questionsmedicales.fr
Facteurs biologiques
Protéines et peptides de signalisation intercellulaire
Cytokines
Chimiokines
Chimiokines CC
Protéines chimioattractives monocytaires
Chimiokine CCL2
Chimiokine CCL2 : Questions médicales fréquentes
Termes MeSH sélectionnés :
Single-Cell Gene Expression Analysis
Diagnostic
5
Chimiokines
CCL2
Tests de laboratoire
Inflammation
CCL2
Protéines C-réactives
Biomarqueurs
Maladies auto-immunes
CCL2
Maladies cardiovasculaires
Inflammation
CCL2
Liquide céphalorachidien
Inflammation
CCL2
Symptômes
5
Symptômes
Inflammation
CCL2
Sclérose en plaques
Symptômes neurologiques
CCL2
Système immunitaire
Monocytes
CCL2
Douleur
Inflammation
CCL2
Prévention
5
Mode de vie sain
CCL2
Prévention
Alimentation
Antioxydants
CCL2
Sommeil
Inflammation
CCL2
Traitements
5
Inhibiteurs
Maladies inflammatoires
CCL2
Thérapies anticancéreuses
CCL2
Inflammation
Anti-inflammatoires
CCL2
Inflammation
Plantes médicinales
CCL2
Traitements naturels
Corticostéroïdes
CCL2
Inflammation
Complications
5
Complications
Maladies cardiovasculaires
CCL2
Maladies neurodégénératives
Alzheimer
CCL2
Diabète
Inflammation
CCL2
Infections
Inflammation
CCL2
Troubles auto-immuns
Polyarthrite
CCL2
Facteurs de risque
5
Infections chroniques
CCL2
Inflammation
Régime alimentaire
Graisses saturées
CCL2
Manque d'exercice
Inflammation
CCL2
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"name": "Quels symptômes sont associés à des niveaux élevés de CCL2 ?",
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"@type": "Question",
"name": "CCL2 est-il lié à des symptômes neurologiques ?",
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{
"@type": "Question",
"name": "Comment CCL2 affecte-t-il le système immunitaire ?",
"position": 8,
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{
"@type": "Question",
"name": "Des niveaux de CCL2 peuvent-ils causer de la douleur ?",
"position": 9,
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"name": "CCL2 est-il impliqué dans des maladies respiratoires ?",
"position": 10,
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{
"@type": "Question",
"name": "Comment réduire les niveaux de CCL2 ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Adopter un mode de vie sain, avec une alimentation équilibrée et de l'exercice, peut aider."
}
},
{
"@type": "Question",
"name": "Le stress influence-t-il CCL2 ?",
"position": 12,
"acceptedAnswer": {
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"text": "Oui, le stress chronique peut augmenter les niveaux de CCL2 et l'inflammation."
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{
"@type": "Question",
"name": "Y a-t-il des aliments qui réduisent CCL2 ?",
"position": 13,
"acceptedAnswer": {
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"text": "Des aliments riches en antioxydants, comme les baies, peuvent aider à réduire CCL2."
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{
"@type": "Question",
"name": "L'exercice physique affecte-t-il CCL2 ?",
"position": 14,
"acceptedAnswer": {
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"text": "Oui, l'exercice régulier peut diminuer les niveaux de CCL2 et améliorer la santé globale."
}
},
{
"@type": "Question",
"name": "La qualité du sommeil influence-t-elle CCL2 ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un sommeil de qualité peut réduire l'inflammation et les niveaux de CCL2 dans le corps."
}
},
{
"@type": "Question",
"name": "Quels traitements ciblent CCL2 ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des inhibiteurs de CCL2 sont en développement pour traiter des maladies inflammatoires."
}
},
{
"@type": "Question",
"name": "CCL2 peut-il être une cible pour des thérapies anticancéreuses ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, cibler CCL2 pourrait aider à réduire l'infiltration tumorale et l'inflammation."
}
},
{
"@type": "Question",
"name": "Comment les anti-inflammatoires affectent-ils CCL2 ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les anti-inflammatoires peuvent réduire les niveaux de CCL2 et atténuer l'inflammation."
}
},
{
"@type": "Question",
"name": "Y a-t-il des traitements naturels pour CCL2 ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines plantes médicinales peuvent moduler les niveaux de CCL2, mais des études sont nécessaires."
}
},
{
"@type": "Question",
"name": "Les corticostéroïdes influencent-ils CCL2 ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les corticostéroïdes peuvent réduire l'expression de CCL2 dans les tissus inflammés."
}
},
{
"@type": "Question",
"name": "Quelles complications sont liées à CCL2 ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des niveaux élevés de CCL2 peuvent entraîner des complications dans les maladies cardiovasculaires."
}
},
{
"@type": "Question",
"name": "CCL2 est-il impliqué dans des maladies neurodégénératives ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, CCL2 est associé à des complications dans des maladies comme Alzheimer et Parkinson."
