questionsmedicales.fr
Acides aminés, peptides et protéines
Protéines
Protéines membranaires
Récepteurs de surface cellulaire
Récepteurs immunologiques
Intégrines
Intégrines : Questions médicales fréquentes
Termes MeSH sélectionnés :
Predictive Value of Tests
Diagnostic
5
Intégrines
Tests génétiques
Cytométrie en flux
Immunofluorescence
Imagerie moléculaire
Intégrines
Marqueurs tumoraux
Intégrines
Symptômes
5
Troubles de la coagulation
Intégrines
Cicatrisation
Migration cellulaire
Douleur articulaire
Arthrite
Maladies cutanées
Épidermolyse bulleuse
Prévention
5
Prévention
Mode de vie sain
Vaccination
Réponse immunitaire
Exercice physique
Santé cellulaire
Alimentation
Antioxydants
Traitements
5
Thérapies biologiques
Maladies auto-immunes
Médicaments anti-inflammatoires
Intégrines
Thérapie génique
Intégrines
Greffes d'organes
Rejet de greffe
Complications
5
Infections
Maladies auto-immunes
Maladies cardiovasculaires
Athérosclérose
Complications cutanées
Épidermolyse
Troubles neurologiques
Intégrines
Facteurs de risque
5
Facteurs de risque
Maladies auto-immunes
Vieillissement
Intégrines
Tabagisme
Santé cellulaire
Stress oxydatif
Intégrines
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{
"@type": "Question",
"name": "Peut-on détecter les intégrines par imagerie ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines techniques d'imagerie moléculaire peuvent visualiser l'expression des intégrines."
}
},
{
"@type": "Question",
"name": "Quels marqueurs sont associés aux intégrines ?",
"position": 5,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des marqueurs comme CD29 et CD49 peuvent être utilisés pour identifier les intégrines."
}
},
{
"@type": "Question",
"name": "Quels symptômes indiquent une anomalie des intégrines ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des problèmes d'adhésion cellulaire peuvent entraîner des inflammations et des infections récurrentes."
}
},
{
"@type": "Question",
"name": "Les troubles de la coagulation sont-ils liés aux intégrines ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies des intégrines peuvent provoquer des troubles de la coagulation sanguine."
}
},
{
"@type": "Question",
"name": "Comment les intégrines affectent-elles la cicatrisation ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les intégrines sont essentielles pour la migration cellulaire et la formation de nouveaux tissus lors de la cicatrisation."
}
},
{
"@type": "Question",
"name": "Les douleurs articulaires peuvent-elles être liées aux intégrines ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des dysfonctionnements des intégrines peuvent contribuer à des douleurs articulaires et à l'arthrite."
}
},
{
"@type": "Question",
"name": "Y a-t-il des symptômes cutanés associés aux intégrines ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des anomalies des intégrines peuvent entraîner des maladies cutanées comme l'épidermolyse bulleuse."
}
},
{
"@type": "Question",
"name": "Peut-on prévenir les troubles liés aux intégrines ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation équilibrée et un mode de vie sain peuvent aider à prévenir certains troubles liés aux intégrines."
}
},
{
"@type": "Question",
"name": "Les vaccinations influencent-elles les intégrines ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines vaccinations peuvent moduler l'expression des intégrines, influençant la réponse immunitaire."
}
},
{
"@type": "Question",
"name": "L'exercice physique affecte-t-il les intégrines ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exercice régulier peut améliorer la fonction des intégrines et la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Le stress a-t-il un impact sur les intégrines ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le stress chronique peut altérer l'expression des intégrines, affectant la santé immunitaire."
}
},
{
"@type": "Question",
"name": "Les habitudes alimentaires influencent-elles les intégrines ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Une alimentation riche en antioxydants peut soutenir la fonction des intégrines et la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent les intégrines ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des thérapies biologiques, comme les inhibiteurs d'intégrines, sont utilisées pour traiter certaines maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Les médicaments anti-inflammatoires aident-ils les intégrines ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les anti-inflammatoires peuvent réduire l'inflammation liée aux dysfonctionnements des intégrines."
}
},
{
"@type": "Question",
"name": "La thérapie génique peut-elle corriger les anomalies des intégrines ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La thérapie génique est une approche prometteuse pour corriger certaines anomalies des intégrines."
