questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Protéines du sang
Immunoprotéines
Protéines du système du complément
Complément C3
Complément C3b
Complément C3c
Complément C3c : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Compléments
Tests de laboratoire
Compléments
Tests de laboratoire
Maladies auto-immunes
Inflammation
Marqueurs biologiques
Pathologies
Système du complément
Diagnostic
Symptômes
5
Système immunitaire
Symptômes
Prévention
5
Prévention
Maladies chroniques
Vaccins
Système immunitaire
Stress
Système immunitaire
Examens médicaux
Prévention
Traitements
5
Immunothérapie
Traitement
Médicaments immunosuppresseurs
Compléments
Suivi médical
Compléments
Alimentation
Système immunitaire
Transfusions sanguines
Compléments
Complications
5
Infections
Maladies auto-immunes
Complications
Inflammation
Maladies cardiovasculaires
Risques
Facteurs de risque
5
Facteurs de risque
Maladies auto-immunes
Antécédents familiaux
Maladies immunitaires
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}
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"@type": "Question",
"name": "Le C3c affecte-t-il la guérison des blessures ?",
"position": 23,
"acceptedAnswer": {
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"text": "Des niveaux anormaux de C3c peuvent retarder la guérison en perturbant l'inflammation."
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"@type": "Question",
"name": "Y a-t-il des risques de thrombose liés au C3c ?",
"position": 24,
"acceptedAnswer": {
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"text": "Des niveaux élevés de C3c peuvent être associés à un risque accru de thrombose."
}
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"@type": "Question",
"name": "Le C3c influence-t-il les maladies cardiovasculaires ?",
"position": 25,
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}
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"@type": "Question",
"name": "Quels facteurs augmentent le risque de C3c anormal ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les maladies auto-immunes, infections chroniques et certains médicaments augmentent le risque."
}
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"@type": "Question",
"name": "L'âge influence-t-il le C3c ?",
"position": 27,
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"name": "Le sexe joue-t-il un rôle dans le C3c ?",
"position": 28,
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"name": "Le mode de vie affecte-t-il le C3c ?",
"position": 29,
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"@type": "Question",
"name": "Les antécédents familiaux influencent-ils le C3c ?",
"position": 30,
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"text": "Oui, des antécédents familiaux de maladies immunitaires peuvent augmenter le risque de C3c anormal."
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Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 31/03/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Neurology, Thomas Jefferson University, Philadelphia, PA, USA. mdalakas@med.uoa.gr.
Neuroimmunology Unit, Department of Pathophysiology, Faculty of Medicine, National and Kapodistrian University of Athens, Athens, Greece. mdalakas@med.uoa.gr.
Publications dans "Complément C3c" :
4 publications dans cette catégorie
Affiliations :
Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Publications dans "Complément C3c" :
4 publications dans cette catégorie
Affiliations :
Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Publications dans "Complément C3c" :
3 publications dans cette catégorie
Affiliations :
Division of Hematology and Medical Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, OH.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hospital Epidemiology, Medical School Hannover, Hannover, Germany.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hospital Epidemiology, Medical School Hannover, Hannover, Germany.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hospital Epidemiology, Medical School Hannover, Hannover, Germany.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Institute for Laboratory Animal Science, Medical School Hannover, Hannover, Germany.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hospital Epidemiology, Medical School Hannover, Hannover, Germany.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Institute of Medical Microbiology and Hospital Epidemiology, Medical School Hannover, Hannover, Germany.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Department of Biomedicine, Aarhus University, Aarhus C, Denmark.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Translational Bio-Nanosciences Laboratory, Department of Pharmaceutical Sciences, Skaggs School of Pharmacy, University of Colorado Anschutz Medical Center, Aurora, CO, USA; Colorado Center for Nanomedicine and Nanosafety, University of Colorado Anschutz Medical Center, Aurora, CO, USA.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Radboud Institute for Molecular Life Sciences, Department of Pediatric Nephrology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, Netherlands.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Department of Immunology, University of Oslo and Oslo University Hospital Rikshospitalet, Oslo, Norway.
Linnaeus Centre for Biomaterials Chemistry, Linnaeus University, Kalmar, Sweden.
Department of Chemistry and Biomedical Sciences, Linnaeus University, Kalmar, Sweden.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Division of Hematology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD, USA.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
BMT Unit, Hematology Department, G. Papanicolaou Hospital, Thessaloniki, Greece.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Laboratory of Molecular Immunology and the Immunology Center, National Heart, Lung, and Blood Institute (NHLBI), National Institutes of Health (NIH), Bethesda, MD, United States.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Centre de Recherche des Cordeliers, Inserm UMR S1138, Paris, France.
Department of Nephrology Dialysis and Transplantation, University Hospital of Strasbourg, Strasbourg, France.
