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Acides nucléiques, nucléotides et nucléosides
Nucléosides
Nucléosides pyrimidiques
Désoxycytidine
Zalcitabine
Lamivudine
Lamivudine : Questions médicales fréquentes
Termes MeSH sélectionnés :
Diagnostic
5
Hépatite B
Tests de dépistage
Hépatite B
Marqueurs biologiques
Symptômes
5
Lamivudine
Effets secondaires
Lamivudine
Résistance aux médicaments
Prévention
5
Lamivudine
Résistance aux médicaments
Hépatite B
Sensibilisation
Traitements
5
Lamivudine
Administration orale
Lamivudine
Antirétroviraux
Hépatite B
Traitements antiviraux
Complications
5
Lamivudine
Résistance aux médicaments
Lamivudine
Fonction hépatique
Lamivudine
Effets à long terme
Facteurs de risque
5
Hépatite B
Facteurs de risque
Antécédents médicaux
Facteurs de risque
Statut socio-économique
Facteurs de risque
Hépatite B
Comportements à risque
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"headline": "Diagnostic sur Lamivudine",
"description": "Comment diagnostiquer une infection par le VIH ?\nQuels tests pour l'hépatite B ?\nQuels symptômes indiquent une infection par le VIH ?\nComment évaluer la charge virale du VIH ?\nQuels marqueurs pour l'hépatite B chronique ?",
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{
"@type": "Question",
"name": "Quels tests pour l'hépatite B ?",
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"@type": "Question",
"name": "Quels symptômes indiquent une infection par le VIH ?",
"position": 3,
"acceptedAnswer": {
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"text": "Symptômes comme fièvre, fatigue, éruptions cutanées, et ganglions enflés."
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{
"@type": "Question",
"name": "Comment évaluer la charge virale du VIH ?",
"position": 4,
"acceptedAnswer": {
"@type": "Answer",
"text": "Par un test sanguin mesurant la quantité d'ARN viral dans le sang."
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{
"@type": "Question",
"name": "Quels marqueurs pour l'hépatite B chronique ?",
"position": 5,
"acceptedAnswer": {
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"text": "Antigène HBs et ADN du virus de l'hépatite B dans le sang."
}
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{
"@type": "Question",
"name": "Quels sont les symptômes de l'hépatite B ?",
"position": 6,
"acceptedAnswer": {
"@type": "Answer",
"text": "Fatigue, jaunisse, douleurs abdominales, et perte d'appétit."
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},
{
"@type": "Question",
"name": "Quels effets secondaires de la lamivudine ?",
"position": 7,
"acceptedAnswer": {
"@type": "Answer",
"text": "Nausées, fatigue, maux de tête, et douleurs musculaires."
}
},
{
"@type": "Question",
"name": "Comment se manifeste une infection par le VIH ?",
"position": 8,
"acceptedAnswer": {
"@type": "Answer",
"text": "Infection aiguë avec symptômes grippaux, suivie d'une phase asymptomatique."
}
},
{
"@type": "Question",
"name": "Quels signes d'une résistance à la lamivudine ?",
"position": 9,
"acceptedAnswer": {
"@type": "Answer",
"text": "Échec du traitement, augmentation de la charge virale malgré la prise de médicaments."
}
},
{
"@type": "Question",
"name": "Quels symptômes d'une hépatite B aiguë ?",
"position": 10,
"acceptedAnswer": {
"@type": "Answer",
"text": "Symptômes similaires à ceux de la grippe, suivis de jaunisse et douleurs abdominales."
}
},
{
"@type": "Question",
"name": "Comment prévenir l'infection par le VIH ?",
"position": 11,
"acceptedAnswer": {
"@type": "Answer",
"text": "Utilisation de préservatifs, dépistage régulier et traitement préventif."
}
},
{
"@type": "Question",
"name": "Quelles mesures pour éviter l'hépatite B ?",
"position": 12,
"acceptedAnswer": {
"@type": "Answer",
"text": "Vaccination, éviter le partage d'aiguilles et pratiques sexuelles protégées."
