questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Protéines du sang
Immunoprotéines
Protéines du système du complément
Complément C3
Complément C3b
Complément C3c
Complément C3c : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Compléments
Tests de laboratoire
Compléments
Tests de laboratoire
Maladies auto-immunes
Inflammation
Marqueurs biologiques
Pathologies
Système du complément
Diagnostic
Symptômes
5
Système immunitaire
Symptômes
Prévention
5
Prévention
Maladies chroniques
Vaccins
Système immunitaire
Stress
Système immunitaire
Examens médicaux
Prévention
Traitements
5
Immunothérapie
Traitement
Médicaments immunosuppresseurs
Compléments
Suivi médical
Compléments
Alimentation
Système immunitaire
Transfusions sanguines
Compléments
Complications
5
Infections
Maladies auto-immunes
Complications
Inflammation
Maladies cardiovasculaires
Risques
Facteurs de risque
5
Facteurs de risque
Maladies auto-immunes
Antécédents familiaux
Maladies immunitaires
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"name": "Le vaccin influence-t-il le C3c ?",
"position": 12,
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"position": 13,
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"text": "Éviter le tabagisme et une mauvaise alimentation peut aider à maintenir un C3c normal."
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"@type": "Question",
"name": "Le stress affecte-t-il le C3c ?",
"position": 14,
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"name": "Des examens réguliers sont-ils nécessaires ?",
"position": 15,
"acceptedAnswer": {
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"name": "Comment traiter un faible C3c ?",
"position": 16,
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"name": "Des médicaments affectent-ils le C3c ?",
"position": 17,
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"name": "Le C3c nécessite-t-il un suivi ?",
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"@type": "Question",
"name": "Peut-on augmenter le C3c naturellement ?",
"position": 19,
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"name": "Les transfusions affectent-elles le C3c ?",
"position": 20,
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"name": "Quelles complications peuvent survenir avec un C3c bas ?",
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"@type": "Question",
"name": "Un C3c élevé cause-t-il des complications ?",
"position": 22,
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}
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{
"@type": "Question",
"name": "Le C3c affecte-t-il la guérison des blessures ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des niveaux anormaux de C3c peuvent retarder la guérison en perturbant l'inflammation."
}
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{
"@type": "Question",
"name": "Y a-t-il des risques de thrombose liés au C3c ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des niveaux élevés de C3c peuvent être associés à un risque accru de thrombose."
}
},
{
"@type": "Question",
"name": "Le C3c influence-t-il les maladies cardiovasculaires ?",
"position": 25,
"acceptedAnswer": {
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"text": "Oui, des niveaux anormaux de C3c peuvent être liés à un risque accru de maladies cardiovasculaires."
}
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{
"@type": "Question",
"name": "Quels facteurs augmentent le risque de C3c anormal ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les maladies auto-immunes, infections chroniques et certains médicaments augmentent le risque."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il le C3c ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'âge peut affecter les niveaux de C3c, souvent en raison de changements immunitaires."
}
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{
"@type": "Question",
"name": "Le sexe joue-t-il un rôle dans le C3c ?",
"position": 28,
"acceptedAnswer": {
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"text": "Oui, des différences hormonales peuvent influencer les niveaux de C3c entre les sexes."
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"@type": "Question",
"name": "Le mode de vie affecte-t-il le C3c ?",
"position": 29,
"acceptedAnswer": {
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"text": "Oui, un mode de vie sédentaire et une mauvaise alimentation peuvent affecter le C3c."
}
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"@type": "Question",
"name": "Les antécédents familiaux influencent-ils le C3c ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des antécédents familiaux de maladies immunitaires peuvent augmenter le risque de C3c anormal."
}
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 31/03/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA. mdalakas@med.uoa.gr.
Neuroimmunology Unit, Department of Pathophysiology, Faculty of Medicine, National and Kapodistrian University of Athens, Athens, Greece. mdalakas@med.uoa.gr.
Publications dans "Complément C3c" :
4 publications dans cette catégorie
Affiliations :
Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Publications dans "Complément C3c" :
4 publications dans cette catégorie
Affiliations :
Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Publications dans "Complément C3c" :
3 publications dans cette catégorie
Affiliations :
Division of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hospital Epidemiology, Medical School Hannover, Hannover, Germany.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hospital Epidemiology, Medical School Hannover, Hannover, Germany.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hospital Epidemiology, Medical School Hannover, Hannover, Germany.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Institute for Laboratory Animal Science, Medical School Hannover, Hannover, Germany.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hospital Epidemiology, Medical School Hannover, Hannover, Germany.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hospital Epidemiology, Medical School Hannover, Hannover, Germany.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Department of Biomedicine, Aarhus University, Aarhus C, Denmark.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Translational Bio-Nanosciences Laboratory, Department of Pharmaceutical Sciences, Skaggs School of Pharmacy, University of Colorado Anschutz Medical Center, Aurora, CO, USA; Colorado Center for Nanomedicine and Nanosafety, University of Colorado Anschutz Medical Center, Aurora, CO, USA.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Radboud Institute for Molecular Life Sciences, Department of Pediatric Nephrology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Department of Immunology, University of Oslo and Oslo University Hospital Rikshospitalet, Oslo, Norway.