}
},
{
"@type": "Question",
"name": "Comment CCL2 affecte-t-il le diabète ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "CCL2 peut contribuer à l'inflammation et aux complications associées au diabète."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques d'infection liés à CCL2 ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Des niveaux élevés de CCL2 peuvent augmenter le risque d'infections en favorisant l'inflammation."
}
},
{
"@type": "Question",
"name": "CCL2 est-il lié à des troubles auto-immuns ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, CCL2 est impliqué dans des complications de troubles auto-immuns comme la polyarthrite."
}
},
{
"@type": "Question",
"name": "Quels facteurs augmentent CCL2 ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le tabagisme, l'obésité et le stress sont des facteurs de risque augmentant CCL2."
}
},
{
"@type": "Question",
"name": "L'âge influence-t-il les niveaux de CCL2 ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les niveaux de CCL2 tendent à augmenter avec l'âge, contribuant à l'inflammation."
}
},
{
"@type": "Question",
"name": "Les infections chroniques affectent-elles CCL2 ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, les infections chroniques peuvent augmenter les niveaux de CCL2 dans le corps."
}
},
{
"@type": "Question",
"name": "Le régime alimentaire influence-t-il CCL2 ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un régime riche en graisses saturées peut augmenter les niveaux de CCL2 et l'inflammation."
}
},
{
"@type": "Question",
"name": "Le manque d'exercice est-il un facteur de risque pour CCL2 ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le manque d'exercice peut contribuer à des niveaux élevés de CCL2 et à l'inflammation."
}
}
]
}
]
}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 20/02/2025
Contenu vérifié selon les dernières recommandations médicales
4 publications dans cette catégorie
Affiliations :
Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India.
Publications dans "Chimiokine CCL2" :
4 publications dans cette catégorie
Affiliations :
Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India. Electronic address: krishfbt@iitr.ac.in.
Publications dans "Chimiokine CCL2" :
3 publications dans cette catégorie
Affiliations :
Department of Biotechnology, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacology and Physiology, Faculty of Medicine and Health Sciences, Institut de pharmacologie de Sherbrooke, Université de Sherbrooke, 3001, 12e Avenue Nord, Sherbrooke, QC, Canada. elora.midavaine@usherbrooke.ca.
Centre de recherche du Centre hospitalier universitaire de Sherbrooke, CIUSSS de l'Estrie - CHUS, Sherbrooke, QC, Canada. elora.midavaine@usherbrooke.ca.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Department of Pharmacology and Physiology, Faculty of Medicine and Health Sciences, Institut de pharmacologie de Sherbrooke, Université de Sherbrooke, 3001, 12e Avenue Nord, Sherbrooke, QC, Canada.
Centre de recherche du Centre hospitalier universitaire de Sherbrooke, CIUSSS de l'Estrie - CHUS, Sherbrooke, QC, Canada.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Centre of Biomedical Research, SGPGIMS Campus, Lucknow 226014, Uttar Pradesh, India.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Department of Biosciences and Bioengineering, Indian Institute of Technology Roorkee, Roorkee 247667, Uttarakhand, India.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Sciences, University of Graz, 8010 Graz, Austria.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Institute of Pharmaceutical Sciences, University of Graz, 8010 Graz, Austria.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Department of Rehabilitation Medicine, Affiliated Hospital of Nantong University, 226001, Nantong, Jiangsu Province, China.
School of Medicine, Nantong University, 226001, Nantong, Jiangsu Province, China.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Istituti Clinici Scientifici Maugeri IRCCS, Unit of Internal Medicine and Endocrinology, Laboratory for Endocrine Disruptors, Pavia, Italy.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Istituti Clinici Scientifici Maugeri IRCCS, Unit of Internal Medicine and Endocrinology, Laboratory for Endocrine Disruptors, Pavia, Italy.
Department of Internal Medicine and Therapeutics, University of Pavia, Pavia, Italy.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, 56126 Pisa, Italy.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Department of Clinical and Experimental Medicine, University of Pisa, 56126 Pisa, Italy.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Department of Surgical, Medical and Molecular Pathology and Critical Area, University of Pisa, 56126 Pisa, Italy.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Department of Transplantation Medicine, Nephrology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland. jgozdowska@wum.edu.pl
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Department of General and Transplantation Surgery, Medical University of Warsaw, Warsaw, Poland
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
Department of Transplantation Medicine, Nephrology and Internal Medicine, Medical University of Warsaw, Warsaw, Poland
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
College of Medicine and Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Publications dans "Chimiokine CCL2" :
2 publications dans cette catégorie
Affiliations :
College of Medicine and Sharjah Institute for Medical Research, University of Sharjah, Sharjah, United Arab Emirates.
Publications dans "Chimiokine CCL2" :
Single-cell (SC) gene expression analysis is crucial to dissect the complex cellular heterogeneity of solid tumors, which is one of the main obstacles for the development of effective cancer treatment...
scMuffin provides a series of functions to calculate qualitative and quantitative scores, such as: expression of marker sets for normal and tumor conditions, pathway activity, cell state trajectories,...
