Titre : Protéines d'activation de la GTPase

Protéines d'activation de la GTPase : Questions médicales fréquentes

Nom anglais: GTPase-Activating Proteins

Descriptor UI: D020690

Tree Number: D12.776.476.325.150

Questions fréquentes et termes MeSH associés

Général 1

#1

Erreur lors de la génération.

Veuillez réessayer ultérieurement.
GTPase-Activating Proteins
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Dr Olivier Menir

Contenu validé par Dr Olivier Menir

Expert en Médecine, Optimisation des Parcours de Soins et Révision Médicale

Validation scientifique effectuée le 21/04/2025

Contenu vérifié selon les dernières recommandations médicales

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Sous-catégories

3 au total
└─

Protéines d'activation de la ras GTPase

ras GTPase-Activating Proteins D020703 - D12.776.476.325.150.500
└─

Protéines RGS

RGS Proteins D020710 - D12.776.476.325.150.750
└─└─

Protéine p120 d'activation de la ras GTPase

p120 GTPase Activating Protein D020729 - D12.776.476.325.150.500.500

Auteurs principaux

René Rasche

2 publications dans cette catégorie

Affiliations :
  • Institute of Biochemistry, University Münster, Germany.
Publications dans "Protéines d'activation de la GTPase" :

Daniel Kümmel

2 publications dans cette catégorie

Affiliations :
  • Institute of Biochemistry, University Münster, Germany.
Publications dans "Protéines d'activation de la GTPase" :

Manil Kanade

2 publications dans cette catégorie

Affiliations :
  • Indian Institute of Science Education and Research, Pune, India.
Publications dans "Protéines d'activation de la GTPase" :

Pananghat Gayathri

2 publications dans cette catégorie

Affiliations :
  • Indian Institute of Science Education and Research, Pune, India.
Publications dans "Protéines d'activation de la GTPase" :

Qingqing Dai

2 publications dans cette catégorie

Affiliations :
  • Department of Internal Medicine IV (Gastroenterology, Hepatology, and Infectious Diseases), Jena University Hospital, Jena, Germany.
  • Else Kröner Graduate School for Medical Students "Jena School for Ageing Medicine (JSAM)", Jena University Hospital, Jena, Germany.
Publications dans "Protéines d'activation de la GTPase" :

Fei Song

2 publications dans cette catégorie

Affiliations :
  • Department of Urology, Jena University Hospital, Jena, Germany.
Publications dans "Protéines d'activation de la GTPase" :

Jun Matsuda

2 publications dans cette catégorie

Affiliations :
  • Division of Nephrology, McGill University Health Centre, Montreal, Quebec, Canada; Research Institute, McGill University Health Centre, Montreal, Quebec, Canada.
Publications dans "Protéines d'activation de la GTPase" :

Tomoko Takano

2 publications dans cette catégorie

Affiliations :
  • Division of Nephrology, McGill University Health Centre, Montreal, Quebec, Canada; Research Institute, McGill University Health Centre, Montreal, Quebec, Canada. Electronic address: tomoko.takano@mcgill.ca.
Publications dans "Protéines d'activation de la GTPase" :

Qiaojia Zheng

2 publications dans cette catégorie

Affiliations :
  • Marine and Agricultural Biotechnology Laboratory, Institute of Oceanography, Minjiang University, Fuzhou, China.
Publications dans "Protéines d'activation de la GTPase" :

Zhi Yu

2 publications dans cette catégorie

Affiliations :
  • Marine and Agricultural Biotechnology Laboratory, Institute of Oceanography, Minjiang University, Fuzhou, China.
  • College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Publications dans "Protéines d'activation de la GTPase" :

Yanping Yuan

2 publications dans cette catégorie

Affiliations :
  • College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Publications dans "Protéines d'activation de la GTPase" :

Danli Sun

2 publications dans cette catégorie

Affiliations :
  • Marine and Agricultural Biotechnology Laboratory, Institute of Oceanography, Minjiang University, Fuzhou, China.
Publications dans "Protéines d'activation de la GTPase" :

Yakubu Saddeeq Abubakar

2 publications dans cette catégorie

Affiliations :
  • Department of Biochemistry, Faculty of Life Sciences, Ahmadu Bello University, Zaria, Nigeria.
Publications dans "Protéines d'activation de la GTPase" :

Jie Zhou

2 publications dans cette catégorie

Affiliations :
  • College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Publications dans "Protéines d'activation de la GTPase" :

Zonghua Wang

2 publications dans cette catégorie

Affiliations :
  • Marine and Agricultural Biotechnology Laboratory, Institute of Oceanography, Minjiang University, Fuzhou, China.
  • College of Life Sciences, Fujian Agriculture and Forestry University, Fuzhou, China.
Publications dans "Protéines d'activation de la GTPase" :

