questionsmedicales.fr
Phénomènes génétiques
Variation génétique
Mutation
Aberrations des chromosomes
Mosaïcisme
Mosaïcisme : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Mosaïcisme
Analyse génétique
Cytogénétique
Séquençage de l'ADN
Amniocentèse
Biopsie de villosités choriales
Anomalies congénitales
Troubles du développement
Génétique
Mutation somatique
Symptômes
5
Symptômes
Malformations congénitales
Retard de développement
Troubles cognitifs
Anomalies cutanées
Pigmentation
Malformations cardiaques
Mosaïcisme
Variabilité phénotypique
Distribution cellulaire
Prévention
5
Prévention
Mutation somatique
Conseils génétiques
Risques
Tests génétiques
Mosaïcisme
Éducation prénatale
Options
Habitudes de vie
Génétique
Traitements
5
Traitement
Intervention chirurgicale
Suivi médical
Complications
Thérapie ciblée
Symptômes
Qualité de vie
Soins palliatifs
Complications
5
Complications
Malformations
Complications neurologiques
Cellules affectées
Gestion des complications
Suivi régulier
Facteurs de risque
5
Facteurs de risque
Anomalies chromosomiques
Âge parental
Mutations génétiques
Facteurs environnementaux
Mutations somatiques
Antécédents familiaux
Maladies génétiques
Infections virales
Mutations
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"@type": "Question",
"name": "Comment diagnostiquer le mosaïcisme ?",
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"text": "Le diagnostic se fait par analyse génétique et biopsies tissulaires."
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"@type": "Question",
"name": "Quels tests sont utilisés pour le mosaïcisme ?",
"position": 2,
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"@type": "Question",
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"@type": "Question",
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"@type": "Question",
"name": "Le mosaïcisme peut-il affecter le développement intellectuel ?",
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"@type": "Question",
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"position": 8,
"acceptedAnswer": {
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"text": "Oui, des anomalies cutanées comme des taches pigmentées peuvent apparaître."
}
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{
"@type": "Question",
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"acceptedAnswer": {
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{
"@type": "Question",
"name": "Les symptômes varient-ils d'une personne à l'autre ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'expression des symptômes dépend des cellules affectées et de leur distribution."
}
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{
"@type": "Question",
"name": "Peut-on prévenir le mosaïcisme ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le mosaïcisme ne peut pas être prévenu car il résulte de mutations somatiques."
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{
"@type": "Question",
"name": "Y a-t-il des conseils pour les parents ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les parents peuvent bénéficier de conseils génétiques pour comprendre les risques."
}
},
{
"@type": "Question",
"name": "Les tests génétiques peuvent-ils aider ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les tests génétiques peuvent identifier des risques de mosaïcisme chez les enfants."
}
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{
"@type": "Question",
"name": "L'éducation prénatale est-elle utile ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'éducation prénatale aide à comprendre les risques et les options disponibles."
}
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"@type": "Question",
"name": "Les habitudes de vie influencent-elles le mosaïcisme ?",
"position": 15,
"acceptedAnswer": {
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"@type": "Question",
"name": "Quel traitement est disponible pour le mosaïcisme ?",
"position": 16,
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"text": "Le traitement dépend des symptômes et peut inclure des interventions chirurgicales."
}
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{
"@type": "Question",
"name": "Le mosaïcisme nécessite-t-il un suivi médical ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, un suivi régulier est essentiel pour gérer les complications potentielles."
}
},
{
"@type": "Question",
"name": "Des thérapies spécifiques existent-elles ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies ciblées peuvent être envisagées selon les symptômes et les tissus affectés."
}
},
{
"@type": "Question",
"name": "Le traitement est-il curatif ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Il n'existe pas de traitement curatif, mais des soins peuvent améliorer la qualité de vie."
}
},
{
"@type": "Question",
"name": "Les médicaments sont-ils utilisés pour le mosaïcisme ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des médicaments peuvent être prescrits pour traiter des symptômes spécifiques."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les complications incluent des malformations, des troubles de la croissance et des cancers."
}
},
{
"@type": "Question",
"name": "Le mosaïcisme augmente-t-il le risque de cancer ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains types de mosaïcisme peuvent être associés à un risque accru de cancer."
}
},
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"@type": "Question",
"name": "Des complications neurologiques sont-elles possibles ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des complications neurologiques peuvent survenir selon les cellules affectées."
}
},
{
"@type": "Question",
"name": "Le mosaïcisme peut-il affecter la fertilité ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines formes de mosaïcisme peuvent avoir un impact sur la fertilité."
}
},
{
"@type": "Question",
"name": "Comment gérer les complications ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "La gestion des complications nécessite une approche multidisciplinaire et un suivi régulier."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque du mosaïcisme ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent des anomalies chromosomiques et des mutations génétiques."
