Communication autocrine : Questions médicales fréquentes
Nom anglais: Autocrine Communication
Descriptor UI:D019898
Tree Number:G04.085.100
Termes MeSH sélectionnés :
Cerebral Angiography
Questions fréquentes et termes MeSH associés
Diagnostic
5
#1
Comment diagnostiquer une communication autocrine ?
Le diagnostic repose sur des tests biologiques et des analyses de signalisation cellulaire.
Signalisation cellulaireBiomarqueurs
#2
Quels tests sont utilisés pour évaluer la communication autocrine ?
Des tests de culture cellulaire et des dosages de cytokines peuvent être utilisés.
CytokinesCulture cellulaire
#3
Y a-t-il des marqueurs spécifiques pour la communication autocrine ?
Oui, des marqueurs comme les récepteurs de cytokines peuvent indiquer une communication autocrine.
Récepteurs de cytokinesMarqueurs biologiques
#4
La communication autocrine est-elle visible par imagerie ?
Elle n'est généralement pas visible par imagerie, mais des techniques avancées peuvent aider.
Imagerie médicaleTechniques avancées
#5
Quels sont les signes d'une dérégulation autocrine ?
Des signes incluent une croissance cellulaire anormale ou une inflammation persistante.
InflammationCroissance cellulaire
Symptômes
5
#1
Quels symptômes indiquent une communication autocrine anormale ?
Des symptômes peuvent inclure des douleurs, des inflammations ou des tumeurs.
DouleurTumeurs
#2
La communication autocrine affecte-t-elle le métabolisme ?
Oui, elle peut influencer le métabolisme cellulaire et provoquer des déséquilibres.
MétabolismeDéséquilibres
#3
Y a-t-il des symptômes spécifiques liés à l'autocrine dans le cancer ?
Oui, des symptômes comme la fatigue et la perte de poids peuvent être présents.
CancerFatigue
#4
Comment la communication autocrine influence-t-elle l'immunité ?
Elle peut moduler la réponse immunitaire, entraînant une inflammation ou une immunosuppression.
ImmunitéInflammation
#5
Des symptômes neurologiques peuvent-ils être liés à l'autocrine ?
Oui, des troubles neurologiques peuvent survenir en raison de la signalisation autocrine.
Troubles neurologiquesSignalisation
Prévention
5
#1
Comment prévenir les dérégulations autocrines ?
Une alimentation équilibrée et un mode de vie sain peuvent aider à prévenir ces dérégulations.
AlimentationMode de vie sain
#2
Y a-t-il des mesures préventives spécifiques pour le cancer ?
Oui, éviter les carcinogènes et maintenir un poids santé sont des mesures préventives.
CarcinogènesPoids santé
#3
L'exercice physique aide-t-il à réguler l'autocrine ?
Oui, l'exercice régulier peut moduler la signalisation autocrine et améliorer la santé cellulaire.
Exercice physiqueSanté cellulaire
#4
Le stress influence-t-il la communication autocrine ?
Oui, le stress chronique peut perturber la communication autocrine et affecter la santé.
StressSanté
#5
Des compléments alimentaires peuvent-ils aider ?
Certains compléments, comme les oméga-3, peuvent moduler la communication autocrine.
Compléments alimentairesOméga-3
Traitements
5
#1
Quels traitements ciblent la communication autocrine ?
Des thérapies ciblées et des inhibiteurs de signalisation peuvent être utilisés.
Thérapies cibléesInhibiteurs
#2
Les médicaments peuvent-ils moduler la communication autocrine ?
Oui, certains médicaments peuvent inhiber ou stimuler la signalisation autocrine.
MédicamentsSignalisation
#3
Y a-t-il des traitements spécifiques pour le cancer liés à l'autocrine ?
Des traitements comme les anticorps monoclonaux ciblent souvent la communication autocrine dans le cancer.
Anticorps monoclonauxCancer
#4
Comment la thérapie génique influence-t-elle l'autocrine ?
La thérapie génique peut corriger des dérégulations dans la communication autocrine.
Thérapie géniqueDérégulations
#5
Les traitements hormonaux affectent-ils la communication autocrine ?
