questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Protéines membranaires
Récepteurs de surface cellulaire
Récepteurs immunologiques
Intégrines
Intégrines : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic and Statistical Manual of Mental Disorders
Diagnostic
5
Intégrines
Tests génétiques
Cytométrie en flux
Immunofluorescence
Imagerie moléculaire
Intégrines
Marqueurs tumoraux
Intégrines
Symptômes
5
Troubles de la coagulation
Intégrines
Cicatrisation
Migration cellulaire
Douleur articulaire
Arthrite
Maladies cutanées
Épidermolyse bulleuse
Prévention
5
Prévention
Mode de vie sain
Vaccination
Réponse immunitaire
Exercice physique
Santé cellulaire
Alimentation
Antioxydants
Traitements
5
Thérapies biologiques
Maladies auto-immunes
Médicaments anti-inflammatoires
Intégrines
Thérapie génique
Intégrines
Greffes d'organes
Rejet de greffe
Complications
5
Infections
Maladies auto-immunes
Maladies cardiovasculaires
Athérosclérose
Complications cutanées
Épidermolyse
Troubles neurologiques
Intégrines
Facteurs de risque
5
Facteurs de risque
Maladies auto-immunes
Vieillissement
Intégrines
Tabagisme
Santé cellulaire
Stress oxydatif
Intégrines
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{
"@type": "Question",
"name": "Les biopsies sont-elles utiles pour les intégrines ?",
"position": 3,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les biopsies peuvent révéler des anomalies d'expression des intégrines dans les tissus."
}
},
{
"@type": "Question",
"name": "Peut-on détecter les intégrines par imagerie ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines techniques d'imagerie moléculaire peuvent visualiser l'expression des intégrines."
}
},
{
"@type": "Question",
"name": "Quels marqueurs sont associés aux intégrines ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des marqueurs comme CD29 et CD49 peuvent être utilisés pour identifier les intégrines."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent une anomalie des intégrines ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des problèmes d'adhésion cellulaire peuvent entraîner des inflammations et des infections récurrentes."
}
},
{
"@type": "Question",
"name": "Les troubles de la coagulation sont-ils liés aux intégrines ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies des intégrines peuvent provoquer des troubles de la coagulation sanguine."
}
},
{
"@type": "Question",
"name": "Comment les intégrines affectent-elles la cicatrisation ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les intégrines sont essentielles pour la migration cellulaire et la formation de nouveaux tissus lors de la cicatrisation."
}
},
{
"@type": "Question",
"name": "Les douleurs articulaires peuvent-elles être liées aux intégrines ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des dysfonctionnements des intégrines peuvent contribuer à des douleurs articulaires et à l'arthrite."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes cutanés associés aux intégrines ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des anomalies des intégrines peuvent entraîner des maladies cutanées comme l'épidermolyse bulleuse."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les troubles liés aux intégrines ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à prévenir certains troubles liés aux intégrines."
}
},
{
"@type": "Question",
"name": "Les vaccinations influencent-elles les intégrines ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines vaccinations peuvent moduler l'expression des intégrines, influençant la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "L'exercice physique affecte-t-il les intégrines ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut améliorer la fonction des intégrines et la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Le stress a-t-il un impact sur les intégrines ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress chronique peut altérer l'expression des intégrines, affectant la santé immunitaire."
}
},
{
"@type": "Question",
"name": "Les habitudes alimentaires influencent-elles les intégrines ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en antioxydants peut soutenir la fonction des intégrines et la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent les intégrines ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies biologiques, comme les inhibiteurs d'intégrines, sont utilisées pour traiter certaines maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Les médicaments anti-inflammatoires aident-ils les intégrines ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les anti-inflammatoires peuvent réduire l'inflammation liée aux dysfonctionnements des intégrines."
}
},
{
"@type": "Question",
"name": "La thérapie génique peut-elle corriger les anomalies des intégrines ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique est une approche prometteuse pour corriger certaines anomalies des intégrines."
}
},
{
"@type": "Question",
"name": "Les greffes d'organes sont-elles affectées par les intégrines ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les intégrines jouent un rôle clé dans l'acceptation ou le rejet des greffes d'organes."
