Titre : Équivalence thérapeutique

Équivalence thérapeutique : Questions médicales fréquentes

Termes MeSH sélectionnés :

International Classification of Functioning, Disability and Health
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"Symptômes sur Équivalence thérapeutique", "description": "Quels symptômes indiquent une non-équivalence ?\nComment reconnaître une réaction allergique ?\nQuels signes d'inefficacité observer ?\nLes symptômes varient-ils selon les traitements ?\nQuels symptômes nécessitent un avis médical ?", "url": "https://questionsmedicales.fr/mesh/D013810?mesh_terms=International+Classification+of+Functioning,+Disability+and+Health&page=9#section-symptômes" }, { "@type": "MedicalWebPage", "name": "Prévention", "headline": "Prévention sur Équivalence thérapeutique", "description": "Comment prévenir les erreurs de traitement ?\nQuelles sont les bonnes pratiques de prescription ?\nComment informer les patients sur l'équivalence ?\nQuels outils aident à la prévention des erreurs ?\nPourquoi est-il important de connaître l'équivalence ?", "url": "https://questionsmedicales.fr/mesh/D013810?mesh_terms=International+Classification+of+Functioning,+Disability+and+Health&page=9#section-prévention" }, { "@type": "MedicalWebPage", "name": "Traitements", "headline": "Traitements sur Équivalence thérapeutique", "description": "Quels traitements sont souvent équivalents ?\nComment choisir entre deux traitements équivalents ?\nLes traitements équivalents ont-ils les mêmes effets ?\nComment évaluer la sécurité des traitements ?\nLes traitements équivalents nécessitent-ils des doses différentes ?", "url": "https://questionsmedicales.fr/mesh/D013810?mesh_terms=International+Classification+of+Functioning,+Disability+and+Health&page=9#section-traitements" }, { "@type": "MedicalWebPage", "name": "Complications", "headline": "Complications sur Équivalence thérapeutique", "description": "Quelles complications peuvent survenir avec des traitements équivalents ?\nComment gérer les complications liées aux traitements ?\nLes complications sont-elles prévisibles ?\nQuels sont les signes d'une complication grave ?\nComment prévenir les complications ?", "url": "https://questionsmedicales.fr/mesh/D013810?mesh_terms=International+Classification+of+Functioning,+Disability+and+Health&page=9#section-complications" }, { "@type": "MedicalWebPage", "name": "Facteurs de risque", "headline": "Facteurs de risque sur Équivalence thérapeutique", "description": "Quels facteurs augmentent le risque d'échec thérapeutique ?\nComment l'adhérence au traitement affecte-t-elle l'équivalence ?\nLes antécédents médicaux influencent-ils l'équivalence ?\nQuels facteurs environnementaux jouent un rôle ?\nComment évaluer les facteurs de risque ?", "url": "https://questionsmedicales.fr/mesh/D013810?mesh_terms=International+Classification+of+Functioning,+Disability+and+Health&page=9#section-facteurs de risque" } ] }, { "@type": "FAQPage", "mainEntity": [ { "@type": "Question", "name": "Comment évaluer l'équivalence thérapeutique ?", "position": 1, "acceptedAnswer": { "@type": "Answer", "text": "L'évaluation se fait par des études cliniques comparatives et des méta-analyses." } }, { "@type": "Question", "name": "Quels tests sont utilisés pour l'équivalence ?", "position": 2, "acceptedAnswer": { "@type": "Answer", "text": "Des tests de bioéquivalence et des études de pharmacocinétique sont couramment utilisés." } }, { "@type": "Question", "name": "Quelles sont les normes d'évaluation ?", "position": 3, "acceptedAnswer": { "@type": "Answer", "text": "Les normes incluent des critères de sécurité, d'efficacité et de qualité des médicaments." } }, { "@type": "Question", "name": "Qui réalise les évaluations d'équivalence ?", "position": 4, "acceptedAnswer": { "@type": "Answer", "text": "Les agences de régulation, comme l'ANSM, et des chercheurs indépendants effectuent ces évaluations." } }, { "@type": "Question", "name": "Quels sont les critères d'inclusion ?", "position": 5, "acceptedAnswer": { "@type": "Answer", "text": "Les critères incluent la population cible, les indications et les méthodes de traitement." } }, { "@type": "Question", "name": "Quels symptômes indiquent une non-équivalence ?", "position": 6, "acceptedAnswer": { "@type": "Answer", "text": "Des effets indésirables ou une efficacité réduite peuvent signaler une non-équivalence." } }, { "@type": "Question", "name": "Comment reconnaître une réaction allergique ?", "position": 7, "acceptedAnswer": { "@type": "Answer", "text": "Les symptômes incluent éruption cutanée, démangeaisons, et gonflement après administration." } }, { "@type": "Question", "name": "Quels signes d'inefficacité observer ?", "position": 8, "acceptedAnswer": { "@type": "Answer", "text": "L'absence d'amélioration des symptômes après un traitement peut indiquer une inefficacité." } }, { "@type": "Question", "name": "Les symptômes varient-ils selon les traitements ?", "position": 9, "acceptedAnswer": { "@type": "Answer", "text": "Oui, les traitements peuvent provoquer des symptômes différents selon leur composition." } }, { "@type": "Question", "name": "Quels