}
},
{
"@type": "Question",
"name": "Les greffes d'organes sont-elles affectées par les intégrines ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les intégrines jouent un rôle clé dans l'acceptation ou le rejet des greffes d'organes."
}
},
{
"@type": "Question",
"name": "Comment les intégrines sont-elles ciblées dans le cancer ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des traitements ciblant les intégrines peuvent inhiber la métastase et la progression tumorale."
}
},
{
"@type": "Question",
"name": "Quelles complications peuvent survenir avec des anomalies des intégrines ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des complications incluent des infections récurrentes, des troubles de la coagulation et des maladies auto-immunes."
}
},
{
"@type": "Question",
"name": "Les anomalies des intégrines peuvent-elles causer des cancers ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies dans l'expression des intégrines sont associées à une augmentation du risque de cancer."
}
},
{
"@type": "Question",
"name": "Comment les intégrines affectent-elles la santé cardiovasculaire ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des dysfonctionnements des intégrines peuvent contribuer à des maladies cardiovasculaires et à l'athérosclérose."
}
},
{
"@type": "Question",
"name": "Les complications cutanées sont-elles fréquentes avec les intégrines ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des anomalies des intégrines peuvent entraîner des maladies cutanées graves comme l'épidermolyse."
}
},
{
"@type": "Question",
"name": "Les troubles neurologiques peuvent-ils être liés aux intégrines ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines études suggèrent un lien entre les anomalies des intégrines et des troubles neurologiques."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent le risque de troubles des intégrines ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des facteurs génétiques, des infections chroniques et des maladies auto-immunes augmentent le risque."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il la fonction des intégrines ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le vieillissement peut altérer l'expression et la fonction des intégrines dans le corps."
}
},
{
"@type": "Question",
"name": "Le tabagisme affecte-t-il les intégrines ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le tabagisme peut perturber l'expression des intégrines et affecter la santé cellulaire."
}
},
{
"@type": "Question",
"name": "Le diabète influence-t-il les intégrines ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le diabète peut altérer la fonction des intégrines, augmentant le risque de complications."
}
},
{
"@type": "Question",
"name": "Le stress oxydatif affecte-t-il les intégrines ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress oxydatif peut endommager les intégrines et perturber leur fonction normale."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 04/05/2025
Contenu vérifié selon les dernières recommandations médicales
3 publications dans cette catégorie
Affiliations :
Turku Bioscience Center, University of Turku and Åbo Akademi University, FIN-20520 Turku, Finland; Department of Biochemistry, University of Turku, FIN-20520 Turku, Finland. Electronic address: joivaska@utu.fi.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Shenzhen Jiake Biotechnology, Shenzhen, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Cell Physiology and Metabolism, University of Geneva, Centre Médical Universitaire, Rue Michel-Servet 1, 1211 Geneva 4, Switzerland.
Zoological Institute, Cell- and Neurobiology, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Faculty of Medicine and Health Technology, Tampere University, Arvo Ylpön katu 34, FI-33520 Tampere, Finland.
Fimlab Laboratories, Biokatu 4, FI-33520 Tampere, Finland.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Cell Physiology and Metabolism, University of Geneva, Centre Médical Universitaire, Rue Michel-Servet 1, 1211 Geneva 4, Switzerland bernhard.wehrle-haller@unige.ch.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Nuclear Medicine & Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Nuclear Medicine & Minnan PET Center, Xiamen Cancer Hospital, The First Affiliated Hospital of Xiamen University, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Molecular Vaccinology and Molecular Diagnostics & Center for Molecular Imaging and Translational Medicine, School of Public Health, Xiamen University, Xiamen, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Zhong Yuan Academy of Biological Medicine, Liaocheng People's Hospital, No. 67 Dongchang West Road, Liaocheng 252000, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Vascular Surgery, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Hubei Key Laboratory of Biological Targeted Therapy, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
Department of Orthopedics, Suzhou Ninth People's Hospital, Soochow University, Suzhou, Jiangsu, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China.
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China. yzeng@sibcb.ac.cn.
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China. yzeng@sibcb.ac.cn.