Oui, les traitements hormonaux peuvent influencer la signalisation autocrine dans certaines pathologies.
Traitements hormonauxPathologies
Complications
5
#1
Quelles complications peuvent résulter d'une communication autocrine anormale ?
Des complications incluent des cancers, des maladies auto-immunes et des inflammations chroniques.
CancersMaladies auto-immunes
#2
La communication autocrine peut-elle entraîner des troubles métaboliques ?
Oui, une dérégulation peut provoquer des troubles métaboliques comme le diabète.
Troubles métaboliquesDiabète
#3
Y a-t-il des risques d'inflammation chronique ?
Oui, une communication autocrine anormale peut entraîner une inflammation chronique.
Inflammation chroniqueRisques
#4
Comment la communication autocrine affecte-t-elle le cancer ?
Elle peut favoriser la croissance tumorale et la résistance aux traitements anticancéreux.
Croissance tumoraleRésistance aux traitements
#5
Des complications neurologiques sont-elles possibles ?
Oui, des dérégulations peuvent entraîner des troubles neurologiques et cognitifs.
Troubles neurologiquesCognitifs
Facteurs de risque
5
#1
Quels sont les facteurs de risque de dérégulation autocrine ?
Les facteurs incluent l'âge, l'obésité, le tabagisme et l'exposition à des toxines.
ObésitéTabagisme
#2
L'alimentation influence-t-elle la communication autocrine ?
Oui, une alimentation riche en sucres et graisses peut perturber la signalisation autocrine.
AlimentationSucres
#3
Le stress est-il un facteur de risque ?
Oui, le stress chronique peut augmenter le risque de dérégulation autocrine.
StressRisque
#4
Y a-t-il des prédispositions génétiques ?
Certaines mutations génétiques peuvent prédisposer à des dérégulations autocrines.
Mutations génétiquesPrédispositions
#5
L'exposition à des produits chimiques est-elle un risque ?
Oui, l'exposition à des produits chimiques toxiques peut augmenter le risque de dérégulation.
Produits chimiquesToxiques
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},
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"position": 17,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, certains médicaments peuvent inhiber ou stimuler la signalisation autocrine."
}
},
{
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"position": 18,
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"text": "Des traitements comme les anticorps monoclonaux ciblent souvent la communication autocrine dans le cancer."
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},
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}
},
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"position": 21,
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},
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"position": 22,
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"text": "Oui, une dérégulation peut provoquer des troubles métaboliques comme le diabète."
}
},
{
"@type": "Question",
"name": "Y a-t-il des risques d'inflammation chronique ?",
"position": 23,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une communication autocrine anormale peut entraîner une inflammation chronique."
}
},
{
"@type": "Question",
"name": "Comment la communication autocrine affecte-t-elle le cancer ?",
"position": 24,
"acceptedAnswer": {
"@type": "Answer",
"text": "Elle peut favoriser la croissance tumorale et la résistance aux traitements anticancéreux."
}
},
{
"@type": "Question",
"name": "Des complications neurologiques sont-elles possibles ?",
"position": 25,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, des dérégulations peuvent entraîner des troubles neurologiques et cognitifs."
}
},
{
"@type": "Question",
"name": "Quels sont les facteurs de risque de dérégulation autocrine ?",
"position": 26,
"acceptedAnswer": {
"@type": "Answer",
"text": "Les facteurs incluent l'âge, l'obésité, le tabagisme et l'exposition à des toxines."
}
},
{
"@type": "Question",
"name": "L'alimentation influence-t-elle la communication autocrine ?",
"position": 27,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, une alimentation riche en sucres et graisses peut perturber la signalisation autocrine."
}
},
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"name": "Le stress est-il un facteur de risque ?",
"position": 28,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, le stress chronique peut augmenter le risque de dérégulation autocrine."
}
},
{
"@type": "Question",
"name": "Y a-t-il des prédispositions génétiques ?",
"position": 29,
"acceptedAnswer": {
"@type": "Answer",
"text": "Certaines mutations génétiques peuvent prédisposer à des dérégulations autocrines."
