Comment diagnostiquer une intoxication aux xanthènes ?

Le diagnostic repose sur l'historique d'exposition et des tests sanguins spécifiques.

Quels tests sont utilisés pour détecter les xanthènes ?

Des analyses chromatographiques comme la HPLC sont couramment utilisées.

Quels symptômes indiquent une exposition aux xanthènes ?

Les symptômes incluent des nausées, des vertiges et des troubles neurologiques.

Les xanthènes peuvent-ils être détectés dans l'urine ?

Oui, des tests urinaires peuvent révéler la présence de xanthènes.

Quel rôle joue l'historique médical dans le diagnostic ?

L'historique aide à identifier les expositions antérieures aux xanthènes.

Quels sont les symptômes courants d'une exposition aux xanthènes ?

Les symptômes incluent des maux de tête, des nausées et des troubles de la vision.

Les xanthènes provoquent-ils des réactions allergiques ?

Oui, certaines personnes peuvent développer des réactions allergiques aux xanthènes.

Comment les xanthènes affectent-ils le système nerveux ?

Ils peuvent provoquer des troubles neurologiques comme des convulsions ou des tremblements.

Les symptômes varient-ils selon le type de xanthène ?

Oui, les symptômes peuvent varier selon la structure chimique des xanthènes.

Les xanthènes affectent-ils la peau ?

Oui, une exposition cutanée peut entraîner des irritations ou des éruptions.

Comment prévenir l'exposition aux xanthènes ?

Évitez les produits contenant des xanthènes et portez des équipements de protection.

Les travailleurs doivent-ils être formés sur les xanthènes ?

Oui, une formation sur les risques et la manipulation sécurisée est essentielle.

Quelles mesures de sécurité doivent être prises en laboratoire ?

Utilisez des hottes, des gants et des lunettes de protection lors de la manipulation.

Les xanthènes sont-ils réglementés ?

Oui, leur utilisation est souvent réglementée pour protéger la santé publique.

Comment informer le public sur les dangers des xanthènes ?

Des campagnes de sensibilisation et des brochures d'information peuvent être utiles.

Quel traitement est recommandé en cas d'intoxication aux xanthènes ?

Le traitement inclut l'élimination de l'exposition et des soins symptomatiques.

Des antidotes existent-ils pour les xanthènes ?

Actuellement, il n'existe pas d'antidote spécifique pour les xanthènes.

Comment traiter les symptômes neurologiques causés par les xanthènes ?

Des médicaments anticonvulsivants peuvent être utilisés pour gérer les symptômes.

Les soins de soutien sont-ils nécessaires ?

Oui, des soins de soutien sont souvent nécessaires pour les cas graves.

Peut-on utiliser des traitements naturels contre les xanthènes ?

Il n'existe pas de preuves solides pour des traitements naturels efficaces.

Quelles complications peuvent survenir après une exposition aux xanthènes ?

Des complications neurologiques et dermatologiques peuvent se développer.

Les xanthènes peuvent-ils causer des maladies chroniques ?

Une exposition prolongée peut augmenter le risque de maladies chroniques.

Y a-t-il des effets à long terme des xanthènes ?

Oui, des effets à long terme incluent des troubles cognitifs et des problèmes de santé.

Les xanthènes peuvent-ils affecter la reproduction ?

Certaines études suggèrent qu'ils peuvent avoir des effets néfastes sur la reproduction.

Comment gérer les complications liées aux xanthènes ?

Un suivi médical régulier et des traitements symptomatiques sont recommandés.

Qui est le plus à risque d'exposition aux xanthènes ?

Les travailleurs dans l'industrie chimique et les laboratoires sont les plus à risque.

Les enfants sont-ils plus vulnérables aux xanthènes ?

Oui, les enfants peuvent être plus sensibles aux effets toxiques des xanthènes.

Quels facteurs environnementaux augmentent le risque ?

La pollution et l'exposition à des produits chimiques augmentent le risque.

Les antécédents médicaux influencent-ils le risque ?

Oui, des antécédents de maladies respiratoires ou neurologiques augmentent le risque.

Les habitudes de vie jouent-elles un rôle dans le risque ?

Oui, des habitudes comme le tabagisme peuvent augmenter la vulnérabilité aux xanthènes.

Xanthènes - Informations médicales vérifiées

Classification of Local Recurrence After Nipple-Sparing Mastectomy Based on Location: The Features of Nipple-Areolar Recurrence Differ from Those of Other Local Recurrences.