}
},
{
"@type": "Question",
"name": "Comment les intégrines sont-elles ciblées dans le cancer ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des traitements ciblant les intégrines peuvent inhiber la métastase et la progression tumorale."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec des anomalies des intégrines ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des infections récurrentes, des troubles de la coagulation et des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Les anomalies des intégrines peuvent-elles causer des cancers ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies dans l'expression des intégrines sont associées à une augmentation du risque de cancer."
}
},
{
"@type": "Question",
"name": "Comment les intégrines affectent-elles la santé cardiovasculaire ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des dysfonctionnements des intégrines peuvent contribuer à des maladies cardiovasculaires et à l'athérosclérose."
}
},
{
"@type": "Question",
"name": "Les complications cutanées sont-elles fréquentes avec les intégrines ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies des intégrines peuvent entraîner des maladies cutanées graves comme l'épidermolyse."
}
},
{
"@type": "Question",
"name": "Les troubles neurologiques peuvent-ils être liés aux intégrines ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines études suggèrent un lien entre les anomalies des intégrines et des troubles neurologiques."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque de troubles des intégrines ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des facteurs génétiques, des infections chroniques et des maladies auto-immunes augmentent le risque."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il la fonction des intégrines ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le vieillissement peut altérer l'expression et la fonction des intégrines dans le corps."
}
},
{
"@type": "Question",
"name": "Le tabagisme affecte-t-il les intégrines ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme peut perturber l'expression des intégrines et affecter la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Le diabète influence-t-il les intégrines ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le diabète peut altérer la fonction des intégrines, augmentant le risque de complications."
}
},
{
"@type": "Question",
"name": "Le stress oxydatif affecte-t-il les intégrines ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress oxydatif peut endommager les intégrines et perturber leur fonction normale."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 03/02/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Turku Bioscience Center, University of Turku and Åbo Akademi University, FIN-20520 Turku, Finland; Department of Biochemistry, University of Turku, FIN-20520 Turku, Finland. Electronic address: joivaska@utu.fi.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Shenzhen Jiake Biotechnology, Shenzhen, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Cell Physiology and Metabolism, University of Geneva, Centre Médical Universitaire, Rue Michel-Servet 1, 1211 Geneva 4, Switzerland.
Zoological Institute, Cell- and Neurobiology, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, FI-33520 Tampere, Finland.
Fimlab Laboratories, Biokatu 4, FI-33520 Tampere, Finland.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Cell Physiology and Metabolism, University of Geneva, Centre Médical Universitaire, Rue Michel-Servet 1, 1211 Geneva 4, Switzerland bernhard.wehrle-haller@unige.ch.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Nuclear Medicine & Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Nuclear Medicine & Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Zhong Yuan Academy of Biological Medicine, Liaocheng People's Hospital, No. 67 Dongchang West Road, Liaocheng 252000, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Orthopedics, Suzhou Ninth People's Hospital, Soochow University, Suzhou, Jiangsu, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China. yzeng@sibcb.ac.cn.
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China. yzeng@sibcb.ac.cn.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China. jfchen@sibcb.ac.cn.
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China. jfchen@sibcb.ac.cn.
Publications dans "Intégrines" :
The purpose of this study was to validate the Diagnostic and Statistical Manual of Mental Disorders-5 (DSM-5) Cross-Cutting Symptom Measure (CCSM) as a screening tool for a wide variety of disorders w...
Participants (N = 851) were referred for coordinated specialty care services (mean age = 20.26 years (SD = 2.97); 82.5 % Caucasian, 7.5 % African American, 0.7 % Native American, 0.7 % Pacific Islande...
At optimal cut-score, specificity ranged from 57 to 77 % for depression, anxiety, substance use and psychosis domains; sensitivity ranged from 63 to 72 %. Scores for depression, anxiety, substance use...
Criterion measures did not have inter-rater reliabilities as this is generally prohibitive in clinic settings....
The CCSM could provide a first step in screening for multiple disorders; however, it cannot replace structured interviews for making diagnoses related to these conditions....
The alternative model for personality disorder (AMPD) is currently included in Section III of the Diagnostic and Statistical Manual for Mental Disorders, Fifth Edition (DSM-5). This review sought to s...
Screen use is part of daily life worldwide and morbidity related to excess use of screens has been reported. Some use of screens in excess could indicate a screen use disorder (ScUD). An integrative a...