Linnaeus Centre for Biomaterials Chemistry, Linnaeus University, Kalmar, Sweden.
Department of Chemistry and Biomedical Sciences, Linnaeus University, Kalmar, Sweden.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
BMT Unit, Hematology Department, G. Papanicolaou Hospital, Thessaloniki, Greece.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Molecular Immunology and the Immunology Center, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD, United States.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Centre de Recherche des Cordeliers, Inserm UMR S1138, Paris, France.
Department of Nephrology Dialysis and Transplantation, University Hospital of Strasbourg, Strasbourg, France.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Centre de Recherche des Cordeliers, Inserm UMR S1138, Paris, France.
Service d'Immunologie, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
Publications dans "Complément C3c" :
The complement system is a multicomponent and multifunctional arm of the innate immune system. Complement contributes to non-specific host defence and maintains homeostasis through multifaceted proces...
The complement system is an essential component of our innate defense and plays a vital role in the pathogenesis of many diseases. Assessment of complement activation is critical in monitoring both di...
We performed a systematic analysis of the current methods used to assess complement components and reviewed whether the identified studies performed their complement measurements according to the reco...
A literature search using the Pubmed/MEDLINE database was performed focusing on studies measuring the key complement components C3, C5 and/or their split products and/or the soluble variant of the ter...
A total of 92 out of 376 studies were selected for full-text analysis. Forty-five studies (49%) were identified as using the correct sample type and techniques for their complement analyses, while 25 ...
A substantial part of the reviewed studies did not use the appropriate sample type for assessing complement activation or did not mention which sample type was used. This deviation from the standardiz...
Of the four human immunoglobulin G (IgG) subclasses, IgG4 is considered the least inflammatory, in part because it poorly activates the complement system. Regardless, in IgG4 related disease (IgG4-RD)...
Although kidney transplantation is the best treatment for end stage kidney disease, the benefits are limited by factors such as the short fall in donor numbers, the burden of immunosuppression and gra...
Complement activation is a critical feature in the development of systemic lupus erythematosus (SLE). Whether there are changes of complement components in the urine of SLE has not been reported. The ...
First, we used bioinformatics and functional enrichment to screen and identify the urine protein profile of SLE patients. Then, analyzed and verified the proteins related to the complement pathway by ...
A total of 14 complement pathway-related proteins were screened for differences in expression between the active group and the stable group, eight of these DEPs were up-regulated and six were down-reg...
Complement-related DEPs in urine have a certain correlation with SLE disease activity. Urine C9, C8A, C4B and C8G present promising non-invasive biomarkers for monitoring lupus activity....
Vaginal microbiome and the local innate immune defense, including the complement system, contribute to anti- and proinflammatory homeostasis during pregnancy and parturition. The relationship between ...
To study the association of the cervicovaginal microbiota composition to activation and regulation of the complement system during pregnancy and labor....
We recruited women during late pregnancy (weeks 41 + 5 to 42 + 0, n=48) and women in active labor (weeks 38 + 4 to 42 + 2, n=25). Mucosal swabs were taken from the external cervix and lateral fornix o...
The vaginal microbiota was...
These results indicate that bacterial composition of the vaginal microbiota could have a role in the local activation and regulation of complement-mediated inflammation during pregnancy. At the time o...
Histopathologic studies have identified immunoglobulin (Ig) deposition and complement activation as contributors of CNS tissue damage in multiple sclerosis (MS). Intrathecal IgM synthesis is associate...
CC and CAP levels were quantified in plasma and CSF of 112 patients with clinically isolated syndrome (CIS), 127 patients with MS (90 relapsing-remitting, 14 primary progressive, and 23 secondary prog...
CSF (but not plasma) levels of C3a, C4a, Ba, and Bb were increased in patients with CIS/MS, being most pronounced in those with an additional intrathecal IgM production. In CIS, doubling of C3a and C4...
CNS-compartmentalized activation of the classical and alternative pathways of complement is increased in CIS/MS and associated with the presence of an intrathecal IgM production. Increased complement ...
Several studies have shown the importance of the complement and coagulation systems in the pathogenesis of asthma....
We explored whether we could detect differentially abundant complement and coagulation proteins in the samples obtained from the small airway lining fluid by collection of exhaled particles in patient...
Exhaled particles were obtained from 20 subjects with asthma and 10 healthy controls (HC) with the PExA method and analysed with the SOMAscan proteomics platform. Lung function was assessed by nitroge...
53 proteins associated with the complement and coagulation systems were included in the analysis. Nine of those proteins were differentially abundant in subjects with asthma as compared to HC, and C3 ...
The study highlights the role of the local activation of the complement and coagulation systems in the small airway lining fluid in asthma and their association with both asthma control and small airw...
Central line associated bloodstream infections (CLABSI) with...
Malignant nephrosclerosis is a thrombotic microangiopathy associated with abnormal local activation of the complement alternative pathway (AP). However, the mechanism underlying local AP activation is...