symptômes nécessitent un avis médical ?", "position": 10, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes graves ou persistants après un traitement doivent être évalués par un médecin." } }, { "@type": "Question", "name": "Comment prévenir les erreurs de traitement ?", "position": 11, "acceptedAnswer": { "@type": "Answer", "text": "La vérification des prescriptions et l'éducation des patients sont essentielles." } }, { "@type": "Question", "name": "Quelles sont les bonnes pratiques de prescription ?", "position": 12, "acceptedAnswer": { "@type": "Answer", "text": "Utiliser des protocoles standardisés et vérifier les allergies des patients." } }, { "@type": "Question", "name": "Comment informer les patients sur l'équivalence ?", "position": 13, "acceptedAnswer": { "@type": "Answer", "text": "Fournir des brochures et des consultations pour expliquer les options de traitement." } }, { "@type": "Question", "name": "Quels outils aident à la prévention des erreurs ?", "position": 14, "acceptedAnswer": { "@type": "Answer", "text": "Des logiciels de gestion des prescriptions et des alertes de sécurité peuvent aider." } }, { "@type": "Question", "name": "Pourquoi est-il important de connaître l'équivalence ?", "position": 15, "acceptedAnswer": { "@type": "Answer", "text": "Cela permet de choisir le traitement le plus approprié et de réduire les coûts." } }, { "@type": "Question", "name": "Quels traitements sont souvent équivalents ?", "position": 16, "acceptedAnswer": { "@type": "Answer", "text": "Les génériques et les médicaments de marque pour la même indication sont souvent équivalents." } }, { "@type": "Question", "name": "Comment choisir entre deux traitements équivalents ?", "position": 17, "acceptedAnswer": { "@type": "Answer", "text": "Le choix dépend de la tolérance, du coût et des préférences du patient." } }, { "@type": "Question", "name": "Les traitements équivalents ont-ils les mêmes effets ?", "position": 18, "acceptedAnswer": { "@type": "Answer", "text": "Ils doivent avoir des effets cliniques similaires, mais peuvent différer en effets secondaires." } }, { "@type": "Question", "name": "Comment évaluer la sécurité des traitements ?", "position": 19, "acceptedAnswer": { "@type": "Answer", "text": "La sécurité est évaluée par des études cliniques et des rapports d'effets indésirables." } }, { "@type": "Question", "name": "Les traitements équivalents nécessitent-ils des doses différentes ?", "position": 20, "acceptedAnswer": { "@type": "Answer", "text": "Pas nécessairement, mais des ajustements peuvent être nécessaires selon le patient." } }, { "@type": "Question", "name": "Quelles complications peuvent survenir avec des traitements équivalents ?", "position": 21, "acceptedAnswer": { "@type": "Answer", "text": "Des complications peuvent inclure des réactions allergiques ou des interactions médicamenteuses." } }, { "@type": "Question", "name": "Comment gérer les complications liées aux traitements ?", "position": 22, "acceptedAnswer": { "@type": "Answer", "text": "Il est crucial d'arrêter le traitement et de consulter un professionnel de santé." } }, { "@type": "Question", "name": "Les complications sont-elles prévisibles ?", "position": 23, "acceptedAnswer": { "@type": "Answer", "text": "Certaines complications peuvent être prévisibles, surtout avec des antécédents médicaux." } }, { "@type": "Question", "name": "Quels sont les signes d'une complication grave ?", "position": 24, "acceptedAnswer": { "@type": "Answer", "text": "Des symptômes tels que des douleurs thoraciques ou des difficultés respiratoires sont alarmants." } }, { "@type": "Question", "name": "Comment prévenir les complications ?", "position": 25, "acceptedAnswer": { "@type": "Answer", "text": "Un suivi régulier et une communication ouverte avec le médecin sont essentiels." } }, { "@type": "Question", "name": "Quels facteurs augmentent le risque d'échec thérapeutique ?", "position": 26, "acceptedAnswer": { "@type": "Answer", "text": "Des facteurs comme l'âge, les comorbidités et l'adhérence au traitement influencent le risque." } }, { "@type": "Question", "name": "Comment l'adhérence au traitement affecte-t-elle l'équivalence ?", "position": 27, "acceptedAnswer": { "@type": "Answer", "text": "Une mauvaise adhérence peut réduire l'efficacité, rendant l'équivalence difficile à évaluer." } }, { "@type": "Question", "name": "Les antécédents médicaux influencent-ils l'équivalence ?", "position": 28, "acceptedAnswer": { "@type": "Answer", "text": "Oui, des antécédents de réactions aux médicaments peuvent affecter le choix du traitement." } }, { "@type": "Question", "name": "Quels facteurs environnementaux jouent un rôle ?", "position": 29, "acceptedAnswer": { "@type": "Answer", "text": "Des facteurs comme l'alimentation, le mode de vie et l'exposition à des toxines peuvent influencer." } }, { "@type": "Question", "name": "Comment évaluer les facteurs de risque ?", "position": 30, "acceptedAnswer": { "@type": "Answer", "text": "Une évaluation complète de l'historique médical et des habitudes de vie est nécessaire." } } ] } ] }