Mar 2023

DOI: 10.1245/s10434-022-12760-1 PMID: 36371582

Little information is available about the clinical and pathologic characteristics of local recurrence (LR) after nipple-sparing mastectomy according to the locations of LR.... This study classified 99 patients into the following two groups according to the location of LR after nipple-sparing mastectomy: nipple-areolar recurrence (NAR) group and other locations of LR (oLR) g... For about half of the patients (44.4 %) with NAR, the primary cancer was estrogen receptor (ER)-negative and human epidermal growth factor receptor 2 (HER2)-positive. Conversely, in most of the patien... This multi-institutional retrospective study demonstrated that the features of NAR, such as the characteristics of the primary and recurrent tumors and the prognostic factors after LR resection, were ...

Humans Female Breast Neoplasms Mastectomy Nipples +4 autres

Feasibility of local therapy for recurrent pancreatic cancer.

Sep 2022

DOI: 10.1016/j.pan.2022.05.004 PMID: 35641368

Despite advances in perioperative management, recurrence after curative pancreatectomy is a critical issue in the treatment of pancreatic ductal adenocarcinoma (PDAC). The significance of local therap... We reviewed the medical records of patients with PDAC who underwent curative resection at our institution between January 2009 and December 2019. We examined the patterns of relapse and assessed the c... A total of 246 patients with PDAC who underwent R0 or R1 resection were included in this study. The 3-year overall survival (OS) rate was 39.8%, and the 1-year recurrence-free survival rate was 51.2% ... Our results suggest that a multimodal approach may improve the clinical outcomes of patients with recurrent PDAC....

Adenocarcinoma Carcinoma, Pancreatic Ductal Feasibility Studies Humans Neoplasm Recurrence, Local +6 autres

Ultrasound Assessment of Skin Tumors Local Recurrence.

Oct 2023

DOI: 10.1002/jum.16255 PMID: 37195073

Skin cancer may recur at or around the surgical site despite wide excisions. Prompt clinical and sonographic detection of local recurrence is important since subjects with relapsing melanomas or nonme...

Humans Skin Neoplasms Skin Melanoma Ultrasonography +1 autres

Pathological determinants of outcome following resection of locally advanced or locally recurrent rectal cancer.

Nov 2023

DOI: 10.1016/j.ejso.2023.06.023 PMID: 37442715

Pathological factors that influence and predict survival following pelvic exenteration (PE) for locally advanced (LARC) or locally recurrent rectal cancer (LRRC), especially LRRC, remain poorly unders... A retrospective cohort study was performed for all patients undergoing a curative PE for LARC or LRRC between 2008 and 2021 at a tertiary referral UK specialist colorectal hospital. Cox regression ana... 388 patients were included in the analysis with 256 resections for LARC and 132 for LRRC. 62.4% of patients were male with a median age of 59 years (IQR 49-67). 247 (64%) partial pelvic exenterations ... A positive resection margin and poorly differentiated tumours are significant negative prognostic markers for survival and recurrence in LARC. The results of this study support the need to look for al...

Humans Male Middle Aged Aged Female +7 autres

Intraparenchymal metastases as a cause for local recurrence of pancreatic cancer.

Feb 2023

DOI: 10.1111/his.14839 PMID: 36371607

Using CODA, a technique for three-dimensional reconstruction of large tissues, Kiemen et al. report observation of a microscopic focus of pancreatic cancer found in the vasculature of grossly normal h...

Humans Pancreatic Neoplasms Pancreas Neoplasm Recurrence, Local Pancreatic Neoplasms

Does the Addition of Mutations of CTNNB1 S45F to Clinical Factors Allow Prediction of Local Recurrence in Patients With a Desmoid Tumor? A Local Recurrence Risk Model.

01 10 2023

DOI: 10.1097/CORR.0000000000002627 PMID: 37104792

The initial approach to the treatment of desmoid tumors has changed from surgical resection to watchful waiting. However, surgery is still sometimes considered for some patients, and it is likely that... We sought to explore whether a combined molecular and clinical prognostic model for relapse in patients with desmoid tumors treated with surgery would allow us to identify patients who might do well w... This was a retrospective, single-center study of 107 patients with desmoid tumors who were surgically treated between January 1980 and December 2015, with a median follow-up of 106 months (range 7 to ... The multivariable analysis showed that S45F mutations (hazard ratio 5.25 [95% confidence interval 2.27 to 12.15]; p < 0.001) and tumor in the extremities (HR 3.15 [95% CI 1.35 to 7.33]; p = 0.008) wer... CTNNB1 S45F mutations combined with other clinical variables are a potential prognostic biomarker associated with the risk of relapse in patients with desmoid tumors. The developed nomogram is simple ... Level III, therapeutic study....