}
},
{
"@type": "Question",
"name": "L'âge parental influence-t-il le mosaïcisme ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'âge avancé des parents peut augmenter le risque de mutations génétiques."
}
},
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"@type": "Question",
"name": "Des facteurs environnementaux jouent-ils un rôle ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines expositions environnementales peuvent contribuer à des mutations somatiques."
}
},
{
"@type": "Question",
"name": "Les antécédents familiaux sont-ils un facteur ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les antécédents familiaux de maladies génétiques peuvent augmenter le risque."
}
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"@type": "Question",
"name": "Le mosaïcisme est-il lié à des infections ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines infections virales peuvent être associées à des mutations, mais ce n'est pas direct."
}
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 03/04/2025
Contenu vérifié selon les dernières recommandations médicales
2 publications dans cette catégorie
Affiliations :
Department of Dermatology, Yale School of Medicine, New Haven, Connecticut, USA; Department of Pathology, Yale School of Medicine, New Haven, Connecticut, USA; Department of Genetics, Yale School of Medicine, New Haven, Connecticut, USA. Electronic address: keith.choate@yale.edu.
Publications dans "Mosaïcisme" :
2 publications dans cette catégorie
Affiliations :
From the Department of Neurosurgery (H.W.P.), Stanford School of Medicine, Palo Alto, CA; Department of Neurosurgery (H.W.P., J.R.M., J.P., S.S.S.), Boston Children's Hospital, Harvard Medical School; Broad Institute of MIT and Harvard (H.W.P., Y.W., Y.C., E.A.L., A.Y.H., C.A.W.), Cambridge; Division of Genetics and Genomics (H.W.P., Y.W., E.A.L., A.Y.H., C.A.W.), Manton Center for Orphan Disease Research; Division of Newborn Medicine (A.M.D.G., B.A.), Department of Pediatrics; Epilepsy Genetics Program (A.M.D.G., J.B.B., A.P.), Department of Neurology; Department of Pediatrics (A.M.D.G., J.B.B., E.A.L., A.Y.H., C.A.W.), Harvard Medical School, Boston Children's Hospital; Program in Biological and Biomedical Sciences (Y.W.); Department of Neurology (M.C., J.B.B., A.P., C.A.W.), Boston Children's Hospital, Harvard Medical School; Translational Neuroscience Center (A.C.S.), Boston Children's Hospital; Department of Radiology (S.P.P.), Division of Neuroradiology; Department of Pathology (H.G.L.), Division of Neuropathology, Boston Children's Hospital, Harvard Medical School; and Howard Hughes Medical Institute (C.A.W.), Boston, MA.
Publications dans "Mosaïcisme" :
2 publications dans cette catégorie
Affiliations :
ICAR-Central Institute of Temperate Horticulture, Srinagar 191132, Jammu & Kashmir, India.
Publications dans "Mosaïcisme" :
2 publications dans cette catégorie
Affiliations :
ICAR-Central Institute of Temperate Horticulture, Srinagar 191132, Jammu & Kashmir, India.
Publications dans "Mosaïcisme" :
2 publications dans cette catégorie
Affiliations :
ICAR-Central Institute of Temperate Horticulture, Srinagar 191132, Jammu & Kashmir, India.
Publications dans "Mosaïcisme" :
2 publications dans cette catégorie
Affiliations :
Epilepsy Research Centre, Department of Medicine (Austin Hospital), University of Melbourne, Heidelberg, Victoria, Australia 3084.
Publications dans "Mosaïcisme" :
2 publications dans cette catégorie
Affiliations :
Epilepsy Research Centre, Department of Medicine (Austin Hospital), University of Melbourne, Heidelberg, Victoria, Australia 3084.
Murdoch Children's Research Institute, Parkville, Victoria, Australia 3052.
Publications dans "Mosaïcisme" :
2 publications dans cette catégorie
Affiliations :
IST Austria (Institute of Science and Technology Austria), Am Campus 1, 3400 Klosterneuburg, Austria.
Publications dans "Mosaïcisme" :
2 publications dans cette catégorie
Affiliations :
IST Austria (Institute of Science and Technology Austria), Am Campus 1, 3400 Klosterneuburg, Austria.
Publications dans "Mosaïcisme" :
2 publications dans cette catégorie
Affiliations :
Deparment of Applied Genomics, Kazusa DNA Research Institute, Kisarazu, Japan.
Publications dans "Mosaïcisme" :
1 publication dans cette catégorie
Affiliations :
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Publications dans "Mosaïcisme" :
1 publication dans cette catégorie
Affiliations :
Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA.
Publications dans "Mosaïcisme" :
1 publication dans cette catégorie
Affiliations :
Department of Nephrology, The Children's Hospital, Zhejiang University School of Medicine and National Clinical Research Center for Child Health, Hangzhou, China.
