Cold Spring Harbor Laboratory, 1 Bungtown Rd, Cold Spring Harbor, NY 11724, USA.
Present address: Institute for Quantitative Biosciences, the University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo, 1130032, Japan.
Present address: Department of Life Sciences, Graduate School of Arts and Sciences, the University of Tokyo, 3-8-1 Komaba, Meguro-ku, Tokyo, 1538902, Japan.
Food Quality Perception & Society Team, iSENSE Lab, Department of Food Science, Aarhus University, Aarhus, Denmark; Sino-Danish College (SDC), University of Chinese Academy of Sciences, Beijing, China.
Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.
Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USAuoszczap@andrew.cmu.edu, hellerl@andrew.cmu.edu, seojunj@andrew.cmu.edu, banance@andrew.cmu.edu.
Department of Psychology, Carnegie Mellon University, Pittsburgh, Pennsylvania 15213, USA.
Center for the Neural Basis of Cognition, Pittsburgh, Pennsylvania 15213, USAuoszczap@andrew.cmu.edu, hellerl@andrew.cmu.edu, seojunj@andrew.cmu.edu, banance@andrew.cmu.edu.
Consultant Neurologist & Honorary Clinical Associate Professor of Neurology, Department of Neurology, Leeds General Infirmary, Great George Street, Leeds LS1 3EX, UK. Electronic address: melissamaguire@nhs.net.
International Islamic University Malaysia, Kulliyyah of Allied Health Sciences, Department of Audiology and Speech Language Pathology, Kuantan, Pahang, Malaysia.
International Islamic University Malaysia, Kulliyyah of Allied Health Sciences, Department of Audiology and Speech Language Pathology, Kuantan, Pahang, Malaysia. sarahrahmat@iium.edu.my.
International Islamic University Malaysia, Kulliyyah of Allied Health Sciences, Department of Audiology and Speech Language Pathology, Kuantan, Pahang, Malaysia.
International Islamic University Malaysia, Kulliyyah of Allied Health Sciences, Department of Optometry and Visual Sciences, Kuantan, Pahang, Malaysia.
Troponin elevation is frequently observed in various scenarios in the Emergency Department (ED), yet there is a paucity of studies investigating simultaneously measured high-sensitivity cardiac tropon...
All patients who underwent troponin testing at a single center were eligible for this study. Only patients with simultaneous samples with hs-cTnI (Siemens) and hs-cTnT (Roche) were included, regardles...
Analysis of 1987 samples from 1134 patients showed a significant correlation between hs-cTnT and hs-cTnI (r = 0.86, p < 0.01). Of these samples, 65% exceeded the upper reference limit (URL) for hs-cTn...
Elevated troponins above the URL were very common in this diverse cohort, particularly for hs-cTnT, which was twice as frequent compared to hs-cTnI, resulting in low specificity and PPV for AMI....
To examine the association of ultrasensitive cTnI (cardiac troponin I) with incident cardiovascular disease events (CVDs) in the primary prevention setting....
cTnI was analyzed in the baseline plasma (2008-2012) of CVD-free volunteers from the Paris Prospective Study III using a novel ultrasensitive immunoassay (Simoa Troponin-I 2.0 Kit, Quanterix, Lexingto...
The study population includes 9503 participants (40% women) aged 59.6 (6.3) years. cTnI was detected in 99.6% of the participants (median value=0.63 pg/mL, interquartile range, 0.39-1.09). After a med...
Ultrasensitive cTnI is an independent marker of CVD events in the primary prevention setting....
Cardiac vascular diseases, especially acute myocardial infarction (AMI), are one of the leading causes of death worldwide. Therefore cardio-specific biomarkers such as cardiac troponin I (cTnI) play a...
Elevations of high-sensitivity cardiac troponin (hs-cTn) concentrations not related to type 1 myocardial infarction are common in chest pain patients presenting to emergency departments. The discrimin...
We calculated the hs-cTn I/T ratio in 888 chest pain patients having hs-cTnI (Abbott Laboratories) or hs-cTnT (Roche Diagnostics) concentrations above the respective 99th percentile at 2 hours from pr...
The median hs-cTn I/T ratio was 3.45 (25th, 75th percentiles 1.80-6.59) in type 1 MI patients (n = 408 ☯46.0%]), 1.18 (0.81-1.90) in type 2 MI patients (n = 56 ☯6.3%]) and 0.67 (0.39-1.12) in patients...
The hs-cTn I/T ratio appears to be useful for early diagnosis of type 1 MI and its discrimination from type 2 MI in chest pain patients presenting with elevated hs-cTn. Differences in hs-cTn I/T ratio...
Cardiac surgeries are generally associated with high morbidity and mortality. To prevent any adverse outcomes, it is crucial to identify patients at risk of developing postoperative complications and ...
This systematic review was conducted in accordance with the Preferred Reporting Items for Systematic Review and Meta-Analysis guidelines. A thorough literature search was conducted over PubMed, clinic...
Following a comprehensive literature search, a total of 359 articles were obtained. Following a rigid screening and full-length review, only 13 studies met our inclusion criteria and were included. Th...
Troponin I has the potential to be used as a stand-alone predictor of surgical outcomes following coronary artery bypass grafting and valvular surgeries. However, supplementing it with other markers a...
Cardiac troponin I (cTnI) is one of the structural subunits of cardiac troponin complexes and a significant biomarker of acute myocardial infarction (AMI). Therefore, a sensitive detection of cTnI in ...
Coronavirus disease 2019 (COVID-19) can cause cardiac injury, probably associated with myocarditis and ischemia induced by the infection. Myocardial damage leads to the liberation of proinflammatory c...
To assess mortality associated with myocardial damage in hospitalized patients with COVID-19 confirmed by troponin I measurement....
Case-control study nested in a cohort of patients of a third-level hospital. Descriptive statistics were used to characterize the population. Qualitative variables were expressed as proportions and ra...
From June 2020 to August 2020, 28 patients who met the selection criteria were enrolled, out of which 15 had no myocardial damage and 13 had myocardial damage assessed by serum troponin measurement. A...
Mortality in patients with COVID-19 is associated with myocardial damage assessed by troponin I measurement....
High-sensitivity Troponin I (hs-cTnI) has largely replaced conventional troponin assays in an effort to improve detection of myocardial infarction. However, the mean displacement of hs-cTnI following ...
Between 2016 and 2018, 374 patients underwent non-emergent, isolated CABG. Pre-operative and 6 h post-operative hs-cTnI values were recorded as well as ECG, echocardiographic and angiographic data....
Of 374 patients, 151 (40.3%) had normal and 224 (59.7%) had elevated preoperative hs-cTnI. Patients with normal preoperative hs-cTnI had a mean 6 h hs-cTnI of 9193 ng/l or 270X the upper normal value....
We suggest hs-cTnI threshold of 80-fold in patients with normal pre-operative hs-cTnI and 2.7-fold in patients with elevated pre-operative hs-cTnI. These results have important implications for periop...
Background and Objectives: We aimed to compare the time to diagnosis for acute coronary syndromes using high-sensitivity troponin I (hsTnI) and conventional troponin I (TnI) in patients presenting to ...