Humans Fibromatosis, Aggressive Retrospective Studies Neoplasm Recurrence, Local Mutation +2 autres

Risk Factors of Second Local Recurrence in Surgically Treated Recurrent Brain Metastases: An Exploratory Analysis.

Nov 2022

DOI: 10.1016/j.wneu.2022.08.066 PMID: 36028114

A first local recurrence is common after resection or radiotherapy for brain metastasis (BM). However, patients with BMs can develop multiple local recurrences over time. Published data on second loca... Patients were identified from a database at Brigham and Women's Hospital in Boston. Hazard ratios and 95% confidence intervals for predictors of a second local recurrence were computed using a Cox pro... Of 170 identified surgically treated first locally recurrent lesions, 74 (43.5%) progressed to second locally recurrent lesions at a median of 7 months after craniotomy. Subtotal resection of the firs... A second local recurrence occurred after 43.5% of craniotomies for first recurrent lesions. Subtotal resection and infratentorial location were the strongest risk factors for worse second local recurr...

Humans Female Neoplasm Recurrence, Local Prognosis Risk Factors +3 autres

Applying a neoscore in locally advanced rectal cancer is beneficial in predicting local recurrences after surgery.

2023

DOI: 10.1371/journal.pone.0285709 PMID: 37172066

The current study was undertaken to provide more detailed prognostic models for early prediction of local recurrences and local recurrence free survival (RFS) using different radiologic and pathologic... One hundred patients with locally advanced rectal carcinomas decided to receive neoadjuvant CRT were retrospectively recruited, Hazard ratios (HR) were determined in the two cox regression models and ... HR of 1st group of models: T+N, T+N+G, T+N+G+S, T+N+G+S+PNI, and T+N+G+S+PNI+R were summated and categorized into scores, these scores were significantly correlated with the risk of recurrence (Somer'... We propose that the addition of biologic factors to staging of rectal cancer provide precise stratification and association with local recurrences in patients received preoperative CRT....

Humans Retrospective Studies Prognosis Rectum Rectal Neoplasms +6 autres

Surgery of resectable local recurrence following colorectal cancer: Compartmental surgery improves local control.

Nov 2022

DOI: 10.1002/jso.26990 PMID: 35779039

This study aims to identify prognostic factors and define the best extent of surgery for optimizing treatment of local recurrence (LR) following colorectal cancer (CRC).... An institutional database of consecutive patients who underwent radical resection (R0/R1) of LR following CRC was analyzed prospectively from 2010 to 2021 at one tertiary cancer center.... In this study, 75 patients were included with LR following CRC and analyzed. Patients were categorized as compartmental resections (CompRe) (n = 47) if all adjacent organs were systematically removed,... Complete compartmental surgery is safe and improves local control. Optimal LR resection needs to remove all contiguous organs, with or without tumor involvement....

Colorectal Neoplasms Digestive System Surgical Procedures Humans Neoplasm Recurrence, Local Prognosis +3 autres

Recurrent RET fusions in fibrosarcoma-like neoplasms in adult viscera: expanding the clinicopathological and genetic spectrum.

Mar 2023

DOI: 10.1111/his.14847 PMID: 36443894

RET-fused mesenchymal neoplasms mostly affect the soft tissue of paediatric patients. Given their responsiveness to selective RET inhibitors, it remains critical to identify those extraordinary cases ... Clinicopathological features were assessed and partner agnostic targeted next-generation sequencing on clinically validated platforms were performed. The patients were 18, 53, and 55 years old and inc... Our study expands the clinicopathological and genetic spectrum of mesenchymal neoplasms associated with RET fusions....

Female Humans Male Adult Child +7 autres

Xanthènes : Questions médicales fréquentes

Termes MeSH sélectionnés :

Questions fréquentes et termes MeSH associés

Diagnostic 5

Symptômes 5

Prévention 5

Traitements 5

Complications 5

Facteurs de risque 5

Contenu validé par Dr Olivier Menir

Sous-catégories

Propanthéline

Pyronine

Rhodamines

Thioxanthènes

Xanthones

Rhodamine 123

Chlorprothixène

Clopenthixol

Flupentixol

Hycanthone

Tiotixène

Lucanthone

Auteurs principaux

Sources (10000 au total)