Sources (10000 au total)

An International Classification of Functioning, Disability and Health Model-Based Analysis of Suicidal Ideation among 9920 Community-Dwelling Korean Older Adults.

Many complex factors contribute to suicide in older adults. The suicidal ideation that precedes suicide is an especially direct predictor of suicide. This study aimed to identify the effects between v... This study used data from 9920 community-dwelling older adults who completed a national survey in 2020 to classify predictors of suicidal ideation (e.g., depression, subjective health status, sociodem... Gender, education level, economic level, age, IADL, relationship satisfaction with a child, depression, and the number of chronic diseases significantly affected suicidal ideation, while age, employme... It was found that depression was the most direct and mediating factor in suicidal ideation among many factors affecting the suicidal ideation of community-dwelling older adults. Additional studies sho...

Machine Learning Based Linking of Patient Reported Outcome Measures to WHO International Classification of Functioning, Disability, and Health Activity/Participation Categories.

In the primary and secondary medical health sector, patient reported outcome measures (PROMs) are widely used to assess a patient's disease-related functional health state. However, the World Health O... This research sought to optimize machine learning (ML) methods that fully and automatically link information collected from PROMs in persons with unspecific chronic low back pain (cLBP) to limitations... A total of 806 patients with cLBP completed a comprehensive set of validated PROMs and were interviewed by clinical psychologists who assessed patients' performance in activity limitations and restric... Compared to a recently developed ML linking method, receiver operating characteristic curve (ROC-AUC) values for the novel RF methods showed overall improved performance, with AUC values ranging from ... Findings suggest that our optimized ML based methods more accurately predict the presence or absence of limitations and restrictions listed in ICF core categories for cLBP. In addition, this accurate ...

An analysis of caregiver burden assessments using the International Classification of Functioning, Disability, and health (ICF): what aspects of burden are measured, and what is missing?

To determine if commonly used caregiver burden assessments, Zarit Burden Interview(ZBI), Caregiver Reaction Assessment Scale(CRA), Caregiver Burden Inventory(CBI), and Caregiver Strain Index(CSI), pro... Meaningful concepts, identified from these assessments, were linked to the most appropriate and precise International Classification of Functioning, Disability, and Health (ICF) code by experienced co... A total of 120 meaningful concepts identified from 83 items, represented three of the four ICF domains: 1)... Linking commonly used caregiver burden assessments to the ICF and comparing the results to the epidemiologic factors of caregiver burden suggests that the assessments may not be capturing many of the ...

Functional patient-reported outcome measures after hip or knee arthroplasty: A systematic review and content analysis using the International Classification of Functioning, Disability and Health (ICF).

This systematic review aimed to identify the existing patient-reported outcome measures (PROMs) used in hip or knee arthroplasty for adults with osteoarthritis and assess their content validity using ... Four databases were systematically searched to identify disease or joint-specific PROMs evaluating function after hip or knee arthroplasty. Two reviewers independently evaluated the content of PROMs b... From 449 studies included in this review, 50 PROMs were identified. The mobility chapter of activities and participation was the most common component, followed by sensory function and pain chapter of... Even though our search identified 50 specific PROMs, there remain gaps in content related to activity and participation coverage. By providing a content analysis of the PROMs used after hip or knee ar...