Huawei Zheng

2 publications dans cette catégorie

Affiliations :
  • Marine and Agricultural Biotechnology Laboratory, Institute of Oceanography, Minjiang University, Fuzhou, China.
Publications dans "Protéines d'activation de la GTPase" :

Lorna O'Donoghue

1 publication dans cette catégorie

Affiliations :
  • UCD School of Medicine, University College Dublin, UCD Conway Institute, Belfield, Dublin 4, Ireland.
  • Irish Centre for Vascular Biology, Royal College of Surgeons in Ireland, 123 St. Stephen's Green 123, Dublin 2, Ireland.
Publications dans "Protéines d'activation de la GTPase" :

Albert Smolenski

1 publication dans cette catégorie

Affiliations :
  • UCD School of Medicine, University College Dublin, UCD Conway Institute, Belfield, Dublin 4, Ireland.
  • Irish Centre for Vascular Biology, Royal College of Surgeons in Ireland, 123 St. Stephen's Green 123, Dublin 2, Ireland.
Publications dans "Protéines d'activation de la GTPase" :

Yu Huang

1 publication dans cette catégorie

Affiliations :
  • Institute of Modern Biopharmaceuticals, State Key Laboratory Breeding Base of Eco-Environment and Bio-Resource of the Three Gorges Area, Key Laboratory of Eco-Environments in Three Gorges Reservoir Region, Ministry of Education, School of Life Sciences, Southwest University, Chongqing, China.
Publications dans "Protéines d'activation de la GTPase" :

Shuangquan Yan

1 publication dans cette catégorie

Affiliations :
  • Institute of Modern Biopharmaceuticals, State Key Laboratory Breeding Base of Eco-Environment and Bio-Resource of the Three Gorges Area, Key Laboratory of Eco-Environments in Three Gorges Reservoir Region, Ministry of Education, School of Life Sciences, Southwest University, Chongqing, China.
Publications dans "Protéines d'activation de la GTPase" :

Sources (10000 au total)

Mycobacterium Fluoroquinolone Resistance Protein D (MfpD), a GTPase-Activating Protein of GTPase MfpB, Is Involved in Fluoroquinolones Potency.

21 12 2022
DOI: 10.1128/spectrum.02098-22 PMID: 36453945

Tuberculosis (TB) caused by Mycobacterium tuberculosis infection remains one of the most serious global health problems. Fluoroquinolones (FQs) are an important component of drug regimens against mult...

Humans Antitubercular Agents Fluoroquinolones GTP Phosphohydrolases GTPase-Activating Proteins +3 autres

Comprehensive analysis of the expression and prognosis for IQ motif-containing GTPase-activating proteins in hepatocellular carcinoma.

01 Nov 2022
DOI: 10.1186/s12885-022-10204-3 PMID: 36320006

IQ motif-containing GTPase-activating proteins (IQGAPs) are a group of scaffold proteins which have been identified to be involved in tumor initiation and progression in diverse types of cancer. Clini... We analyzed the transcriptional and survival data of IQGAPs in HCC patients using Oncomine, UALCAN, Kaplan-Meier Plotter, cBioPortal, and GeneMANIA. We further examined tumor and adjacent normal tissu... We found that the expression levels of IQGAP1 and 3 were significantly elevated in HCC tissues than in normal liver tissues, whereas the expression level of IQGAP2 was decreased in the former than in ... IQGAPs may serve as new prognostic biomarkers and potential targets for precision therapy in HCC....

Humans Carcinoma, Hepatocellular Liver Neoplasms GTPase-Activating Proteins Neoplasm Recurrence, Local +3 autres

Rho GTPase-activating protein 10 (ARHGAP10/GRAF2) is a novel autoantibody target in patients with autoimmune encephalitis.

Oct 2022
DOI: 10.1007/s00415-022-11178-9 PMID: 35624318

In 2010, we described a novel immunoglobulin G (IgG) autoantibody (termed anti-Ca after the index case) targeting Rho GTPase-activating protein 26 (ARHGAP26, also termed GTPase regulator associated wi... To assess whether ARHGAP26-IgG/anti-Ca co-reacts with ARHGAP10.... Serological testing for ARHGAP10/GRAF2 autoantibodies by recombinant cell-based assays and isotype and IgG subclass analyses.... 26/31 serum samples (84%) from 9/12 (75%) ARHGAP26-IgG/anti-Ca-positive patients and 4/6 ARHGAP26-IgG/anti-Ca-positive CSF samples from four patients were positive also for ARHGAP10-IgG. ARHGAP10-IgG ... We demonstrate that a substantial proportion of patients with ARHGAP26-IgG/anti-Ca-positive autoimmune encephalitis co-react with ARHGAP10. Further studies on the clinical and diagnostic implications ...

Autoantibodies Cerebellar Ataxia Encephalitis GTPase-Activating Proteins Hashimoto Disease +2 autres