}
},
{
"@type": "Question",
"name": "Comment réduire le risque de résistance à la lamivudine ?",
"position": 13,
"acceptedAnswer": {
"@type": "Answer",
"text": "Prendre le médicament régulièrement et suivre les recommandations médicales."
}
},
{
"@type": "Question",
"name": "Quel rôle du dépistage dans la prévention ?",
"position": 14,
"acceptedAnswer": {
"@type": "Answer",
"text": "Le dépistage précoce permet de traiter rapidement et de réduire la transmission."
}
},
{
"@type": "Question",
"name": "Comment sensibiliser à l'hépatite B ?",
"position": 15,
"acceptedAnswer": {
"@type": "Answer",
"text": "Éducation sur les modes de transmission et l'importance de la vaccination."
}
},
{
"@type": "Question",
"name": "Comment la lamivudine est-elle administrée ?",
"position": 16,
"acceptedAnswer": {
"@type": "Answer",
"text": "Par voie orale sous forme de comprimés, généralement une fois par jour."
}
},
{
"@type": "Question",
"name": "Quels autres médicaments avec la lamivudine ?",
"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Souvent combinée avec d'autres antirétroviraux pour le VIH."
}
},
{
"@type": "Question",
"name": "Quelle est la posologie de la lamivudine ?",
"position": 18,
"acceptedAnswer": {
"@type": "Answer",
"text": "La dose standard est de 150 mg deux fois par jour ou 300 mg une fois par jour."
}
},
{
"@type": "Question",
"name": "Comment surveiller l'efficacité du traitement ?",
"position": 19,
"acceptedAnswer": {
"@type": "Answer",
"text": "Par des tests réguliers de la charge virale et des tests de fonction hépatique."
}
},
{
"@type": "Question",
"name": "Quels traitements pour l'hépatite B ?",
"position": 20,
"acceptedAnswer": {
"@type": "Answer",
"text": "Antiviraux comme la lamivudine, l'entécavir ou l'interféron."
}
},
{
"@type": "Question",
"name": "Quelles complications de l'hépatite B chronique ?",
"position": 21,
"acceptedAnswer": {
"@type": "Answer",
"text": "Cirrhose, cancer du foie et insuffisance hépatique."
}
},
{
"@type": "Question",
"name": "Quels risques d'une résistance à la lamivudine ?",
"position": 22,
"acceptedAnswer": {
"@type": "Answer",
"text": "Échec du traitement et progression de l'infection par le VIH ou l'hépatite B."
}
},
{
"@type": "Question",
"name": "Comment la lamivudine affecte-t-elle le foie ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Peut entraîner des anomalies des tests hépatiques, nécessitant une surveillance."
}
},
{
"@type": "Question",
"name": "Quelles sont les complications du VIH avancé ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Infections opportunistes, cancers et défaillance multi-organes."
}
},
{
"@type": "Question",
"name": "Quels effets à long terme de la lamivudine ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Peut entraîner des effets secondaires chroniques, comme des problèmes hépatiques."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque du VIH ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Relations sexuelles non protégées, partage de seringues et antécédents d'infections."
}
},
{
"@type": "Question",
"name": "Qui est à risque d'hépatite B ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Personnes non vaccinées, utilisateurs de drogues injectables et partenaires sexuels multiples."
}
},
{
"@type": "Question",
"name": "Quel rôle des antécédents médicaux ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Antécédents d'infections ou de traitements peuvent augmenter le risque d'infection."
}
},
{
"@type": "Question",
"name": "Comment le statut socio-économique influence-t-il le risque ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Un statut socio-économique faible peut limiter l'accès aux soins et à la prévention."
}
},
{
"@type": "Question",
"name": "Quels comportements augmentent le risque d'hépatite B ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Partage d'aiguilles, relations sexuelles non protégées et manque de vaccination."
}
}
]
}
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}
Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale
Validation scientifique effectuée le 05/03/2025
Contenu vérifié selon les dernières recommandations médicales
7 publications dans cette catégorie
5 publications dans cette catégorie
Affiliations :
Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, CIBERINFEC, Spain.
