Controlling differentiation of stem cells
Ideal bone tissue engineering is to induce bone regeneration through the synergistic integration of biomaterial scaffolds, bone progenitor cells, and bone-forming factors. Biomimetic scaffolds imitate...
Activité de type insulinique non suppressible : Questions médicales fréquentes
Questions fréquentes et termes MeSH associés
Diagnostic 5
#1
Comment diagnostiquer l'activité insulinique non suppressible ?
Des tests sanguins mesurant les niveaux d'insuline et de glucose sont effectués.
#2
Quels tests sont utilisés pour évaluer cette condition ?
Le test de tolérance au glucose et les dosages d'insuline sont courants.
#3
Quels signes cliniques indiquent cette activité ?
Des symptômes comme l'hyperglycémie persistante peuvent être observés.
#4
L'imagerie est-elle utile pour le diagnostic ?
L'imagerie n'est généralement pas utilisée pour cette condition spécifique.
#5
Peut-on utiliser des biomarqueurs pour le diagnostic ?
Oui, des biomarqueurs comme le peptide C peuvent aider à évaluer l'insulinémie.
Symptômes 5
#1
Quels sont les symptômes courants de cette condition ?
Les symptômes incluent fatigue, soif excessive et besoin fréquent d'uriner.
#2
L'hypoglycémie est-elle un symptôme possible ?
Oui, des épisodes d'hypoglycémie peuvent survenir malgré une insulinémie élevée.
#3
Y a-t-il des symptômes liés à la prise de poids ?
Oui, une prise de poids inexpliquée peut être un symptôme associé.
#4
Les troubles de la vision sont-ils possibles ?
Oui, des troubles visuels peuvent survenir en raison de l'hyperglycémie prolongée.
#5
Des symptômes cutanés peuvent-ils apparaître ?
Oui, des infections cutanées fréquentes peuvent être un signe d'insulinorésistance.
Prévention 5
#1
Comment prévenir l'activité insulinique non suppressible ?
Maintenir un poids santé et adopter un mode de vie actif sont essentiels.
#2
L'alimentation joue-t-elle un rôle préventif ?
Oui, une alimentation équilibrée peut réduire le risque de résistance à l'insuline.
#3
Le dépistage précoce est-il important ?
Oui, le dépistage régulier peut aider à identifier les problèmes tôt.
#4
Le stress influence-t-il cette condition ?
Oui, le stress peut aggraver la résistance à l'insuline et les symptômes.
#5
Les habitudes de sommeil affectent-elles la prévention ?
Oui, un sommeil de qualité est crucial pour la régulation de l'insuline.
Traitements 5
#1
Quels traitements sont disponibles pour cette condition ?
Les traitements incluent des médicaments antidiabétiques et des modifications du mode de vie.
#2
L'insuline est-elle utilisée dans le traitement ?
Oui, l'insuline peut être administrée pour contrôler les niveaux de glucose.
#3
Les changements alimentaires sont-ils recommandés ?
Oui, un régime équilibré et pauvre en glucides est souvent conseillé.
#4
La thérapie physique peut-elle aider ?
Oui, l'exercice régulier peut améliorer la sensibilité à l'insuline.
#5
Des traitements alternatifs existent-ils ?
Certaines approches comme la médecine complémentaire peuvent être explorées.
Complications 5
#1
Quelles complications peuvent survenir ?
Des complications comme le diabète de type 2 et des maladies cardiovasculaires peuvent se développer.
#2
L'insulinorésistance peut-elle entraîner des complications ?
Oui, l'insulinorésistance est liée à des complications métaboliques graves.
#3
Des problèmes rénaux peuvent-ils se développer ?
Oui, des maladies rénales chroniques peuvent être une complication de cette condition.
#4
Les troubles neurologiques sont-ils possibles ?
Oui, des neuropathies peuvent survenir en raison de l'hyperglycémie prolongée.
#5
Y a-t-il un risque accru de maladies cardiaques ?
Oui, le risque de maladies cardiaques est significativement augmenté.
Facteurs de risque 5
#1
Quels sont les principaux facteurs de risque ?
L'obésité, le manque d'exercice et des antécédents familiaux sont des facteurs clés.
#2
L'âge influence-t-il le risque ?
Oui, le risque augmente avec l'âge, surtout après 45 ans.
#3
Le tabagisme est-il un facteur de risque ?
Oui, le tabagisme est associé à une augmentation de la résistance à l'insuline.
#4
Les antécédents médicaux jouent-ils un rôle ?
Oui, des antécédents de diabète gestationnel augmentent le risque futur.
#5
Le stress chronique est-il un facteur de risque ?
Oui, le stress chronique peut contribuer à l'insulinorésistance.
Contenu validé par Dr Olivier Menir
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 31/03/2025
Contenu vérifié selon les dernières recommandations médicales
Auteurs principaux
Jie Li
4 publications dans cette catégorie
Affiliations :
- Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nature communications 2019-10-08
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Xiao-Chen Bai
4 publications dans cette catégorie
Affiliations :
- Department of Biophysics, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. Xiaochen.Bai@UTSouthwestern.edu.
- Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, TX, 75390, USA. Xiaochen.Bai@UTSouthwestern.edu.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nature communications 2019-10-08
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Eunhee Choi
4 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA. EC3477@cumc.columbia.edu.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Structural basis of the activation of type 1 insulin-like growth factor receptor.