Publications dans "Mosaïcisme" :
1 publication dans cette catégorie
Affiliations :
Institute of Genetics and Department of Human Genetics, Zhejiang University School of Medicine, Hangzhou, China.
Publications dans "Mosaïcisme" :
1 publication dans cette catégorie
Affiliations :
Department of Nephrology, The Children's Hospital, Zhejiang University School of Medicine and National Clinical Research Center for Child Health, Hangzhou, China.
Publications dans "Mosaïcisme" :
1 publication dans cette catégorie
Affiliations :
Department of Nephrology, The Children's Hospital, Zhejiang University School of Medicine and National Clinical Research Center for Child Health, Hangzhou, China.
Publications dans "Mosaïcisme" :
1 publication dans cette catégorie
Affiliations :
Department of Nephrology, The Children's Hospital, Zhejiang University School of Medicine and National Clinical Research Center for Child Health, Hangzhou, China.
Publications dans "Mosaïcisme" :
1 publication dans cette catégorie
Affiliations :
Institute of Genetics and Department of Human Genetics, Zhejiang University School of Medicine, Hangzhou, China.
Publications dans "Mosaïcisme" :
1 publication dans cette catégorie
Affiliations :
Department of Nephrology, The Children's Hospital, Zhejiang University School of Medicine and National Clinical Research Center for Child Health, Hangzhou, China.
Publications dans "Mosaïcisme" :
1 publication dans cette catégorie
Affiliations :
Department of Nephrology, The Children's Hospital, Zhejiang University School of Medicine and National Clinical Research Center for Child Health, Hangzhou, China.
Publications dans "Mosaïcisme" :
Treatments that alleviate insomnia over the long term are critical. We evaluated the relative long-term efficacy of cognitive therapy (CT), behavior therapy (BT), and cognitive behavior therapy (CBT) ...
Patients (...
Patients in all three treatment groups improved on insomnia severity, sleep onset latency, wake after sleep onset, total sleep time, sleep efficiency, work and social adjustment, and mental health (...
These encouraging results suggest that therapists may be able to offer CBT, BT, or CT to improve nighttime and daytime symptoms of insomnia over the long-term, with CBT offering a relative advantage f...
The first randomized clinical trial of dialectical behavior therapy (DBT) for women with borderline personality disorder was published in 1991. Over the past 30 years, research on DBT has proliferated...
Transdiagnostic treatments have been designed to target common processes for clusters of disorders. One such treatment, transdiagnostic behavior therapy (TBT), targets avoidance across emotional disor...
The fields of couple therapy and sex therapy have historically been divided, with sex therapists focusing on sexual problems as fuel for relationship distress and couple therapists conceptualizing rel...
This article provides an overview of the application of CBT in the management of episodic migraine while also providing context and insight into the underlying neurophysiological mechanisms of therape...
Cognitive behavioral therapy (CBT) is an empirically based treatment that is well suited for the management of episodic migraine. Although first-line treatments of migraine are typically pharmacologic...
To evaluate whether the results of a quasi-randomized study, comparing dialectical behavior therapy for binge-eating disorder (DBT-BED) and an intensive, outpatient cognitive behavior therapy (CBT+) i...
Patients with (subthreshold) BED (N = 175) started one of two group treatments: DBT-BED (n = 42) or CBT+ (n = 133), at a community eating disorder service. Measures of eating disorder pathology, emoti...
Both treatments lead to substantial decreases on primary and secondary measures. Statistically significant, medium-size differences between groups were limited to global eating disorder psychopatholog...
Decreases in global eating disorder psychopathology were achieved faster with CBT+. Overall, improvements in DBT-BED were comparable to those observed in CBT+. Findings of the original trial, favoring...
In this effectiveness study, dialectical behavior therapy (DBT) resulted in clinically relevant improvements in individuals with binge eating disorder. Changes were broadly comparable to those of cogn...
Dysregulated anger, and its common behavioral urge, aggression, pose substantial costs to public health and society. Though some studies have shown DBT to be efficacious in treating aggression and ang...
With growing evidence to support their efficacy, brain-gut behavior therapies are increasingly viewed as a key component to integrated care management of disorders of gut-brain interaction. However, t...
Psychotherapy is a learning process. Updating the prediction models of the brain may be the mechanism underlying psychotherapeutic changes. Although developed in different eras and cultures, dialectic...
To examine if the processes in the cognitive model mediate cognitive therapy (CT) and behavior therapy (BT) for insomnia....
Individuals diagnosed with insomnia disorder (...
Parallel process growth modeling showed that dysfunctional beliefs, monitoring, and safety behaviors significantly mediated the effects of both CT and BT. Cross-lagged panel models confirmed that dysf...
Together, the findings support the role of dysfunctional beliefs and monitoring as processes of change in CT and safety behaviors as a specific mediator in BT. Limited evidence was provided for worry ...