HIV Unit, University Hospital 12 de Octubre-Imas12, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Infectious Diseases Unit, La Paz University Hospital, Instituto de Investigación Hospital Universitario La Paz, Madrid, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, CIBERINFEC, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
HIV Unit, University Hospital 12 de Octubre-Imas12, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Infectious Diseases Unit, La Paz University Hospital, Instituto de Investigación Hospital Universitario La Paz, Madrid, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, CIBERINFEC, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, CIBERINFEC, Spain.
HIV Unit, University Hospital 12 de Octubre-Imas12, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Infectious Diseases Unit, La Paz University Hospital, Instituto de Investigación Hospital Universitario La Paz, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
HIV Unit, University Hospital 12 de Octubre-Imas12, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
HIV Unit, University Hospital 12 de Octubre-Imas12, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Infectious Diseases Unit, La Paz University Hospital, Instituto de Investigación Hospital Universitario La Paz, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, CIBERINFEC, Spain.
HIV Unit, University Hospital 12 de Octubre-Imas12, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, CIBERINFEC, Spain.
HIV Unit, University Hospital 12 de Octubre-Imas12, Madrid, Spain.
Universidad Complutense School of Medicine, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Universidad Complutense School of Medicine, Madrid, Spain.
Department of Microbiology, University Hospital 12 de Octubre-Imas12, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Infectious Diseases Unit, La Paz University Hospital, Instituto de Investigación Hospital Universitario La Paz, Madrid, Spain.
Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, CIBERINFEC, Spain.
School of Medicine, Universidad Autónoma de Madrid, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Centro de Investigación Biomédica en Red de Enfermedades Infecciosas, CIBERINFEC, Spain.
HIV Unit, University Hospital 12 de Octubre-Imas12, Madrid, Spain.
Universidad Complutense School of Medicine, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Infectious Diseases Unit, Hospital Clínic, University of Barcelona 08036, Barcelona, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Infectious Diseases Unit, Hospital Clínic, University of Barcelona 08036, Barcelona, Spain.
CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Infectious Diseases Unit, Hospital Clínic, University of Barcelona 08036, Barcelona, Spain.
CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Infectious Diseases Unit, Hospital Clínic, University of Barcelona 08036, Barcelona, Spain.
CIBER de Enfermedades Infecciosas (CIBERINFEC), Instituto de Salud Carlos III, Madrid, Spain.
Publications dans "Lamivudine" :
4 publications dans cette catégorie
Affiliations :
Instituto de Salud Carlos III, Av. de Monforte de Lemos, 5, 28029 Madrid, Spain.
Publications dans "Lamivudine" :
Benign prostatic hyperplasia (BPH) is the most common cause of bladder outlet obstruction in men over the age of 50 years. An association between the prostate specific antigen (PSA), International Pro...
To determine the correlation between the PSA, IPSS and PV in men of African descent....
This was a cross sectional analysis involving 92 patients diagnosed as having symptomatic BPH at the Ho Teaching Hospital....
The data were collected using standardised questionnaires. The IPSS determined urinary symptom severity. The PV was determined using a transabdominal ultrasound machine. Serum PSA was retrieved from t...
The mean PV was 61.04 cm3 ± 21.95 cm3, the mean PSA was 4.21 ng/mL ± 3.85 ng/mL, and mean IPSS of 21.59 ± 3.78. The Pearson's correlation between PV and PSA was 0.283 (p = 0.01), between PV and IPSS w...
This study showed that serum PSA has a positive correlation with PV. However, IPSS had no significant association with PSA or PV in patients with BPH.Contribution: This study provides insights into th...
We report the case of a 63-year-old male who came to the urology clinic with an increasing value of the prostate specific antigen and an asymmetrical enlargement at the digital rectal examination. The...
To compare the cost effectiveness of prostatic artery embolization (PAE) with that of transurethral resection of the prostate (TURP) for the treatment of medically refractory benign prostatic hyperpla...
A cost-effectiveness analysis with Markov modeling was performed, comparing the clinical course after PAE with that after TURP for 3 years. Probabilities were obtained from the available literature, a...
Base case calculation showed comparable outcomes (PAE, 2.845 QALY; TURP, 2.854 QALY), with a cost difference of $3,104 (PAE, $2,934; TURP, $6,038). The incremental cost-effectiveness ratio was $360,24...
