Titre : Vinblastine

Vinblastine : Questions médicales fréquentes

Termes MeSH sélectionnés :

Manometry

Questions fréquentes et termes MeSH associés

Diagnostic 2

#1

Comment la vinblastine est-elle utilisée dans le diagnostic du cancer ?

La vinblastine n'est pas un outil de diagnostic, mais un traitement pour les cancers diagnostiqués.
Vinblastine Cancer Diagnostic médical
#2

Quels tests précèdent l'administration de vinblastine ?

Des tests sanguins et d'imagerie sont effectués pour évaluer la maladie avant le traitement.
Tests de laboratoire Imagerie médicale Vinblastine

Symptômes 2

#1

Quels sont les effets secondaires courants de la vinblastine ?

Les effets secondaires incluent nausées, vomissements, fatigue et perte de cheveux.
Effets secondaires Vinblastine Nausées
#2

La vinblastine provoque-t-elle des douleurs ?

Elle peut causer des douleurs musculaires ou articulaires, mais ce n'est pas systématique.
Douleur Vinblastine Effets indésirables

Prévention 2

#1

La vinblastine a-t-elle un rôle préventif dans le cancer ?

Non, la vinblastine est un traitement et ne prévient pas le développement du cancer.
Prévention du cancer Vinblastine Traitement
#2

Peut-on prévenir les effets secondaires de la vinblastine ?

Des médicaments antiémétiques peuvent aider à réduire les nausées causées par la vinblastine.
Effets secondaires Vinblastine Médicaments antiémétiques

Traitements 2

#1

Dans quels types de cancer la vinblastine est-elle utilisée ?

Elle est utilisée pour traiter les lymphomes, le cancer du poumon et le cancer du testicule.
Lymphome Cancer du poumon Vinblastine
#2

Comment la vinblastine est-elle administrée ?

La vinblastine est généralement administrée par injection intraveineuse sous supervision médicale.
Administration intraveineuse Vinblastine Traitement du cancer

Complications 2

#1

Quelles complications peuvent survenir avec la vinblastine ?

Des complications incluent des infections, des saignements et des problèmes neurologiques.
Complications Vinblastine Infections
#2

La vinblastine peut-elle affecter la moelle osseuse ?

Oui, la vinblastine peut entraîner une dépression de la moelle osseuse, réduisant les globules blancs.
Moelle osseuse Vinblastine Dépression médullaire

Facteurs de risque 2

#1

Qui est à risque d'effets indésirables avec la vinblastine ?

Les patients avec des antécédents de maladies cardiaques ou hépatiques sont à risque accru.
Facteurs de risque Vinblastine Maladies cardiaques
#2

Les enfants peuvent-ils prendre de la vinblastine ?

Oui, la vinblastine peut être administrée aux enfants, mais avec précaution et surveillance.
Vinblastine Pédiatrie Traitement du cancer
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Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale


Validation scientifique effectuée le 04/02/2025

Contenu vérifié selon les dernières recommandations médicales

Auteurs principaux

Eric Bouffet

2 publications dans cette catégorie

Affiliations :
  • Programme in Developmental and Stem Cell Biology, Division of Haematology/Oncology, Hospital for Sick Children, Toronto, Ontario, Canada.

Yaser Hassan Dewir

2 publications dans cette catégorie

Affiliations :
  • Plant Production Department, College of Food and Agriculture Sciences, King Saud University, Riyadh 11451, Saudi Arabia.

Sarah E O'Connor

2 publications dans cette catégorie

Affiliations :
  • Department of Natural Product Biosynthesis, Max Planck Institute for Chemical Ecology, Jena, Germany.

G A Amos Burke

2 publications dans cette catégorie

Affiliations :
  • Cambridge University Hospitals NHS Foundation Trust, Addenbrooke's Hospital, Cambridge, UK.

Riccardo Finotello

2 publications dans cette catégorie

Affiliations :
  • Department of Small Animal Clinical Sciences, Department of Veterinary Anatomy Physiology and Pathology, Institute of Infection Veterinary and Ecological Sciences, University of Liverpool, Chester High Rd, Neston CH64 7TE, UK.

Yoshihiro Nishida

2 publications dans cette catégorie

Affiliations :
  • Department of Rehabilitation Medicine, Nagoya University Hospital, Nagoya, Japan.
  • Department of Orthopaedic Surgery, Nagoya University Hospital, Nagoya, Japan.

Shunsuke Hamada

2 publications dans cette catégorie

Affiliations :
  • Department of Orthopaedic Surgery, Nagoya University Hospital, Nagoya, Japan.

Tomohisa Sakai

2 publications dans cette catégorie

Affiliations :
  • Department of Orthopaedic Surgery, Nagoya University Hospital, Nagoya, Japan.

Hiroshi Koike

2 publications dans cette catégorie

Affiliations :
  • Department of Orthopaedic Surgery, Nagoya University Hospital, Nagoya, Japan.

Magdalena Markowicz-Piasecka

2 publications dans cette catégorie

Affiliations :
  • Laboratory of Bioanalysis, Department of Pharmaceutical Chemistry, Drug Analysis and Radiopharmacy, Medical University of Lodz, ul. Muszyńskiego 1, 90-151, Lodz, Poland; Department of Applied Pharmacy, Medical University of Lodz, ul. Muszyńskiego 1, 90-151, Lodz, Poland.

Sources (349 au total)

Effect of Caffeine on Colonic Manometry in Children.