The analyses offered by scMuffin and the results achieved in the case study show that our tool helps addressing the main challenges in the bioinformatics analysis of SC expression data from solid tumo...
A common feature of single-cell RNA-seq (scRNA-seq) data is that the number of cells in a cell cluster may vary widely, ranging from a few dozen to several thousand. It is not clear whether scRNA-seq ...
We addressed this question by performing scRNA-seq and poly(A)-dependent bulk RNA-seq in comparable aliquots of human induced pluripotent stem cells-derived, purified vascular endothelial and smooth m...
Findings of the current study provide a quantitative reference for designing studies that aim for identifying DEGs for specific cell clusters using scRNA-seq data and for interpreting results of such ...
There is a wealth of software that utilizes single-cell RNA-seq (scRNA-seq) data to deconvolve spatial transcriptomic spots, which currently are not yet at single-cell resolution. Here we provide prot...
Normalization is a crucial step in the analysis of single-cell RNA-sequencing (scRNA-seq) counts data. Its principal objectives are reduction of systematic biases primarily introduced through technica...
The widely adopted bulk RNA-seq measures the gene expression average of cells, masking cell type heterogeneity, which confounds downstream analyses. Therefore, identifying the cellular composition and...
We propose a new deconvolution algorithm, DSSC, which infers cell type-specific gene expression and cell type proportions of heterogeneous samples simultaneously by leveraging gene-gene and sample-sam...
DSSC provides a practical and promising alternative to the experimental techniques to characterize cellular composition and heterogeneity in the gene expression of heterogeneous samples....
Cell clustering is a prerequisite for identifying differentially expressed genes (DEGs) in single-cell RNA sequencing (scRNA-seq) data. Obtaining a perfect clustering result is of central importance f...
Here, we propose single-cell minimum enclosing ball (scMEB), a novel and fast method for detecting single-cell DEGs without prior cell clustering results. The proposed method utilizes a small part of ...
We compared scMEB to two different approaches that could be used to identify DEGs without cell clustering. The investigation of 11 real datasets revealed that scMEB outperformed rival methods in terms...
The aim of this study was to reveal the key genes associated with macrophage polarization in liver cancer....
Data were downloaded from the Gene Expression Omnibus (GEO) and the Cancer Genome Atlas databases (TCGA). R package Seurat 4.0 was used to preprocess the downloaded single-cell sequencing data, princi...
Two thousand highly variable genes were obtained after the normalization of single-cell profiles. In all, 16 principal components and 15 cell clusters were obtained. Monocytes and macrophages were the...
The key genes associated with macrophage polarization, namely CD53, TGFBI, S100A4, pyruvate kinase M, LSP1, and SPP1, may be potential therapeutic targets for liver cancer....
As an essential regulator of type I interferon (IFN) response, TMEM173 participates in immune regulation and cell death induction. In recent studies, activation of TMEM173 has been regarded as a promi...
Quantitative real-time PCR (qRT-PCR) and western blotting (WB) were applied to determine the mRNA and protein levels of TMEM173 in peripheral blood mononuclear cells (PBMCs). TMEM173 mutation status w...
The mRNA and protein levels of TMEM173 were increased in PBMCs from B-ALL patients. Besides, frameshift mutation was presented in TMEM173 sequences of 2 B-ALL patients. ScRNA-seq analysis identified t...
Our findings provide insights into the transcriptomic features of TMEM173 in the BM of high-risk B-ALL patients. Targeted activation of TMEM173 in specific cells might provide new therapeutic strategi...
The poor prognosis of sepsis warrants the investigation of biomarkers for predicting the outcome. Several studies have indicated that PANoptosis exerts a critical role in tumor initiation and developm...
We obtained Sepsis samples and scRNA-seq data from the GEO database. PANoptosis-related genes were subjected to consensus clustering and functional enrichment analysis, followed by identification of d...
Unsupervised clustering analysis using 16 PANoptosis-related genes identified three subtypes of sepsis. Kaplan-Meier analysis showed significant differences in patient survival among the subtypes, wit...
We developed a machine learning based Boruta algorithm for profiling PANoptosis related subgroups with in predicting survival and clinical features in the sepsis....
Macrophages play an important role in the occurrence and development of atherosclerosis. However, few existing studies have deliberately analyzed the changes in characteristic genes in the process of ...
Carotid atherosclerotic plaque single-cell RNA (scRNA) sequencing data were analyzed to define the cells involved and determine their transcriptomic characteristics. KEGG enrichment analysis, CIBERSOR...
Nine cell clusters were identified. M1 macrophages, M2 macrophages, and M2/M1 macrophages were identified as three clusters within the macrophages. According to pseudotime analysis, M2/M1 macrophages ...
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