PAE is a cost-effective strategy to treat medically refractory BPH, resulting in comparable health benefits at a lower cost than that of TURP even when accounting for extreme alterations in adverse ev...
Prostate organogenesis begins during embryonic development and continues through puberty when the prostate becomes an important exocrine gland of the male reproductive system. The specification and gr...
Benign prostatic hyperplasia is associated with structural and morphological changes including elongation of prostatic urethral length. The aim of our study was to assess whether prostatic urethral le...
This prospective observational study was conducted over a 12-months duration. All the patients who presented with lower urinary tract symptoms secondary to benign prostatic hyperplasia were evaluated ...
A total of 153 patients were included in the study. Eighty-three (54.2%) patients underwent surgery during the study period. Prostate volume, intravesical prostatic protrusion, post-void residual volu...
BPH patients with longer PUL may require surgical management. PUL measured by TRUS may be a predicting factor for the need of surgery in BPH Keywords: Benign prostatic hyperplasia; lower urinary tract...
Biomarkers of DNA damage repair deficiency provide opportunities for personalized treatment with immunotherapy. However, there is limited research on the immune microenvironment of adeno-neuroendocrin...
A retrospective medical record review of 66 patients with prostate cancer (PCa) was performed. PCa samples from the 66 patients were analyzed using immunohistochemical staining for the detection of ch...
Twenty patients presented with adeno-NEPC, whereas 46 presented with adeno-PCa. The median age of patients at PCa diagnosis was 67.86 ± 7.05 years (68.65 ± 7.23 years, adeno-NEPC; 67.52 ± 7.02 years, ...
Our study revealed clinicopathological manifestations of adeno-NEPC and some possible predictive factors significantly associated with better outcomes in patients with adeno-NEPC. These findings might...
The purpose of the study was to evaluate the diagnostic significance of two new and a few clinical markers for prostate cancer (PCa) at various prostate volumes (PV)....
The study subjects were divided into two groups. Among them, there were 70 cases in the PV ≤30 ml group (benign prostatic hyperplasia [BPH]: 32 cases, PCa: 38 cases) and 372 cases in the PV > 30 ml gr...
In the PV ≤30 ml group, the diagnostic parameters based on prostate-specific antigen (PSA) had a decreased diagnostic significance for PCa. In the PV > 30 ml group, PSAD (AUC = 0.709), AVR (AVR = Age/...
Choosing appropriate indicators for different PVs could contribute to the early screening and diagnosis of PCa. The difference in the diagnostic value of two new indicators (A-PSAD and AVR), and PSAD ...
Holmium laser enucleation of the prostate (HoLEP) is a size-independent surgical option for treating benign prostatic hyperplasia (BPH) and lower urinary tract symptoms (LUTS) with excellent, durable ...
This study aims to compare the ability of the PHI versus tPSA test to predict the presence of PCa in our population....
A prospective observational study was performed. We included patients with tPSA ≥ 2.5 ng/ml, biopsy naïve or previous negative biopsy, undergoing a blood test, which includes tPSA, fPSA, and p2PSA, an...
140 men were included. Fifty-seven (40.7%) had a positive prostate biopsy result (Group A), and 83 (59.3%) had a negative biopsy result (Group B). The mean age was similar in both groups (mean ± stand...
The PHI test improves PCa detection compared to tPSA in our population....
We compare Prostate Health Index, Prostate Health Index density, and PSA density in predicting clinically significant prostate cancer in MRI-guided prostate biopsy....
This is a multicenter evaluation of prospectively maintained prostate biopsy databases at 10 urology centers. Men with Prostate Health Index and MRI-guided targeted and systematic prostate biopsy perf...
A total of 1,215 men were analyzed. Prostate cancer and clinically significant prostate cancer were diagnosed in 51% (617/1,215) and 35% (422/1,215) of men, respectively. Clinically significant prosta...
Prostate Health Index density outperformed Prostate Health Index or PSA density in clinically significant prostate cancer detection in men with multiparametric MRI performed, and further reduced unnec...