Our goals were (1) to describe screen uses in a general population sample and (2) to test the unidimensionality, local independence, and psychometric properties of the 9 Diagnostic and Statistical Man...
This cross-sectional survey in a French suburban city targeted adults and adolescents. A self-administered questionnaire covered the main types of screens used and their use for various activities in ...
Among the 300 participants, 171 (57.0%) were female (mean age 27 years), 297 (99.0%) used screens, 134 (44.7%) reported at least one criterion (potential problem users), and 5 (1.7%) reported 5 or mor...
We described screen uses in a French community sample and have shown that the adaptation of the DSM-5 IGD to "ScUD" has good psychometric validity and is discriminating, confirming our hypothesis. We ...
The fifth edition of the American Psychiatric Association's (APA)...
This study evaluated the consistency between the International Classification of Diseases, 11th Edition (ICD-11) for gaming disorder (ICD-11-GD) and Diagnostic and Statistical Manual of Mental Disorde...
We recruited 60 participants with GD, 45 participants who engaged in hazardous gaming (HG), and 120 controls based on a diagnostic interview. Their operationalization of functional impairment and stag...
We observed satisfactory consistency (kappa value = 0.80) with a diagnostic accuracy of 91.5% between the ICD-11-GD and DSM-5-IGD criteria. Furthermore, 16 participants with IGD in DSM-5 were determin...
There is a good consistency between ICD-11-GD and DSM-5-IGD criteria. The ICD-11 criteria have a high threshold for diagnosing GD. HG criteria could compensate for this high threshold and identify ind...
The conceptual basis of psychopathology within cancer survivorship is critical, as the chosen conceptualisation informs assessment and explanatory models, as well as interventions and supportive care ...
Age-related psychometric differences in Diagnostic and Statistical Manual of Mental Disorders, 5th Edition (DSM-5) opioid use disorder (OUD) diagnostic criteria have been hypothesized, but not been te...
People who participated in the 2012-2013 National Epidemiologic Survey on Alcohol and Related Conditions III and reported past 12-month nonmedical use of prescription opioids were included. YAs were 1...
One in 5 people met the DSM-5 OUD diagnostic criteria for OUD within the past 12 months, with the most endorsed criteria being tolerance (17.96%). DIF was identified for 3 criteria, including (1) taki...
These findings suggest that there may be age-related variations in the DSM-5 OUD diagnostic criteria's ability to detect latent OUD. Future research should identify contributing factors and the influe...
There is a scarcity of summarizing data on the epidemiology of insomnia in older persons, especially when diagnosed with international criteria. This study aimed to estimate the prevalence and correla...
Through PubMed/MEDLINE, EMBASE, and Web of Science (WoS), we searched for relevant articles published before June 28, 2023. The risk of bias was weighed using the Joanna Briggs Institute's (JBI's) cri...
We included 18,270 participants across 16 studies. The male/female ratio was 0.89 (12 studies), and the mean age varied from 65.9 to 83.1 years (8 studies). The pooled prevalence of insomnia was 19.6%...
Nearly one in every five old individuals was considered to have insomnia disorder, which was associated with the gender and the existence of mental health and/or somatic conditions....
We registered the protocol in the International Prospective Register of Systematic Reviews (PROSPERO) with registration number: CRD42022344675....
The alternative model of personality disorders (AMPD) traits were designed to maintain continuity with the Section II personality disorder (PD) diagnoses by retaining the same clinical information. Wh...
The Impact of Event Scale-Revised (IES-R) is a widely used self-report for assessing posttraumatic stress disorder (PTSD), originally aligned with Diagnostic and Statistical Manual of Mental Disorders...
A total of 238 participants recruited from multiple psychiatric centers, including 67 patients with PTSD, 72 patients with psychiatric controls, and 99 healthy controls, were included in the study. Al...
The IES-R demonstrated good internal consistency and a high correlation with the PCL-5. Through factor analysis, 5 distinct dimensions emerged within the IES-R: sleep disturbance, intrusion, hyperarou...
These findings underscore the scale's concurrent validity with the DSM-5 PTSD criteria and its effectiveness as a screening tool. Implementing a cutoff score of 25 on the IES-R can enhance its utility...