Nature communications 2019-10-08
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Catherine Hall
3 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Jiayi Wu
3 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Molecular basis for the role of disulfide-linked αCTs in the activation of insulin-like growth factor 1 receptor and insulin receptor.
eLife 2022-11-22
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Junhee Park
2 publications dans cette catégorie
Affiliations :
- Department of Pathology and Cell Biology, Vagelos College of Physicians and Surgeons, Columbia University, New York, NY, 10032, USA.
Publications dans "Activité de type insulinique non suppressible" :
-
Activation of the insulin receptor by insulin-like growth factor 2.
Nature communications 2024-03-23
-
Activation of the insulin receptor by an insulin mimetic peptide.
Nature communications 2022-09-23
Christopher T V Swain
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Ann E Drummond
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Roger L Milne
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
- Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Dallas R English
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Kristy A Brown
2 publications dans cette catégorie
Affiliations :
- Department of Medicine, Weill Cornell Medicine, New York, New York.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Tina L Skinner
2 publications dans cette catégorie
Affiliations :
- The University of Queensland, School of Human Movement and Nutrition Sciences, St. Lucia, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Eline H van Roekel
2 publications dans cette catégorie
Affiliations :
- Department of Epidemiology, GROW School for Oncology and Developmental Biology, Maastricht University, Maastricht, the Netherlands.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Melissa M Moore
2 publications dans cette catégorie
Affiliations :
- Medical Oncology, St. Vincent's Hospital, Melbourne, Australia.
- Department of Medicine, The University of Melbourne, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Tom R Gaunt
2 publications dans cette catégorie
Affiliations :
- Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Richard M Martin
2 publications dans cette catégorie
Affiliations :
- Bristol Medical School, University of Bristol, Bristol, United Kingdom.
- IHR Biomedical Research Centre at University Hospitals Bristol and Weston NHS Foundation Trust and the University of Bristol, Bristol, United Kingdom.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Sarah J Lewis
2 publications dans cette catégorie
Affiliations :
- Bristol Medical School, University of Bristol, Bristol, United Kingdom.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Brigid M Lynch
2 publications dans cette catégorie
Affiliations :
- Cancer Epidemiology Division, Cancer Council Victoria, Melbourne, Australia.
- Centre for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Melbourne, Australia.
- Physical Activity Laboratory, Baker Heart and Diabetes Institute, Melbourne, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Linking Physical Activity to Breast Cancer Risk via Insulin/Insulin-Like Growth Factor Signaling System, Part 1: The Effect of Physical Activity on the Insulin/Insulin-Like Growth Factor Signaling System.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
-
Linking Physical Activity to Breast Cancer Risk via the Insulin/Insulin-like Growth Factor Signaling System, Part 2: The Effect of Insulin/Insulin-like Growth Factor Signaling on Breast Cancer Risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology
Carlie Delaine
2 publications dans cette catégorie
Affiliations :
- Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone.
Biomolecules 2021-11-29
-
How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor.
Structure (London, England : 1993) 2022-06-03
Briony E Forbes
2 publications dans cette catégorie
Affiliations :
- Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA 5042, Australia.
Publications dans "Activité de type insulinique non suppressible" :
-
Identification, Synthesis, Conformation and Activity of an Insulin-like Peptide from a Sea Anemone.
Biomolecules 2021-11-29
-
How insulin-like growth factor I binds to a hybrid insulin receptor type 1 insulin-like growth factor receptor.
Structure (London, England : 1993) 2022-06-03
Sources (10000 au total)
Differential influence of YAP1 and TAZ on differentiation of intestinal epithelial cell: A review.
Intestinal cell stemness, proliferation and differentiation are complex processes all occurring in distinct compartments of the crypt that need to be closely regulated to ensure proper epithelial rene...
Development and In Vitro Differentiation of Schwann Cells.
Schwann cells are glial cells of the peripheral nervous system. They exist in several subtypes and perform a variety of functions in nerves. Their derivation and culture in vitro are interesting for a...
Ranking reprogramming factors for cell differentiation.
Transcription factor over-expression is a proven method for reprogramming cells to a desired cell type for regenerative medicine and therapeutic discovery. However, a general method for the identifica...
Organization of cortical microtubules in differentiated cells.
The microtubule cytoskeleton plays a critical role in a variety of cellular activities, and its structures and functions have been extensively studied. However, little is known about cell differentiat...
Connexin 43 and cell culture substrate differentially regulate OCY454 osteocytic differentiation and signaling to primary bone cells.
Connexin 43 (Cx43), the predominate gap junction protein in bone, is essential for intercellular communication and skeletal homeostasis. Previous work suggests that osteocyte-specific deletion of Cx43...
Phagocytosing differentiated cell-fragments is a novel mechanism for controlling somatic stem cell differentiation within a short time frame.
Stem cells undergo cytokine-driven differentiation, but this process often takes longer than several weeks to complete. A novel mechanism for somatic stem cell differentiation via phagocytosing 'model...
Differential cell composition and split epidermal differentiation in human palm, sole, and hip skin.
Palmoplantar skin is structurally and functionally unique, but the transcriptional programs driving this specialization are unclear. Here, we use bulk and single-cell RNA sequencing of human palm, sol...
iPSC-Derived Macrophages: The Differentiation Protocol Affects Cell Immune Characteristics and Differentiation Trajectories.
The generation of human macrophages from induced pluripotent stem cells (iMacs) is a rapidly developing approach used to create disease models, screen drugs, study macrophage-pathogen interactions and...
Peptide Regulation of Chondrogenic Stem Cell Differentiation.
The search for innovative ways to treat osteoarthritis (OA) is an urgent task for molecular medicine and biogerontology. OA leads to disability in persons of middle and older age, while safe and effec...