affectent-elles la santé à long terme ?", "url": "https://questionsmedicales.fr/mesh/D008829?mesh_terms=Platelet+Function+Tests&page=3#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Microbiologie", "description": "Quels facteurs de risque pour les infections bactériennes ?\nComment le mode de vie influence-t-il les infections virales ?\nQuels facteurs de risque pour les infections fongiques ?\nComment l'environnement affecte-t-il les infections parasitaires ?\nQuel impact de la résistance aux antibiotiques ?", "url": "https://questionsmedicales.fr/mesh/D008829?mesh_terms=Platelet+Function+Tests&page=3#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment diagnostiquer une infection bactérienne ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "Un diagnostic se fait par culture bactérienne et tests de sensibilité." } }, { "@type": "Question", "name": "Quels tests pour identifier un virus ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Les tests PCR et les sérologies sont utilisés pour identifier les virus." } }, { "@type": "Question", "name": "Comment détecter des champignons dans le corps ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "On utilise des cultures fongiques et des examens microscopiques." } }, { "@type": "Question", "name": "Quels examens pour les infections parasitaires ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Les examens de selles et les tests sérologiques sont courants." } }, { "@type": "Question", "name": "Quel rôle joue la microscopie en microbiologie ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "La microscopie permet d'observer les micro-organismes et leur morphologie." } }, { "@type": "Question", "name": "Quels sont les symptômes d'une infection bactérienne ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Fièvre, douleur, rougeur et gonflement sont des symptômes fréquents." } }, { "@type": "Question", "name": "Comment reconnaître une infection virale ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Symptômes comme fièvre, fatigue, toux et douleurs musculaires sont typiques." } }, { "@type": "Question", "name": "Quels signes d'infection fongique ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "Les démangeaisons, rougeurs et éruptions cutanées peuvent indiquer une infection fongique." } }, { "@type": "Question", "name": "Quels symptômes d'une infection parasitaire ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Les douleurs abdominales, diarrhée et fatigue sont souvent observées." } }, { "@type": "Question", "name": "Comment les infections affectent-elles le système immunitaire ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Les infections peuvent affaiblir le système immunitaire, rendant l'organisme vulnérable." } }, { "@type": "Question", "name": "Comment prévenir les infections bactériennes ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "Le lavage des mains et la vaccination sont des mesures préventives clés." } }, { "@type": "Question", "name": "Quelles mesures pour éviter les infections virales ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Éviter le contact étroit et se faire vacciner sont essentiels." } }, { "@type": "Question", "name": "Comment prévenir les infections fongiques ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Maintenir une bonne hygiène et éviter l'humidité aide à prévenir ces infections." } }, { "@type": "Question", "name": "Quelles précautions contre les infections parasitaires ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Éviter l'eau contaminée et bien cuire les aliments sont des précautions importantes." } }, { "@type": "Question", "name": "Quel rôle de l'éducation en santé ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "L'éducation en santé sensibilise aux pratiques préventives et réduit les infections." } }, { "@type": "Question", "name": "Quels antibiotiques pour les infections bactériennes ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les antibiotiques comme la pénicilline et la céphalexine sont couramment utilisés." } }, { "@type": "Question", "name": "Comment traiter une infection virale ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Les antiviraux et les soins symptomatiques sont souvent recommandés." } }, { "@type": "Question", "name": "Quels antifongiques pour les infections fongiques ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Les antifongiques comme le fluconazole et l'amphotéricine B sont utilisés." } }, { "@type": "Question", "name": "Comment traiter une infection parasitaire ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "Les antiparasitaires comme la mébendazole sont prescrits selon le parasite." } }, { "@type": "Question", "name": "Quel rôle des probiotiques dans le traitement ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Les probiotiques aident à restaurer la flore intestinale après une antibiothérapie." } }, { "@type": "Question", "name": "Quelles complications des infections bactériennes ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Les complications incluent septicémie, choc et défaillance d'organes." } }, { "@type": "Question", "name": "Quels risques d'infections virales ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Les infections virales peuvent entraîner des pneumonies et des encéphalites." } }, { "@type": "Question", "name": "Quelles complications des infections fongiques ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Les infections fongiques peuvent causer des infections systémiques graves." } }, { "@type": "Question", "name": "Quels effets des infections parasitaires ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Les infections parasitaires peuvent entraîner des anémies et des troubles digestifs." } }, { "@type": "Question", "name": "Comment les infections affectent-elles la santé à long terme ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Certaines infections peuvent causer des séquelles chroniques et des maladies auto-immunes." } }, { "@type": "Question", "name": "Quels facteurs de risque pour les infections bactériennes ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "L'âge, le diabète et l'immunodépression augmentent le risque d'infections." } }, { "@type": "Question", "name": "Comment le mode de vie influence-t-il les infections virales ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Un mode de vie sédentaire et le stress peuvent accroître la vulnérabilité." } }, { "@type": "Question", "name": "Quels facteurs de risque pour les infections fongiques ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "L'immunodépression et l'humidité excessive favorisent les infections fongiques." } }, { "@type": "Question", "name": "Comment l'environnement affecte-t-il les infections parasitaires ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Les conditions sanitaires précaires et l'eau contaminée augmentent le risque." } }, { "@type": "Question", "name": "Quel impact de la résistance aux antibiotiques ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "La résistance aux antibiotiques augmente le risque d'infections graves et difficiles à traiter." } } ] } ] }