Publications dans "Intégrines" :
2 publications dans cette catégorie
Affiliations :
School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, Hangzhou, Zhejiang, China. jfchen@sibcb.ac.cn.
State Key Laboratory of Cell Biology, Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai, China. jfchen@sibcb.ac.cn.
Publications dans "Intégrines" :
Positive and negative predictive values are important measures of the clinical accuracy of a diagnostic test. Various test statistics have been proposed to compare positive predictive values or negati...
Early and intermediate serological screening cannot detect sex chromosome abnormalities. Currently, noninvasive prenatal testing (NIPT) is the only procedure available for screening such disorders; ho...
A total of 47,855 pregnant women underwent NIPT at our referral center from January 2014 to December 2020. Of the 314 patients with a positive NIPT indicating sex chromosome abnormalities, 260 were sc...
Improvements in detection and analytical technologies are needed to increase the accuracy of sex chromosome abnormalities detection. Pregnant women with a positive NIPT for these abnormalities may req...
Positive and negative predictive values of a diagnostic test are two important measures of test accuracy, which are more relevant in clinical settings than sensitivity and specificity. Statistical met...
Multitarget stool DNA (mt-sDNA) testing is a stool-based screening test for colorectal cancer (CRC). In a single instance of testing, the pivotal Food and Drug Administration-approval study (NCT013977...
Colonoscopy and pathology reports were reviewed retrospectively for patients with a negative mt-sDNA on the first round of screening and a positive mt-sDNA on the second round. The test-positivity rat...
A total of 2758 patients completed a second test at a median of 3.2 years after the first test. Of these, 422 (15%) had a positive second mt-sDNA. The PPV was 0.25% for CRC, 24% for APL, and 67% for a...
mt-sDNA test positive rate and PPV were similar between the first and second rounds of screening. These observations confirm the utility of a second round of mt-sDNA screening and may inform estimates...
Molecular testing helps stratify risk of malignancy in indeterminate thyroid nodules, but it may be limited in its ability to rule out malignancy in large nodules....
We compared small thyroid nodules (<4 cm) to large thyroid nodules (4 cm or greater) in a retrospective, single center, cohort study of indeterminate thyroid nodules analyzed with ThyroSeq from 10/201...
A total of 204 thyroid nodules were analyzed with ThyroSeq and 62 underwent resection allowing comparison to final pathology for 48 small nodules and 14 large nodules. A greater proportion of large no...
Large thyroid nodules are associated with a higher rate of false negative results and a lower negative predictive value during molecular analysis of indeterminate thyroid nodules....
Previous studies have not described separate positive predictive values for Ortolani and Barlow tests in clinical hip screening. We aimed to determine the positive predictive values at discharge follo...
We included all infants with suspected or diagnosed DDH at the study hospital from 2015 to 2017 in this retrospective study. Infants with positive Ortolani or Barlow test after birth were referred for...
There were 33 Ortolani-positive hips and 103 Barlow-positive hips in 105 referred infants (30% male) at the screening. They received ultrasound examination at mean 21.7 days of age (SD 4.8, range 11-3...
The Ortolani test, performed by a specialist at the maternity ward, has a high positive predictive value for developmental dysplasia of the hip....
In patients with suspected pulmonary embolism (PE), the number of unnecessary computed tomography pulmonary angiography (CTPA) scans remains high, especially in patients with low pre-test probability ...
Background Administrative data permit analysis of large cohorts but rely on...
To establish the positive predictive values (PPV) of cfDNA testing based on data from a nationwide survey of independent clinical cytogenetics laboratories....
Prenatal diagnostic test results obtained by Italian laboratories between 2013 and March 2020 were compiled for women with positive non-invasive prenatal tests (NIPT), without an NIPT result, and case...
Diagnostic test results were collected for 1327 women with a positive NIPT. The highest PPVs were for Trisomy (T) 21 (624/671, 93%) and XYY (26/27, 96.3%), while rare autosomal trisomies (9/47, 19.1%)...
NIPT PPVs differ across the conditions screened and the tissues studied in diagnostic testing. This variability, issues associated with fetal sex discordancy, and no results, illustrate the importance...
In Korea, we conducted a national observational study to calculate the positive predictive value of SARS-CoV-2 rapid antigen tests in K-12 schools during the Omicron variant surge in March 2022. The w...