}
},
{
"@type": "Question",
"name": "L'exposition à des produits chimiques est-elle un risque ?",
"position": 30,
"acceptedAnswer": {
"@type": "Answer",
"text": "Oui, l'exposition à des produits chimiques toxiques peut augmenter le risque de dérégulation."
}
}
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}
Department of Dermatology and the USC-Norris Comprehensive Cancer Center, University of Southern California Keck Medical Centre, Los Angeles, CA, 90033, USA.
Department of Biological Sciences, University of Calgary, 2500 University Drive NW, Calgary, Alberta, T2N 1N4, Canada. Electronic address: Habibi@ucalgary.ca.
Sbarro Institute for Cancer Research and Molecular Medicine and Center for Biotechnology, Biology Department, Temple University, Philadelphia, PA, 19122, USA. pscalia@isoprog.org.
Istituto Somatogene Per la Ricerca Onco-Genomica, ISOPROG, Caltanissetta, 93100, Italy. pscalia@isoprog.org.
Somatolink Research Foundation, Philadelphia, PA, 19102, USA. pscalia@isoprog.org.
Sbarro Institute for Cancer Research and Molecular Medicine and Center for Biotechnology, Biology Department, Temple University, Philadelphia, PA, 19122, USA.
Department of Medical Biotechnology, University of Siena, Siena, 53100, Italy.
Sbarro Institute for Cancer Research and Molecular Medicine and Center for Biotechnology, Biology Department, Temple University, Philadelphia, PA, 19122, USA.
Istituto Somatogene Per la Ricerca Onco-Genomica, ISOPROG, Caltanissetta, 93100, Italy.
Somatolink Research Foundation, Philadelphia, PA, 19102, USA.
Despite previous studies indicating a moderate/high incidence of angiography headache (AH), there is still limited data about the risk factors associated with its occurrence....
The present study aimed to assess the associations among demographic, clinical, and technical characteristics of cerebral digital subtraction angiography (DSA) and the occurrence of AH....
Cross-sectional analytical observational study with a sample comprised of individuals with a recommendation for elective DSA. Clinical interviews were conducted to assess the occurrence of AH, using a...
Among 114 subjects, the mean age was 52.8 (±13.8) years old, 75.4% (86/114) were women, 29.8% (34/114) had a history of migraines, and 10.5% (12/114) had chronic headaches. The overall frequency of AH...
3D angiography is strongly associated with the occurrence of AH, which has never been reported before. The association between a previous history of migraine and AH confirms the results of previous st...
Many large randomized trials in interventional cardiology have shown a significant advantage of transradial access (TRA) over transfemoral access (TFA). However, TRA has yet been widely used in Neurov...
A total of 380 patients underwent cerebral angiography in our center between January 2019 and January 2021. Among them, 192 patients underwent TRA, and 188 patients via TFA. The success rate of cerebr...
The operative success (94.27% vs 97.87%;...
TRA is effective and safe in cerebral angiography, and its use may be expanded....
Cerebral angiography through the transradial approach (TRA) is associated with a low risk of complications, but in rare cases, these complications can be life-threatening....
A 56-year-old female patient was admitted for transradial cerebral angiography due to the complaint of right limb weakness and the diagnosis of cerebral infarction and cerebral artery stenosis. During...
Mediastinal and thoracic hematoma may occur due to vessel perforation during TRA cerebral angiography, in which guidewire advancement must be cautious. Early detection and appropriate countermeasures ...
To evaluate the static and dynamic features of blood blister-like aneurysms (BBAs) using cerebral angiography to identify characteristic features to improve the diagnosis of these uncommon aneurysms....
Digital subtraction angiography (DSA) images were compared between patients with BBAs (n = 12, group A) and patients with unruptured paraclinoid aneurysms ≤ 5 mm in size treated by endovascular proced...
Compared to the group B, group A had a higher proportion of irregular vessel diameter (p = 0.013) and the delayed contrast medium outflow (p = 0.014). As well, stagnation of contrast medium along the ...
Irregular morphological features of the parent artery and delayed contrast medium outflow as characteristic findings of ruptured BBAs may improve the diagnosis of these uncommon aneurysms, which remai...