Coffee and caffeinated products have been widely consumed for many centuries. Previous adult studies have suggested that both coffee and decaffeinated beverages induce colonic motility. However, no st... A prospective study of pediatric patients undergoing standard colonic motility testing that were able to consume caffeinated coffee, decaffeinated coffee, and caffeine tablet during colonic manometry.... Thirty-eight patients were recruited, 22 of which were excluded, 11 due to abnormal studies (no HAPC seen in response to intraluminal response to bisacodyl), and 11 due to inability to consume all stu... Caffeine is indeed a colonic stimulant; however, other components of caffeinated and non-caffeinated beverages likely induce colonic response and require further evaluation for possible use as a colon...

Components of high-resolution manometry that change surgical decisions.

High-resolution manometry (HRM) is vital in evaluating patients for surgery at the gastroesophageal (GE) junction. Previously, we reported manometry alters surgery choices at the GE junction over 50% ... We collected data on pre-operative symptoms for patients undergoing HRM studies from 2012 to 2016, i.e., Upper GI X-rays, 48-h pH studies, DeMeester scores, upper endoscopy, and biopsy reports. HRM re... 298 HRM studies were initially identified; 114 met search criteria. Overall, HRM altered the planned procedure in 50.9% of cases (n = 58), with abnormal motility in 54.4% (62/114) cases. Abnormal moti... This study demonstrates the impact of identifying abnormal motility via the Chicago classification and factors like DCI on surgical choice at the GE junction....

Safety and Tolerability of High-Resolution Esophageal Manometry in Children and Adults.

While high-resolution manometry (HRM) is widely accepted as a safe procedure, no study has assessed the safety profile of HRM in clinical practice. This study aimed to determine the safety and tolerab... We obtained HRM procedure reports, demographics, and clinical data (2005-2022) at a tertiary center using electronic chart review. Our primary outcome was HRM tolerability. Multivariable regression wa... A total of 5,107 patients (60.3% female) were included. Of them, 5,050 patients (98.9%) tolerated HRM well and 57 patients (1.1%) did not. Age had a statistically significant effect on tolerance: thos... HRM is safe and well-tolerated with approximately 1 in every 100 patients being unable to tolerate HRM. Intolerance was more commonly seen in children and seniors due to minor symptoms of discomfort w...

Reproducibility of high-resolution manometry among healthy and constipated persons.

Although high-resolution manometry (HR_ARM) is commonly used to diagnose defecatory disorders, its intraindividual day-to-day reproducibility is unknown. Since these measurements entail voluntary effo... In 22 healthy women (35 years [14] mean [SD]) and 53 constipated patients (42 years [13], 46 women), the rectal balloon expulsion time (BET), and anorectal pressures were measured with HR_ARM on 2 day... Among constipated patients, the anal resting (mean CCC [95%CI] 0.62 [0.43-0.76]) and squeeze pressures (CCC 0.65 [0.47-0.79]), rectoanal gradient during evacuation (CCC 0.42 [0.17-0.62]), and rectal s... While HR_ARM variables and the BET are reproducible within healthy and constipated persons, the outcome on repeat testing differed in 79% of constipated patients....

Optimizing the Utility of Anorectal Manometry for Diagnosis and Therapy: A Roundtable Review and Recommendations.

Anorectal manometry (ARM) is a comprehensive diagnostic tool for evaluating patients with constipation, fecal incontinence, or anorectal pain; however, it is not widely utilized for reasons that remai... Leaders in medical and surgical gastroenterology and physical therapy with interest in anorectal disorders were surveyed regarding practice patterns and utilization of these technologies. Subsequently... ARM identifies key pathophysiological abnormalities such as dyssynergic defecation, anal sphincter weakness, or rectal sensory dysfunction, and is a critical component of biofeedback therapy, an evide... Overcoming these challenges with appropriate education, training, collaborative research, and evidence-based guidelines for ARM testing and biofeedback therapy could significantly enhance patient care...

Diagnosing Mild Forms of Anorectal Malformation With Anorectal Manometry: A Prospective Study.

Rectoperineal congenital anorectal malformations (CARMs) are diagnosed by examining the perineum, combined with electric stimulation (ES) of the anal sphincter performed under anesthesia. This procedu... We prospectively included 66 patients younger than 24 months who presented with constipation and were suspected of CARM, idiopathic constipation, or Hirschsprung disease. The patients were assessed be... Of the 51 patients who underwent both 3D-HRAM and ES, we observed that patients with rectoperineal CARM revealed a pressure gap along the anterior part of the anal sphincter. Based on this observation... We consider 3D-HRAM a reliable tool for diagnosing and excluding rectoperineal CARM. Using this method in patients suspected of CARM might keep infants from undergoing unnecessary interventions requir...

Post-operative colonic manometry in children with anorectal malformations: A systematic review.

Children with anorectal malformations may experience constipation and fecal incontinence following repair. The contribution of altered anorectal function to these persistent symptoms is relatively int... The purpose of this systematic review was to synthesize the available evidence regarding post-operative colonic motility in children with anorectal malformations and evaluate the reported equipment an...

Automated extraction of anorectal pressures from high-resolution manometry reports.

During high-resolution anorectal manometry (HR_ARM), the raw data are converted into software-derived summary variables (e.g., rectoanal gradient during evacuation) that capture only a snapshot of the... Anorectal pressures at rest, during anal squeeze, and evacuation were measured with HR_ARM in 180 women, among whom 60 each were healthy, had DD, or fecal incontinence. A reverse engineering approach ... Anorectal pressures summarized by the software and a reverse engineering method were highly concordant for anal resting (CCC [95% CI], 0.98 [0.97, 0.99]) and squeeze pressures (0.99 [0.99, 0.99) and t... Anorectal pressures can be accurately determined from pressure topography images in HR_ARM reports. In future, this reverse engineering approach can be harnessed to compile large HR_ARM datasets acros...