Publications dans "Complément C3c" :
2 publications dans cette catégorie
Affiliations :
Centre de Recherche des Cordeliers, Inserm UMR S1138, Paris, France.
Service d'Immunologie, Assistance Publique-Hôpitaux de Paris, Hôpital Européen Georges Pompidou, Paris, France.
Publications dans "Complément C3c" :
To explore the impact of gender mismatch on corneal allograft rejection and rejection-related graft failure in patients with repeat penetrating keratoplasty (PK)....
A retrospective cohort was conducted at Ramathibodi Hospital, Bangkok, Thailand. Patients with repeat PK and follow-up period of at least 6 months were recruited. Demographic data, pre-operative ocula...
Of 68 patients with repeat PK, 26 patients (38.2%) were gender mismatched. There was no difference in 3-year rejection-free survival and graft survival between patients with gender mismatch and others...
Gender mismatch might not impact corneal graft rejection or rejection-related graft failure in patients with repeat PK. Younger age was found to be a strong factor associated with graft rejection. Gen...
We aimed to investigate the clinical characteristics and risk factors for graft rejection after keratoplasty in Japanese patients. We enrolled 730 cases (566 patients) of penetrating keratoplasty (PK,...
Acute rejection (AR) is a process triggered...
To report a case of epithelial downgrowth after penetrating keratoplasty....
A 58-year-old man presented with graft rejection in his three-month-old, repeat penetrating keratoplasty. Examination revealed centripetal opacification of the posterior cornea due to deep epithelizat...
Epithelial downgrowth is an uncommon complication of penetrating keratoplasty. It affects the patients' visual acuity and graft survival. Clinical observation is preferred in severe cases due to the h...
The aim of the study was to present the rates of rejection from 2018 to 2021 and evaluate the purported association between COVID-19 vaccination and corneal graft rejection....
Cases of corneal graft rejection diagnosed between January 2018 and December 2021 were reviewed. The conditional Poisson regression model of the self-controlled case series method was used to estimate...
Over the past 4 years, the annual tally of diagnosed cases of graft rejection (19 cases in year 2018, 19 cases in year 2019, 21 cases in year 2020, and 18 cases in year 2021) has remained relatively s...
No notable increase in rates of corneal graft rejection was noted in year 2021 when COVID-19 vaccination was broadly implemented. The apparent temporal relationship between COVID vaccination and corne...
To evaluate the association between donor-related factors and the risk of rejection in patients undergoing penetrating keratoplasty (PKP) for keratoconus....
A retrospective review was performed of keratoconus patients with no corneal neovascularization who underwent PKP from November 2014 to December 2016 and completed at least two years of follow-up. Pre...
A total of 201 eyes (of 201 patients) that underwent PKP for keratoconus were included. Of these, 22.9% (95% CI 17.6-29.2%) had an episode of graft rejection. The overall graft survival rate was 98.5%...
In the multivariable analysis, none of the donor-related factors were significantly associated with graft rejection; however, short death-to-surgery time may be associated with rejection after PKP. Re...
There are few predictive studies about early posttransplant outcomes taking into account baseline and posttransplant variables. The objective of this study was to create a predictive model for 30-day ...
Retrospective study with 1255 patients undergoing transplant from living and deceased donors at a tertiary health service in Brazil. Recipient, donor, transplantation, and postoperative period data we...
There were 147 (12.48%) cases of graft rejection within 30 days of transplantation. The best model was XGBoost (accuracy, 0.839; receiver operating characteristic area under the curve, 0.715; precisio...
We fitted a machine learning model to predict 30-day graft rejection after kidney transplantation that reaches a higher accuracy and precision. Machine learning models could contribute to predicting k...
Microvasculature consisting of endothelial cells and pericytes is the main site of injury during antibody-mediated rejection (ABMR) of renal grafts. Little is known about the mechanisms of activation ...
Rejection is one of the major factors affecting the long-term prognosis of kidney transplantation, and timely recognition and aggressive treatment of rejection is essential to prevent disease progress...
The complement system, consisting of more than thirty different soluble and cell-bound proteins, exerts essential functions both in the innate and adaptive immune systems and is believed to be an impo...
In this case-control feasibility study, complement factors C3a, C3dg, C4a, and C5a were measured in plasma and C3dg and sC5b-9 associated C9 neoantigen in urine in 15 kidney transplant recipients with...
In plasma, there were no significant differences between the rejection and the control group. However, steroids and pretransplant C3dg levels significantly influenced C3dg. Within the rejection group,...
This study shows increased plasma C3a and C3dg in kidney transplant recipients, primarily with T cell mediated rejection. This finding suggests that consecutive measurements of C3a and C3dg in plasma ...