Trans-radial (TRA) access has become increasingly prevalent in neurointervention. Nonetheless, mediastinal hematoma after TRA is an infrequent yet grave complication associated with a notably elevated...
Carotid computed tomography angiography (CTA) showed calcified plaques with stenosis (Left: Severe, Right: Moderate) in the bilateral internal carotid arteries (ICAs) of an 81-year-old male presented ...
This case underscores the need for timely identification and precise manipulation of guidewires and guide-catheters through trans-radial access. The critical components of successful neuro-interventio...
The performance of a novel prototype four-dimensional (4D) digital subtraction angiography (DSA) for cerebral arteriovenous malformation (AVM) diagnosis was evaluated and compared with that of two-dim...
In this retrospective study, 37 consecutive cerebral AVM patients were included. The standard diagnostic results were concluded from the 2D and 3D DSA. Two 4D DSA volumes were reconstructed for each p...
Complete agreement was achieved between 4D DSA and 2D and 3D DSA in SM Grading Scale and intracranial aneurysm identification (agreement coefficient: 1) for both reviewers. The agreement coefficients ...
The performance of this prototype 4D DSA in cerebral AVMs diagnosis was largely equivalent to that of 2D and 3D DSA combination. Four-dimensional DSA can be regarded as a very good complement for 2D D...
To evaluate factors that influence the successful cannulation of intracranial vessels using a transradial approach....
A total of 61 transradial diagnostic angiograms were evaluated in a tertiary care center from July 2020 to December 2021. We evaluated the learning curve and aortic arch vessel factors that may influe...
Learning curve for the procedure was established after 21 cases. We were successful in cannulating the supra-aortic arteries except in 4 cases where we were unable to cannulate the left VA (vertebral ...
Transradial approach is a feasible and safe approach for performing cerebral angiography. Multiple factors can influence the procedure time and successful cannulation of intracranial vessels. With the...
The transradial approach (TRA) has become popular for diagnostic cerebral angiography. However, this approach is still used less often because of problematic formation of the Simmons catheter. The pur...
This retrospective study included consecutive patients eligible for right TRA cerebral angiography at our institution from 2021. To introduce the technique, the cerebral angiogram of formation of the ...
In total, 295 cerebral angiographies were evaluated. There were 155 (52.5 %), 83 (28.1 %), 39 (13.2 %), and 18 (6.1 %) patients with types I, II, and III aortic arches and bovine arch, respectively. T...
Pigtail catheter exchange may be an effective and safe technique for right TRA cerebral angiography. The findings of this report prompted institutions to apply this technique clinically and can serve ...
Cerebral angiography is the gold standard for diagnosing moyamoya disease (MMD), whereas magnetic resonance (MR) imaging/angiography is becoming more popular in the field of cerebrovascular disease du...
We analyzed 160 consecutive direct/indirect combined revascularization procedures for MMD preoperatively assessed using MR imaging/angiography alone. Perioperative complications were assessed for up t...
Sixty-four revascularization procedures were performed in 38 children, and 96 procedures were performed in 68 adults. There was no difference in the incidence of perioperative ischemic complications b...
Direct/indirect combined revascularization surgery based on our preoperative diagnostic protocol with the MR-first strategy resulted in favorable outcomes in pediatric MMD patients with relatively low...
Computed tomography (CT) angiography (CTA) is a non-invasive imaging method used to detect arteries and examine various brain diseases. When CTA is performed for follow-up or postoperative evaluation,...
To assess the differences between inter-operator arterial contrast enhancement in cerebral CTA using Bayesian statistical modeling....
Image data were obtained using a multistage sampling method from the cerebral CTA scans of patients who underwent the process between January 2015 and December 2018. Several Bayesian statistical model...
The posterior distributions showed that all parameters representing the difference between operators included zero at the 95% credible intervals (CIs). The maximum mean difference between inter-operat...
The Bayesian statistical modeling results suggest that contrast enhancement of cerebral CTA examination between operator-to-operator differences in postcontrast CT number was small compared to those w...