Which body functions and activities matter for stroke patients? Study protocol for best-Worst scalings to value core elements of the International Classification of Functioning, Disability and Health.

Stroke is a common, serious, and disabling healthcare problem with increasing incidence and prevalence. Following a stroke, identifying the factors associated with decisions about rehabilitation inter... In this study we conduct three best-worst scaling (BWS) experiments to value body function and activities from patients' and public perspective. Out of all ICF dimensions this research covers health c... The research will add to the current literature on clinical decision-making in stroke rehabilitation and the value of certain body functions as well as related activities in neurorehabilitation. Moreo...

Examining the content validity of the Comprehensive Assessment of Functioning for Mental Illness-Subjective Version (CAMI-S) with reference to the framework of the International Classification of Functioning, Disability, and Health (ICF).

To support the achievement of life goals and social participation of persons with mental illness, based on the World Health Organization's International Classification of Functioning, Disability, and ... Focus group interviews on the items to be included were conducted with Group A. A draft scale was constructed by extracting articles mentioning factors for social participation and recovery for each I... The interviews revealed subjective experience items. The draft scale had 81 items (physical and mental functions, 10; activities, 23; participation, 24; environment, 12; individuals, six; and subjecti... The CAMI-S helped participants ascertain patients' strengths and weaknesses. Its reliability and validity will be verified through a large-scale survey in the future....

Performance of the Activities and Participation component of International Classification of Functioning, Disability and Health Sleep Disorders Brief Core Set in patients with obstructive sleep apnea.

Limitation of daily activities and impairment of working memory have received less attention in the clinical diagnosis and prognostic assessment of obstructive sleep apnea (OSA). In this study, the Ac... A total of 221 subjects were recruited into this cross-sectional study. ICF Sleep Disorders Brief Core Set, polysomnography, and neuropsychological tests were applied for data acquisition. Data analys... The scores for the component Activities and Participation were significantly different between the no OSA/OSA group, and were elevated as the severity of OSA increased. Scores were positively correlat... The Activities and Participation component of the ICF Sleep Disorders Brief Core Set could have the potential to predict the impairment of attention and work ability in OSA patients. It provides a new...

Holistic assessment of cochlear implant outcomes using the international classification of functioning disability and health model: data analysis of a longitudinal prospective multicenter study.

To study outcome after cochlear implantation using the Cochlear Implant (CI) outcome assessment protocol based on the International Classification of Functioning, Disability and Health (ICF) model (CI... Raw data of a prospective, longitudinal, multicenter study was analyzed. Seventy-two CI candidates were assessed preoperatively and six months postoperatively using the CI-ICF protocol. Following tool... There was a significant improvement of speech discrimination in quiet (p = 0.015; p < 0.001) and in noise (p = 0.041; p < 0.001), sound detection (p < 0.001), tinnitus (p = 0.026), listening (p < 0.00... This study highlights the positive impact of cochlear implantation on auditory performance, communication, and subjective well-being. The CI-ICF protocol provides a holistic and comprehensive view of ...

Functioning Problems Associated with Health Conditions with Greatest Disease Burden in South Africa: A Scoping Review.

A notable rise in health-related disability for which evidence-based rehabilitation is beneficial is evident in low-to-middle income countries. This scoping review aimed to systematically identify and...

Development and appropriateness of a scoring method for International Classification of Functioning, Disabilities, and Health assessment in older patients with heart failure: a Delphi survey of expert panel in Japan.

The number of older patients with heart failure (HF) is increasing in Japan and has become a social problem. There is an urgent need to develop a comprehensive assessment methodology based on the comm... Cross-sectional survey. We applied the RAND/University of California at Los Angeles (UCLA) Appropriateness Method with a modified Delphi method.... We included a panel of 26 multidisciplinary experts on HF care consisting of home physicians, cardiovascular physicians, care managers, nurses, physical therapists, a pharmacist, occupational therapis... We conducted a literature review of ICF linking rules and developed a questionnaire on scoring methods linked to ICF categories in older people with HF. In the Delphi rounds, we sent the expert panel ... A total of 21 panel members responded to all the Delphi rounds. In the first Delphi round, six question items in four ICF categories did not reach a consensus of 'Agreement', but the result of our mod... The ICF-based scoring method for older people with HF developed in this study was found to be appropriate. Future work is needed to clarify whether comprehensive assessment and information sharing bas...