Sources (10000 au total)

On-treatment platelet reactivity through the thromboxane A

Pelacarsen decreases plasma levels of lipoprotein(a) [Lp(a)] and oxidized phospholipids (OxPL). It was previously reported that pelacarsen does not affect the platelet count. We now report the effect ... Subjects with established cardiovascular disease and screening Lp(a) levels ≥60 mg per deciliter (~ ≥150 nmol/L) were randomized to receive pelacarsen (20, 40, or 60 mg every 4 weeks; 20 mg every 2 we... Of the 286 subjects randomized, 275 had either an ARU or PRU test, 159 (57.8%) were on aspirin alone and 94 (34.2%) subjects were on dual anti-platelet therapy. As expected, the baseline ARU and PRU w... Pelacarsen does not modify on-treatment platelet reactivity through the thromboxane A...

Multicenter evaluation of light transmission platelet aggregation reagents: communication from the ISTH SSC Subcommittee on Platelet Physiology.

Light transmission aggregation (LTA) is used widely by the clinical and research communities. Although it is a gold standard, there is a lack of interlaboratory harmonization.... The primary objective was to assess whether sources of activators (mainly adenosine diphosphate [ADP], collagen, arachidonic acid, epinephrine, and thrombin receptor activating peptide6) and ristoceti... An international multicenter study involving 28 laboratories in which we compared LTA results obtained with center-specific activators and a comparator that we supplied.... We report variability in the potency (P) of activators in comparison with the comparator. Thrombin receptor activating peptide 6 (P, 1.32-2.68), arachidonic acid (P, 0.87-1.43), and epinephrine (P, 0.... Based on these data, the establishment and adoption of simple standardization principles should mitigate variability due to activator sources. The observation of huge interindividual variability for c...

Postinjury platelet aggregation and venous thromboembolism.

Posttraumatic venous thromboembolism (VTE) remains prevalent in severely injured patients despite chemoprophylaxis. Importantly, although platelets are central to thrombosis, they are not routinely ta... We performed a secondary analysis of 133 severely injured patients from a prospective observational study investigating coagulation and inflammation (2011-2019). Platelet aggregation in response to st... The 133 patients were severely injured (median Injury Severity Score, 25), and 14% developed VTE (all >48 hours after admission). At presentation, platelet count and PA were not significantly differen... Severely injured patients with decreasing ex vivo measures of PA despite resuscitation have an increased risk of developing VTE. This may have implications for predicting development of VTE and for st... Prognostic/Epidemiological; Level III....

Gamma and X-ray irradiation do not affect the in vitro quality of refrigerated apheresis platelets in platelet additive solution (PAS-E).

Platelet refrigeration (cold storage) provides the advantages of an extended shelf life and reduces the risk of bacterial growth, compared to platelets stored at room temperature (RT). However, proces... Triple-dose apheresis platelets were collected in 40% plasma/60% PAS-E, using the TRIMA apheresis platform, and refrigerated (2-6°C) within 8 h of collection. On day 2, one of each component was gamma... The platelet concentration decreased by approximately 20% in all groups during 21 days of storage (p > .05). Irradiation (gamma or X-ray) did not affect platelet metabolism, and the pH was maintained ... Gamma and X-ray irradiation do not affect the in vitro quality of platelet components stored in the cold for up to 21 days. This demonstrates the acceptability of irradiating cold-stored platelets, wh...

In vitro quality of cold and delayed cold-stored platelet concentrates from interim platelet units during storage for 21 days.

Based on previous success using apheresis platelets, we wanted to investigate the in vitro quality and platelet function in continuously cold-stored and delayed cold-stored platelet concentrates (PCs)... We used a pool-and-split design to prepare 18 identical pairs of PCs. One unit was stored unagitated and refrigerated after production on day 1 (cold-stored). The other unit was stored agitated at roo... All PCs complied with European recommendations (EDQM 20th edition). Both groups had mean platelet content >200 × 10... Our findings suggest that PCs from IPUs are suitable for cold storage from day 1 until day 21 and delayed cold storage from day 5 until day 14....

Hyperbaric treatment of platelets extends in vitro storage to 14 days.

Platelets for transfusion have a storage time of 5-7 days at 22°C-24°C, which results in a strain on the supply chain and supply shortages. We describe a novel method to extend platelet storage using ... Apheresis platelets (APU) prepared in 65% platelet additive solution (PAS) were stored under standard conditions (SC) at 20°C-24°C to Day 5. Paired APUs were prepared with Xe and stored to Day 14 at 2... XHC platelets were viable out to Day 14. The average pH of Day 14 platelets was 6.58, and 86% maintained some degree of swirl compared with 7.02 and 100% swirl for Day 5 SC platelets. The rate of glyc... Platelet storage with the Xe/hyperbaric/cold method is a feasible candidate for extension of storage to 14 days based on in vitro characteristics. In vivo recovery and survival studies are indicated. ...

Cell Surface Platelet Tissue Factor Expression: Regulation by P2Y

ADP-induced platelet activation leads to cell surface expression of several proteins, including TF (tissue factor). The role of ADP receptors in platelet TF modulation is still unknown. We aimed to as... The effects of P2Y... In blood from healthy subjects, stimulated in vitro by ADP, the percentage of TF... Data show that TF expression is regulated by P2Y...